Kiki Chang

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. ncbi request reprint Anomalous prefrontal-subcortical activation in familial pediatric bipolar disorder: a functional magnetic resonance imaging investigation
    Kiki Chang
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305 5540, USA
    Arch Gen Psychiatry 61:781-92. 2004
  2. pmc Effect of divalproex on brain morphometry, chemistry, and function in youth at high-risk for bipolar disorder: a pilot study
    Kiki Chang
    Division of Child and Adolescent Psychiatry, Stanford University School of Medicine, Stanford, California 94305 5540, USA
    J Child Adolesc Psychopharmacol 19:51-9. 2009
  3. pmc Brain glutamatergic characteristics of pediatric offspring of parents with bipolar disorder
    Manpreet Singh
    Department of Psychiatry and Behavioral Sciences, Division of Child and Adolescent Psychiatry, Stanford University School of Medicine, 401 Quarry Road, Stanford, CA 94305, USA
    Psychiatry Res 182:165-71. 2010
  4. pmc Increased subgenual cingulate cortex volume in pediatric bipolar disorder associated with mood stabilizer exposure
    Myles M Mitsunaga
    Pediatric Bipolar Disorders Program, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305, USA
    J Child Adolesc Psychopharmacol 21:149-55. 2011
  5. pmc Neurometabolite effects of response to quetiapine and placebo in adolescents with bipolar depression
    Kiki Chang
    Pediatric Bipolar Disorders Program, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305 5540, USA
    J Child Adolesc Psychopharmacol 22:261-8. 2012
  6. ncbi request reprint Divalproex sodium reduces overall aggression in youth at high risk for bipolar disorder
    Kirti Saxena
    Department of Psychiatry and Behavioral Sciences, Division of Child Psychiatry and Child Development, School of Medicine, Stanford University, 401 Quarry Road, Stanford, CA 94305, USA
    J Child Adolesc Psychopharmacol 16:252-9. 2006
  7. doi request reprint Atomoxetine as an adjunct therapy in the treatment of co-morbid attention-deficit/hyperactivity disorder in children and adolescents with bipolar I or II disorder
    Kiki Chang
    Pediatric Bipolar Disorders Program, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA
    J Child Adolesc Psychopharmacol 19:547-51. 2009
  8. pmc Subcortical volumetric correlates of anxiety in familial pediatric bipolar disorder: a preliminary investigation
    Diana I Simeonova
    Pediatric Bipolar Disorders Program, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305 5540, USA
    Psychiatry Res 173:113-20. 2009
  9. ncbi request reprint Cortical magnetic resonance imaging findings in familial pediatric bipolar disorder
    Kiki Chang
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA
    Biol Psychiatry 58:197-203. 2005
  10. doi request reprint The role of the amygdala in bipolar disorder development
    Amy Garrett
    Stanford University School of Medicine, CA 94305, USA
    Dev Psychopathol 20:1285-96. 2008

Collaborators

Detail Information

Publications29

  1. ncbi request reprint Anomalous prefrontal-subcortical activation in familial pediatric bipolar disorder: a functional magnetic resonance imaging investigation
    Kiki Chang
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305 5540, USA
    Arch Gen Psychiatry 61:781-92. 2004
    ..Neuroimaging studies of adults with BD have implicated the dorsolateral prefrontal cortex (DLPFC) and anterior cingulate cortex (ACC) in the development of this disorder...
  2. pmc Effect of divalproex on brain morphometry, chemistry, and function in youth at high-risk for bipolar disorder: a pilot study
    Kiki Chang
    Division of Child and Adolescent Psychiatry, Stanford University School of Medicine, Stanford, California 94305 5540, USA
    J Child Adolesc Psychopharmacol 19:51-9. 2009
    ..We sought to examine the effects of divalproex on the structure, chemistry, and function of specific brain regions in children at high-risk for BD...
  3. pmc Brain glutamatergic characteristics of pediatric offspring of parents with bipolar disorder
    Manpreet Singh
    Department of Psychiatry and Behavioral Sciences, Division of Child and Adolescent Psychiatry, Stanford University School of Medicine, 401 Quarry Road, Stanford, CA 94305, USA
    Psychiatry Res 182:165-71. 2010
    ..Longitudinal studies are necessary to confirm whether prefrontal glutamate decreases only after the onset of full mania...
  4. pmc Increased subgenual cingulate cortex volume in pediatric bipolar disorder associated with mood stabilizer exposure
    Myles M Mitsunaga
    Pediatric Bipolar Disorders Program, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305, USA
    J Child Adolesc Psychopharmacol 21:149-55. 2011
    ..We sought to study morphometric characteristics of the SGC in pediatric subjects with familial bipolar disorder (BD) compared with healthy controls...
  5. pmc Neurometabolite effects of response to quetiapine and placebo in adolescents with bipolar depression
    Kiki Chang
    Pediatric Bipolar Disorders Program, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305 5540, USA
    J Child Adolesc Psychopharmacol 22:261-8. 2012
    ..We examined the effects of quetiapine (QUET), an atypical antipsychotic, on these neurochemicals, and potential predictors of response to QUET in adolescents with bipolar depression...
  6. ncbi request reprint Divalproex sodium reduces overall aggression in youth at high risk for bipolar disorder
    Kirti Saxena
    Department of Psychiatry and Behavioral Sciences, Division of Child Psychiatry and Child Development, School of Medicine, Stanford University, 401 Quarry Road, Stanford, CA 94305, USA
    J Child Adolesc Psychopharmacol 16:252-9. 2006
    ..The psychopharmacology of aggression in youth is relatively unexplored, even though such maladaptive aggression manifests across many different diagnoses...
  7. doi request reprint Atomoxetine as an adjunct therapy in the treatment of co-morbid attention-deficit/hyperactivity disorder in children and adolescents with bipolar I or II disorder
    Kiki Chang
    Pediatric Bipolar Disorders Program, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA
    J Child Adolesc Psychopharmacol 19:547-51. 2009
    ..We conducted an 8-week, open label study to study the efficacy and tolerability of adjunct atomoxetine in euthymic children and adolescents with BPD and ADHD...
  8. pmc Subcortical volumetric correlates of anxiety in familial pediatric bipolar disorder: a preliminary investigation
    Diana I Simeonova
    Pediatric Bipolar Disorders Program, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305 5540, USA
    Psychiatry Res 173:113-20. 2009
    ..The overlap between anxiety and familial pediatric BD suggests that anxiety may be one important area of future research in parsing out the heterogeneous nature and complex etiology of early-onset BD...
  9. ncbi request reprint Cortical magnetic resonance imaging findings in familial pediatric bipolar disorder
    Kiki Chang
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA
    Biol Psychiatry 58:197-203. 2005
    ..We studied gray matter volume, ventricular-to-brain ratios (VBR), and number of WMH in patients with familial, pediatric BD compared with control subjects...
  10. doi request reprint The role of the amygdala in bipolar disorder development
    Amy Garrett
    Stanford University School of Medicine, CA 94305, USA
    Dev Psychopathol 20:1285-96. 2008
    ..In addition, evidence is accumulating to suggest that this model has flexible outcomes, depending on factors intrinsic and extrinsic to BD, and may follow several possible paths across the course of maturational development...
  11. ncbi request reprint Divalproex sodium for the treatment of PTSD and conduct disordered youth: a pilot randomized controlled clinical trial
    Hans Steiner
    Division of Child Psychiatry and Child Development, Stanford University School of Medicine, 401 Quarry Road, Stanford, CA 94305 5719, USA
    Child Psychiatry Hum Dev 38:183-93. 2007
    ..Intent-to-treat analyses showed significant positive associations between receiving high dose of DVP CGI's. Parallel analyses comparing outcome by drug level achieved strengthened the results...
  12. ncbi request reprint An open-label study of lamotrigine adjunct or monotherapy for the treatment of adolescents with bipolar depression
    Kiki Chang
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305 5540, USA
    J Am Acad Child Adolesc Psychiatry 45:298-304. 2006
    ..The authors wished to prospectively study the efficacy of lamotrigine as adjunctive or monotherapy in adolescents with bipolar disorder who were experiencing a depressive episode...
  13. ncbi request reprint Baseline predictors of response to divalproex in conduct disorder
    Kirti Saxena
    Department of Psychiatry and Behavioral Sciences, Division of Child Psychiatry and Child Development, Stanford University School of Medicine, 401 Quarry Road, Stanford, CA 94305, USA
    J Clin Psychiatry 66:1541-8. 2005
    ....
  14. pmc Antidepressants and psychostimulants in pediatric populations: is there an association with mania?
    Michelle Goldsmith
    Stanford Pediatric Bipolar Disorders Program, Stanford University School of Medicine, Department of Psychiatry, 401 Quarry Road, Stanford, CA 94305, USA
    Paediatr Drugs 13:225-43. 2011
    ....
  15. ncbi request reprint Decreased N-acetylaspartate in children with familial bipolar disorder
    Kiki Chang
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305, USA
    Biol Psychiatry 53:1059-65. 2003
    ..We used proton magnetic resonance spectroscopy to investigate dorsolateral prefrontal N-acetylaspartate levels in children with familial bipolar disorder...
  16. ncbi request reprint Reduced amygdalar gray matter volume in familial pediatric bipolar disorder
    Kiki Chang
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305 5540, USA
    J Am Acad Child Adolesc Psychiatry 44:565-73. 2005
    ..We sought to study morphometric characteristics of these structures in pediatric subjects with familial BD compared with healthy controls...
  17. ncbi request reprint Will neuroimaging ever be used to diagnose pediatric bipolar disorder?
    Kiki Chang
    Stanford University School of Medicine, CA 94305 5540, USA
    Dev Psychopathol 18:1133-46. 2006
    ....
  18. pmc Challenges in the diagnosis and treatment of pediatric bipolar depression
    Kiki Chang
    Pediatric Bipolar Disorders Program, Stanford University School of Medicine, Stanford, California 94305 5540, USA
    Dialogues Clin Neurosci 11:73-80. 2009
    ....
  19. ncbi request reprint Studies of offspring of parents with bipolar disorder
    Kiki Chang
    Pediatric Mood Disorders Clinic, Stanford University School of Medicine, Stanford, CA 94305, USA
    Am J Med Genet C Semin Med Genet 123:26-35. 2003
    ..The future holds promise for longitudinal studies of bipolar offspring incorporating all of these facets, including genetic analyses, to further elucidate the factors involved in the evolution of BD...
  20. ncbi request reprint Efficacy profiles of psychopharmacology: divalproex sodium in conduct disorder
    Leena A Khanzode
    Division of Child Psychiatry and Child Development, Stanford University School of Medicine, 401 Quarry Road, Stanford, CA 94305 5719, USA
    Child Psychiatry Hum Dev 37:55-64. 2006
    ..This is a rare clinical trial, which provides preliminary evidence for the different profiles of efficacy of medication treatment...
  21. ncbi request reprint Psychopharmacologic strategies for the treatment of aggression in juveniles
    Hans Steiner
    Department of Psychiatry and Behavioral Sciences, Division of Child Psychiatry and Child Development, Stanford University School of Medicine, California 94503, USA
    CNS Spectr 8:298-308. 2003
    ....
  22. ncbi request reprint Adult bipolar disorder is continuous with pediatric bipolar disorder
    Kiki Chang
    Pediatric Bipolar Disorders Program, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Lucile Packard Children s Hospital, California 94305 5540, USA
    Can J Psychiatry 52:418-25. 2007
    ..Prospective studies incorporating phenomenological and biological assessment are needed to decisively address this issue...
  23. ncbi request reprint Prevention of pediatric bipolar disorder: integration of neurobiological and psychosocial processes
    Kiki Chang
    Pediatric Bipolar Disorders Program, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA
    Ann N Y Acad Sci 1094:235-47. 2006
    ..Further research into the biologic and environmental mechanisms of BD development as well as controlled early intervention studies are needed to ameliorate this significant public health problem...
  24. pmc Socio-emotional processing and functioning of youth at high risk for bipolar disorder
    Jane Whitney
    Pediatric Bipolar Disorders Program, Stanford University, Stanford, CA 94305 5540, United States Division of Child and Adolescent Psychiatry, Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305 7298, United States Electronic address
    J Affect Disord 148:112-7. 2013
    ..The goal of this study was to investigate differences in socio-emotional processing and functioning in children and adolescents at high risk for bipolar disorder (BD) and healthy control participants...
  25. ncbi request reprint Divalproex sodium in the treatment of pediatric psychiatric disorders
    Manasi Rana
    Division of Child Psychiatry and Child Development, Department of Psychiatry and Behavioral Sciences, Stanford University, School of Medicine, 401 Quarry Road, Stanford, CA 94305 5719, USA
    Expert Rev Neurother 5:165-76. 2005
    ..In this drug profile, divalproex sodium and its uses in the pediatric population for psychiatric conditions are reviewed...
  26. ncbi request reprint Attention and memory biases in the offspring of parents with bipolar disorder: indications from a pilot study
    Ian H Gotlib
    Stanford University, Stanford, California 94305, USA
    J Child Psychol Psychiatry 46:84-93. 2005
    ..This study examined biases in the processing of emotional stimuli as a potential vulnerability marker of bipolar disorder...
  27. ncbi request reprint Atomoxetine for the treatment of attention-deficit/hyperactivity disorder in children and adolescents with bipolar disorders
    Mina Hah
    Department of Child and Adolescent Psychiatry at Stanford University, Stanford, California 94305 5719, USA
    J Child Adolesc Psychopharmacol 15:996-1004. 2005
    ..Adverse effects of atomoxetine treatment included sedation, nausea, and decreased appetite. These cases suggest that atomoxetine may be a safe and effective treatment for ADHD in conjunction with mood stabilizers in children with BD...
  28. ncbi request reprint Bipolar offspring: a window into bipolar disorder evolution
    Kiki Chang
    Division of Child and Adolescent Psychiatry, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305, USA
    Biol Psychiatry 53:945-51. 2003
    ....
  29. ncbi request reprint Treatment of aggression with risperidone in children and adolescents with bipolar disorder: a case series
    Kirti Saxena
    Department of Psychiatry, Stanford University, Palo Alto, CA 94305, USA
    Bipolar Disord 8:405-10. 2006
    ..To evaluate the effectiveness and safety of risperidone in children and adolescents with bipolar disorder characterized by aggression and mania, despite treatment with mood stabilizers...