KARL ALEXANDER DEISSEROTH

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. doi request reprint Dopaminergic Dynamics Contributing to Social Behavior
    Lisa A Gunaydin
    The Gladstone Institutes, University of California, San Francisco, California 94158
    Cold Spring Harb Symp Quant Biol 79:221-7. 2014
  2. doi request reprint Engineering approaches to illuminating brain structure and dynamics
    Karl Deisseroth
    Department of Bioengineering, Stanford University, Stanford, CA 94305, USA Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA CNC Program, Stanford University, Stanford, CA 94305, USA Electronic address
    Neuron 80:568-77. 2013
  3. ncbi request reprint Dynamic multiphosphorylation passwords for activity-dependent gene expression
    Karl Deisseroth
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA
    Neuron 34:179-82. 2002
  4. pmc Next-generation optical technologies for illuminating genetically targeted brain circuits
    Karl Deisseroth
    Department of Bioengineering, Stanford University, Stanford, California 94305, USA
    J Neurosci 26:10380-6. 2006
  5. ncbi request reprint A role for circuit homeostasis in adult neurogenesis
    Leslie A Meltzer
    Department of Bioengineering, Neuroscience Program, Stanford University, W083 Clark Center, 318 Campus Drive West, Stanford, CA 94305, USA
    Trends Neurosci 28:653-60. 2005
  6. ncbi request reprint Multimodal fast optical interrogation of neural circuitry
    Feng Zhang
    Department of Bioengineering, Stanford University, Stanford, California 94305, USA
    Nature 446:633-9. 2007
  7. ncbi request reprint Excitation-neurogenesis coupling in adult neural stem/progenitor cells
    Karl Deisseroth
    Nancy Pritzker Laboratory, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA
    Neuron 42:535-52. 2004
  8. ncbi request reprint Circuit-breakers: optical technologies for probing neural signals and systems
    Feng Zhang
    Department of Bioengineering, W083 Clark Center, 318 Campus Drive West, Stanford University, California, USA
    Nat Rev Neurosci 8:577-81. 2007
  9. ncbi request reprint Integration of light-controlled neuronal firing and fast circuit imaging
    Raag D Airan
    Department of Bioengineering, Stanford University, CA, United States
    Curr Opin Neurobiol 17:587-92. 2007
  10. ncbi request reprint Millisecond-timescale, genetically targeted optical control of neural activity
    Edward S Boyden
    Department of Bioengineering, Stanford University, 318 Campus Drive West, Stanford, California 94305, USA
    Nat Neurosci 8:1263-8. 2005

Research Grants

  1. Excitatory Activity Control of Adult Neurogenesis
    Karl Deisseroth; Fiscal Year: 2008

Collaborators

  • Gero Miesenbock
  • Robert Malenka
  • Edward S Boyden
  • Anna K Majewska
  • Michael Ehlers
  • Raag D Airan
  • Feng Zhang
  • Leslie A Meltzer
  • Madhuri Roy
  • Elbert S Hu
  • Lisa A Gunaydin
  • Hong Hua Li
  • Luis de Lecea
  • Ragu Vijaykumar
  • Benjamin R Arenkiel
  • Antoine R Adamantidis
  • Viviana Gradinaru
  • Remy Durand
  • Hannah Bernstein
  • Joseph H Bayle
  • Feng Ding
  • Katharine C Harrison
  • Lief E Fenno
  • Richard Paylor
  • Uta Francke
  • Birgit Halm
  • Corinne M Spencer
  • Unsal Kuscuoglu
  • Alessandra Splendore
  • Elena Wright
  • Kimberly R Thompson
  • Guoping Feng
  • Ian G Davison
  • Alexander Gottschalk
  • Kenneth Kay
  • Li Ping Wang
  • Alexander M Aravanis
  • Georg Nagel
  • Catia Feliciano
  • Ernst Bamberg
  • Jana F Liewald
  • Han Chen
  • Natalie Watzke
  • Joao Peca
  • George J Augustine
  • Martin Brauner
  • Yuqing Gong
  • Phillip G Wood
  • Antoine Adamantidis
  • Raghu Yabaluri

Detail Information

Publications16

  1. doi request reprint Dopaminergic Dynamics Contributing to Social Behavior
    Lisa A Gunaydin
    The Gladstone Institutes, University of California, San Francisco, California 94158
    Cold Spring Harb Symp Quant Biol 79:221-7. 2014
    ..Here, we consider current knowledge on the role of brain reward circuitry in same-sex social behavior and describe findings from new methods for probing how this circuitry governs social motivation in health and disease. ..
  2. doi request reprint Engineering approaches to illuminating brain structure and dynamics
    Karl Deisseroth
    Department of Bioengineering, Stanford University, Stanford, CA 94305, USA Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA CNC Program, Stanford University, Stanford, CA 94305, USA Electronic address
    Neuron 80:568-77. 2013
    ..These research areas are poised for rapid growth and will likely be central to the practice of neuroscience well into the future. ..
  3. ncbi request reprint Dynamic multiphosphorylation passwords for activity-dependent gene expression
    Karl Deisseroth
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA
    Neuron 34:179-82. 2002
    ....
  4. pmc Next-generation optical technologies for illuminating genetically targeted brain circuits
    Karl Deisseroth
    Department of Bioengineering, Stanford University, Stanford, California 94305, USA
    J Neurosci 26:10380-6. 2006
    ..Here we explore key recent advances that unite optical and genetic approaches, focusing on promising techniques that either allow novel studies of neural dynamics and behavior or provide fresh perspectives on classic model systems...
  5. ncbi request reprint A role for circuit homeostasis in adult neurogenesis
    Leslie A Meltzer
    Department of Bioengineering, Neuroscience Program, Stanford University, W083 Clark Center, 318 Campus Drive West, Stanford, CA 94305, USA
    Trends Neurosci 28:653-60. 2005
    ....
  6. ncbi request reprint Multimodal fast optical interrogation of neural circuitry
    Feng Zhang
    Department of Bioengineering, Stanford University, Stanford, California 94305, USA
    Nature 446:633-9. 2007
    ..NpHR and ChR2 form a complete system for multimodal, high-speed, genetically targeted, all-optical interrogation of living neural circuits...
  7. ncbi request reprint Excitation-neurogenesis coupling in adult neural stem/progenitor cells
    Karl Deisseroth
    Nancy Pritzker Laboratory, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA
    Neuron 42:535-52. 2004
    ....
  8. ncbi request reprint Circuit-breakers: optical technologies for probing neural signals and systems
    Feng Zhang
    Department of Bioengineering, W083 Clark Center, 318 Campus Drive West, Stanford University, California, USA
    Nat Rev Neurosci 8:577-81. 2007
    ..These tools could lead to the development of precise neuromodulation technologies for animal models of disease and clinical neuropsychiatry...
  9. ncbi request reprint Integration of light-controlled neuronal firing and fast circuit imaging
    Raag D Airan
    Department of Bioengineering, Stanford University, CA, United States
    Curr Opin Neurobiol 17:587-92. 2007
    ..Together these neuroengineering advances raise the exciting prospect of determining the role-specific cell types play in modulating neural activity flow in neuropsychiatric disease...
  10. ncbi request reprint Millisecond-timescale, genetically targeted optical control of neural activity
    Edward S Boyden
    Department of Bioengineering, Stanford University, 318 Campus Drive West, Stanford, California 94305, USA
    Nat Neurosci 8:1263-8. 2005
    ..This technology allows the use of light to alter neural processing at the level of single spikes and synaptic events, yielding a widely applicable tool for neuroscientists and biomedical engineers...
  11. ncbi request reprint High-speed imaging reveals neurophysiological links to behavior in an animal model of depression
    Raag D Airan
    Department of Bioengineering, Stanford University, Stanford, CA 94305, USA
    Science 317:819-23. 2007
    ..Our results define a circuit-level neurophysiological endophenotype for affective behavior and suggest an approach to understanding circuit-level substrates underlying psychiatric disease symptoms...
  12. doi request reprint Temporally precise in vivo control of intracellular signalling
    Raag D Airan
    Department of Bioengineering, Stanford University, Stanford, California 94305, USA
    Nature 458:1025-9. 2009
    ..The optoXR approach allows testing of hypotheses regarding the causal impact of biochemical signalling in behaving mammals, in a targetable and temporally precise manner...
  13. pmc Induced chromosome deletions cause hypersociability and other features of Williams-Beuren syndrome in mice
    Hong Hua Li
    Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA
    EMBO Mol Med 1:50-65. 2009
    ..Together, these partial deletion mice replicate crucial aspects of the human disorder and serve to identify genes and gene networks contributing to the neural substrates of complex behaviours and behavioural disorders...
  14. pmc Optogenetic interrogation of neural circuits: technology for probing mammalian brain structures
    Feng Zhang
    Department of Bioengineering, Stanford University, Stanford, California, USA
    Nat Protoc 5:439-56. 2010
    ..Together, these methods may help in providing circuit-level insight into the dynamics underlying complex mammalian behaviors in health and disease...
  15. pmc In vivo light-induced activation of neural circuitry in transgenic mice expressing channelrhodopsin-2
    Benjamin R Arenkiel
    Howard Hughes Medical Institute, Duke University Medical Center, Durham, NC 27710, USA
    Neuron 54:205-18. 2007
    ....
  16. doi request reprint Brain circuit dynamics
    Elbert S Hu
    Am J Psychiatry 165:800. 2008

Research Grants1

  1. Excitatory Activity Control of Adult Neurogenesis
    Karl Deisseroth; Fiscal Year: 2008
    ..program that can be transitioned to a tenure-track position in a psychiatry department, where I look forward to continuing with 75-80% research and 20-25% patient care, and opportunities to teach and mentor others ..