Marcel M Daadi

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. ncbi request reprint Imaging neural stem cell graft-induced structural repair in stroke
    Marcel M Daadi
    Department of Neurosurgery, Stanford Stroke Center and Stanford Institute for Neuro Innovationand Translational Neurosciences, Stanford, CA, USA
    Cell Transplant 22:881-92. 2013
  2. pmc Dopaminergic neurons from midbrain-specified human embryonic stem cell-derived neural stem cells engrafted in a monkey model of Parkinson's disease
    Marcel M Daadi
    Department of Neurosurgery, Stanford School of Medicine, Stanford, California, United States of America
    PLoS ONE 7:e41120. 2012
  3. doi request reprint Novel paths towards neural cellular products for neurological disorders
    Marcel M Daadi
    Program in Stem Cell and Regenerative Biology, Sanford Burnham Medical Research Institute, La Jolla, CA 92037, USA
    Regen Med 6:25-30. 2011
  4. doi request reprint Human neural stem cell grafts modify microglial response and enhance axonal sprouting in neonatal hypoxic-ischemic brain injury
    Marcel M Daadi
    Department of Neurosurgery, Stanford Stroke Center, Stanford University School of Medicine, Stanford, Calif 94305 5487, USA
    Stroke 41:516-23. 2010
  5. doi request reprint Functional engraftment of the medial ganglionic eminence cells in experimental stroke model
    Marcel M Daadi
    Department of Neurosurgery and Stanford Stroke Center, Stanford University School of Medicine, Stanford, CA 94305 5487, USA
    Cell Transplant 18:815-26. 2009
  6. pmc Molecular and magnetic resonance imaging of human embryonic stem cell-derived neural stem cell grafts in ischemic rat brain
    Marcel M Daadi
    Department of Neurosurgery, Stanford Stroke Center, Stanford University School of Medicine, California 94305 5487, USA
    Mol Ther 17:1282-91. 2009
  7. doi request reprint Manufacturing neurons from human embryonic stem cells: biological and regulatory aspects to develop a safe cellular product for stroke cell therapy
    Marcel M Daadi
    Department of Neurosurgery and Stanford Stroke Center, MSLS P309, 1201 Welch Road, Stanford University School of Medicine, Stanford, CA 94305 5487, USA
    Regen Med 4:251-63. 2009
  8. pmc Adherent self-renewable human embryonic stem cell-derived neural stem cell line: functional engraftment in experimental stroke model
    Marcel M Daadi
    Department of Neurosurgery and Stanford Stroke Center, Stanford University School of Medicine, Stanford, California, USA
    PLoS ONE 3:e1644. 2008
  9. doi request reprint In vitro assays for neural stem cell differentiation: induction of dopaminergic phenotype
    Marcel M Daadi
    Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA
    Methods Mol Biol 438:205-12. 2008
  10. ncbi request reprint Activation and differentiation of endogenous neural stem cell progeny in the rat Parkinson animal model
    Marcel M Daadi
    Layton BioScience, Inc, Sunnyvale, CA, USA
    Methods Mol Biol 198:265-71. 2002

Detail Information

Publications12

  1. ncbi request reprint Imaging neural stem cell graft-induced structural repair in stroke
    Marcel M Daadi
    Department of Neurosurgery, Stanford Stroke Center and Stanford Institute for Neuro Innovationand Translational Neurosciences, Stanford, CA, USA
    Cell Transplant 22:881-92. 2013
    ..Longitudinal multimodal imaging provides insights into time course dose-dependent interactions between NSC grafts and structural changes in infarcted tissue...
  2. pmc Dopaminergic neurons from midbrain-specified human embryonic stem cell-derived neural stem cells engrafted in a monkey model of Parkinson's disease
    Marcel M Daadi
    Department of Neurosurgery, Stanford School of Medicine, Stanford, California, United States of America
    PLoS ONE 7:e41120. 2012
    ..The transplantation of these DA-induced hNSCs into the non-human primate MPTP model of PD demonstrated that the cells maintain their DA-induced phenotype, extend neurite outgrowths and express synaptic markers...
  3. doi request reprint Novel paths towards neural cellular products for neurological disorders
    Marcel M Daadi
    Program in Stem Cell and Regenerative Biology, Sanford Burnham Medical Research Institute, La Jolla, CA 92037, USA
    Regen Med 6:25-30. 2011
    ..In this article, we will review novel sources of neural cells and discuss current obstacles to developing them into viable cellular products for treating neurological disorders...
  4. doi request reprint Human neural stem cell grafts modify microglial response and enhance axonal sprouting in neonatal hypoxic-ischemic brain injury
    Marcel M Daadi
    Department of Neurosurgery, Stanford Stroke Center, Stanford University School of Medicine, Stanford, Calif 94305 5487, USA
    Stroke 41:516-23. 2010
    ..In the present study, we sought to investigate the efficacy of human neural stem cells derived from human embryonic stem cells in a rat model of neonatal HI and the mechanisms enhancing brain repair...
  5. doi request reprint Functional engraftment of the medial ganglionic eminence cells in experimental stroke model
    Marcel M Daadi
    Department of Neurosurgery and Stanford Stroke Center, Stanford University School of Medicine, Stanford, CA 94305 5487, USA
    Cell Transplant 18:815-26. 2009
    ....
  6. pmc Molecular and magnetic resonance imaging of human embryonic stem cell-derived neural stem cell grafts in ischemic rat brain
    Marcel M Daadi
    Department of Neurosurgery, Stanford Stroke Center, Stanford University School of Medicine, California 94305 5487, USA
    Mol Ther 17:1282-91. 2009
    ..Our data suggest that the combination of BLI and MRI modalities provides reliable real-time monitoring of cell fate...
  7. doi request reprint Manufacturing neurons from human embryonic stem cells: biological and regulatory aspects to develop a safe cellular product for stroke cell therapy
    Marcel M Daadi
    Department of Neurosurgery and Stanford Stroke Center, MSLS P309, 1201 Welch Road, Stanford University School of Medicine, Stanford, CA 94305 5487, USA
    Regen Med 4:251-63. 2009
    ..In this article, we will focus on hESCs and address the derivation of therapeutic neural stem cell lines from hESCs, as well as the biological and regulatory aspects to developing a safe cellular product for stroke cell therapy...
  8. pmc Adherent self-renewable human embryonic stem cell-derived neural stem cell line: functional engraftment in experimental stroke model
    Marcel M Daadi
    Department of Neurosurgery and Stanford Stroke Center, Stanford University School of Medicine, Stanford, California, USA
    PLoS ONE 3:e1644. 2008
    ..Studies have indicated that the direct enrichment method generates a heterogeneous population of cells that may contain residual undifferentiated stem cells that could lead to tumor formation in vivo...
  9. doi request reprint In vitro assays for neural stem cell differentiation: induction of dopaminergic phenotype
    Marcel M Daadi
    Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA
    Methods Mol Biol 438:205-12. 2008
    ....
  10. ncbi request reprint Activation and differentiation of endogenous neural stem cell progeny in the rat Parkinson animal model
    Marcel M Daadi
    Layton BioScience, Inc, Sunnyvale, CA, USA
    Methods Mol Biol 198:265-71. 2002
  11. ncbi request reprint In vitro assays for neural stem cell differentiation
    Marcel M Daadi
    Layton BioScience, Inc, Sunnyvale, CA, USA
    Methods Mol Biol 198:149-55. 2002
  12. ncbi request reprint Distribution of AAV2-hAADC-transduced cells after 3 years in Parkinsonian monkeys
    Marcel M Daadi
    Department of Neurosurgery, Stanford University, Stanford, USA
    Neuroreport 17:201-4. 2006
    ..Confocal analysis demonstrated that approximately 85% of the AADC+ cells were neuronal nuclei immunoreactive...