Lorinda Chung

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc Endothelin Receptor Antagonists for the Treatment of Raynaud's Phenomenon and Digital Ulcers in Systemic Sclerosis
    Kait Arefiev
    Division of Immunology and Rheumatology, Departments of Dermatology and Medicine, Stanford University School of Medicine, Palo Alto VA Health Care System, 3801 Miranda Avenue, Palo Alto, CA 94304, USA
    Int J Rheumatol 2011:201787. 2011
  2. doi request reprint Dyspnea assessment and pulmonary hypertension in patients with systemic sclerosis: utility of the University of California, San Diego, Shortness of Breath Questionnaire
    Lorinda Chung
    Stanford University and VA Palo Alto Health Care System, Palo Alto, California 94305, USA
    Arthritis Care Res (Hoboken) 65:454-63. 2013
  3. pmc Characterization of connective tissue disease-associated pulmonary arterial hypertension from REVEAL: identifying systemic sclerosis as a unique phenotype
    Lorinda Chung
    VA Palo Alto Health Care System, Palo Alto, CA 94304, USA
    Chest 138:1383-94. 2010
  4. doi request reprint MQX-503, a novel formulation of nitroglycerin, improves the severity of Raynaud's phenomenon: a randomized, controlled trial
    Lorinda Chung
    Stanford University, Stanford, California, and VA Palo Alto Health Care System, Palo Alto, CA 94304, USA
    Arthritis Rheum 60:870-7. 2009
  5. ncbi request reprint Hospitalizations and mortality in systemic sclerosis: results from the Nationwide Inpatient Sample
    L Chung
    Division of Immunology and Rheumatology, Stanford University, Stanford, CA, USA
    Rheumatology (Oxford) 46:1808-13. 2007
  6. ncbi request reprint Therapeutic options for digital ulcers in patients with systemic sclerosis
    Lorinda Chung
    Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA
    J Dtsch Dermatol Ges 5:460-5. 2007
  7. ncbi request reprint Digital ulcers in patients with systemic sclerosis
    Lorinda Chung
    Stanford University School of Medicine, Department of Immunology and Rheumatology, 1000 Welch Road, Suite 203, Stanford, CA 94305, USA
    Autoimmun Rev 5:125-8. 2006
  8. doi request reprint Atherosclerotic cardiovascular disease in hospitalized patients with systemic sclerosis: higher mortality than patients with lupus and rheumatoid arthritis
    Amish J Dave
    Stanford University School of Medicine, Palo Alto, California
    Arthritis Care Res (Hoboken) 66:323-7. 2014
  9. doi request reprint Hyperuricemia in young adults and risk of insulin resistance, prediabetes, and diabetes: a 15-year follow-up study
    Eswar Krishnan
    Department of Medicine, School of Medicine, Stanford University, Palo Alto, California, USA
    Am J Epidemiol 176:108-16. 2012
  10. pmc Pregnancy outcomes in systemic sclerosis, primary pulmonary hypertension, and sickle cell disease
    Eliza F Chakravarty
    Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, Palo Alto, California, USA
    Obstet Gynecol 111:927-34. 2008

Collaborators

Detail Information

Publications41

  1. pmc Endothelin Receptor Antagonists for the Treatment of Raynaud's Phenomenon and Digital Ulcers in Systemic Sclerosis
    Kait Arefiev
    Division of Immunology and Rheumatology, Departments of Dermatology and Medicine, Stanford University School of Medicine, Palo Alto VA Health Care System, 3801 Miranda Avenue, Palo Alto, CA 94304, USA
    Int J Rheumatol 2011:201787. 2011
    ..The purpose of this paper is to summarize the published studies and case reports evaluating the efficacy of endothelin receptor antagonists in the treatment of Raynaud's phenomenon and digital ulcers associated with systemic sclerosis...
  2. doi request reprint Dyspnea assessment and pulmonary hypertension in patients with systemic sclerosis: utility of the University of California, San Diego, Shortness of Breath Questionnaire
    Lorinda Chung
    Stanford University and VA Palo Alto Health Care System, Palo Alto, California 94305, USA
    Arthritis Care Res (Hoboken) 65:454-63. 2013
    ..We sought to assess the construct validity and responsiveness of the UCSD SOBQ in systemic sclerosis (SSc; scleroderma) patients with incident pulmonary hypertension (PH) and those at high risk of developing PH...
  3. pmc Characterization of connective tissue disease-associated pulmonary arterial hypertension from REVEAL: identifying systemic sclerosis as a unique phenotype
    Lorinda Chung
    VA Palo Alto Health Care System, Palo Alto, CA 94304, USA
    Chest 138:1383-94. 2010
    ..We used REVEAL to analyze the clinical features of patients with connective tissue disease-associated PAH (CTD-APAH)...
  4. doi request reprint MQX-503, a novel formulation of nitroglycerin, improves the severity of Raynaud's phenomenon: a randomized, controlled trial
    Lorinda Chung
    Stanford University, Stanford, California, and VA Palo Alto Health Care System, Palo Alto, CA 94304, USA
    Arthritis Rheum 60:870-7. 2009
    ..The purpose of this study was to evaluate the tolerability and efficacy of a novel formulation of topical nitroglycerin, MQX-503, in the treatment of RP in an ambulatory setting...
  5. ncbi request reprint Hospitalizations and mortality in systemic sclerosis: results from the Nationwide Inpatient Sample
    L Chung
    Division of Immunology and Rheumatology, Stanford University, Stanford, CA, USA
    Rheumatology (Oxford) 46:1808-13. 2007
    ..To study the causes of hospitalizations and predictors of subsequent adverse outcomes for contemporary cohorts of patients with systemic sclerosis (SSc) in the USA...
  6. ncbi request reprint Therapeutic options for digital ulcers in patients with systemic sclerosis
    Lorinda Chung
    Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA
    J Dtsch Dermatol Ges 5:460-5. 2007
    ..Intravenous or subcutaneous prostacyclins and digital or cervical sympathectomy should be considered for severe cases...
  7. ncbi request reprint Digital ulcers in patients with systemic sclerosis
    Lorinda Chung
    Stanford University School of Medicine, Department of Immunology and Rheumatology, 1000 Welch Road, Suite 203, Stanford, CA 94305, USA
    Autoimmun Rev 5:125-8. 2006
    ..Management of DU include non-pharmacologic and pharmacologic modalities. This review summarizes the current available and investigational therapies for the treatment and prevention of DU in patients with SSc...
  8. doi request reprint Atherosclerotic cardiovascular disease in hospitalized patients with systemic sclerosis: higher mortality than patients with lupus and rheumatoid arthritis
    Amish J Dave
    Stanford University School of Medicine, Palo Alto, California
    Arthritis Care Res (Hoboken) 66:323-7. 2014
    ..We utilized the US Nationwide Inpatient Sample to assess the frequency of and mortality risk associated with ASCVD among hospitalized SSc patients...
  9. doi request reprint Hyperuricemia in young adults and risk of insulin resistance, prediabetes, and diabetes: a 15-year follow-up study
    Eswar Krishnan
    Department of Medicine, School of Medicine, Stanford University, Palo Alto, California, USA
    Am J Epidemiol 176:108-16. 2012
    ..This observation was generally consistent across subgroups. The authors conclude that hyperuricemia in the midtwenties is an independent marker for predicting diabetes and prediabetes among young adults in the subsequent 15 years...
  10. pmc Pregnancy outcomes in systemic sclerosis, primary pulmonary hypertension, and sickle cell disease
    Eliza F Chakravarty
    Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, Palo Alto, California, USA
    Obstet Gynecol 111:927-34. 2008
    ..We estimated the nationwide occurrence of pregnancies in women with these conditions and compared pregnancy outcomes to the general obstetric population...
  11. ncbi request reprint A pilot trial of rituximab in the treatment of patients with dermatomyositis
    Lorinda Chung
    Department of Medicine, Stanford University School of Medicine, 900 Blake Wilbur Dr, Stanford, CA 94305, USA
    Arch Dermatol 143:763-7. 2007
    ..Using quantitative scales, we sought to evaluate the effects of rituximab therapy on muscle strength and skin disease in patients with dermatomyositis...
  12. pmc Tyrosine kinases in inflammatory dermatologic disease
    Ricardo T Paniagua
    Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA
    J Am Acad Dermatol 65:389-403. 2011
    ..In this review, we highlight TK signaling implicated in inflammatory dermatologic diseases, evaluate strategies aimed at inhibiting these aberrant signaling pathways, and discuss prospects for future drug development...
  13. pmc The mucocutaneous and systemic phenotype of dermatomyositis patients with antibodies to MDA5 (CADM-140): a retrospective study
    David Fiorentino
    Department of Dermatology, Stanford University School of Medicine, Stanford, California, USA
    J Am Acad Dermatol 65:25-34. 2011
    ....
  14. ncbi request reprint A pilot trial of treprostinil for the treatment and prevention of digital ulcers in patients with systemic sclerosis
    Lorinda Chung
    Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, California 94305, USA
    J Am Acad Dermatol 54:880-2. 2006
    ..Of the 5 patients completing therapy, ulcer size significantly decreased and no new ulcers occurred on continuous therapy. Although effective, the high rate of injection site reactions may limit the utility of this therapy...
  15. doi request reprint Validation of a novel radiographic scoring system for calcinosis affecting the hands of patients with systemic sclerosis
    Lorinda Chung
    Stanford University School of Medicine, Palo Alto, California
    Arthritis Care Res (Hoboken) 67:425-30. 2015
    ..We sought to develop and validate a novel radiographic scoring system for calcinosis affecting the hands of SSc patients for potential use in future clinical trials...
  16. pmc Cutaneous ulceration in dermatomyositis: association with anti-melanoma differentiation-associated gene 5 antibodies and interstitial lung disease
    Neera S Narang
    Stanford University, Stanford, California
    Arthritis Care Res (Hoboken) 67:667-72. 2015
    ..To identify clinical and serologic correlates of cutaneous ulcers in dermatomyositis (DM)...
  17. doi request reprint Localized cutaneous fibrosing disorders
    Aaliya Yaqub
    Division of Immunology and Rheumatology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
    Rheum Dis Clin North Am 39:347-64. 2013
    ..Particular emphasis is placed on clinical and histopathologic features that help the clinician differentiate between these disorders. Treatment options are briefly reviewed...
  18. ncbi request reprint Clinical trial design in scleroderma: where are we and where do we go next?
    Lorinda Chung
    Department of Medicine and Dermatology, Stanford University, Palo Alto, USA
    Clin Exp Rheumatol 30:S97-102. 2012
    ..Although SSc is a rare, heterogeneous disease, collaborative efforts led by the SCTC and other international networks will ultimately improve the design of clinical trials of promising therapies for SSc...
  19. pmc Hyperuricemia and the risk for subclinical coronary atherosclerosis--data from a prospective observational cohort study
    Eswar Krishnan
    Department of Medicine, Stanford University School of Medicine, 1000 Welch Road, Suite 203, Palo Alto, CA 94304, USA
    Arthritis Res Ther 13:R66. 2011
    ....
  20. doi request reprint Pathogenesis of dermatomyositis: role of cytokines and interferon
    Lily Kao
    Division of Immunology and Rheumatology, Stanford University School of Medicine, 1000 Welch Road, 203, Palo Alto, CA 94304, USA
    Curr Rheumatol Rep 13:225-32. 2011
    ..Although a great deal of progress has been made regarding the role of interferon in the disease, many critical questions remain unanswered...
  21. pmc Molecular framework for response to imatinib mesylate in systemic sclerosis
    Lorinda Chung
    Stanford University, Stanford, California, and VA Palo Alto Health Care System, Palo Alto, California
    Arthritis Rheum 60:584-91. 2009
    ....
  22. doi request reprint Monitoring and Diagnostic Approaches for Pulmonary Arterial Hypertension in Patients with Systemic Sclerosis
    Antonia Valenzuela
    Department of Immunology and Rheumatology, Stanford University School of Medicine, 1000 Welch Road, Suite 203, MC 5755, Palo Alto, CA 94304, USA
    Rheum Dis Clin North Am 41:489-506. 2015
    ..Once a diagnosis of PAH is confirmed by RHC, treatment with PAH-specific therapies should be initiated as soon as possible. ..
  23. doi request reprint Surgical treatment of systemic sclerosis--is it justified to offer peripheral sympathectomy earlier in the disease process?
    Arash Momeni
    Division of Plastic and Reconstructive Surgery, Stanford University Medical Center, Palo Alto, CA
    Microsurgery 35:441-6. 2015
    ..The purpose of the present study was to analyze the results of peripheral sympathectomy in patients with a confirmed diagnosis of SSc...
  24. pmc Identification of clinical features and autoantibodies associated with calcinosis in dermatomyositis
    Antonia Valenzuela
    Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, California
    JAMA Dermatol 150:724-9. 2014
    ..Identification of risk factors may provide a better understanding of the pathogenesis and ultimately therapy for this difficult clinical problem. Risk factors for calcinosis in adults with DM have not been extensively studied...
  25. ncbi request reprint Successful use of rituximab for cutaneous vasculitis
    Lorinda Chung
    Stanford University School of Medicine, Stanford, CA 94305, USA
    Arch Dermatol 142:1407-10. 2006
  26. pmc Multicriteria decision analysis methods with 1000Minds for developing systemic sclerosis classification criteria
    Sindhu R Johnson
    Division of Rheumatology, Department of Medicine, Toronto Western Hospital, University of Toronto, Ground Floor, East Wing, 399 Bathurst Street, Toronto, Ontario, Canada M5T 2S8 Division of Rheumatology, Department of Medicine, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada Electronic address
    J Clin Epidemiol 67:706-14. 2014
    ....
  27. doi request reprint Epidemiology and risk factors for pulmonary hypertension in systemic sclerosis
    Aaliya Yaqub
    Division of Immunology and Rheumatology, Stanford University, Stanford, CA, USA
    Curr Rheumatol Rep 15:302. 2013
    ..The ultimate objective in understanding the risk of developing PH in SSc is early diagnosis and early initiation of appropriate therapy with the hope for improved outcomes for patients with SSc-PH...
  28. doi request reprint Malignancy in the setting of the anti-synthetase syndrome
    Andrew Rozelle
    Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, USA
    J Clin Rheumatol 14:285-8. 2008
    ..We conclude that a thorough and expedited age-appropriate malignancy work up is indicated in all patients with a new diagnosis of DM, despite the presence of disease characteristics that are usually not associated with cancer...
  29. ncbi request reprint A pilot study of tumor necrosis factor inhibition in erosive/inflammatory osteoarthritis of the hands
    Molly D Magnano
    Division of Immunology and Rheumatology, Stanford University, Palo Alto, California 94304, USA
    J Rheumatol 34:1323-7. 2007
    ..To determine if anti-tumor necrosis factor (TNF) therapy (adalimumab) can safely improve symptoms of erosive/inflammatory osteoarthritis (EOA)...
  30. ncbi request reprint Systemic and localized scleroderma
    Lorinda Chung
    Department of Dermatology, Stanford University School of Medicine, CA 94305, USA
    Clin Dermatol 24:374-92. 2006
    ..The basic process of fibrosis, however, awaits proven, effective therapy...
  31. doi request reprint An analysis of connective tissue disease-associated interstitial lung disease at a US Tertiary Care Center: better survival in patients with systemic sclerosis
    Robert Su
    Department of Medicine, Division of Immunology and Rheumatology, Division of Pulmonary and Critical Care, Stanford University School of Medicine, Palo Alto, CA, USA
    J Rheumatol 38:693-701. 2011
    ....
  32. doi request reprint Calcinosis: pathophysiology and management
    Antonia Valenzuela
    Division of Immunology and Rheumatology, Stanford University School of Medicine, Palo Alto, California, USA
    Curr Opin Rheumatol 27:542-8. 2015
    ..This article reviews the most updated literature regarding the epidemiology, pathophysiology, diagnosis, and treatment of calcinosis cutis in patients with systemic sclerosis (SSc)...
  33. doi request reprint Digital Sympathectomy in Patients With Scleroderma: An Overview of the Practice and Referral Patterns and Perceptions of Rheumatologists
    Grace Chiou
    From the Division of Plastic and Reconstructive Surgery, Department of Surgery and Division of Immunology and Rheumatology, Department of Medicine, Stanford University Medical Center, Stanford, CA
    Ann Plast Surg 75:637-43. 2015
    ..Our hypothesis is that rheumatologists' practices largely influence their referral patterns for digital sympathectomy...
  34. doi request reprint Leukotriene B4 Activates Pulmonary Artery Adventitial Fibroblasts in Pulmonary Hypertension
    Jin Qian
    From the VA Palo Alto Health Care System, Palo Alto, CA J Q, W T, X J, R T, Y K S, E M S, A B T, M R N Department of Medicine, Division of Pulmonary and Critical Care Medicine J Q, W T, X J, R T, Y K S, E M S, A B T, S J, R T Z, M R N, Department of Immunology and Rheumatology A V, D F F, L C, and Department of Pediatrics M R, Stanford University School of Medicine, CA Department of Internal Medicine, Victoria Johnson Center for Obstructive Lung Diseases and Pulmonary and Critical Care Medicine Division, Virginia Commonwealth University, Richmond N F V Department of Internal Medicine, University of Michigan Health Systems, Ann Arbor M P G and Department of Pediatrics, Cardiovascular Pulmonary Research Laboratories, University of Colorado Denver School of Medicine, Finland
    Hypertension 66:1227-39. 2015
    ..This study uncovers a novel mechanism by which LTB4 further promotes pulmonary arterial hypertension pathogenesis, beyond its established effects on endothelial and smooth muscle cells, by activating adventitial fibroblasts. ..
  35. pmc Cardiac arrhythmias and conduction defects in systemic sclerosis
    Alessandra Vacca
    Unit and Chair of Rheumatology, University and A O U of Cagliari, Cagliari, Italy, Cardiology Department, Avicenne Hospital, Bobigny and Cochin Hospital, Paris XIII University, APHP, Paris, France, Department of Rheumatology, Hospital for Special Surgery, New York, NY, Stanford University School of Medicine, Stanford, VA Palo Alto Health Care System, Palo Alto, CA, USA, Rheumatology Unit, Royal Adelaide Hospital, North Terrace, Adelaide, SA, Australia, Health Science Center at Houston, University of Texas, Houston, TX, USA, St Vincent s Hospital, University of Melbourne, Fitzroy, Melbourne, Vic, Australia, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico, Scleroderma Program, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, Boston University School of Medicine, Boston, MA, USA, Rheumatology Division, Department of Internal Medicine, University of Florence, Florence, Italy, Department of Rheumatology, University Hospital Zurich
    Rheumatology (Oxford) 53:1172-7. 2014
    ..In addition, some therapeutic options in SSc patients may differ from those recommended in other populations...
  36. pmc Clinical presentation and evaluation of dermatomyositis
    Umaima Marvi
    Division of Immunology and Rheumatology, Stanford University, USA
    Indian J Dermatol 57:375-81. 2012
    ..This review summarizes the immunopathogenesis, clinical manifestations, and evaluation of patients with DM...
  37. pmc Baseline characteristics and follow-up in patients with normal haemodynamics versus borderline mean pulmonary arterial pressure in systemic sclerosis: results from the PHAROS registry
    Sangmee Bae
    Department of Internal Medicine, University of California, Los Angeles, California, USA
    Ann Rheum Dis 71:1335-42. 2012
    ..The objectives of this analysis were to examine the baseline characteristics in systemic sclerosis (SSc) with normal and borderline mPAP and to explore long-term outcomes in SSc patients with borderline mPAP versus normal haemodynamics...
  38. ncbi request reprint Antibodies in scleroderma: direct pathogenicity and phenotypic associations
    Lorinda Chung
    Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, 1000 Welch Road, Suite 203, Stanford, CA 94305, USA
    Curr Rheumatol Rep 6:156-63. 2004
    ..This review will summarize the various autoantibodies associated with scleroderma, their putative pathogenic roles, and their phenotypic correlations...