M Diehn

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. ncbi request reprint Comparing functional genomic datasets: lessons from DNA microarray analyses of host-pathogen interactions
    M Diehn
    Department of Biochemistry, CCSR 2250, 269 Campus Drive, Stanford, CA 94305, USA
    Curr Opin Microbiol 4:95-101. 2001
  2. pmc SOURCE: a unified genomic resource of functional annotations, ontologies, and gene expression data
    Maximilian Diehn
    Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305, USA
    Nucleic Acids Res 31:219-23. 2003
  3. pmc Cell-type specific gene expression profiles of leukocytes in human peripheral blood
    Chana Palmer
    Department of Genetics, Stanford University School of Medicine, Stanford, USA
    BMC Genomics 7:115. 2006
  4. pmc Stereotactic ablative radiotherapy should be combined with a hypoxic cell radiosensitizer
    J Martin Brown
    Department of Radiation Oncology, Stanford University School of Medicine, California 94305, USA
    Int J Radiat Oncol Biol Phys 78:323-7. 2010
  5. pmc Transcriptional programs activated by exposure of human prostate cancer cells to androgen
    Samuel E DePrimo
    Department of Urology, Room S 287, Stanford University School of Medicine, Stanford, CA 94305, USA
    Genome Biol 3:RESEARCH0032. 2002
  6. pmc Gene expression patterns in ovarian carcinomas
    Marci E Schaner
    Stanford University School of Medicine, Stanford, California 94305 5151, USA
    Mol Biol Cell 14:4376-86. 2003
  7. pmc A method for detecting and correcting feature misidentification on expression microarrays
    I Ping Tu
    Functional Genomics Facility, Stanford University School of Medicine, Stanford, CA, USA
    BMC Genomics 5:64. 2004
  8. pmc Differential gene expression in anatomical compartments of the human eye
    Jennifer J Diehn
    Department of Ophthalmology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Genome Biol 6:R74. 2005
  9. pmc Stereotyped and specific gene expression programs in human innate immune responses to bacteria
    Jennifer C Boldrick
    Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 99:972-7. 2002
  10. pmc Genome-scale identification of membrane-associated human mRNAs
    Maximilian Diehn
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California, USA
    PLoS Genet 2:e11. 2006

Collaborators

Detail Information

Publications21

  1. ncbi request reprint Comparing functional genomic datasets: lessons from DNA microarray analyses of host-pathogen interactions
    M Diehn
    Department of Biochemistry, CCSR 2250, 269 Campus Drive, Stanford, CA 94305, USA
    Curr Opin Microbiol 4:95-101. 2001
    ..Comparisons between these large, highly parallel sets of experimental observations also emphasize important technical and experimental design issues as future challenges...
  2. pmc SOURCE: a unified genomic resource of functional annotations, ontologies, and gene expression data
    Maximilian Diehn
    Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305, USA
    Nucleic Acids Res 31:219-23. 2003
    ..SOURCE is available at http://source.stanford.edu...
  3. pmc Cell-type specific gene expression profiles of leukocytes in human peripheral blood
    Chana Palmer
    Department of Genetics, Stanford University School of Medicine, Stanford, USA
    BMC Genomics 7:115. 2006
    ..We did this by comparing the global gene expression profiles of purified B-cells, CD4+ T-cells, CD8+ T-cells, granulocytes, and lymphocytes using cDNA microarrays...
  4. pmc Stereotactic ablative radiotherapy should be combined with a hypoxic cell radiosensitizer
    J Martin Brown
    Department of Radiation Oncology, Stanford University School of Medicine, California 94305, USA
    Int J Radiat Oncol Biol Phys 78:323-7. 2010
    ....
  5. pmc Transcriptional programs activated by exposure of human prostate cancer cells to androgen
    Samuel E DePrimo
    Department of Urology, Room S 287, Stanford University School of Medicine, Stanford, CA 94305, USA
    Genome Biol 3:RESEARCH0032. 2002
    ..We used DNA microarrays, representing approximately 18,000 genes, to examine the temporal program of gene expression following treatment of the human prostate cancer cell line LNCaP with a synthetic androgen...
  6. pmc Gene expression patterns in ovarian carcinomas
    Marci E Schaner
    Stanford University School of Medicine, Stanford, California 94305 5151, USA
    Mol Biol Cell 14:4376-86. 2003
    ....
  7. pmc A method for detecting and correcting feature misidentification on expression microarrays
    I Ping Tu
    Functional Genomics Facility, Stanford University School of Medicine, Stanford, CA, USA
    BMC Genomics 5:64. 2004
    ..In this paper, we describe our statistical methods to detect the inconsistencies in microarray data that arise from process errors, and discuss our technique to locate and fix these errors...
  8. pmc Differential gene expression in anatomical compartments of the human eye
    Jennifer J Diehn
    Department of Ophthalmology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Genome Biol 6:R74. 2005
    ..We set out to systematically characterize the global gene expression patterns that specify the distinctive characteristics of the various eye compartments...
  9. pmc Stereotyped and specific gene expression programs in human innate immune responses to bacteria
    Jennifer C Boldrick
    Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 99:972-7. 2002
    ..Modulation of this host-response program by bacterial virulence mechanisms was an important source of variation in the response to different bacteria...
  10. pmc Genome-scale identification of membrane-associated human mRNAs
    Maximilian Diehn
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California, USA
    PLoS Genet 2:e11. 2006
    ..The large-scale annotation of subcellular localization reported here will serve as a reference database and will aid in the rational design of diagnostic tests and molecular therapies for diverse diseases...
  11. pmc Individuality and variation in gene expression patterns in human blood
    Adeline R Whitney
    Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 100:1896-901. 2003
    ..These data help to define human individuality and provide a database with which disease-associated gene expression patterns can be compared...
  12. pmc In vivo regulation of human skeletal muscle gene expression by thyroid hormone
    Karine Clement
    Department of Pediatrics and Genetics, Howard Hughes Medical Institute, Beckman Center, Stanford University School of Medicine, Stanford, California 94305, USA
    Genome Res 12:281-91. 2002
    ..These results define molecular signatures that help to understand the physiology and pathophysiology of thyroid hormone action...
  13. pmc Transcriptional response of human mast cells stimulated via the Fc(epsilon)RI and identification of mast cells as a source of IL-11
    Koichi Sayama
    Department of Pathology, Stanford University School of Medicine, Stanford, California, USA
    BMC Immunol 3:5. 2002
    ..To search for new mast cell products, we used complementary DNA microarrays to analyze gene expression in human umbilical cord blood-derived mast cells stimulated via the high-affinity IgE receptor (Fc(epsilon)RI)...
  14. pmc Transformation of follicular lymphoma to diffuse large-cell lymphoma: alternative patterns with increased or decreased expression of c-myc and its regulated genes
    Izidore S Lossos
    Division of Oncology, Department of Medicine, Stanford Genome Technology Center, and Howard Hughes Medical Institute, Stanford, CA 94305 5306, USA
    Proc Natl Acad Sci U S A 99:8886-91. 2002
    ....
  15. pmc Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation
    Maximilian Diehn
    Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 99:11796-801. 2002
    ....
  16. ncbi request reprint Type I collagen is overexpressed in medulloblastoma as a component of tumor microenvironment
    Yu Liang
    Department of Neurological Surgery, Brain Tumor Research Center, University of California San Francisco, San Francisco, CA 94143, USA
    J Neurooncol 86:133-41. 2008
    ....
  17. pmc T cell receptor-independent basal signaling via Erk and Abl kinases suppresses RAG gene expression
    Jeroen P Roose
    Department of Medicine, University of California, San Francisco, USA
    PLoS Biol 1:E53. 2003
    ..Our data suggest that physiologic gene expression programs depend upon tonic activity of signaling pathways independent of receptor ligation...
  18. pmc Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme
    Yu Liang
    Preuss Laboratory for Molecular Neuro oncology and Department of Neurological Surgery, University of California San Francisco, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 102:5814-9. 2005
    ..Our analyses thus identify and validate a prognostic marker of both biologic and clinical significance and provide a series of putative markers for additional evaluation...
  19. ncbi request reprint Cancer stem cells and radiotherapy: new insights into tumor radioresistance
    Maximilian Diehn
    J Natl Cancer Inst 98:1755-7. 2006
  20. ncbi request reprint Isolation and molecular characterization of cancer stem cells in MMTV-Wnt-1 murine breast tumors
    Robert W Cho
    Department of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan, USA
    Stem Cells 26:364-71. 2008
    ..These studies suggest that there is a cancer stem cell compartment in the MMTV-Wnt-1 murine breast tumor and that there is a clinical utility of this model for the study of cancer stem cells...
  21. pmc Identification of noninvasive imaging surrogates for brain tumor gene-expression modules
    Maximilian Diehn
    Department of Radiology, University of California San Diego Medical Center, San Diego, CA 92103, USA
    Proc Natl Acad Sci U S A 105:5213-8. 2008
    ..Our findings provide an in vivo portrait of genome-wide gene expression in GBM and offer a potential strategy for noninvasively selecting patients who may be candidates for individualized therapies...