L T Goodnough

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. doi request reprint Rationale for blood conservation
    Lawrence T Goodnough
    Department of Pathology and Medicine, Transfusion Service, Stanford University Medical Center, Stanford, California 94305 5626, USA
    Surg Infect (Larchmt) 6:S3-8. 2005
  2. doi request reprint Concepts of blood transfusion in adults
    Lawrence T Goodnough
    Department of Pathology, Stanford University, Stanford, CA, USA
    Lancet 381:1845-54. 2013
  3. doi request reprint Update on erythropoiesis-stimulating agents
    Lawrence Tim Goodnough
    Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA
    Best Pract Res Clin Anaesthesiol 27:121-9. 2013
  4. doi request reprint Logistics of transfusion support for patients with massive hemorrhage
    Lawrence T Goodnough
    Department of Pathology, Stanford University, Stanford, California, USA
    Curr Opin Anaesthesiol 26:208-14. 2013
  5. doi request reprint Transfusion outcomes in patients undergoing coronary artery bypass grafting treated with prasugrel or clopidogrel: TRITON-TIMI 38 retrospective data analysis
    Lawrence T Goodnough
    Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305 5626, USA
    J Thorac Cardiovasc Surg 145:1077-1082.e4. 2013
  6. doi request reprint Current status of pharmacologic therapies in patient blood management
    Lawrence Tim Goodnough
    Pathology Department, Stanford University, 300 Pasteur Drive Room H 1402, M C 5626 Stanford, CA 94305, USA
    Anesth Analg 116:15-34. 2013
  7. doi request reprint Iron deficiency syndromes and iron-restricted erythropoiesis (CME)
    Lawrence Tim Goodnough
    Department of Pathology and Medicine, Stanford University School of Medicine, Stanford, CA, USA
    Transfusion 52:1584-92. 2012
  8. doi request reprint A reappraisal of plasma, prothrombin complex concentrates, and recombinant factor VIIa in patient blood management
    Lawrence Tim Goodnough
    Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305 5626, USA
    Crit Care Clin 28:413-26, vi-vii. 2012
  9. doi request reprint Operational, quality, and risk management in the transfusion service: lessons learned
    Lawrence Tim Goodnough
    Department of Pathology, Stanford University, Stanford, CA 94305, USA
    Transfus Med Rev 26:252-61. 2012
  10. doi request reprint Use of point-of-care testing for plasma therapy
    Lawrence Tim Goodnough
    Department of Pathology, Stanford University, and Transfusion Services, Stanford University Medical Center, Stanford, California 94305, USA
    Transfusion 52:56S-64S. 2012

Collaborators

Detail Information

Publications36

  1. doi request reprint Rationale for blood conservation
    Lawrence T Goodnough
    Department of Pathology and Medicine, Transfusion Service, Stanford University Medical Center, Stanford, California 94305 5626, USA
    Surg Infect (Larchmt) 6:S3-8. 2005
    ..Exposure of patients to allogeneic blood transfusion can be minimized or avoided by the systematic use of multiple blood conservation techniques. Current use of these technologies is variable...
  2. doi request reprint Concepts of blood transfusion in adults
    Lawrence T Goodnough
    Department of Pathology, Stanford University, Stanford, CA, USA
    Lancet 381:1845-54. 2013
    ..Nevertheless, institutional experience and national databases suggest that a restrictive blood transfusion approach is being increasingly implemented as best practice...
  3. doi request reprint Update on erythropoiesis-stimulating agents
    Lawrence Tim Goodnough
    Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA
    Best Pract Res Clin Anaesthesiol 27:121-9. 2013
    ..Despite current regulations restricting ESA use, these agents are an effective treatment of anaemia, particularly for those who would be transfusion dependent without ESA therapy...
  4. doi request reprint Logistics of transfusion support for patients with massive hemorrhage
    Lawrence T Goodnough
    Department of Pathology, Stanford University, Stanford, California, USA
    Curr Opin Anaesthesiol 26:208-14. 2013
    ..The review summarizes practical approaches for transfusion support of patients with massive hemorrhage...
  5. doi request reprint Transfusion outcomes in patients undergoing coronary artery bypass grafting treated with prasugrel or clopidogrel: TRITON-TIMI 38 retrospective data analysis
    Lawrence T Goodnough
    Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305 5626, USA
    J Thorac Cardiovasc Surg 145:1077-1082.e4. 2013
    ..The objective of the present study was to characterize a potential risk-adjusted difference in transfusion requirements between prasugrel and clopidogrel cohorts...
  6. doi request reprint Current status of pharmacologic therapies in patient blood management
    Lawrence Tim Goodnough
    Pathology Department, Stanford University, 300 Pasteur Drive Room H 1402, M C 5626 Stanford, CA 94305, USA
    Anesth Analg 116:15-34. 2013
    ..Reviewed here are the available pharmacologic tools for anemia and blood management: erythropoiesis-stimulating agents (ESAs), iron therapy, hemostatic agents, and potentially, artificial oxygen carriers...
  7. doi request reprint Iron deficiency syndromes and iron-restricted erythropoiesis (CME)
    Lawrence Tim Goodnough
    Department of Pathology and Medicine, Stanford University School of Medicine, Stanford, CA, USA
    Transfusion 52:1584-92. 2012
    ....
  8. doi request reprint A reappraisal of plasma, prothrombin complex concentrates, and recombinant factor VIIa in patient blood management
    Lawrence Tim Goodnough
    Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305 5626, USA
    Crit Care Clin 28:413-26, vi-vii. 2012
    ..This review summarizes these issues and provides insight regarding use of these options in management of refractory or massive bleeding...
  9. doi request reprint Operational, quality, and risk management in the transfusion service: lessons learned
    Lawrence Tim Goodnough
    Department of Pathology, Stanford University, Stanford, CA 94305, USA
    Transfus Med Rev 26:252-61. 2012
    ..Laboratory-based initiatives that improve patient safety and clinical outcomes need to have resources aligned with the personnel and time required for quality management and risk management...
  10. doi request reprint Use of point-of-care testing for plasma therapy
    Lawrence Tim Goodnough
    Department of Pathology, Stanford University, and Transfusion Services, Stanford University Medical Center, Stanford, California 94305, USA
    Transfusion 52:56S-64S. 2012
    ..In this review we summarize clinical evidence for the effectiveness of POCT, along with some future directions for this strategy...
  11. doi request reprint How I treat warfarin-associated coagulopathy in patients with intracerebral hemorrhage
    Lawrence Tim Goodnough
    Departments of Pathology and Medicine, Stanford University School of Medicine, Stanford, CA, USA
    Blood 117:6091-9. 2011
    ..In this review, we summarize the relevant literature about these controversies and present recommendations for management of patients with warfarin-associated coagulopathy and intracerebral hemorrhage...
  12. pmc Detection, evaluation, and management of preoperative anaemia in the elective orthopaedic surgical patient: NATA guidelines
    L T Goodnough
    Department of Pathology and Medicine, Stanford University School of Medicine, Pasteur Dr, Stanford, CA 94305, USA
    Br J Anaesth 106:13-22. 2011
    ..Anaemia should be viewed as a serious and treatable medical condition, rather than simply an abnormal laboratory value. Implementation of anaemia management in the elective orthopaedic surgery setting will improve patient outcomes...
  13. doi request reprint Implementation of a two-specimen requirement for verification of ABO/Rh for blood transfusion
    Lawrence T Goodnough
    Department of Pathology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305 5626, USA
    Transfusion 49:1321-8. 2009
    ..This study presents our implementation of a two-specimen requirement with no prior record of ABO/Rh to verify patients' blood type before transfusion...
  14. ncbi request reprint Transfusion triggers
    Lawrence Tim Goodnough
    Departments of Pathology and Medicine, Stanford University, Stanford, CA 94305, USA
    Surgery 142:S67-70. 2007
    ..The benefit of transfusion in relation to mortality and morbidity is discussed here based on an assessment of the literature, and transfusion guidelines from several organizations are summarized...
  15. ncbi request reprint Recombinant factor VIIa: safety and efficacy
    Lawrence T Goodnough
    Department of Pathology and Medicine, Stanford University, Stanford, California 94305 5626, USA
    Curr Opin Hematol 14:504-9. 2007
    ..Recombinant factor VIIa has been increasingly used to provide hemostasis in nonapproved indications. This trend has resulted in concerns about safety, efficacy and costs...
  16. ncbi request reprint Autologous blood donation
    Lawrence T Goodnough
    Department of Pathology, Stanford University School of Medicine, 300 Pasteur Drive, H 1402, Stanford, CA 94305 5626, USA
    Anesthesiol Clin North America 23:263-70, vi. 2005
    ..Nevertheless, the continuing emergence of new pathogens and the potential for severe blood inventory shortages continue to give preoperative autologous blood donation an important role in blood conservation strategies...
  17. ncbi request reprint Risks of blood transfusion
    Lawrence T Goodnough
    Department of Pathology, Stanford University School of Medicine, 300 Pasteur Drive, H 1402 Stanford, CA 94305 5324, USA
    Anesthesiol Clin North America 23:241-52, v. 2005
    ..Pathogen inactivation technologies and reactive strategies such as nucleic acid testing ensure continued advances in blood safety...
  18. ncbi request reprint Blood management
    Lawrence T Goodnough
    Department of Pathology and Medicine, Stanford University Medical Center, 300 Pasteur Dr, M C 5626, Stanford, CA 94305, USA
    Arch Pathol Lab Med 131:695-701. 2007
    ..We provide an overview of the principles of blood management: the appropriate use of blood and blood components, with a goal of minimizing their use...
  19. ncbi request reprint Erythropoietin and iron-restricted erythropoiesis
    Lawrence Tim Goodnough
    Department of Pathology, Stanford University, Stanford, CA 94305 5626, USA
    Exp Hematol 35:167-72. 2007
    ..Insights gained over the last 20 years regarding the relationship between erythropoietin, iron, and erythropoiesis, along with implications for clinical management, will be reviewed...
  20. ncbi request reprint Blood and blood conservation: a national perspective
    Lawrence T Goodnough
    Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA
    J Cardiothorac Vasc Anesth 18:6S-11S. 2004
  21. doi request reprint Improving platelet supply chains through collaborations between blood centers and transfusion services
    Magali J Fontaine
    Department of Pathology, Stanford University Medical Center, Stanford, California 94305 5626, USA
    Transfusion 49:2040-7. 2009
    ....
  22. doi request reprint Impact of cytomegalovirus (CMV) antibody reflex testing in the transfusion service on management of CMV-seronegative blood inventory
    Magali J Fontaine
    Department of Pathology, Stanford University, and Stanford Hospital and Clinics, Stanford, California, USA
    Transfusion 50:1685-9. 2010
    ..Our goal is to minimize unnecessary cytomegalovirus (CMV)-seronegative blood transfusion to preserve the CMV-seronegative blood inventory for patients who are identified as CMV seronegative...
  23. doi request reprint Age of blood as a limitation for transfusion: potential impact on blood inventory and availability
    Magali J Fontaine
    Department of Pathology, Stanford University School of Medicine, Stanford University Medical Center, 300 Pasteur Drive, Room H1402, M C 5626, Stanford, CA 94305 5626, USA
    Transfusion 50:2233-9. 2010
    ..Evolving concerns about storage lesions for red blood cells (RBCs) have led to ongoing trials evaluating the benefits of transfusing fresher blood to acutely ill patients...
  24. ncbi request reprint Detection, evaluation, and management of anemia in the elective surgical patient
    Lawrence T Goodnough
    Department of Pathology, Stanford University Medical Center, 300 Pasteur Drive H 1402, Stanford, CA 94305 5626, USA
    Anesth Analg 101:1858-61. 2005
    ....
  25. doi request reprint Retrospective analysis of transfusion outcomes in pregnant patients at a tertiary obstetric center
    A J Butwick
    Department of Anesthesiology MC 5640, 300 Pasteur Drive, Stanford University School ofMedicine, Stanford, California 94305, USA
    Int J Obstet Anesth 18:302-8. 2009
    ..We performed a retrospective study to review transfusion outcomes in pregnant and postpartum patients at a large obstetric center...
  26. doi request reprint Postpartum hemorrhage treated with a massive transfusion protocol at a tertiary obstetric center: a retrospective study
    M C Gutierrez
    Department of Anesthesia, Stanford University School of Medicine, Stanford, CA 94305, USA
    Int J Obstet Anesth 21:230-5. 2012
    ..The etiology of postpartum hemorrhage, transfusion outcomes and laboratory indices in obstetric cases requiring the massive transfusion protocol were retrospectively evaluated in a tertiary obstetric center...
  27. ncbi request reprint Alloimmunization to red blood cell antigens affects clinical outcomes in liver transplant patients
    Scott D Boyd
    Department of Pathology, Stanford University, and Department of Transfusion Medicine, Stanford University Hospitals and Clinics, CA 94305, USA
    Liver Transpl 13:1654-61. 2007
    ..Our findings suggest that blood transfusion and immune modulation greatly affect the survival of patients after liver transplantation...
  28. ncbi request reprint Prevalence and outcomes of anemia in rheumatoid arthritis: a systematic review of the literature
    Alisa Wilson
    Zynx Health, Beverly Hills, California 90212, USA
    Am J Med 116:50S-57S. 2004
    ..Whether improvements in QOL and/or joint symptoms occur with improvement of anemia, independent of other signs of an overall response to RA therapy, remains to be determined...
  29. ncbi request reprint The role of iron in erythropoiesis in the absence and presence of erythropoietin therapy
    Lawrence Tim Goodnough
    Department of Medicine and Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Nephrol Dial Transplant 17:14-8. 2002
    ..The availability of better tolerated i.v. iron preparations provides an ideal opportunity to study the value of iron therapy in patients with acute blood loss, particularly those undergoing rHuEPO therapy...
  30. ncbi request reprint Invited commentary
    Lawrence Tim Goodnough
    Department of Pathology and Medicine, Stanford Medical Center, 300 Pasteur Dr H 1402, Stanford, CA 94304 5626, USA
    Ann Thorac Surg 78:1554-5. 2004
  31. ncbi request reprint Transfusion medicine service policies for recombinant factor VIIa administration
    Lawrence Tim Goodnough
    Department of Medicine, Washington University School of Medicine Barnes Jewish Hospital, St Louis, Missouri, USA
    Transfusion 44:1325-31. 2004
    ..Currently, the decision on when and where to use rFVIIa for patients with uncontrolled bleeding continues to be one that must be made by individual physicians, assisted by their hospital pharmacotherapeutics and transfusion committees...
  32. doi request reprint The role of intravenous iron in anemia management and transfusion avoidance
    Michael Auerbach
    Private Practice, Baltimore, Maryland, USA
    Transfusion 48:988-1000. 2008
  33. ncbi request reprint Experiences with recombinant human factor VIIa in patients with thrombocytopenia
    Lawrence Tim Goodnough
    Department of Medicine, Washington University School of Medicine, St Louis, MO, USA
    Semin Hematol 41:25-9. 2004
    ..It is concluded that rFVIIa has a potential role in patients with thrombocytopenia and clinical hemorrhage...
  34. ncbi request reprint Patient safety and blood transfusion: new solutions
    Walter H Dzik
    Department of Hematology Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
    Transfus Med Rev 17:169-80. 2003
    ..Technology solutions will likely require integration with delivery of pharmaceuticals to be financially acceptable to hospitals...
  35. ncbi request reprint Acute normovolemic hemodilution
    Lawrence Tim Goodnough
    Division of Laboratory Medicine, Washington University School of Medicine, St Louis, MO, USA
    Vox Sang 83:211-5. 2002
  36. ncbi request reprint How we treat: management of life-threatening primary postpartum hemorrhage with a standardized massive transfusion protocol
    Matthew Burtelow
    Department of Pathology, Stanford University Medical Center, Stanford, California, USA
    Transfusion 47:1564-72. 2007
    ..The successful management of three cases of massive primary postpartum hemorrhage after the implementation of our new massive transfusion protocol in the maternal and fetal medicine service is described...