Affiliation: Stanford University
- Translating genomics into the clinic: moving to the post-Mendelian worldMildred K Cho
Stanford Center for Biomedical Ethics, Center for Integration of Research on Genetics and Ethics, Department of Pediatrics, Division of Genetics, Welch Road, Palo Alto, CA 94304, USA
Genome Med 1:7. 2009..We have far to go to assure basic levels of analytical validity or clinical validity of the diagnostic or predictive tools on offer, and to determine their clinical utility in the medical context...
- Patently unpatentable: implications of the Myriad court decision on genetic diagnosticsMildred Cho
Stanford Center for Biomedical Ethics, 1215 Welch Road, Stanford, CA 94305, USA
Trends Biotechnol 28:548-51. 2010..It is clear that the intellectual property model challenged by the Myriad decision will have to be replaced if new genetic technologies are to achieve their full potential in promoting 'the progress of science and useful arts'...
- Strangers at the benchside: research ethics consultationMildred K Cho
Stanford Center for Biomedical Ethics, Center for Integration of Research on Geneticsand Ethics, Palo Alto, CA 94304, USA
Am J Bioeth 8:4-13. 2008..We make preliminary recommendations for the structure and process of research ethics consultation, based on our initial experiences in a pilot program...
- Research conduct. Lessons of the stem cell scandalMildred K Cho
Stanford Center for Biomedical Ethics, Department of Pediatrics Palo Alto, CA 94304, USA
Science 311:614-5. 2006
- Forensic genetics and ethical, legal and social implications beyond the clinicMildred K Cho
Stanford Center for Biomedical Ethics, 701A Welch Road, Suite 1105, Palo Alto, California 94304, USA
Nat Genet 36:S8-12. 2004..Here we examine forensic genetics and argue that all geneticists should anticipate the ethical and social issues associated with nonmedical applications of genetic variation research...
- Effects of patents and licenses on the provision of clinical genetic testing servicesMildred K Cho
Center for Biomedical Ethics, Stanford University, Palo Alto, California, USA
J Mol Diagn 5:3-8. 2003..Furthermore, our findings suggest that clinical geneticists feel that their research is inhibited by patents. The effects of patents and licenses on patients' access to tests, and the costs and quality thereof, remains to be determined...
- Conflicts of interest in magnetic resonance imaging: issues in clinical practice and researchMildred K Cho
Stanford University Center for Biomedical Ethics, Palo Alto, California 94304, USA
Top Magn Reson Imaging 13:73-7. 2002..Finally, it is important for medical professionals who work with MRI to understand some of the characteristics of MRI that might increase the prevalence of conflicts of interest in clinical practice and research...
- Ethics. Issues in oocyte donation for stem cell researchDavid Magnus
Stanford Center for Biomedical Ethics and Department of Pediatrics, Stanford University, Palo Alto, CA 94304, USA
Science 308:1747-8. 2005
- Privacy issues in personalized medicineLaszlo T Vaszar
Stanford University School of Medicine, Division of Pulmonary and Critical Care, 300 Pasteur Drive, MC5236, Stanford, CA 94305 5236, USA
Pharmacogenomics 4:107-12. 2003..The genomic scans' magnitude, stability, implications to kin and ease of dissemination together represent a qualitatively different challenge compared to traditional, self-limited and often temporally transient medical information...
- Ethical implications of array comparative genomic hybridization in complex phenotypes: points to consider in researchHolly K Tabor
Stanford Center for Biomedical Ethics, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, California, USA
Genet Med 9:626-31. 2007..Our goal was to identify points to consider for researchers, clinicians, and patients/families to ensure responsible and ethical design, presentation, and interpretation of these kinds of studies...
- Ethics. Incidental findings in brain imaging researchJudy Illes
Center for Biomedical Ethics, Stanford University, Palo Alto, CA 94304, USA
Science 311:783-4. 2006
- Biomedical scientists' perceptions of ethical and social implications: is there a role for research ethics consultation?Jennifer B McCormick
Stanford Center for Biomedical Ethics, Stanford University, Palo Alto, California, USA
PLoS ONE 4:e4659. 2009..We conducted telephone interviews and focus groups in 2006 with researchers from Stanford University and a mailed survey in December 2006 to 7 research universities in the U.S...
- ELSI priorities for brain imagingJudy Illes
Stanford University, USA
Am J Bioeth 6:W24-31. 2006..We identified specific ethical, legal and social issues (ELSI) that highlight researcher obligations and the nonclinical impact of the technology at this new frontier...
- Thinking about the human neuron mouseHenry T Greely
Stanford University, CA, USA
Am J Bioeth 7:27-40. 2007
- Racial and ethnic categories in biomedical research: there is no baby in the bathwaterMildred K Cho
Stanford University, USA
J Law Med Ethics 34:497-9, 479. 2006..I argue that race is too undefined and fluid to be useful as a proxy for biology or genetics...
- Managing incidental findings in human subjects research: analysis and recommendationsSusan M Wolf
University of Minnesota, MN, USA
J Law Med Ethics 36:219-48, 211. 2008..We recommend a pathway and categorize IFs into those that must be disclosed to research participants, those that may be disclosed, and those that should not be disclosed...
- Research ethics and the challenge of whole-genome sequencingAmy L McGuire
Amy L McGuire is at the Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, Texas 77030, USA
Nat Rev Genet 9:152-6. 2008..Although the issues are not new, we discuss their implications for personal genomics and provide recommendations for appropriate management in the context of research involving individual whole-genome sequencing...
- A pilot survey on the licensing of DNA inventionsMichelle R Henry
University of Pennsylvania s Center for Bioethics, USA
J Law Med Ethics 31:442-9. 2003
- Genetics. DNA patenting and licensingMichelle R Henry
Center for Bioethics, University of Pennsylvania, Philadelphia, PA, 19104 3308, USA
Science 297:1279. 2002
- Financial conflict-of-interest policies in clinical research: issues for clinical investigatorsElizabeth A Boyd
Department of Clinical Pharmacy, University of California, San Francisco, 94143, USA
Acad Med 78:769-74. 2003....
- What are gene patents and why are people worried about them?Jon F Merz
Department of Medical Ethics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 3308, USA
Community Genet 8:203-8. 2005..Nonetheless, there are areas of concern, and policy makers, physicians and the public should be alert to ensure that the net social benefits of patenting human genes are maintained...
- Protecting subjects' interests in genetics researchJon F Merz
Center for Bioethics, University of Pennsylvania, 3401 Market Street, Suite 320, Philadelphia, PA 19104 3308, USA
Am J Hum Genet 70:965-71. 2002....
- A commentary on oocyte donation for stem cell research in South KoreaDavid Magnus
Am J Bioeth 6:W23-4. 2006
- Understanding incidental findings in the context of genetics and genomicsMildred K Cho
Department of Pediatrics at Stanford University, CA, USA
J Law Med Ethics 36:280-5, 212. 2008..What research results should be offered, and what should not be offered? For which research should individual results be offered to research participants, when should they be offered, how, and to whom?..
- Industry opposes genomic legislationJon F Merz
Nat Biotechnol 20:657; author reply 657. 2002
- Medicine. The future of personal genomicsAmy L McGuire
Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX 77030, USA
Science 317:1687. 2007
- Genetic research and health disparitiesPamela Sankar
Center for Bioethics, School of Medicine, University of Pennsylvania, Philadelphia 19104 3308, USA
JAMA 291:2985-9. 2004....
- Race and ethnicity in genetic researchPamela Sankar
Department of Medical Ethics Center for Bioethics Leonard Davis Institute for Health Economics, University of Pennsylvania, Philadelphia, PA 19130, USA
Am J Med Genet A 143:961-70. 2007..With limited exceptions, current practice does not reflect repeated recommendations for using race or ethnicity terms in genetic research. This study provides a baseline against which to measure future trends...
- What is in a cause? Exploring the relationship between genetic cause and felt stigmaPamela Sankar
Center for Bioethics, University of Pennsylvania, 3401 Market Street, Philadelphia, PA 19104, USA
Genet Med 8:33-42. 2006..However, whether a genetic or hereditary basis necessarily confers a stigma to a condition remains unexamined...
- Diagnostic testing fails the testJon F Merz
Center for Bioethics, University of Pennsylvania, Philadelphia, Pennsylvania 19104 3308, USA
Nature 415:577-9. 2002
- Center for Integrating Ethics & Genetic ResearchMildred Cho; Fiscal Year: 2007..The new models will be widely adoptable and will enable unprecedented consideration of genetic research ethics issues among the research community and the public. ..
- EFFECTS OF GENE PATENTS ON GENETIC TESTING AND RESEARCHMildred Cho; Fiscal Year: 2002..Our analysis will form inform public policy by indicating whether intellectual property policies or their implementation should be changed to encourage research and technology transfer, and if so, how. ..
- Toward a Framework for Policy Analysis of Microbiome ResearchPAMELA L SANKAR; Fiscal Year: 2010....