Piero Dalerba

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. ncbi Cancer stem cells: models and concepts
    Piero Dalerba
    Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, California 94304, USA
    Annu Rev Med 58:267-84. 2007
  2. ncbi Cancer stem cells and tumor metastasis: first steps into uncharted territory
    Piero Dalerba
    Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Palo Alto, CA 94304, USA
    Cell Stem Cell 1:241-2. 2007
  3. doi Oncogenic miRNAs and the perils of losing control of a stem cell's epigenetic identity
    Piero Dalerba
    Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA 94305, USA
    Cell Stem Cell 13:5-6. 2013
  4. doi Identification of a cKit(+) colonic crypt base secretory cell that supports Lgr5(+) stem cells in mice
    Michael E Rothenberg
    Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford, California 94305, USA
    Gastroenterology 142:1195-1205.e6. 2012
  5. pmc Cancer stem cells from human breast tumors are involved in spontaneous metastases in orthotopic mouse models
    Huiping Liu
    Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Palo Alto, CA 94304, USA
    Proc Natl Acad Sci U S A 107:18115-20. 2010
  6. pmc Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells
    Yohei Shimono
    Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, 1050 Arastradero Road, Palo Alto, CA 94304, USA
    Cell 138:592-603. 2009
  7. doi Quantitative assessment of single-cell RNA-sequencing methods
    Angela R Wu
    Department of Bioengineering, Stanford University, Stanford, California, USA
    Nat Methods 11:41-6. 2014
  8. pmc The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors
    Stephen B Willingham
    Institute for Stem Cell Biology and Regenerative Medicine, Stanford University Medical Center, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 109:6662-7. 2012
  9. pmc Single-cell dissection of transcriptional heterogeneity in human colon tumors
    Piero Dalerba
    Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, California, USA
    Nat Biotechnol 29:1120-7. 2011
  10. ncbi The 5th International Society for Stem Cell Research (ISSCR) Annual Meeting, June 2007
    Vinagolu K Rajasekhar
    Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Rockefeller Research Laboratories, New York, New York 10021, USA
    Stem Cells 26:292-8. 2008

Collaborators

Detail Information

Publications13

  1. ncbi Cancer stem cells: models and concepts
    Piero Dalerba
    Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, California 94304, USA
    Annu Rev Med 58:267-84. 2007
    ..This model, first developed in human myeloid leukemias, is today being extended to solid tumors, such as breast and brain cancer. We review the biological basis and the therapeutic implications of the stem cell model of cancer...
  2. ncbi Cancer stem cells and tumor metastasis: first steps into uncharted territory
    Piero Dalerba
    Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Palo Alto, CA 94304, USA
    Cell Stem Cell 1:241-2. 2007
    ..In this issue of Cell Stem Cell, Hermann et al. (2007) analyze the relationship between CSC and tumor metastasis...
  3. doi Oncogenic miRNAs and the perils of losing control of a stem cell's epigenetic identity
    Piero Dalerba
    Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA 94305, USA
    Cell Stem Cell 13:5-6. 2013
    ..In back-to-back articles in Cell and Cell Stem Cell, Song et al. identify miR-22 as both a repressor of TET proteins and a powerful oncogene in the mammary epithelium and hematopoietic system. ..
  4. doi Identification of a cKit(+) colonic crypt base secretory cell that supports Lgr5(+) stem cells in mice
    Michael E Rothenberg
    Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford, California 94305, USA
    Gastroenterology 142:1195-1205.e6. 2012
    ..Although the colon also contains Lgr5(+) stem cells, it does not contain Paneth cells. We investigated the existence of colonic Paneth-like cells that have a distinct transcriptional signature and support Lgr5(+) stem cells...
  5. pmc Cancer stem cells from human breast tumors are involved in spontaneous metastases in orthotopic mouse models
    Huiping Liu
    Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Palo Alto, CA 94304, USA
    Proc Natl Acad Sci U S A 107:18115-20. 2010
    ....
  6. pmc Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells
    Yohei Shimono
    Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, 1050 Arastradero Road, Palo Alto, CA 94304, USA
    Cell 138:592-603. 2009
    ..The coordinated downregulation of three microRNA clusters and the similar functional regulation of clonal expansion by miR-200c provide a molecular link that connects BCSCs with normal stem cells...
  7. doi Quantitative assessment of single-cell RNA-sequencing methods
    Angela R Wu
    Department of Bioengineering, Stanford University, Stanford, California, USA
    Nat Methods 11:41-6. 2014
    ....
  8. pmc The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors
    Stephen B Willingham
    Institute for Stem Cell Biology and Regenerative Medicine, Stanford University Medical Center, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 109:6662-7. 2012
    ..CD47 is therefore a validated target for cancer therapies...
  9. pmc Single-cell dissection of transcriptional heterogeneity in human colon tumors
    Piero Dalerba
    Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, California, USA
    Nat Biotechnol 29:1120-7. 2011
    ....
  10. ncbi The 5th International Society for Stem Cell Research (ISSCR) Annual Meeting, June 2007
    Vinagolu K Rajasekhar
    Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Rockefeller Research Laboratories, New York, New York 10021, USA
    Stem Cells 26:292-8. 2008
    ..This hypothesis was widely explored at the conference to shed new light on the mechanisms of tumor origin and progression and to unveil novel antitumor therapeutic approaches...
  11. ncbi Identification of pancreatic cancer stem cells
    Chenwei Li
    Department of Surgery, University of Michigan Medical Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA
    Cancer Res 67:1030-7. 2007
    ....
  12. ncbi Immunity to cancer: attack and escape in T lymphocyte-tumor cell interaction
    Licia Rivoltini
    Units of Human Tumor Immunotherapy and Immunobiology, Istituto Nazionale Tumori, Milan, Italy
    Immunol Rev 188:97-113. 2002
    ..Finally, we discuss the role of inducible nitric oxide synthases in determining the inhibition of apoptosis in melanoma cells, which can make such tumor cells resistant to the T-cell attack...
  13. ncbi Cancer immunotherapy with peptide-based vaccines: what have we achieved? Where are we going?
    Giorgio Parmiani
    Unit of Immunotherapy of Human Tumors, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Italy
    J Natl Cancer Inst 94:805-18. 2002
    ....