Sophia B Chernikova

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc R-loops and genomic instability in Bre1 (RNF20/40)-deficient cells
    Sophia B Chernikova
    Department of Radiation Oncology, Stanford University, Stanford, CA, USA
    Cell Cycle 11:2980-4. 2012
  2. pmc Deficiency in Bre1 impairs homologous recombination repair and cell cycle checkpoint response to radiation damage in mammalian cells
    Sophia B Chernikova
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305 5152, USA
    Radiat Res 174:558-65. 2010
  3. pmc Deficiency in mammalian histone H2B ubiquitin ligase Bre1 (Rnf20/Rnf40) leads to replication stress and chromosomal instability
    Sophia B Chernikova
    Department of Radiation Oncology, Stanford University, Stanford, California 94305, USA
    Cancer Res 72:2111-9. 2012
  4. doi request reprint The role of RAD6 in recombinational repair, checkpoints and meiosis via histone modification
    John C Game
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA
    DNA Repair (Amst) 8:470-82. 2009
  5. pmc Inhibiting homologous recombination for cancer therapy
    Sophia B Chernikova
    Department of Radiation Oncology, Stanford University, Stanford, CA USA
    Cancer Biol Ther 13:61-8. 2012
  6. pmc VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKC{delta}-driven migration
    Olga V Razorenova
    Department of Radiation Oncology, Center for Clinical Sciences Research, Stanford University School of Medicine, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 108:1931-6. 2011
  7. pmc The DNA repair endonuclease XPG interacts directly and functionally with the WRN helicase defective in Werner syndrome
    Kelly S Trego
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA
    Cell Cycle 10:1998-2007. 2011
  8. doi request reprint Homologous recombination is the principal pathway for the repair of DNA damage induced by tirapazamine in mammalian cells
    James W Evans
    Department of Radiation Oncology, Division of Radiation and Cancer Biology, Stanford University, Stanford, California 94305 5152, USA
    Cancer Res 68:257-65. 2008

Collaborators

Detail Information

Publications8

  1. pmc R-loops and genomic instability in Bre1 (RNF20/40)-deficient cells
    Sophia B Chernikova
    Department of Radiation Oncology, Stanford University, Stanford, CA, USA
    Cell Cycle 11:2980-4. 2012
    ....
  2. pmc Deficiency in Bre1 impairs homologous recombination repair and cell cycle checkpoint response to radiation damage in mammalian cells
    Sophia B Chernikova
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305 5152, USA
    Radiat Res 174:558-65. 2010
    ..Thus our data suggest that the observed defects in the radiation response of Bre1a/b-deficient cells are associated with reduced H3K79me2 and not with H4K20me2...
  3. pmc Deficiency in mammalian histone H2B ubiquitin ligase Bre1 (Rnf20/Rnf40) leads to replication stress and chromosomal instability
    Sophia B Chernikova
    Department of Radiation Oncology, Stanford University, Stanford, California 94305, USA
    Cancer Res 72:2111-9. 2012
    ....
  4. doi request reprint The role of RAD6 in recombinational repair, checkpoints and meiosis via histone modification
    John C Game
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA
    DNA Repair (Amst) 8:470-82. 2009
    ..However, the specific histone modification pathways involved diverge in these different eukaryotes...
  5. pmc Inhibiting homologous recombination for cancer therapy
    Sophia B Chernikova
    Department of Radiation Oncology, Stanford University, Stanford, CA USA
    Cancer Biol Ther 13:61-8. 2012
    ..We review strategies for identifying HR inhibitors and discuss current progress...
  6. pmc VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKC{delta}-driven migration
    Olga V Razorenova
    Department of Radiation Oncology, Center for Clinical Sciences Research, Stanford University School of Medicine, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 108:1931-6. 2011
    ..Furthermore, patient survival can be stratified by CDCP1 expression at the cell surface of the tumor. Taken together, our data indicates that CDCP1 protein might serve as a therapeutic target for CC-RCC...
  7. pmc The DNA repair endonuclease XPG interacts directly and functionally with the WRN helicase defective in Werner syndrome
    Kelly S Trego
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA
    Cell Cycle 10:1998-2007. 2011
    ..Taken together, our results suggest a novel function for XPG in S phase that is, at least in part, performed coordinately with WRN, and which may contribute to the severity of the phenotypes that occur upon loss of XPG...
  8. doi request reprint Homologous recombination is the principal pathway for the repair of DNA damage induced by tirapazamine in mammalian cells
    James W Evans
    Department of Radiation Oncology, Division of Radiation and Cancer Biology, Stanford University, Stanford, California 94305 5152, USA
    Cancer Res 68:257-65. 2008
    ....