MICHAEL FAYER

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. doi request reprint Water in a crowd
    Michael D Fayer
    Department of Chemistry, Stanford University, Stanford, California, USA
    Physiology (Bethesda) 26:381-92. 2011
  2. doi request reprint Analysis of water in confined geometries and at interfaces
    Michael D Fayer
    Department of Chemistry, Stanford University, California 94305, USA
    Annu Rev Anal Chem (Palo Alto Calif) 3:89-107. 2010
  3. pmc Water dynamics in salt solutions studied with ultrafast two-dimensional infrared (2D IR) vibrational echo spectroscopy
    Michael D Fayer
    Department of Chemistry, Stanford University, Stanford, California 94305, USA
    Acc Chem Res 42:1210-9. 2009
  4. doi request reprint Dynamics of liquids, molecules, and proteins measured with ultrafast 2D IR vibrational echo chemical exchange spectroscopy
    M D Fayer
    Department of Chemistry, Stanford University, Stanford, California 94305, USA
    Annu Rev Phys Chem 60:21-38. 2009
  5. ncbi request reprint Orientational dynamics of water confined on a nanometer length scale in reverse micelles
    Howe Siang Tan
    Department of Chemistry, Stanford University, California 94305, USA
    J Chem Phys 122:174501. 2005
  6. ncbi request reprint Dynamics of water confined on a nanometer length scale in reverse micelles: ultrafast infrared vibrational echo spectroscopy
    Howe Siang Tan
    Department of Chemistry, Stanford University, Stanford, California 94305, USA
    Phys Rev Lett 94:057405. 2005
  7. pmc Confinement or the nature of the interface? Dynamics of nanoscopic water
    David E Moilanen
    Department of Chemistry, Stanford University, Palo Alto, California 94305, USA
    J Am Chem Soc 129:14311-8. 2007
  8. ncbi request reprint Fast protein dynamics probed with infrared vibrational echo experiments
    M D Fayer
    Department of Chemistry, Stanford University, Stanford, California 94305, USA
    Annu Rev Phys Chem 52:315-56. 2001
  9. pmc Viscosity-dependent protein dynamics
    Ilya J Finkelstein
    Department of Chemistry, Stanford University, Stanford, California, USA
    Biophys J 92:3652-62. 2007
  10. pmc Fifth-order contributions to ultrafast spectrally resolved vibrational echoes: heme-CO proteins
    Ilya J Finkelstein
    Department of Chemistry, Stanford University, Stanford, California 94305, USA
    J Chem Phys 121:877-85. 2004

Collaborators

  • Nancy E Levinger
  • STEVEN BOXER
  • Biman Bagchi
  • Ryo Akiyama
  • David E Moilanen
  • Ilya J Finkelstein
  • Emily E Fenn
  • Kyungwon Kwak
  • Brian L McClain
  • Aaron M Massari
  • Howe Siang Tan
  • D B Spry
  • Ivan R Piletic
  • Daniel E Rosenfeld
  • Daryl Wong
  • John B Asbury
  • Seongheun Kim
  • Sungnam Park
  • Roger F Loring
  • Kusai A Merchant
  • Lisa N Silverman
  • Junrong Zheng
  • Kara L Bren
  • Ksenija Glusac
  • J L Skinner
  • Anne Goj
  • Alexei Goun
  • Tobias Steinel
  • K A Merchant
  • Zsolt Gengeliczki
  • Daryl B Wong
  • Yu Shan Lin
  • Sarah E J Bowman
  • Jean K Chung
  • Haruto Ishikawa
  • K Glusac
  • A Goun
  • Xin Wen
  • Ruth E Riter
  • C P Lawrence
  • S A Corcelli
  • W G Noid
  • C Stromberg
  • I R Piletic
  • K J Gaffney
  • Alexi Goun
  • D E Thompson

Detail Information

Publications32

  1. doi request reprint Water in a crowd
    Michael D Fayer
    Department of Chemistry, Stanford University, Stanford, California, USA
    Physiology (Bethesda) 26:381-92. 2011
    ..Here, the results of ultrafast infrared experiments are described that shed light on the influences of nanoconfinement, interfaces, ions, and organic molecules on water hydrogen bond dynamics...
  2. doi request reprint Analysis of water in confined geometries and at interfaces
    Michael D Fayer
    Department of Chemistry, Stanford University, California 94305, USA
    Annu Rev Anal Chem (Palo Alto Calif) 3:89-107. 2010
    ..These experiments can be applied to water in reverse micelles (spherical nanopools). The results provide quantitative determination of the dynamics of water as a function of the size and nature of the confining structure...
  3. pmc Water dynamics in salt solutions studied with ultrafast two-dimensional infrared (2D IR) vibrational echo spectroscopy
    Michael D Fayer
    Department of Chemistry, Stanford University, Stanford, California 94305, USA
    Acc Chem Res 42:1210-9. 2009
    ..The results demonstrate that water interacting with ions has slower hydrogen-bond dynamics than pure water, but the slowing is a factor of 3 or 4 rather than orders of magnitude...
  4. doi request reprint Dynamics of liquids, molecules, and proteins measured with ultrafast 2D IR vibrational echo chemical exchange spectroscopy
    M D Fayer
    Department of Chemistry, Stanford University, Stanford, California 94305, USA
    Annu Rev Phys Chem 60:21-38. 2009
    ..The results are used to obtain an approximate isomerization rate for ethane. Finally, the time dependence of a well-defined single structural transformation of a protein is measured...
  5. ncbi request reprint Orientational dynamics of water confined on a nanometer length scale in reverse micelles
    Howe Siang Tan
    Department of Chemistry, Stanford University, California 94305, USA
    J Chem Phys 122:174501. 2005
    ..The angle over which the inertial orientational motion occurs is determined. The results are in semiquantitative agreement with the molecular-dynamics simulations...
  6. ncbi request reprint Dynamics of water confined on a nanometer length scale in reverse micelles: ultrafast infrared vibrational echo spectroscopy
    Howe Siang Tan
    Department of Chemistry, Stanford University, Stanford, California 94305, USA
    Phys Rev Lett 94:057405. 2005
    ..The fastest dynamics (approximately 50 fs) is more similar to bulk water, while the slowest time scale dynamics is much slower than water, and, in analogy to bulk water, reflects the making and breaking of hydrogen bonds...
  7. pmc Confinement or the nature of the interface? Dynamics of nanoscopic water
    David E Moilanen
    Department of Chemistry, Stanford University, Palo Alto, California 94305, USA
    J Am Chem Soc 129:14311-8. 2007
    ..The results demonstrate that confinement by an interface to form a nanoscopic water pool is a primary factor governing the dynamics of nanoscopic water rather than the presence of charged groups at the interface...
  8. ncbi request reprint Fast protein dynamics probed with infrared vibrational echo experiments
    M D Fayer
    Department of Chemistry, Stanford University, Stanford, California 94305, USA
    Annu Rev Phys Chem 52:315-56. 2001
    ..The dynamic electric field-coupling mechanism is tested by observing differences in the temperature dependence of the pure dephasing of Mb-CO mutations...
  9. pmc Viscosity-dependent protein dynamics
    Ilya J Finkelstein
    Department of Chemistry, Stanford University, Stanford, California, USA
    Biophys J 92:3652-62. 2007
    ..A calibration method based on the near-infrared spectrum of water overtones was constructed to accurately determine the viscosity of small volumes of protein solutions...
  10. pmc Fifth-order contributions to ultrafast spectrally resolved vibrational echoes: heme-CO proteins
    Ilya J Finkelstein
    Department of Chemistry, Stanford University, Stanford, California 94305, USA
    J Chem Phys 121:877-85. 2004
    ..Finally, it is shown that the anharmonic oscillations in vibrational echo data of Hb-CO that previous work had attributed strictly to fifth order effects arise even without fifth order contributions...
  11. pmc Ion-water hydrogen-bond switching observed with 2D IR vibrational echo chemical exchange spectroscopy
    David E Moilanen
    Department of Chemistry, Stanford University, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 106:375-80. 2009
    ..Pump-probe measurements of the orientational relaxation rates and vibrational lifetimes are used in the CES data analysis. The pump-probe measurements are shown to have the correct functional form for a system undergoing exchange...
  12. ncbi request reprint Dynamics of nanoscopic water: vibrational echo and infrared pump-probe studies of reverse micelles
    Ivan R Piletic
    Department of Chemistry, Stanford University, Stanford, California 94305, USA
    J Phys Chem B 109:21273-84. 2005
    ..The vibrational echo data for the smallest reverse micelle displays a dependence on the detection wavelength, which may indicate that multiple ensembles of water molecules are being observed...
  13. pmc Myoglobin-CO substate structures and dynamics: multidimensional vibrational echoes and molecular dynamics simulations
    Kusai A Merchant
    Department of Chemistry, Stanford University, Stanford, California 94305, USA
    J Am Chem Soc 125:13804-18. 2003
    ..Dephasing in the A(1) state is controlled by His64 on femtosecond time scales, and by the rest of the protein and the water solvent on longer time scales...
  14. pmc Dynamics around solutes and solute-solvent complexes in mixed solvents
    Kyungwon Kwak
    Department of Chemistry, Stanford University, Stanford CA 94305, USA
    Proc Natl Acad Sci U S A 104:14221-6. 2007
    ..The experimental results and recent MD simulations indicate that the solvent structure around the solute may be different from the mixed solvent's mole fraction...
  15. pmc Dynamics of hemoglobin in human erythrocytes and in solution: influence of viscosity studied by ultrafast vibrational echo experiments
    Brian L McClain
    Department of Chemistry, Stanford University, Stanford, California 94305, USA
    J Am Chem Soc 126:15702-10. 2004
    ....
  16. ncbi request reprint Dynamics of water probed with vibrational echo correlation spectroscopy
    John B Asbury
    Department of Chemistry, Stanford University, Stanford, California 94305, USA
    J Chem Phys 121:12431-46. 2004
    ..The SPC-FQ derived FTCF is much closer to the experimental results than previously tested nonpolarizable water models which are also presented for comparison...
  17. pmc Water dynamics at neutral and ionic interfaces
    Emily E Fenn
    Department of Chemistry, Stanford University, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 106:15243-8. 2009
    ....
  18. doi request reprint Geometry and nanolength scales versus interface interactions: water dynamics in AOT lamellar structures and reverse micelles
    David E Moilanen
    Department of Chemistry, Stanford University, Stanford, California 94305, USA
    J Am Chem Soc 131:8318-28. 2009
    ....
  19. pmc Water dynamics at the interface in AOT reverse micelles
    David E Moilanen
    Department of Chemistry, Stanford University, California 94305, USA
    J Phys Chem B 113:8560-8. 2009
    ..The orientational relaxation of interfacial water molecules occurs in 18 +/- 3 ps, in contrast to the bulk water value of 2.6 ps...
  20. ncbi request reprint Hydrogen bond dynamics probed with ultrafast infrared heterodyne-detected multidimensional vibrational stimulated echoes
    John B Asbury
    Department of Chemistry, Stanford University, Stanford, California 94305, USA
    Phys Rev Lett 91:237402. 2003
    ....
  21. pmc Hydrogen bond migration between molecular sites observed with ultrafast 2D IR chemical exchange spectroscopy
    Daniel E Rosenfeld
    Department of Chemistry, Stanford University, Stanford, California 94305, USA
    J Phys Chem B 114:2383-9. 2010
    ..The observation of direct hydrogen bond migration can have implications for macromolecular systems...
  22. doi request reprint Water dynamics--the effects of ions and nanoconfinement
    Sungnam Park
    Department of Chemistry Stanford University, Stanford, California 94305, USA
    J Phys Chem B 112:5279-90. 2008
    ....
  23. ncbi request reprint Two-dimensional time-frequency ultrafast infrared vibrational echo spectroscopy
    K A Merchant
    Department of Chemistry, Stanford University, Stanford, California 94305, USA
    Phys Rev Lett 86:3899-902. 2001
    ..A new explanation is given for these "anharmonic" oscillations. Calculations show that spectral resolution enables the 0-1 and 1-2 dephasing to be measured independently...
  24. pmc Substrate binding and protein conformational dynamics measured by 2D-IR vibrational echo spectroscopy
    Ilya J Finkelstein
    Department of Chemistry, Stanford University, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 104:2637-42. 2007
    ..It is suggested that dynamic quenching caused by substrate binding can cause the protein to be locked into a conformation suitable for downstream steps in the enzymatic cycle of HRP...
  25. ncbi request reprint Photoinduced electron transfer and geminate recombination in the group head region of micelles
    Ksenija Glusac
    Department of Chemistry, Stanford University, Stanford, California 94305, USA
    J Chem Phys 125:054712. 2006
    ..The theory includes important aspects of the topology of the micelle and the diffusion of the donor-acceptors in the micelle head group region. A semiquantitative but nonquantitative agreement between theory and experiments is achieved...
  26. ncbi request reprint Proton transport and the water environment in nafion fuel cell membranes and AOT reverse micelles
    D B Spry
    Department of Chemistry, Stanford University, Stanford, CA 94305, USA
    J Am Chem Soc 129:8122-30. 2007
    ..The effective size of the Nafion water channels at various hydration levels are estimated by the known size of the AOT reverse micelles that display the corresponding proton-transfer kinetics and orientational relaxation...
  27. pmc Native and unfolded cytochrome c--comparison of dynamics using 2D-IR vibrational echo spectroscopy
    Seongheun Kim
    Department of Chemistry, Stanford University, Stanford, California 94305, USA
    J Phys Chem B 112:10054-63. 2008
    ..The results suggest the denatured protein may be in a glassy-like state involving hydrophobic collapse around the heme...
  28. doi request reprint Charge transfer in photoacids observed by stark spectroscopy
    Lisa N Silverman
    Department of Chemistry, Stanford University, Stanford, California 94305, USA
    J Phys Chem A 112:10244-9. 2008
    ..Conversely, for the cationic (ammonium) photoacid studied, photoexcitation of a particular electronic state results in much smaller charge transfer for the protonated state than for the deprotonated state...
  29. ncbi request reprint Ultrafast dynamics of myoglobin without the distal histidine: stimulated vibrational echo experiments and molecular dynamics simulations
    Ilya J Finkelstein
    Department of Chemistry, Stanford University, Stanford, California 94305, USA
    J Phys Chem B 109:16959-66. 2005
    ..However, vibrational echoes calculated for H64V do not show the quantitative agreement with measurements demonstrated previously for the native protein...
  30. ncbi request reprint The influence of aqueous versus glassy solvents on protein dynamics: vibrational echo experiments and molecular dynamics simulations
    Aaron M Massari
    Department of Chemistry, Stanford University, Stanford, CA 94305, USA
    J Am Chem Soc 127:14279-89. 2005
    ....
  31. pmc Hydrogen bond lifetimes and energetics for solute/solvent complexes studied with 2D-IR vibrational echo spectroscopy
    Junrong Zheng
    Department of Chemistry, Stanford University, Stanford, California 94305, USA
    J Am Chem Soc 129:4328-35. 2007
    ..The correlation can be described with an equation similar to the Arrhenius equation. The results are discussed in terms of transition state theory...
  32. pmc Water inertial reorientation: hydrogen bond strength and the angular potential
    David E Moilanen
    Department of Chemistry, Stanford University, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 105:5295-300. 2008
    ....

Research Grants11

  1. Biodynamics: Vibrational Echo Correlation Spectroscopy
    MICHAEL FAYER; Fiscal Year: 2007
    ..In addition, water-protein dynamical interactions and water-protein hydrogen bond dynamics in nanoscopic water environments will be examined. ..
  2. PROTEIN DYNAMICS AND INTERACTIONS: VIBRATIONAL ECHOES
    MICHAEL FAYER; Fiscal Year: 2003
    ..abstract_text> ..
  3. Protein, Enzyme, and Biological Water Dynamics: 2D Vibrational Echo Spectroscopy
    Michael D Fayer; Fiscal Year: 2010
    ..The methodology builds on previous successful applications and developments of state-of-the-art ultrafast infrared laser experiments. ..