Jorg Goronzy

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. doi request reprint Understanding immunosenescence to improve responses to vaccines
    Jorg J Goronzy
    The Department of Medicine, Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, California, USA
    Nat Immunol 14:428-36. 2013
  2. pmc Signaling pathways in aged T cells - a reflection of T cell differentiation, cell senescence and host environment
    Jorg J Goronzy
    Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, United States
    Semin Immunol 24:365-72. 2012
  3. pmc Giant cell arteritis: immune and vascular aging as disease risk factors
    Shalini V Mohan
    Department of Medicine, Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA 94305 5166, USA
    Arthritis Res Ther 13:231. 2011
  4. doi request reprint Immune aging and autoimmunity
    Jorg J Goronzy
    Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, 269 Campus Drive West, Stanford, CA, 94305 5166, USA
    Cell Mol Life Sci 69:1615-23. 2012

Research Grants

  1. T CELLS AND AGING
    Jorg Goronzy; Fiscal Year: 2002
  2. DIVERSITY OF T LYMPHOCYTES IN RHEUMATOID ARTHRITIS
    Jorg Goronzy; Fiscal Year: 2006
  3. T CELLS AND AGING
    Jorg Goronzy; Fiscal Year: 2007
  4. DIVERSITY OF T LYMPHOCYTES IN RHEUMATOID ARTHRITIS
    Jorg Goronzy; Fiscal Year: 2001

Collaborators

  • Shalini V Mohan
  • Y Joyce Liao
  • Cornelia M Weyand
  • Jonathan W Kim

Detail Information

Publications4

  1. doi request reprint Understanding immunosenescence to improve responses to vaccines
    Jorg J Goronzy
    The Department of Medicine, Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, California, USA
    Nat Immunol 14:428-36. 2013
    ....
  2. pmc Signaling pathways in aged T cells - a reflection of T cell differentiation, cell senescence and host environment
    Jorg J Goronzy
    Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, United States
    Semin Immunol 24:365-72. 2012
    ..Prominent examples are the expression of negative regulatory receptors of the CD28 and the TNF receptor superfamilies as well the expression of various cytoplasmic and nuclear dual-specific phosphatases...
  3. pmc Giant cell arteritis: immune and vascular aging as disease risk factors
    Shalini V Mohan
    Department of Medicine, Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA 94305 5166, USA
    Arthritis Res Ther 13:231. 2011
    ..Thus, the aging process impacts the two major biologic systems that liaise to promote giant cell arteritis; the immune system and the vessel wall niche...
  4. doi request reprint Immune aging and autoimmunity
    Jorg J Goronzy
    Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, 269 Campus Drive West, Stanford, CA, 94305 5166, USA
    Cell Mol Life Sci 69:1615-23. 2012
    ....

Research Grants23

  1. T CELLS AND AGING
    Jorg Goronzy; Fiscal Year: 2002
    ..Preventing the accumulation of CD4+ CD28null T cells might be a primary target for immune therapy in aging individuals. ..
  2. DIVERSITY OF T LYMPHOCYTES IN RHEUMATOID ARTHRITIS
    Jorg Goronzy; Fiscal Year: 2006
    ..The long-term goal of this proposal is to determine whether this novel regulatory system of stimulatory and inhibitory receptors can be exploited for therapeutic interventions to control disease-relevant T-cell responses in RA. ..
  3. T CELLS AND AGING
    Jorg Goronzy; Fiscal Year: 2007
    ..The promise of this concept is that targeting these active mechanisms can, in part, restore immunocompetence. ..
  4. DIVERSITY OF T LYMPHOCYTES IN RHEUMATOID ARTHRITIS
    Jorg Goronzy; Fiscal Year: 2001
    ..In combination, these approaches will allow us to determine how autoreactive CD4+ CD28- T cells are clonally expanded in RA patients and how they function in the rheumatoid inflammation. ..