Tracy I George

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. doi Malignant or benign leukocytosis
    Tracy I George
    Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305 5627, USA
    Hematology Am Soc Hematol Educ Program 2012:475-84. 2012
  2. doi Systemic mastocytosis
    Tracy I George
    Department of Pathology, Stanford University School of Medicine, Stanford University Medical Center, 300 Pasteur Drive, Room H1501B, Stanford, CA 94305 5627, USA
    Hematol Oncol Clin North Am 25:1067-83, vii. 2011
  3. pmc Complete remission of primary plasma cell leukemia with bortezomib, doxorubicin, and dexamethasone: a case report
    Steven M Chan
    Division of Hematology, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA
    Cases J 2:121. 2009
  4. ncbi Epstein-Barr virus-associated peripheral T-cell lymphoma and hemophagocytic syndrome arising after liver transplantation: case report and review of the literature
    Tracy I George
    Department of Pathology, Stanford University School of Medicine, Stanford, California, USA
    Pediatr Blood Cancer 44:270-6. 2005
  5. pmc Low-grade B-Cell lymphomas with plasmacytic differentiation lack PAX5 gene rearrangements
    Tracy I George
    Department of Pathology, Stanford University Medical Center, 300 Pasteur Dr, Room H1501B, MC 5627, Stanford, CA 94305 5627, USA
    J Mol Diagn 7:346-51. 2005
  6. ncbi Naive and memory T cells induce different types of graft-versus-host disease
    Suparna Dutt
    Department of Medicine, Stanford University School of Medicine, CA 94305, USA
    J Immunol 179:6547-54. 2007
  7. pmc Host natural killer T cells induce an interleukin-4-dependent expansion of donor CD4+CD25+Foxp3+ T regulatory cells that protects against graft-versus-host disease
    Asha B Pillai
    Department of Medicine, Division of Immunology and Rheumatology, Stanford University School of Medicine, CA 38105, USA
    Blood 113:4458-67. 2009
  8. ncbi Fluorescence in situ hybridization investigation of cutaneous lesions in acute promyelocytic leukemia
    Joanna E Wrede
    Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305 5627, USA
    Mod Pathol 18:1569-76. 2005
  9. doi Immunophenotypic analysis of myeloperoxidase-negative leukemia cutis and blastic plasmacytoid dendritic cell neoplasm
    Danielle M P Cronin
    Department of Pathology, Stanford University, Stanford, CA 94305, USA
    Am J Clin Pathol 137:367-76. 2012
  10. doi Evaluation of the Beckman Coulter UniCel DxH 800, Beckman Coulter LH 780, and Abbott Diagnostics Cell-Dyn Sapphire hematology analyzers on adult specimens in a tertiary care hospital
    Brent T Tan
    Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA
    Am J Clin Pathol 135:939-51. 2011

Collaborators

Detail Information

Publications31

  1. doi Malignant or benign leukocytosis
    Tracy I George
    Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305 5627, USA
    Hematology Am Soc Hematol Educ Program 2012:475-84. 2012
    ..Myeloid leukemoid reactions commonly result from infections and show activated neutrophil changes on morphology; these should prompt evaluation for infection. Other causes of reactive myeloid leukocytoses are also discussed herein...
  2. doi Systemic mastocytosis
    Tracy I George
    Department of Pathology, Stanford University School of Medicine, Stanford University Medical Center, 300 Pasteur Drive, Room H1501B, Stanford, CA 94305 5627, USA
    Hematol Oncol Clin North Am 25:1067-83, vii. 2011
    ..Diagnostic pitfalls are reviewed with ancillary studies to help unmask the mast cell and exclude morphologic mimics...
  3. pmc Complete remission of primary plasma cell leukemia with bortezomib, doxorubicin, and dexamethasone: a case report
    Steven M Chan
    Division of Hematology, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA
    Cases J 2:121. 2009
    ..abstract:..
  4. ncbi Epstein-Barr virus-associated peripheral T-cell lymphoma and hemophagocytic syndrome arising after liver transplantation: case report and review of the literature
    Tracy I George
    Department of Pathology, Stanford University School of Medicine, Stanford, California, USA
    Pediatr Blood Cancer 44:270-6. 2005
    ..He presented with hemophagocytic syndrome (HPS) and active EBV infection, with positive serum titers and polymerase chain reaction (PCR) for EBV in blood, colon, and antral samples...
  5. pmc Low-grade B-Cell lymphomas with plasmacytic differentiation lack PAX5 gene rearrangements
    Tracy I George
    Department of Pathology, Stanford University Medical Center, 300 Pasteur Dr, Room H1501B, MC 5627, Stanford, CA 94305 5627, USA
    J Mol Diagn 7:346-51. 2005
    ..This study also confirms recent reports that found an absence of PAX5 rearrangements in LPL, suggesting the reassessment of PAX5 rearrangements in LPL...
  6. ncbi Naive and memory T cells induce different types of graft-versus-host disease
    Suparna Dutt
    Department of Medicine, Stanford University School of Medicine, CA 94305, USA
    J Immunol 179:6547-54. 2007
    ..Nevertheless, the expected increase in potency as compared with naive T cells was not observed due to differences in the pattern and kinetics of tissue injury...
  7. pmc Host natural killer T cells induce an interleukin-4-dependent expansion of donor CD4+CD25+Foxp3+ T regulatory cells that protects against graft-versus-host disease
    Asha B Pillai
    Department of Medicine, Division of Immunology and Rheumatology, Stanford University School of Medicine, CA 38105, USA
    Blood 113:4458-67. 2009
    ....
  8. ncbi Fluorescence in situ hybridization investigation of cutaneous lesions in acute promyelocytic leukemia
    Joanna E Wrede
    Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305 5627, USA
    Mod Pathol 18:1569-76. 2005
    ..Fluorescence in situ hybridization appears to be a robust technique to detect cutaneous manifestations of acute promyelocytic leukemia in formalin-fixed paraffin-embedded skin biopsies...
  9. doi Immunophenotypic analysis of myeloperoxidase-negative leukemia cutis and blastic plasmacytoid dendritic cell neoplasm
    Danielle M P Cronin
    Department of Pathology, Stanford University, Stanford, CA 94305, USA
    Am J Clin Pathol 137:367-76. 2012
    ..It is interesting that CD33 was not helpful; it stained 18 (78%) cases of LC and 11 cases (92%) of BPDCN. Our results indicate that a panel that includes CD4, CD56, CD123, and Tcl-1 can appropriately distinguish between these 2 entities...
  10. doi Evaluation of the Beckman Coulter UniCel DxH 800, Beckman Coulter LH 780, and Abbott Diagnostics Cell-Dyn Sapphire hematology analyzers on adult specimens in a tertiary care hospital
    Brent T Tan
    Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA
    Am J Clin Pathol 135:939-51. 2011
    ..The efficiency, sensitivity, and specificity of the DxH 800 were 77.0%, 87.1%, and 73.0%, respectively, compared with the Sapphire at 75.8%, 93.5%, and 68.8%, respectively, and LH 780 at 66.1%, 93.5%, and 55.3%, respectively...
  11. doi Hidden mastocytosis in acute myeloid leukemia with t(8;21)(q22;q22)
    Ryan C Johnson
    Dept of Pathology, Stanford University School of Medicine, 300 Pasteur Dr, MC 5324, Stanford, CA 94086 e mail
    Am J Clin Pathol 140:525-35. 2013
    ..To assess the frequency of systemic mastocytosis (SM) in a large series of acute myeloid leukemia (AML) with t(8;21)(q22;q22)...
  12. doi Discordant immunophenotypic profiles of adhesion molecules and cytokines in acute myeloid leukemia involving bone marrow and skin
    Reena Sachdev
    Department of Pathology, Stanford University Medical Center, CA 94305, USA
    Am J Clin Pathol 138:290-9. 2012
    ..The gain of CD62-L, CD29, and CD183 expression in bone marrow and skin infiltrates in leukemia cutis, relative to bone marrow infiltrates of cases without MLC, suggests a role for these markers in AML homing to skin...
  13. doi An updated approach to the diagnosis of myeloid leukemia cutis
    Danielle M P Cronin
    Department of Pathology, Stanford University, Stanford, CA 94305, USA
    Am J Clin Pathol 132:101-10. 2009
    ..Given the immunophenotypic differences between skin and bone marrow blasts, we provide an updated immunohistochemical approach to the diagnosis of myeloid leukemia cutis...
  14. doi Chromosomal aberrations in a case of synchronous extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue type and bronchogenic adenocarcinoma
    John S Cupp
    Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, UAS
    Appl Immunohistochem Mol Morphol 16:296-300. 2008
    ..The presence of differing genetic compositions suggests a biclonal environment composed of 2 distinct neoplastic processes...
  15. doi Two cases of concomitant acquired aplastic anemia and systemic mastocytosis
    Natalia Golardi
    Department of Pathology, University of New Mexico, Albuquerque, NM 87102, USA
    Hum Pathol 45:417-20. 2014
    ..However, given the clinical courses followed by our patients, the incidental identification of mast cell lesions consistent with indolent SM may be of uncertain significance in the setting of AA. ..
  16. ncbi Host NKT cells can prevent graft-versus-host disease and permit graft antitumor activity after bone marrow transplantation
    Asha B Pillai
    Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, CA 94305 5166, USA
    J Immunol 178:6242-51. 2007
    ..In conclusion, after TLI/ATS host conditioning and allogeneic bone marrow transplantation, host NKT cells can separate the proinflammatory and tumor cytolytic functions of donor T cells...
  17. ncbi Primary radiotherapy for localized orbital MALT lymphoma
    Quynh Thu Le
    Department of Radiation Oncology, Stanford University Medical Center, Stanford, CA 94305, USA
    Int J Radiat Oncol Biol Phys 52:657-63. 2002
    ..To define the natural history, prognosis, and radiocurability of localized orbital extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT)...
  18. ncbi B-cell transcription factor expression and immunoglobulin gene rearrangement frequency in acute myeloid leukemia with t(8;21)(q22;q22)
    Ryan C Johnson
    Department of Pathology, Stanford University School of Medicine, 300 Pasteur Dr, Stanford, CA 94305, USA
    Am J Clin Pathol 140:355-62. 2013
    ..1 by immunohistochemistry and expression of CD19, CD79a, CD20, and CD22 by flow cytometry immunophenotyping...
  19. doi The prognostic value of diagnosing concurrent multiple myeloma in immunoglobulin light chain amyloidosis
    Shira Dinner
    Division of Hematology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Br J Haematol 161:367-72. 2013
    ..Evaluation of bone marrow plasma cell infiltration and presence of myeloma associated end organ damage could be clinically useful for prognostication of patients with AL...
  20. doi Evaluation of the Beckman Coulter UniCel DxH 800 and Abbott Diagnostics Cell-Dyn Sapphire hematology analyzers on pediatric and neonatal specimens in a tertiary care hospital
    Brent T Tan
    Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA
    Am J Clin Pathol 135:929-38. 2011
    ..The efficiency of the DxH 800 was 78.0% vs the Sapphire at 68.1%. Both instruments showed identical sensitivity (91.1%), but the specificity for the DxH 800 (71.9%) was higher than that of the Sapphire (57.3%)...
  21. pmc Activity of the tyrosine kinase inhibitor PKC412 in a patient with mast cell leukemia with the D816V KIT mutation
    Jason Gotlib
    Department of Medicine, Division of Hematology, Stanford University, Stanford Cancer Center, 875 Blake Wilbur Dr, Rm 2327B, Stanford, CA 94305 5821, USA
    Blood 106:2865-70. 2005
    ..This case indicates that KIT tyrosine kinase inhibition is a feasible approach in SM, but single-agent clinical efficacy may be limited by clonal evolution in the advanced leukemic phase of this disease...
  22. ncbi Pathology of the myeloproliferative diseases
    Tracy I George
    Department of Pathology, Stanford University Medical Center, 300 Pasteur Drive, Room H1501B, Stanford, CA 94305 5627, USA
    Hematol Oncol Clin North Am 17:1101-27. 2003
    ..Given the overlap in morphology among these diseases, correlation with clinical, hematologic, and cytogenetic/molecular genetic findings is imperative for precise classification...
  23. doi Maternal T-cell engraftment associated with severe hemophagocytosis of the bone marrow in untreated X-linked severe combined immunodeficiency
    Christopher C Dvorak
    Division of Pediatric Stem Cell Transplantation, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA
    J Pediatr Hematol Oncol 30:396-400. 2008
    ..Hemophagocytosis was most likely owing to maternal graft-versus-host disease, as perforin-expressing CD8 T cells, presumably of maternal origin, were prominent in the bone marrow and there was no concurrent severe infection...
  24. ncbi Extranodal nonorbital indolent lymphomas of the head and neck: relationship between tumor control and radiotherapy
    Dhara MacDermed
    Department of Radiation Oncology, Stanford University Medical Center, CA 94305, USA
    Int J Radiat Oncol Biol Phys 59:788-95. 2004
    ..To review our experience managing extranodal nonorbital indolent lymphomas of the head and neck...
  25. pmc The new genetics of chronic neutrophilic leukemia and atypical CML: implications for diagnosis and treatment
    Jason Gotlib
    Division of Hematology, Department of Medicine, Stanford University School of Medicine Stanford Cancer Institute, Stanford, CA 94305 5821, USA
    Blood 122:1707-11. 2013
    ..Herein, we discuss the potential impact of these findings for the classification and treatment of these disorders. ..
  26. pmc L-selectin and beta7 integrin on donor CD4 T cells are required for the early migration to host mesenteric lymph nodes and acute colitis of graft-versus-host disease
    Suparna Dutt
    Department of Medicine, Stanford University School of Medicine, CCSR Building, Room 2215 C, Pasteur Drive, Stanford, CA 94305 5166, USA
    Blood 106:4009-15. 2005
    ..In conclusion, the combination of CD62L and beta7 integrin is required to induce acute colitis and facilitate entry of CD4+ donor T cells in the mesenteric nodes associated with lethal GVHD in allogeneic hosts...
  27. pmc Performance of BinaxNOW for diagnosis of malaria in a U.S. hospital
    Michael A DiMaio
    Department of Pathology, Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, California, USA
    J Clin Microbiol 50:2877-80. 2012
    ..These results support the judicious use of BinaxNOW in screening of individuals suspected of having malaria in areas of nonendemicity...
  28. ncbi Bone marrow biopsy involvement by non-Hodgkin's lymphoma: frequency of lymphoma types, patterns, blood involvement, and discordance with other sites in 450 specimens
    Daniel A Arber
    Department of Pathology, Stanford University Medical Center, Stanford, CA 94305, USA
    Am J Surg Pathol 29:1549-57. 2005
    ....
  29. ncbi Precursor B-cell acute lymphoblastic leukemia presenting with hemophagocytic lymphohistiocytosis
    MAUREEN M O'BRIEN
    Department of Pediatrics, Stanford University School of Medicine, Palo Alto, California, USA
    Pediatr Blood Cancer 50:381-3. 2008
    ..We report three cases of HLH associated with B-ALL and review 17 cases of ALL-associated HLH previously reported in the literature...
  30. ncbi Bone marrow metastases: a survey of nonhematologic metastases with immunohistochemical study of metastatic carcinomas
    Chandra Krishnan
    Department of Pathology, Stanford University, 300 Pasteur Drive, Lane 325, Stanford, CA 94305 5324, USA
    Appl Immunohistochem Mol Morphol 15:1-7. 2007
    ..Overall, the immunohistochemical characterization of metastatic carcinomas to the bone marrow show good correlation with the established staining pattern of the primary tumors...
  31. ncbi Lack of human herpesvirus 8 and Epstein-Barr virus in Kikuchi's histiocytic necrotizing lymphadenitis
    Tracy I George
    Department of Pathology, Stanford University Medical Center, CA 94305, USA
    Hum Pathol 34:130-5. 2003
    ..These findings suggest that HHV 8 and EBV do not play causative roles in Kikuchi's histiocytic necrotizing lymphadenitis...