Marcel M Daadi
Affiliation: Stanford University
Daadi M, Maag A, Steinberg G. Adherent self-renewable human embryonic stem cell-derived neural stem cell line: functional engraftment in experimental stroke model. PLoS ONE. 2008;3:e1644 pubmed publisher
..These properties indicate that this hNSC line may offer a renewable, homogenous source of neural cells that will be valuable for basic and translational research. ..
Daadi M, Li Z, Arac A, Grueter B, Sofilos M, Malenka R, et al
. Molecular and magnetic resonance imaging of human embryonic stem cell-derived neural stem cell grafts in ischemic rat brain. Mol Ther. 2009;17:1282-91 pubmed publisher
..Our data suggest that the combination of BLI and MRI modalities provides reliable real-time monitoring of cell fate. ..
Daadi M, Davis A, Arac A, Li Z, Maag A, Bhatnagar R, et al
. Human neural stem cell grafts modify microglial response and enhance axonal sprouting in neonatal hypoxic-ischemic brain injury. Stroke. 2010;41:516-23 pubmed publisher
..These results suggest that human neural stem cell transplants enhance endogenous brain repair through multiple modalities in response to HI. ..
Daadi M, Grueter B, Malenka R, Redmond D, Steinberg G. Dopaminergic neurons from midbrain-specified human embryonic stem cell-derived neural stem cells engrafted in a monkey model of Parkinson's disease. PLoS ONE. 2012;7:e41120 pubmed publisher
..The transplantation of these DA-induced hNSCs into the non-human primate MPTP model of PD demonstrated that the cells maintain their DA-induced phenotype, extend neurite outgrowths and express synaptic markers. ..
Daadi M, Hu S, Klausner J, Li Z, Sofilos M, Sun G, et al
. Imaging neural stem cell graft-induced structural repair in stroke. Cell Transplant. 2013;22:881-92 pubmed
..Longitudinal multimodal imaging provides insights into time course dose-dependent interactions between NSC grafts and structural changes in infarcted tissue. ..
Daadi M, Lee S, Arac A, Grueter B, Bhatnagar R, Maag A, et al
. Functional engraftment of the medial ganglionic eminence cells in experimental stroke model. Cell Transplant. 2009;18:815-26 pubmed publisher