Research Topics
| Dennis R CarterSummaryAffiliation: Stanford University Country: USA Publications
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Detail Information
Publications
Modelling cartilage mechanobiologyDennis R Carter
Biomechanical Engineering Division, Mechanical Engineering Department, 215 Durand Building, Stanford University, Stanford, CA 94305, USA
Philos Trans R Soc Lond B Biol Sci 358:1461-71. 2003..As a result, the superficial layer assumes an altered, more fibrous phenotype. These computer model predictions of cartilage mechanobiology are consistent with results of in vitro cell and tissue and molecular biology experiments...
Sutural bone deposition rate and strain magnitude during cranial developmentJames H Henderson
Department of Surgery, Stanford University School of Medicine, Stanford University, Stanford, CA 94305, USA
Bone 34:271-80. 2004....
The pathogenesis of osteoarthritis in cerebral palsyDennis R Carter
Bone and Joint Center of Excellence, VA Palo Alto Health Care System, CA, USA
Dev Med Child Neurol 51:79-83. 2009....
Mechanical strain affects dura mater biological processes: implications for immature calvarial healingKenton D Fong
Department of Surgery, School of Medicine, Stanford University, CA 94305, USA
Plast Reconstr Surg 112:1312-27. 2003..These findings suggest that mechanical strain can induce changes in dura mater biological processes and gene expression that may play important roles in coordinating the growth and healing of the neonatal calvaria...
Hydrostatic pressure enhances chondrogenic differentiation of human bone marrow stromal cells in osteochondrogenic mediumDiane R Wagner
Department of Mechanical Engineering, Stanford University, Stanford, CA, USA
Ann Biomed Eng 36:813-20. 2008....
Dose- and time-dependent effects of cyclic hydrostatic pressure on transforming growth factor-beta3-induced chondrogenesis by adult human mesenchymal stem cells in vitroKeita Miyanishi
Orthopaedic Research Laboratory, Stanford University School of Medicine, Stanford, California 94305-5341, USA
Tissue Eng 12:2253-62. 2006..The data suggest that tissue engineering of articular cartilage through application or recruitment of hMSCs can be facilitated by mechanical stimulation...
Gene regulation ex vivo within a wrap-around tendonKelvin W Li
Bone and Joint Center of Excellence, VA Palo Alto Health Care System, Palo Alto, California 94304, USA
Tissue Eng 12:2611-8. 2006..These differentiation responses begin within as little as 2 h after the onset of mechanical stimulation and may be the basis for the formation of fibrocartilage that is typically found in the wrap-around region of mature tendons in vivo...
A new software tool (VA-BATTS) to calculate bending, axial, torsional and transverse shear stresses within bone cross sections having inhomogeneous material propertiesLampros C Kourtis
Bone and Joint Center of Excellence, VA Palo Alto Health Care System, Palo Alto, CA 94304, USA
Comput Methods Biomech Biomed Engin 11:463-76. 2008....
Mechanobiology of mandibular distraction osteogenesis: experimental analyses with a rat modelElizabeth G Loboa
Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305 5148, USA
Bone 34:336-43. 2004..Taken together, our interpretation of these data is that daily distractions cause daily tissue damage which triggers new mesenchymal tissue formation...
Mechanobiology of mandibular distraction osteogenesis: finite element analyses with a rat modelElizabeth G Loboa
Biomechanical Engineering Division, Mechanical Engineering Department, Stanford University, CA 94305, USA
J Orthop Res 23:663-70. 2005....
New QCT analysis approach shows the importance of fall orientation on femoral neck strengthR Dana Carpenter
Bone and Joint Center, VA Palo Alto Health Care System, Palo Alto, California, USA
J Bone Miner Res 20:1533-42. 2005..A new image analysis technique showed that the strength of the femoral neck in 37 males varied significantly along the neck axis and that bending strength varied by a factor of up to 2.8 for different loading directions...
Age-dependent properties and quasi-static strain in the rat sagittal sutureJames H Henderson
Biomechanical Engineering Division, Mechanical Engineering Department, Stanford University, Stanford, CA 94025 4038, USA
J Biomech 38:2294-301. 2005..The findings show that during development the rat sagittal suture, as a structure, changes significantly and is exposed to quasi-static tensile strain in vivo due to intracranial pressure...
Age-dependent residual tensile strains are present in the dura mater of ratsJames H Henderson
Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305, USA
J R Soc Interface 2:159-67. 2005..64%, p=0.0218). Our findings show that age-dependent residual tensile strains exist in the dura mater of rats. We speculate that these strains may reflect the rate and direction of cranial growth and may also influence cranial healing...
Mechanobiological predictions of growth front morphology in developmental hip dysplasiaSandra J Shefelbine
VA Rehabilitation Research and Development Center, Stanford University, Palo Alto, CA 94305, USA
J Orthop Res 22:346-52. 2004..These findings might help in understanding the etiology and pathology of other developmental bone deformities...
Changes in articular cartilage mechanics with meniscectomy: A novel image-based modeling approach and comparison to patterns of OAJoseph M Haemer
Bone and Joint Center, VA Palo Alto Health Care System, USA
J Biomech 44:2307-12. 2011..Characterizing the changes in cartilage mechanics with meniscectomy and correspondence with observed tissue-level effects may help elucidate the etiology of joint-level degradation seen in osteoarthritis...
Mechanobiological predictions of femoral anteversion in cerebral palsySandra J Shefelbine
Stanford University, VA Rehab Research Center, Palo Alto, CA, USA
Ann Biomed Eng 32:297-305. 2004..These results compare well with observations during skeletalgenesis, in which the anteversion angle decreases rapidly in the first few years of normal growth and may increase in children with CP...
Effects of hydrostatic pressure and transforming growth factor-beta 3 on adult human mesenchymal stem cell chondrogenesis in vitroKeita Miyanishi
Orthopaedic Research Laboratory, Stanford University School of Medicine, Stanford, California 94305-5341, USA
Tissue Eng 12:1419-28. 2006..This study demonstrated adjunctive effects of IHP on TGF-beta 3-induced chondrogenesis and suggests that mechanical loading can facilitate articular cartilage tissue engineering...
Relationships between tissue dilatation and differentiation in distraction osteogenesisElise F Morgan
Biomechanical Engineering Division, Mechanical Engineering Department, Durand Building, Room 215, Stanford University, Stanford, CA 94305, USA
Matrix Biol 25:94-103. 2006..These results are used to suggest experiments that can provide a more mechanistic understanding of the role of tissue dilatation in bone regeneration...
Benefit of single-leaf resection for horizontal meniscus tearJoseph M Haemer
Department of Mechanical Engineering, Stanford University, CA 94305 4038, USA
Clin Orthop Relat Res 457:194-202. 2007..Double-leaf resection in this situation did not change these values substantially, suggesting sparing one leaf offers no benefit over resecting both leaves with extensive horizontal meniscus tears...
Equibiaxial tensile strain affects calvarial osteoblast biologyKenton D Fong
Department of Surgery, Stanford University School of Medicine, 257 Campus Drive, Stanford, CA 94305-5148, USA
J Craniofac Surg 14:348-55. 2003....
A conical-collared intramedullary stem can improve stress transfer and limit micromotionJay A Mandell
Rehabilitation Research and Development Center (153, VA Palo Alto Health Care System, Palo Alto, CA 94304-1200, USA
Clin Biomech (Bristol, Avon) 19:695-703. 2004..Stems with conical collar angles in the range of 30-60 degrees can provide increased stress transfer compared to a flat collar design and reduced micromotion compared to a collarless tapered design...
The low permeability of healthy meniscus and labrum limit articular cartilage consolidation and maintain fluid load support in the knee and hipJoseph M Haemer
Bone and Joint Center, VA Palo Alto Health Care System, USA Department of Mechanical Engineering, Stanford University, USA
J Biomech 45:1450-6. 2012..This may be an important aspect of the role of fibrocartilage in protecting these joints from osteoarthritis...
Articular cartilage friction increases in hip joints after the removal of acetabular labrumYongnam Song
Department of Mechanical Engineering, Korea University, Seoul, Republic of Korea
J Biomech 45:524-30. 2012..Even focal labrectomy may result in increased joint friction, a condition that may be detrimental to articular cartilage and lead to osteoarthritis...
The periosteum as a cellular source for functional tissue engineeringEmily J Arnsdorf
Bone and Joint R and D Center, VA Palo Alto Health Care System, Palo Alto, California, USA
Tissue Eng Part A 15:2637-42. 2009..Thus, this study lays the groundwork for future investigations that will more deeply enumerate the cellular sources and molecular events governing periosteal cell differentiation...
Effects of creep and cyclic loading on the mechanical properties and failure of human Achilles tendonsTishya A L Wren
Rehabilitation Research and Development Center, Veterans Affairs Health Care System, 3801 Miranda Avenue No 153, Palo Alto, CA, USA
Ann Biomed Eng 31:710-7. 2003..The cyclically loaded specimens failed faster than would be expected if only time-dependent damage occurred, suggesting that repetitive loading also contributes to Achilles tendon injuries...
Development of the femoral bicondylar angle in hominid bipedalismS J Shefelbine
Biomechanical Engineering Division, Mechanical Engineering Department, Durand Building Room 215, Stanford University, Palo Alto, CA 94305-4038, USA
Bone 30:765-70. 2002..The mechanobiological relationship between endochondral ossification and mechanical loading provides valuable insight into bone development and morphology...
Failure and fatigue characteristics of adhesive athletic tapeRichard W Bragg
Stanford University, Department of Mechanical Engineering, Biomechanical Engineering Division, Stanford, CA 94305-4038, USA
Med Sci Sports Exerc 34:403-10. 2002..Ultimately, these improved tapes should reduce ankle injuries among athletes...
