Research Topics
| Lawrence T GoodnoughSummaryAffiliation: Stanford University Country: USA Publications
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Detail Information
Publications
Detection, evaluation, and management of anemia in the elective surgical patientLawrence T Goodnough
Department of Pathology, Stanford University Medical Center, 300 Pasteur Drive H 1402, Stanford, CA 94305 5626, USA
Anesth Analg 101:1858-61. 2005....
Complement (C1q) fixing solid-phase screening for HLA antibodies increases the availability of compatible platelet components for refractory patientsMagali J Fontaine
Department of Pathology, Stanford Hospital and Clinics, Stanford University, Stanford, California 94305 5626, USA
Transfusion 51:2611-8. 2011..We hypothesized that the C1q-SAB method might be more relevant than the IgG-SAB method because the antibodies identified may activate the complement cascade causing PLT destruction...
Improving platelet supply chains through collaborations between blood centers and transfusion servicesMagali J Fontaine
Department of Pathology, Stanford University Medical Center, Stanford, California 94305 5626, USA
Transfusion 49:2040-7. 2009....
Impact of cytomegalovirus (CMV) antibody reflex testing in the transfusion service on management of CMV-seronegative blood inventoryMagali J Fontaine
Department of Pathology, Stanford University, and Stanford Hospital and Clinics, Stanford, California, USA
Transfusion 50:1685-9. 2010..Our goal is to minimize unnecessary cytomegalovirus (CMV)-seronegative blood transfusion to preserve the CMV-seronegative blood inventory for patients who are identified as CMV seronegative...
Quality management in the transfusion service: case studies in process improvementLawrence T Goodnough
Department of Pathology, Stanford University School of Medicine, Stanford University Medical Center, Stanford, California 94305, USA
Transfusion 51:600-9. 2011..Laboratory-based quality improvement (QI) initiatives can improve clinical outcomes and patient safety...
Blood and blood conservation: a national perspectiveLawrence T Goodnough
Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA
J Cardiothorac Vasc Anesth 18:6S-11S. 2004
How we treat: transfusion medicine support of obstetric servicesLawrence T Goodnough
Department of Pathology and Medicine and Obstetrics and Anesthesiology, Stanford University School of Medicine, Stanford, California 94305, USA
Transfusion 51:2540-8. 2011..Obstetric services depend on the transfusion service (TS) to provide diagnostic testing and blood component therapy for clinical care pathways...
Autologous blood donationLawrence T Goodnough
Department of Pathology, Stanford University School of Medicine, 300 Pasteur Drive, H 1402, Stanford, CA 94305 5626, USA
Anesthesiol Clin North America 23:263-70, vi. 2005..Nevertheless, the continuing emergence of new pathogens and the potential for severe blood inventory shortages continue to give preoperative autologous blood donation an important role in blood conservation strategies...
Risks of blood transfusionLawrence T Goodnough
Department of Pathology, Stanford University School of Medicine, 300 Pasteur Drive, H 1402 Stanford, CA 94305 5324, USA
Anesthesiol Clin North America 23:241-52, v. 2005..Pathogen inactivation technologies and reactive strategies such as nucleic acid testing ensure continued advances in blood safety...
Massive transfusion protocols for patients with substantial hemorrhagePampee P Young
Department of Pathology, Vanderbilt University School of Medicine, 1161 21st Ave South, C2217A MCN, Nashville, TN 37232, USA
Transfus Med Rev 25:293-303. 2011..However, the use of MTPs remains controversial. This review describes published experiences with MTPs and illustrates the potential value of several MTPs currently utilized by academic transfusion services...
Implementation of a two-specimen requirement for verification of ABO/Rh for blood transfusionLawrence T Goodnough
Department of Pathology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305 5626, USA
Transfusion 49:1321-8. 2009..This study presents our implementation of a two-specimen requirement with no prior record of ABO/Rh to verify patients' blood type before transfusion...
Blood ordering from the operating room: turnaround time as a quality indicatorColt M McClain
Department of Veterans Affairs Medical Center, Nashville, Tennessee, USA
Transfusion 53:41-8. 2013..We examined the TAT for issuing RBCs from the blood bank to the operating rooms (ORs) at Vanderbilt University Medical Center (VUMC) and Stanford University Medical Center (SUMC)...
Recombinant factor VIIa: an assessment of evidence regarding its efficacy and safety in the off-label settingAaron C Logan
Department of Medicine, Division of Hematology, Stanford University School of Medicine, Stanford, CA 94305, USA
Hematology Am Soc Hematol Educ Program 2010:153-9. 2010..We review the evidence regarding the efficacy and safety of this important, but controversial, hemostatic agent in the off-label setting...
Alloimmunization to red blood cell antigens affects clinical outcomes in liver transplant patientsScott D Boyd
Department of Pathology, Stanford University, and Department of Transfusion Medicine, Stanford University Hospitals and Clinics, CA 94305, USA
Liver Transpl 13:1654-61. 2007..Our findings suggest that blood transfusion and immune modulation greatly affect the survival of patients after liver transplantation...
Recombinant factor VIIa: safety and efficacyLawrence T Goodnough
Department of Pathology and Medicine, Stanford University, Stanford, California 94305 5626, USA
Curr Opin Hematol 14:504-9. 2007..Recombinant factor VIIa has been increasingly used to provide hemostasis in nonapproved indications. This trend has resulted in concerns about safety, efficacy and costs...
Age of blood as a limitation for transfusion: potential impact on blood inventory and availabilityMagali J Fontaine
Department of Pathology, Stanford University School of Medicine, Stanford University Medical Center, 300 Pasteur Drive, Room H1402, M C 5626, Stanford, CA 94305 5626, USA
Transfusion 50:2233-9. 2010..Evolving concerns about storage lesions for red blood cells (RBCs) have led to ongoing trials evaluating the benefits of transfusing fresher blood to acutely ill patients...
Rationale for blood conservationLawrence T Goodnough
Department of Pathology and Medicine, Transfusion Service, Stanford University Medical Center, Stanford, California 94305 5626, USA
Surg Infect (Larchmt) 6:S3-8. 2005..Exposure of patients to allogeneic blood transfusion can be minimized or avoided by the systematic use of multiple blood conservation techniques. Current use of these technologies is variable...
Blood managementLawrence T Goodnough
Department of Pathology and Medicine, Stanford University Medical Center, 300 Pasteur Dr, M C 5626, Stanford, CA 94305, USA
Arch Pathol Lab Med 131:695-701. 2007..We provide an overview of the principles of blood management: the appropriate use of blood and blood components, with a goal of minimizing their use...
Bloodless medicine: clinical care without allogeneic blood transfusionLawrence T Goodnough
Washington University School of Medicine, St. Louis, Missouri, USA
Transfusion 43:668-76. 2003
Evolution in alternatives to blood transfusionLawrence T Goodnough
Washington University School of Medicine, St Louis, MO 63110, USA
Hematol J 4:87-91. 2003
Risks of blood transfusionLawrence T Goodnough
Department of Medicine, Washington University School of Medicine, St Louis, MO 63110 1093, USA
Crit Care Med 31:S678-86. 2003....
Clinical benefits and risks associated with epoetin and darbepoetin in patients with chemotherapy-induced anemia: a systematic review of the literatureSusan D Ross
MetaWorks, Inc, Medford, Massachusetts 02155, USA
Clin Ther 28:801-31. 2006..Evidence-based guidelines and systematic reviews of the management of CIA do not yet include all currently approved ESPs or all of the clinically relevant benefits and risks of ESPs...
Autologous blood donationLawrence T Goodnough
Washington University School of Medicine, Transfusion Services, Barnes Jewish Hospital, St Louis, Missouri, USA
Crit Care 8:S49-52. 2004..It has been determined that preoperative autologous blood donation is poorly cost-effective; the use of this procedure must be based on evidence that it is safe and of value for the patient...
Anemia of chronic diseaseGuenter Weiss
Department of General Internal Medicine, Clinical Immunology and Infectious Diseases, Medical University of Innsbruck, Innsbruck, Austria
N Engl J Med 352:1011-23. 2005
Objectives and limitations of bloodless medical careAryeh Shander
Department of Anesthesiology and Critical Care and Hyperbaric Medicine, New Jersey Institute for the Advancement of Bloodless Medicine and Surgery, Englewood Hospital and Medical Center, Englewood, NJ 07631, USA
Curr Opin Hematol 13:462-70. 2006..To outline the rationale, limitations, and execution of bloodless medical and surgical programs, highlighting characteristics that contribute to successful outcomes...
Fatal thrombosis after administration of activated prothrombin complex concentrates in a patient supported by extracorporeal membrane oxygenation who had received activated recombinant factor VIIJack D Bui
Department of Pathology and Immunology, Washington University School of Medicine, 660 S. Euclid, St Louis, MO 63110, USA
J Thorac Cardiovasc Surg 124:852-4. 2002
Donor CMV serostatus has no impact on CMV viremia or disease when prophylactic granulocyte transfusions are given following allogeneic peripheral blood stem cell transplantationRavi Vij
Section of Bone Marrow Transplantation and Leukemia, Washington University School of Medicine, St Louis, MO 63110 1093, USA
Blood 101:2067-9. 2003..This knowledge may help expand the donor pool in areas with a high prevalence of CMV in the general population...
Issues in the management of cancer-related thrombocytopeniaLawrence T Goodnough
Departments of Medicine and Pathology and Immunology, Divisions of Laboratory Medicine and Oncology, Washington University School of Medicine, St Louis, Missouri 63110 1093, USA
Oncology (Williston Park) 16:1558-67; discussion 1570, 1572-4. 2002..These agents include recombinant human interleukin-11, recombinant human thrombopoietin, and c-Mpl ligand mimetics...
The rise and fall of preoperative autologous blood donation (editorial). Transfusion. 2001;41:1459-62Mark E Brecher
University of North Carolina HospitalsChapel Hill, NC 27514e-mail: Louis, MO
Transfusion 42:1618-22. 2002
Autoantibody formation after alloimmunization: are blood transfusions a risk factor for autoimmune hemolytic anemia?Pampee P Young
Department of Pathology and Immunology, Washington University School of Medicine, MO 63110, USA
Transfusion 44:67-72. 2004..The development of RBC autoantibodies resulting from or associated with allogeneic blood transfusions (i.e., RBC autoimmunization) is not a well-recognized complication of RBC transfusions...
Transfusion medicine: looking to the futureLawrence T Goodnough
Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
Lancet 361:161-9. 2003..Finally, serious difficulties in blood safety and availability for poor, developing countries require innovative strategies and commitment of resources...
The use of erythropoietin to increase red cell massLawrence T Goodnough
Division of Laboratory Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA
Can J Anaesth 50:S10-8. 2003
Red cell growth factors in patients with chronic anemiasLawrence T Goodnough
Division of Laboratory Medicine, Washington University School of Medicine, Box 8118, 660 S Euclid Avenue, St Louis, MO 63110, USA
Curr Hematol Rep 1:119-23. 2002....
Anemia: not just an innocent bystander?Allen R Nissenson
Arch Intern Med 163:1400-4. 2003
Update on transfusion medicineAryeh Shander
Department of Anesthesiology and Critical Care and Hyperbaric Medicine and the New Jersey Institute for the Advancement of Bloodless Medicine and Surgery, Englewood Hospital and Medical Center, Englewood, New Jersey 07631, USA
Pharmacotherapy 27:57S-68S. 2007..The benefits, risks, and several ongoing controversies that relate to the appropriateness and safety of blood product use are also summarized...
Anemia screening in elective surgery: definition, significance and patients' interestsAryeh Shander
Anesth Analg 103:778-9; author reply 779-80. 2006
Polymerized bovine hemoglobin solution as a replacement for allogeneic red blood cell transfusion after cardiac surgery: results of a randomized, double-blind trialJerrold H Levy
Emory University Hospital, Atlanta, GA, USA
J Thorac Cardiovasc Surg 124:35-42. 2002..In a third of cases, HBOC-201 eliminated the need for red blood cell transfusion, although substantial doses were needed to produce this modest degree of blood conservation...
