Research Topics
| M DiehnSummaryAffiliation: Stanford University Country: USA Publications
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Detail Information
Publications
Comparing functional genomic datasets: lessons from DNA microarray analyses of host-pathogen interactionsM Diehn
Department of Biochemistry, CCSR 2250, 269 Campus Drive, Stanford, CA 94305, USA
Curr Opin Microbiol 4:95-101. 2001..Comparisons between these large, highly parallel sets of experimental observations also emphasize important technical and experimental design issues as future challenges...
SOURCE: a unified genomic resource of functional annotations, ontologies, and gene expression dataMaximilian Diehn
Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305, USA
Nucleic Acids Res 31:219-23. 2003..SOURCE is available at http://source.stanford.edu...
Cell-type specific gene expression profiles of leukocytes in human peripheral bloodChana Palmer
Department of Genetics, Stanford University School of Medicine, Stanford, USA
BMC Genomics 7:115. 2006..We did this by comparing the global gene expression profiles of purified B-cells, CD4+ T-cells, CD8+ T-cells, granulocytes, and lymphocytes using cDNA microarrays...- Stereotactic ablative radiotherapy should be combined with a hypoxic cell radiosensitizerJ Martin Brown
Department of Radiation Oncology, Stanford University School of Medicine, California 94305, USA
Int J Radiat Oncol Biol Phys 78:323-7. 2010.... - Transcriptional programs activated by exposure of human prostate cancer cells to androgenSamuel E DePrimo
Department of Urology, Room S 287, Stanford University School of Medicine, Stanford, CA 94305, USA
Genome Biol 3:RESEARCH0032. 2002..We used DNA microarrays, representing approximately 18,000 genes, to examine the temporal program of gene expression following treatment of the human prostate cancer cell line LNCaP with a synthetic androgen... - Gene expression patterns in ovarian carcinomasMarci E Schaner
Stanford University School of Medicine, Stanford, California 94305 5151, USA
Mol Biol Cell 14:4376-86. 2003.... - A method for detecting and correcting feature misidentification on expression microarraysI Ping Tu
Functional Genomics Facility, Stanford University School of Medicine, Stanford, CA, USA
BMC Genomics 5:64. 2004..In this paper, we describe our statistical methods to detect the inconsistencies in microarray data that arise from process errors, and discuss our technique to locate and fix these errors... - Differential gene expression in anatomical compartments of the human eyeJennifer J Diehn
Department of Ophthalmology, Stanford University School of Medicine, Stanford, CA 94305, USA
Genome Biol 6:R74. 2005..We set out to systematically characterize the global gene expression patterns that specify the distinctive characteristics of the various eye compartments... - Stereotyped and specific gene expression programs in human innate immune responses to bacteriaJennifer C Boldrick
Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA
Proc Natl Acad Sci U S A 99:972-7. 2002..Modulation of this host-response program by bacterial virulence mechanisms was an important source of variation in the response to different bacteria... - Genome-scale identification of membrane-associated human mRNAsMaximilian Diehn
Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California, USA
PLoS Genet 2:e11. 2006..The large-scale annotation of subcellular localization reported here will serve as a reference database and will aid in the rational design of diagnostic tests and molecular therapies for diverse diseases... - Individuality and variation in gene expression patterns in human bloodAdeline R Whitney
Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA
Proc Natl Acad Sci U S A 100:1896-901. 2003..These data help to define human individuality and provide a database with which disease-associated gene expression patterns can be compared... - In vivo regulation of human skeletal muscle gene expression by thyroid hormoneKarine Clement
Department of Pediatrics and Genetics, Howard Hughes Medical Institute, Beckman Center, Stanford University School of Medicine, Stanford, California 94305, USA
Genome Res 12:281-91. 2002..These results define molecular signatures that help to understand the physiology and pathophysiology of thyroid hormone action... - Transcriptional response of human mast cells stimulated via the Fc(epsilon)RI and identification of mast cells as a source of IL-11Koichi Sayama
Department of Pathology, Stanford University School of Medicine, Stanford, California, USA
BMC Immunol 3:5. 2002..To search for new mast cell products, we used complementary DNA microarrays to analyze gene expression in human umbilical cord blood-derived mast cells stimulated via the high-affinity IgE receptor (Fc(epsilon)RI)... - Transformation of follicular lymphoma to diffuse large-cell lymphoma: alternative patterns with increased or decreased expression of c-myc and its regulated genesIzidore S Lossos
Division of Oncology, Department of Medicine, Stanford Genome Technology Center, and Howard Hughes Medical Institute, Stanford, CA 94305-5306, USA
Proc Natl Acad Sci U S A 99:8886-91. 2002.... - Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activationMaximilian Diehn
Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305, USA
Proc Natl Acad Sci U S A 99:11796-801. 2002.... - Type I collagen is overexpressed in medulloblastoma as a component of tumor microenvironmentYu Liang
Department of Neurological Surgery, Brain Tumor Research Center, University of California San Francisco, San Francisco, CA 94143, USA
J Neurooncol 86:133-41. 2008.... - T cell receptor-independent basal signaling via Erk and Abl kinases suppresses RAG gene expressionJeroen P Roose
Department of Medicine, University of California, San Francisco, USA
PLoS Biol 1:E53. 2003..Our data suggest that physiologic gene expression programs depend upon tonic activity of signaling pathways independent of receptor ligation... - Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiformeYu Liang
Preuss Laboratory for Molecular Neuro oncology and Department of Neurological Surgery, University of California San Francisco, San Francisco, CA 94143, USA
Proc Natl Acad Sci U S A 102:5814-9. 2005..Our analyses thus identify and validate a prognostic marker of both biologic and clinical significance and provide a series of putative markers for additional evaluation... - Cancer stem cells and radiotherapy: new insights into tumor radioresistanceMaximilian Diehn
J Natl Cancer Inst 98:1755-7. 2006 - Isolation and molecular characterization of cancer stem cells in MMTV-Wnt-1 murine breast tumorsRobert W Cho
Department of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan, USA
Stem Cells 26:364-71. 2008..These studies suggest that there is a cancer stem cell compartment in the MMTV-Wnt-1 murine breast tumor and that there is a clinical utility of this model for the study of cancer stem cells... - Identification of noninvasive imaging surrogates for brain tumor gene-expression modulesMaximilian Diehn
Department of Radiology, University of California San Diego Medical Center, San Diego, CA 92103, USA
Proc Natl Acad Sci U S A 105:5213-8. 2008..Our findings provide an in vivo portrait of genome-wide gene expression in GBM and offer a potential strategy for noninvasively selecting patients who may be candidates for individualized therapies...