Stephan Gehrke

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression
    Stephan Gehrke
    Department of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA
    Nature 466:637-41. 2010
  2. pmc Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin
    Yufeng Yang
    Department of Pathology and Geriatric Research, Education and Clinical Center Veterans Affairs Palo Alto Health Care System, Stanford University School of Medicine, Palo Alto, CA 94304, USA
    Proc Natl Acad Sci U S A 103:10793-8. 2006
  3. pmc Neuroprotective effects of compounds with antioxidant and anti-inflammatory properties in a Drosophila model of Parkinson's disease
    Katharina Faust
    Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA
    BMC Neurosci 10:109. 2009
  4. ncbi The synaptic function of LRRK2
    Seongsoo Lee
    Department of Pathology, Stanford University School of Medicine, R270 Edwards Building, Stanford, CA 94305, U S A
    Biochem Soc Trans 40:1047-51. 2012
  5. pmc Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling
    Yufeng Yang
    Department of Pathology, Stanford University School of Medicine, and Geriatric Research, Education and Clinical Center Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304, USA
    Proc Natl Acad Sci U S A 102:13670-5. 2005

Collaborators

Detail Information

Publications5

  1. pmc Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression
    Stephan Gehrke
    Department of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA
    Nature 466:637-41. 2010
    ..Our results implicate deregulated synthesis of E2F1/DP caused by the miRNA pathway impairment as a key event in LRRK2 pathogenesis and suggest novel miRNA-based therapeutic strategies...
  2. pmc Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin
    Yufeng Yang
    Department of Pathology and Geriatric Research, Education and Clinical Center Veterans Affairs Palo Alto Health Care System, Stanford University School of Medicine, Palo Alto, CA 94304, USA
    Proc Natl Acad Sci U S A 103:10793-8. 2006
    ..Together, these results implicate Pink1 and Parkin in a common pathway that regulates mitochondrial physiology and cell survival in Drosophila...
  3. pmc Neuroprotective effects of compounds with antioxidant and anti-inflammatory properties in a Drosophila model of Parkinson's disease
    Katharina Faust
    Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA
    BMC Neurosci 10:109. 2009
    ....
  4. ncbi The synaptic function of LRRK2
    Seongsoo Lee
    Department of Pathology, Stanford University School of Medicine, R270 Edwards Building, Stanford, CA 94305, U S A
    Biochem Soc Trans 40:1047-51. 2012
    ....
  5. pmc Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling
    Yufeng Yang
    Department of Pathology, Stanford University School of Medicine, and Geriatric Research, Education and Clinical Center Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304, USA
    Proc Natl Acad Sci U S A 102:13670-5. 2005
    ..Manipulation of PI3K/Akt signaling may therefore offer therapeutic benefits for the treatment of PD...