Fredrik Dahl

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc Multigene amplification and massively parallel sequencing for cancer mutation discovery
    Fredrik Dahl
    Stanford Genome Technology Center, Stanford University, Palo Alto, CA 94304, USA
    Proc Natl Acad Sci U S A 104:9387-92. 2007
  2. pmc Multiplex amplification of all coding sequences within 10 cancer genes by Gene-Collector
    Simon Fredriksson
    Stanford Genome Technology Center, Bio X, Stanford, California 94305, USA
    Nucleic Acids Res 35:e47. 2007
  3. ncbi request reprint Multiplex amplification of large sets of human exons
    Gregory J Porreca
    Department of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA
    Nat Methods 4:931-6. 2007
  4. pmc Multiplex amplification enabled by selective circularization of large sets of genomic DNA fragments
    Fredrik Dahl
    Department of Genetics and Pathology, Rudbeck Laboratory Se 75185 Uppsala, Sweden
    Nucleic Acids Res 33:e71. 2005
  5. pmc PieceMaker: selection of DNA fragments for selector-guided multiplex amplification
    Johan Stenberg
    Department of Genetics and Pathology, Rudbeck Laboratory Se 751 85, Uppsala, Sweden
    Nucleic Acids Res 33:e72. 2005
  6. ncbi request reprint Analyzing genes using closing and replicating circles
    Mats Nilsson
    Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, SE 751 85 Uppsala, Sweden
    Trends Biotechnol 24:83-8. 2006
  7. pmc Real-time monitoring of rolling-circle amplification using a modified molecular beacon design
    Mats Nilsson
    Department of Molecular Cell Biology, Leiden University Medical Center, Wassenaarseweg 72, 2333 AL Leiden, The Netherlands
    Nucleic Acids Res 30:e66. 2002
  8. pmc MLGA--a rapid and cost-efficient assay for gene copy-number analysis
    Magnus Isaksson
    Department of Genetics and Pathology, Uppsala University, Rudbeck Laboratory, SE 751 85 Uppsala, Sweden
    Nucleic Acids Res 35:e115. 2007
  9. ncbi request reprint Evaluation of beta globin mRNA as an early marker of haemoglobin response to epoetin treatment
    Gunnar Birgegard
    Department of Haematology, University Hospital, Uppsala 751 85, Sweden
    Med Oncol 24:318-22. 2007
  10. ncbi request reprint Making ends meet in genetic analysis using padlock probes
    Mats Nilsson
    Beijer Laboratory, Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala, Sweden
    Hum Mutat 19:410-5. 2002

Collaborators

Detail Information

Publications10

  1. pmc Multigene amplification and massively parallel sequencing for cancer mutation discovery
    Fredrik Dahl
    Stanford Genome Technology Center, Stanford University, Palo Alto, CA 94304, USA
    Proc Natl Acad Sci U S A 104:9387-92. 2007
    ..Seven cancer cell lines and one normal genomic DNA sample were studied with multiple mutations and polymorphisms identified among the 10 genes. Mutations and polymorphisms in the TP53 gene were confirmed by traditional sequencing...
  2. pmc Multiplex amplification of all coding sequences within 10 cancer genes by Gene-Collector
    Simon Fredriksson
    Stanford Genome Technology Center, Bio X, Stanford, California 94305, USA
    Nucleic Acids Res 35:e47. 2007
    ..Gene-Collector has utility for numerous applications such as high throughput resequencing, SNP analyses, and pathogen detection...
  3. ncbi request reprint Multiplex amplification of large sets of human exons
    Gregory J Porreca
    Department of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA
    Nat Methods 4:931-6. 2007
    ..We anticipate that highly multiplexed methods for targeted amplification will enable the comprehensive resequencing of human exons at a fraction of the cost of whole-genome resequencing...
  4. pmc Multiplex amplification enabled by selective circularization of large sets of genomic DNA fragments
    Fredrik Dahl
    Department of Genetics and Pathology, Rudbeck Laboratory Se 75185 Uppsala, Sweden
    Nucleic Acids Res 33:e71. 2005
    ..Eighty-nine percent of the selectors generated PCR products that hybridized to the expected positions on the array, while little or no amplification artifacts were observed...
  5. pmc PieceMaker: selection of DNA fragments for selector-guided multiplex amplification
    Johan Stenberg
    Department of Genetics and Pathology, Rudbeck Laboratory Se 751 85, Uppsala, Sweden
    Nucleic Acids Res 33:e72. 2005
    ..The PieceMaker program alleviates this problem by selecting restriction enzymes to generate suitable fragments for selection, and generating the output data required to design the selector probes...
  6. ncbi request reprint Analyzing genes using closing and replicating circles
    Mats Nilsson
    Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, SE 751 85 Uppsala, Sweden
    Trends Biotechnol 24:83-8. 2006
    ..This review describes the recent developments in the technologies that use specific DNA circularization, coupled to DNA amplification through PCR or rolling-circle amplification, and addresses the great potential of these tools...
  7. pmc Real-time monitoring of rolling-circle amplification using a modified molecular beacon design
    Mats Nilsson
    Department of Molecular Cell Biology, Leiden University Medical Center, Wassenaarseweg 72, 2333 AL Leiden, The Netherlands
    Nucleic Acids Res 30:e66. 2002
    ..The method allows highly accurate quantification of circularized DNA over a broad concentration range by relating the signal from the test DNA circle to an internal reference DNA circle reporting in a distinct fluorescence color...
  8. pmc MLGA--a rapid and cost-efficient assay for gene copy-number analysis
    Magnus Isaksson
    Department of Genetics and Pathology, Uppsala University, Rudbeck Laboratory, SE 751 85 Uppsala, Sweden
    Nucleic Acids Res 35:e115. 2007
    ..We have developed a technique based on multiplex amplification of size-coded selectively circularized genomic fragments, which is robust, cheaper and more rapid than current multiplex targeted copy-number assays...
  9. ncbi request reprint Evaluation of beta globin mRNA as an early marker of haemoglobin response to epoetin treatment
    Gunnar Birgegard
    Department of Haematology, University Hospital, Uppsala 751 85, Sweden
    Med Oncol 24:318-22. 2007
    ..Compared to reticulocyte count, beta-globin mRNA is more reliable in the individual patient, but the clinical usefulness of the assay needs to be evaluated in further studies...
  10. ncbi request reprint Making ends meet in genetic analysis using padlock probes
    Mats Nilsson
    Beijer Laboratory, Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala, Sweden
    Hum Mutat 19:410-5. 2002
    ..We argue that the probes have the potential to render high-throughput genetic analyses precise and affordable...