MATTHEW E CARTER
Affiliation: Stanford University
- FOXO transcription factorsMATTHEW E CARTER
Department of Genetics and Neurosciences Program, Stanford University, 300 Pasteur Drive, Stanford, California 94305, USA
Curr Biol 17:R113-4. 2007
- Optogenetic investigation of neural circuits in vivoMATTHEW E CARTER
Neurosciences Program and Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA
Trends Mol Med 17:197-206. 2011..Finally, we survey the application of optogenetic tools to studying functional neuroanatomy, behavior and the etiology and treatment of various neurological disorders...
- Shining light on wakefulness and arousalLuis de Lecea
Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA
Biol Psychiatry 71:1046-52. 2012..Here, we discuss the recent results of these experiments and propose future use of this approach as a way to understand the complex dynamics of neural circuits controlling arousal and arousal-related behaviors...
- Mechanism for Hypocretin-mediated sleep-to-wake transitionsMATTHEW E CARTER
Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA
Proc Natl Acad Sci U S A 109:E2635-44. 2012..This coupling of distinct neuronal systems can be generalized to other hypothalamic integrator nuclei with downstream effector/output populations in the brain...
- Tuning arousal with optogenetic modulation of locus coeruleus neuronsMATTHEW E CARTER
Neurosciences Program, Stanford University, Stanford, California, USA
Nat Neurosci 13:1526-33. 2010..These results suggest that the locus coeruleus is finely tuned to regulate organismal arousal and that bursts of noradrenergic overexcitation cause behavioral attacks that resemble those seen in people with neuropsychiatric disorders...
- Sleep homeostasis modulates hypocretin-mediated sleep-to-wake transitionsMATTHEW E CARTER
Neurosciences Program, Stanford University, Palo Alto, California 94304, USA
J Neurosci 29:10939-49. 2009..Collectively, these results suggest that the Hcrt system promotes wakefulness throughout the light/dark period by activating multiple downstream targets, which themselves are inhibited with increased sleep pressure...