Research Topics
| Chuong B DoSummaryAffiliation: Stanford University Country: USA Publications
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Detail Information
Publications
CONTRAfold: RNA secondary structure prediction without physics-based modelsChuong B Do
Computer Science Department, Stanford University, Stanford, CA 94305, USA
Bioinformatics 22:e90-8. 2006....
A max-margin model for efficient simultaneous alignment and folding of RNA sequencesChuong B Do
Computer Science Department, Stanford University, Stanford, CA 94305, USA
Bioinformatics 24:i68-76. 2008..RAF's fast sparse dynamic programming, in turn, serves as the inference engine within a discriminative machine learning algorithm for parameter estimation...
Glocal alignment: finding rearrangements during alignmentMichael Brudno
Department of Computer Science, Stanford University, Stanford, CA 94305, USA
Bioinformatics 19:i54-62. 2003..From the alignments we conclude that about 9% of human/mouse homology may be attributed to small rearrangements, 63% of which are duplications...
CONTRAST: a discriminative, phylogeny-free approach to multiple informant de novo gene predictionSamuel S Gross
Computer Science Department, Stanford University, Stanford, CA, USA
Genome Biol 8:R269. 2007..CONTRAST predicts exact coding region structures for 65% more human genes than the previous state-of-the-art method, misses 46% fewer exons and displays comparable gains in specificity...
A Classifier-based approach to identify genetic similarities between diseasesMarc A Schaub
Department of Computer Science, Stanford University, Stanford, CA 94305, USA
Bioinformatics 25:i21-9. 2009..We show that this approach identifies the known genetic similarity between type 1 diabetes and rheumatoid arthritis, and identifies a new putative similarity between bipolar disease and hypertension...
What is the expectation maximization algorithm?Chuong B Do
Computer Science Department, Stanford University, 318 Campus Drive, Stanford, California 94305 5428, USA
Nat Biotechnol 26:897-9. 2008
Protein multiple sequence alignmentChuong B Do
Computer Science Department, Stanford University, Stanford, CA, USA
Methods Mol Biol 484:379-413. 2008..In this chapter, we review state-of-the-art protein sequence alignment and provide practical advice for users of alignment tools...
Automatic parameter learning for multiple local network alignmentJason Flannick
Department of Computer Science, Stanford University, Stanford, CA 94305, USA
J Comput Biol 16:1001-22. 2009..We show that, on each of these datasets, Graemlin 2.0 has higher sensitivity and specificity than existing network aligners. Graemlin 2.0 is available under the GNU public license at http://graemlin.stanford.edu ...
Evidence for intelligent (algorithm) designBalaji S Srinivasan
Department of Electrical Engineering, Stanford University, Stanford, CA 94305, USA
Genome Biol 7:322. 2006..A report on the 10th annual Research in Computational Molecular Biology (RECOMB) Conference, Venice, Italy, 2-5 April 2006...
ProbCons: Probabilistic consistency-based multiple sequence alignmentChuong B Do
Department of Computer Science, Stanford University, Stanford, California 94305, USA
Genome Res 15:330-40. 2005..On the BAliBASE, SABmark, and PREFAB benchmark alignment databases, ProbCons achieves statistically significant improvement over other leading methods while maintaining practical speed. ProbCons is publicly available as a Web resource...
Effect of genetic divergence in identifying ancestral origin using HAPAAAndreas Sundquist
Department of Computer Science, Stanford University, Stanford, California 94305, USA
Genome Res 18:676-82. 2008..Using HAPAA, we explore the limits of ancestry inference in closely related populations...
LAGAN and Multi-LAGAN: efficient tools for large-scale multiple alignment of genomic DNAMichael Brudno
Department of Computer Science, Stanford University, Stanford, California 94305-9010, USA
Genome Res 13:721-31. 2003..Multi-LAGAN is a practical method for generating multiple alignments of long genomic sequences at any evolutionary distance. Our systems are publicly available at http://lagan.stanford.edu...
Multiple alignment of protein sequences with repeats and rearrangementsTu Minh Phuong
Department of Computer Science, Posts and Telecommunications Institute of Technology, Hanoi, Vietnam
Nucleic Acids Res 34:5932-42. 2006..We conclude that ProDA is a practical tool for automated alignment of protein sequences with repeats and rearrangements in their domain architecture...
Evolution of genes and genomes on the Drosophila phylogenyAndrew G Clark
Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA
Nature 450:203-18. 2007..These may prove to underlie differences in the ecology and behaviour of these diverse species...
