Robert Fisher

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. ncbi Gamma oscillation underlies hyperthermia-induced epileptiform-like spikes in immature rat hippocampal slices
    J Wu
    Division of Neurology, Barrow Neurological Institute, St Joseph s Hospital and Medical Center, Phoenix, AZ 85013, USA
    BMC Neurosci 2:18. 2001
  2. ncbi Potential new methods for antiepileptic drug delivery
    Robert S Fisher
    Stanford Comprehensive Epilepsy Center, Stanford University Medical Center, Stanford, California 94305 5235, USA
    CNS Drugs 16:579-93. 2002
  3. ncbi Photic- and pattern-induced seizures: a review for the Epilepsy Foundation of America Working Group
    Robert S Fisher
    Department of Neurology and Neurological Sciences, Stanford Medical Center, Stanford, California 94305 5235, USA
    Epilepsia 46:1426-41. 2005
  4. ncbi New routes for delivery of anti-epileptic medications
    Robert S Fisher
    Stanford Comprehensive Epilepsy Center, Stanford University Medical Center, 300 Pasteur Drive, Stanford, California 94305 5235, USA
    Acta Neurol Taiwan 15:225-31. 2006
  5. ncbi Electrical stimulation of the anterior nucleus of thalamus for treatment of refractory epilepsy
    Robert Fisher
    Department of Neurology, Stanford University, Stanford, California 94305 5235, USA
    Epilepsia 51:899-908. 2010
  6. ncbi Definition of the postictal state: when does it start and end?
    Robert S Fisher
    Department of Neurology and Neurological Science, Stanford University School of Medicine, Stanford, CA 94305 5235, USA
    Epilepsy Behav 19:100-4. 2010
  7. ncbi Selective changes in thalamic and cortical GABAA receptor subunits in a model of acquired absence epilepsy in the rat
    Huifang Li
    Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Room A343, Stanford Medical Center, 300 Pasteur Drive, Stanford, CA 94305 5235, USA
    Neuropharmacology 51:121-8. 2006
  8. ncbi Gender and age differences in expression of GABAA receptor subunits in rat somatosensory thalamus and cortex in an absence epilepsy model
    Huifang Li
    Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Room A343, Stanford Medical Center, 300 Pasteur Drive, Stanford, CA 94305 5235, USA
    Neurobiol Dis 25:623-30. 2007
  9. ncbi Debate: When does a seizure imply epilepsy?
    Robert S Fisher
    Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, USA
    Epilepsia 49:7-12. 2008
  10. ncbi Epileptic seizures and epilepsy: definitions proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE)
    Robert S Fisher
    Stanford University Medical Center, Department of Neurology, Stanford, California 94305 5235, USA
    Epilepsia 46:470-2. 2005

Research Grants

  1. PILOT TRIAL OF THALAMIC STIMULATION FOR EPILEPSY
    Robert Fisher; Fiscal Year: 2001

Collaborators

Detail Information

Publications28

  1. ncbi Gamma oscillation underlies hyperthermia-induced epileptiform-like spikes in immature rat hippocampal slices
    J Wu
    Division of Neurology, Barrow Neurological Institute, St Joseph s Hospital and Medical Center, Phoenix, AZ 85013, USA
    BMC Neurosci 2:18. 2001
    ..This may serve as an in vitro model of febrile seizures...
  2. ncbi Potential new methods for antiepileptic drug delivery
    Robert S Fisher
    Stanford Comprehensive Epilepsy Center, Stanford University Medical Center, Stanford, California 94305 5235, USA
    CNS Drugs 16:579-93. 2002
    ..New delivery systems should significantly improve the therapeutic/toxic ratio of AEDs...
  3. ncbi Photic- and pattern-induced seizures: a review for the Epilepsy Foundation of America Working Group
    Robert S Fisher
    Department of Neurology and Neurological Sciences, Stanford Medical Center, Stanford, California 94305 5235, USA
    Epilepsia 46:1426-41. 2005
    ..This report summarizes background material presented to a consensus conference on visually provoked seizures, convened by the Epilepsy Foundation of America...
  4. ncbi New routes for delivery of anti-epileptic medications
    Robert S Fisher
    Stanford Comprehensive Epilepsy Center, Stanford University Medical Center, 300 Pasteur Drive, Stanford, California 94305 5235, USA
    Acta Neurol Taiwan 15:225-31. 2006
    ..Lastly, we discuss future prospects for the use of transplanted cells and genes as potential vehicles for local delivery of renewable anti-epileptic regimen...
  5. ncbi Electrical stimulation of the anterior nucleus of thalamus for treatment of refractory epilepsy
    Robert Fisher
    Department of Neurology, Stanford University, Stanford, California 94305 5235, USA
    Epilepsia 51:899-908. 2010
    ..We report a multicenter, double-blind, randomized trial of bilateral stimulation of the anterior nuclei of the thalamus for localization-related epilepsy...
  6. ncbi Definition of the postictal state: when does it start and end?
    Robert S Fisher
    Department of Neurology and Neurological Science, Stanford University School of Medicine, Stanford, CA 94305 5235, USA
    Epilepsy Behav 19:100-4. 2010
    ..Except where boundaries are clear, it is better to describe a sequence of behaviors and electroencephalographic changes, without labeling arbitrary stages as being ictal or postictal...
  7. ncbi Selective changes in thalamic and cortical GABAA receptor subunits in a model of acquired absence epilepsy in the rat
    Huifang Li
    Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Room A343, Stanford Medical Center, 300 Pasteur Drive, Stanford, CA 94305 5235, USA
    Neuropharmacology 51:121-8. 2006
    ..Selective reductions in GABA(A) receptor subunits in thalamus may play a role in pathophysiology of absence epilepsy...
  8. ncbi Gender and age differences in expression of GABAA receptor subunits in rat somatosensory thalamus and cortex in an absence epilepsy model
    Huifang Li
    Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Room A343, Stanford Medical Center, 300 Pasteur Drive, Stanford, CA 94305 5235, USA
    Neurobiol Dis 25:623-30. 2007
    ..The findings suggest a mechanism for the higher prevalence of absence epilepsy in female patients...
  9. ncbi Debate: When does a seizure imply epilepsy?
    Robert S Fisher
    Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, USA
    Epilepsia 49:7-12. 2008
    ..Future clinical and epidemiologic evidence would allow refinements of the operational definitions...
  10. ncbi Epileptic seizures and epilepsy: definitions proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE)
    Robert S Fisher
    Stanford University Medical Center, Department of Neurology, Stanford, California 94305 5235, USA
    Epilepsia 46:470-2. 2005
    ..The definition of epilepsy requires the occurrence of at least one epileptic seizure...
  11. ncbi Focally injected adenosine prevents seizures in the rat
    David J Anschel
    Comprehensive Epilepsy Center, Department of Neurology, Stanford University Medical Center, Stanford, CA 94305-5235, USA
    Exp Neurol 190:544-7. 2004
    ..0001). This study demonstrates effectiveness and feasibility in a model system using intracranial injection of adenosine to prevent epileptiform events...
  12. ncbi A blinded pilot study of artwork in a comprehensive epilepsy center population
    David J Anschel
    Department of Neurology, Stanford Comprehensive Epilepsy Center, 300 Pasteur Drive, Room 43160, Stanford, CA 94305 6648, USA
    Epilepsy Behav 6:196-202. 2005
    ..In addition to giving some insight into the neurological functioning of these subjects, this pilot study provides a basis for the future development of diagnostic tests to be used within this patient group...
  13. ncbi Diazepam prophylaxis for bicuculline-induced seizures: a rat dose-response model
    David J Anschel
    Department of Neurology, Stanford Comprehensive Epilepsy Center, Stanford University Medical Center, Stanford, CA 94305 5235, USA
    Neurosci Lett 356:66-8. 2004
    ..Numbers of ictal events (seizure) and latency to the first event were reduced by prophylactic DZP. The study establishes a protocol for testing of intracranially-injected drugs to prevent focal seizures...
  14. ncbi Therapeutic brain stimulation for epilepsy
    Juliana Lockman
    Department of Neurology and Neurological Sciences, Room A343, 300 Pasteur Drive, Stanford University School of Medicine, Stanford, CA 94305 5235, USA
    Neurol Clin 27:1031-40. 2009
    ..DBS is palliative rather than curative, but experience suggests that this relatively new therapy may be of benefit to some people with otherwise untreatable epilepsy...
  15. ncbi Abnormal benzodiazepine and zinc modulation of GABAA receptors in an acquired absence epilepsy model
    Jie Wu
    Division of Neurology, Barrow Neurological Institute, St Joseph s Hospital and Medical Center, 350 West Thomas Road, Phoenix, AZ 85013 4496, USA
    Brain Res 1013:230-40. 2004
    ..The present results are also consistent with recent findings that mutation of the gamma2 subunit of the GABAA receptor changes benzodiazepine modulation in families with generalized epilepsy syndromes...
  16. ncbi Cooling abolishes neuronal network synchronization in rat hippocampal slices
    Sam P Javedan
    Division of Neurological Surgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona 85013, USA
    Epilepsia 43:574-80. 2002
    ..Cooling also suppresses transition from gamma oscillation to ictal bursting at higher stimulus intensities. These findings suggest that cooling may disrupt network synchrony necessary for epileptiform activity...
  17. ncbi Neurostimulation for epilepsy, including a pilot study of anterior nucleus stimulation
    Nina M Graves
    Medtronic, Inc, Minneapolis, Minnesota, USA
    Clin Neurosurg 52:127-34. 2005
  18. ncbi Photic- and pattern-induced seizures: expert consensus of the Epilepsy Foundation of America Working Group
    Graham Harding
    Clinical Neurophysiology Unit, Aston University, Birmingham, UK
    Epilepsia 46:1423-5. 2005
    ..CONCLUSIONS: A consensus view of stimuli likely to provoke visually evoked seizures can be developed...
  19. ncbi Intraventricular administration of gabapentin in the rat increases flurothyl seizure threshold
    Joseph Oommen
    Department of Neurology, University of Texas at Galveston, United States
    Neurosci Lett 417:308-11. 2007
    ..We investigated efficacy of prolonged intraventricular gabapentin (GBP) infusion in the rat flurothyl epilepsy model...
  20. ncbi Seizure-related motor vehicle crashes in Arizona before and after reducing the driving restriction from 12 to 3 months
    Joseph F Drazkowski
    Department of Neurology, Mayo Clinic, Scottsdale, Ariz 85259, USA
    Mayo Clin Proc 78:819-25. 2003
    ..To evaluate whether changing the seizure-free interval in Arizona from 12 months to 3 months affected the number of seizure-related motor vehicle crashes...
  21. ncbi Sensitivity and specificity of video alone versus electroencephalography alone for the diagnosis of partial seizures
    David K Chen
    Peter Kellaway Section of Neurophysiology, Department of Neurology, Baylor College of Medicine, Houston, TX, USA
    Epilepsy Behav 13:115-8. 2008
    ..Home video recordings may represent a useful screening tool for a subset of patients with neurobehavioral events of unclear etiology...
  22. ncbi Tonic and phasic pyloric activity in response to CCK-octapeptide
    Frank K Friedenberg
    Department of Medicine, Section of Gastroenterology, Temple University Hospital, Temple University School of Medicine, 3401 N Broad Street, Philadelphia, PA 19140, USA
    Dig Dis Sci 53:905-11. 2008
    ..The purpose of this study was to determine whether a high-resolution solid-state catheter system could detect regional pressure changes within the antrum and pylorus in response to CCK-octapeptide...
  23. ncbi Intracellular energy failure does not underlie hyperthermic spreading depressions in immature rat hippocampal slice
    Jie Wu
    Neurology, Barrow Neurological Institute, St Joseph s Hospital and Medical Center, 350 West Thomas Road, Phoenix, AZ 85013 4496, USA
    Brain Res 987:240-3. 2003
    ..This study suggests that HSD is not be mediated by depletion of intracellular ATP during hyperthermia...
  24. ncbi Conversion disorder
    Cynthia M Stonnington
    Division of Adult Psychiatry, Mayo Clinic, 13400 East Shea Blvd, Scottsdale, AZ 85259, USA
    Am J Psychiatry 163:1510-7. 2006
  25. ncbi Brain stimulation for epilepsy
    William H Theodore
    Clinical Epilepsy Section, National Institute of Neurological Diseases and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    Lancet Neurol 3:111-8. 2004
    ..Future investigations are likely to study extrathalamic sites of stimulation, and effects of stimulation contingent upon detection of or prediction of EEG patterns of epileptiform activity...
  26. ncbi Measuring the effects of antiepileptic medications on balance in older people
    Terry D Fife
    Department of Neurology, Barrow Neurological Institute, Phoenix, AZ 85013, USA
    Epilepsy Res 70:103-9. 2006
    ..This study was undertaken to prospectively compare quantitative measures of balance in older people taking carbamazepine, gabapentin and lamotrigine...
  27. ncbi Electrical stimulation of the anterior nucleus of the thalamus for the treatment of intractable epilepsy
    John F Kerrigan
    Department of Neurology, Barrow Neurological Institute, St Joseph s Hospital and Medical Center, Phoenix, Arizona, USA
    Epilepsia 45:346-54. 2004
    ....
  28. ncbi Use of serum prolactin in diagnosing epileptic seizures: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology
    David K Chen
    Stanford University, Palo Alto, CA, USA
    Neurology 65:668-75. 2005
    ..Serum prolactin assay does not distinguish epileptic seizures from syncope (Level B). The use of serum PRL assay has not been established in the evaluation of status epilepticus, repetitive seizures, and neonatal seizures (Level U)...

Research Grants1

  1. PILOT TRIAL OF THALAMIC STIMULATION FOR EPILEPSY
    Robert Fisher; Fiscal Year: 2001
    ..A consortium of centers experienced in epilepsy research will collaborate on this project, which will move brain stimulation for epilepsy into the realm of a testable new therapy for intractable seizures. ..