Research Topics
Genomes and Genes
Species | Suzan L CarmichaelSummaryAffiliation: Stanford University Country: USA Publications
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Detail Information
Publications
Diacylglycerol kinase K variants impact hypospadias in a California study populationSuzan L Carmichael
Department of Pediatrics, Division of Neonatology, Stanford University School of Medicine, Stanford, California 94305 5415, USA
J Urol 189:305-11. 2013..Our objectives were to determine whether this finding could be replicated in a more racially/ethnically diverse study population of California births and to provide a more comprehensive investigation of variants...
Nutritional factors and hypospadias risksSuzan L Carmichael
Department of Pediatrics, Stanford University, Stanford, CA 94305 5415, USA
Paediatr Perinat Epidemiol 26:353-60. 2012..We examined whether hypospadias was associated with several aspects of the diet, including intake of animal products, intake of several nutrients and food groups related to a vegetarian diet and oestrogen metabolism, and diet quality...
Environmental and genetic contributors to hypospadias: a review of the epidemiologic evidenceSuzan L Carmichael
Department of Pediatrics, Division of Neonatology, Stanford University School of Medicine, California, USA
Birth Defects Res A Clin Mol Teratol 94:499-510. 2012....
Reduced risks of neural tube defects and orofacial clefts with higher diet qualitySuzan L Carmichael
Department of Pediatrics, Stanford University, CA 94305 5415, USA
Arch Pediatr Adolesc Med 166:121-6. 2012..To examine whether better maternal diet quality was associated with reduced risk for selected birth defects...
Estimated dietary phytoestrogen intake and major food sources among women during the year before pregnancySuzan L Carmichael
Department of Pediatrics, Stanford University, Stanford, CA, USA
Nutr J 10:105. 2011..Recently published data on phytoestrogen content of a wide range of foods provide an opportunity to improve estimation of dietary phytoestrogen intake...
Craniosynostosis and nutrient intake during pregnancySuzan L Carmichael
California Research Division, March of Dimes Foundation, Oakland, California, USA
Birth Defects Res A Clin Mol Teratol 88:1032-9. 2010..To examine the association of craniosynostosis with maternal intake of folic acid-containing supplements and dietary nutrients...
Nested case-control study of one-carbon metabolites in mid-pregnancy and risks of cleft lip with and without cleft palateGary M Shaw
Department of Pediatrics, Stanford University School of Medicine, Palo Alto, CA, 94305, USA
Pediatr Res 66:501-6. 2009..These data did not show meaningful differences between cases and controls for any other analytes...
118 SNPs of folate-related genes and risks of spina bifida and conotruncal heart defectsGary M Shaw
Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA, USA
BMC Med Genet 10:49. 2009..Investigations into genetic variation that influences transport and metabolism of folate will help fill this data gap. We focused on 118 SNPs involved in folate transport and metabolism...
Maternal corticosteroid use and hypospadiasSuzan L Carmichael
California Research Division, March of Dimes Foundation, Oakland, CA 94609, USA
J Pediatr 155:39-44, 44.e1. 2009..To explore whether women who reported corticosteroid use during pregnancy were more likely to deliver an infant with hypospadias than women who did not...
Mid-pregnancy cotinine and risks of orofacial clefts and neural tube defectsGary M Shaw
March of Dimes California Research Division, Children s Hospital Oakland Research Institute, Oakland, CA 94609, USA
J Pediatr 154:17-9. 2009..We have correlated measurements of cotinine (a nicotine metabolite) in mid-pregnancy sera with clefts and NTDs...
Periconceptional nutrient intakes and risks of neural tube defects in CaliforniaSuzan L Carmichael
California Research Division, March of Dimes Foundation, Oakland, California 94609 1673, USA
Birth Defects Res A Clin Mol Teratol 88:670-8. 2010....
NTD prevalences in central California before and after folic acid fortificationBrian H Chen
March of Dimes Foundation, California Research Division, Oakland, California 94609, USA
Birth Defects Res A Clin Mol Teratol 82:547-52. 2008..This study examined whether the declining prefortification (1989-1996) NTD prevalences continued into the postfortification period (1998-2003) in selected California counties...
Craniosynostosis and maternal smokingSuzan L Carmichael
March of Dimes Foundation, California Research Division, Oakland, California, USA
Birth Defects Res A Clin Mol Teratol 82:78-85. 2008..Several previous studies suggested increased risk of craniosynostosis among infants born to women who smoked...
Periconceptional glycaemic load and intake of sugars and their association with neural tube defects in offspringGary M Shaw
March of Dimes, California Research Division, Children s Hospital Oakland Research Institute, 5700 Martin Luther King Jr Way, Oakland, CA 94609, USA
Paediatr Perinat Epidemiol 22:514-9. 2008..The reasons for current findings to be inconsistent with previous findings are unknown...
Nutrient pathways and neural tube defects: a semi-Bayesian hierarchical analysisSuzan L Carmichael
California Research Division, March of Dimes Foundation, Children s Hospital Oakland Research Institute, Oakland, CA 94609, USA
Epidemiology 20:67-73. 2009..The hierarchical approach produces more plausible, more stable estimates than the conventional approach, while adjusting for potential confounding by other nutrients...
Hypospadias and intake of nutrients related to one-carbon metabolismSuzan L Carmichael
California Research Division, March of Dimes Foundation, Oakland, California, USA
J Urol 181:315-21; discussion 321. 2009....
Occurrence of low birthweight and preterm delivery among California infants before and after compulsory food fortification with folic acidGary M Shaw
March of Dimes Birth Defects Foundation, California Birth Defects Monitoring Program, Berkeley, CA, USA
Public Health Rep 119:170-3. 2004..S. The objective of this study was to investigate the frequencies of low birthweight and preterm delivery after mandatory folic acid fortification among approximately six million California births...
Maternal stressful life events and risks of birth defectsSuzan L Carmichael
March of Dimes Birth Defect Foundation, California Department of Health Services, California Birth Defects Monitoring Program, Berkeley, CA, USA
Epidemiology 18:356-61. 2007..Several previous studies suggest that maternal stress may be associated with increased risk of certain birth defects. This study examined the association of maternal stressful life events with risks of several birth defects...
Choline and risk of neural tube defects in a folate-fortified populationGary M Shaw
Stanford University School of Medicine, Stanford, California, USA
Epidemiology 20:714-9. 2009..Even so, NTDs continue to occur despite individual supplementation or population fortification with folic acid. We investigated other nutrients related to one-carbon metabolism that may affect NTD risk...
Periconceptional intake of folic acid and food folate and risks of preterm deliveryGary M Shaw
Stanford University School of Medicine, Stanford, California, USA
Am J Perinatol 28:747-52. 2011..Findings suggest some evidence that folates influenced risks; however, an interpretation of results was also consistent with no association between intake of folates and preterm delivery...
Maternal periconceptional alcohol consumption and risk for conotruncal heart defectsSuzan L Carmichael
March of Dimes Birth Defects Foundation/California Department of Health Services, California Birth Defects Monitoring Program, Oakland, California, USA
Birth Defects Res A Clin Mol Teratol 67:875-8. 2003..Most of the risk estimates were imprecise, and chance could not be ruled out as an explanation for the observed findings...
Maternal corticosteroid use and orofacial cleftsSuzan L Carmichael
March of Dimes Foundation California Department of Health Services, California Birth Defects Monitoring Program, Berkeley, CA, USA
Am J Obstet Gynecol 197:585.e1-7; discussion 683-4, e1-7. 2007..The purpose of this study was to examine whether maternal corticosteroid use during pregnancy is associated with delivering an infant with an orofacial cleft...
Association of microtia with maternal obesity and periconceptional folic acid useChen Ma
California Research Division, March of Dimes Foundation, Children s Hospital Oakland Research Institute, 5700 Martin Luther King, Jr Way, Oakland, CA 94609, USA
Am J Med Genet A 152:2756-61. 2010..This analysis suggests that maternal periconceptional intake of folic-acid-containing supplements may provide protection from microtia for non-obese women...
Congenital malformations co-occurring with hypospadias in California, 1983-1997Wei Yang
March of Dimes, California Research Division, Children s Hospital Oakland Research Institute, Oakland, California, USA
Am J Med Genet A 143:2627-34. 2007..Computations were extended to 4-digit level BPA codes. Almost all observed relative risks for malformations co-occurring with hypospadias overall and three subgroups were less than 1...
Markers of acculturation and risk of NTDs among Hispanic women in CaliforniaSuzan L Carmichael
California Research Division, March of Dimes Foundation, Oakland, California 94609, USA
Birth Defects Res A Clin Mol Teratol 82:755-62. 2008..It also examines whether known NTD risk factors explain observed differences in risk among Hispanic women who are more and less acculturated...
Maternal nutrition and gastroschisis: findings from the National Birth Defects Prevention StudyMarcia L Feldkamp
Division of Medical Genetics, Department of Pediatrics, University of Utah, Salt Lake City, USA
Am J Obstet Gynecol 204:404.e1-404.e10. 2011..Gastroschisis is increasing in many countries, especially among young women. Because young women may have inadequate nutrition, we assessed the relationship between individual nutrients and the risk for gastroschisis...
Dieting behaviors and risk of neural tube defectsSuzan L Carmichael
March of Dimes Birth Defects Foundation California Department of Health Services, California Birth Defects Monitoring Program, Oakland, CA, USA
Am J Epidemiol 158:1127-31. 2003..7, 95% confidence interval: 0.7, 10.2). This study suggests that maternal dieting behaviors involving restricted food intake during the first trimester may be associated with increased NTD risk...
Prepregnant obesity and risks of selected birth defects in offspringGary M Shaw
March of Dimes, California Research Division, Children s Hospital Oakland Research Institute, Oakland, CA, USA
Epidemiology 19:616-20. 2008..We investigated the previously observed association between obesity and spina bifida and also possible associations between obesity and other birth defects...
Chromosomal abnormalities among children born with conotruncal cardiac defectsEdward J Lammer
Children s Hospital Oakland Research Institute, Oakland, California 94609, USA
Birth Defects Res A Clin Mol Teratol 85:30-5. 2009..This study describes the frequency of chromosome abnormalities and microdeletion of 22q11 associated among infants and fetuses delivered with conotruncal heart malformations...
Periconceptional nutrient intakes and risks of conotruncal heart defectsGary M Shaw
Stanford University School of Medicine, Stanford, California 94305, USA
Birth Defects Res A Clin Mol Teratol 88:144-51. 2010..We investigated the observed association between conotruncal heart defects and periconceptional vitamin use, as well as potential associations with other dietary nutrients...
Trends in the probability of twins and males in California, 1983-2003Jill Hardin
March of Dimes, California Research Division, Children s Hospital Oakland Research Institute, Oakland, California 94609, United States of America
Twin Res Hum Genet 12:93-102. 2009..The cause of the increase in twins is unknown but coincides with trends towards delayed childbearing and increased use of subfertility treatments...
Prepregnancy obesity: a complex risk factor for selected birth defectsSuzan L Carmichael
California Research Division, March of Dimes Foundation, 5700 Martin Luther King, Jr Way, Oakland, CA 94609, USA
Birth Defects Res A Clin Mol Teratol 88:804-10. 2010....
Congenital malformations in births with orofacial clefts among 3.6 million California births, 1983-1997Gary M Shaw
March of Dimes Birth Defects Foundation, California Birth Defects Monitoring Program, Oakland, California 94710, USA
Am J Med Genet A 125:250-6. 2004..These observed patterns tended to be similar for CP and for CLP...
Limb deficiency defects, MSX1, and exposure to tobacco smokeSuzan L Carmichael
March of Dimes Birth Defect Foundation California Department of Health Services, California Birth Defects Monitoring Program, Oakland, California 94710, USA
Am J Med Genet A 125:285-9. 2004..This finding contrasts with results of a previous study, which provided initial evidence for such an interaction. Several important methodological differences may have contributed to the differences in findings between the two studies...
Socio-economic status and risk of conotruncal heart defects and orofacial cleftsSuzan L Carmichael
March of Dimes Birth Defects Foundation California Department of Health Services, California Birth Defects Monitoring Program, Oakland, CA 94710, USA
Paediatr Perinat Epidemiol 17:264-71. 2003..4 for dTGA, and ORs for all six measures were < 0.7 for TOF. ORs for clefts tended to be closer to 1. This study suggests that SES risks are birth defect specific...
Nutrient intakes in women and risks of anophthalmia and microphthalmia in their offspringGary M Shaw
March of Dimes Birth Defects Foundation, California Research Division, Oakland, California, USA
Birth Defects Res A Clin Mol Teratol 79:708-13. 2007..In this population-based case-control study we investigated whether periconceptional intakes of supplemental folic acid, dietary folate, vitamin A, and several other nutrients were associated with these eye defects...
Food fortification with folic acid and twinning among California infantsGary M Shaw
March of Dimes Birth Defects Foundation, California Birth Defects Monitoring Program, Oakland, California 94606, USA
Am J Med Genet A 119:137-40. 2003..Our results do not suggest a change in twinning prevalence associated with folic acid fortification of the US food supply among women delivering in California...
Socioeconomic measures, orofacial clefts, and conotruncal heart defects in CaliforniaSuzan L Carmichael
California Research Division, March of Dimes Foundation, Oakland, California 94609, USA
Birth Defects Res A Clin Mol Teratol 85:850-7. 2009..To examine the association of multiple measures of socioeconomic status (SES) with risks of orofacial clefts and conotruncal heart defects...
Hypospadias in California: trends and descriptive epidemiologySuzan L Carmichael
March of Dimes Birth Defect Foundation, California Birth Defects Monitoring Program, Oakland, California, USA
Epidemiology 14:701-6. 2003..We used actively ascertained, population-based data for which detailed clinical descriptions permitted careful phenotypic classifications...
Maternal food insecurity is associated with increased risk of certain birth defectsSuzan L Carmichael
March of Dimes Foundation, California Birth Defects Monitoring Program, Berkeley, CA 94710, USA
J Nutr 137:2087-92. 2007..e. 2), the corresponding OR was 1.16 (95% CI 0.96, 1.38). This study suggests that increased risks of certain birth defects may be included among the negative consequences of food insecurity...
Nutrient intakes in women and congenital diaphragmatic hernia in their offspringWei Yang
March of Dimes, California Research Division, Oakland, California 94609, USA
Birth Defects Res A Clin Mol Teratol 82:131-8. 2008..The etiologies of CDH remain unknown, although experimental animal data suggest dietary factors might play a role. This study examined whether maternal nutrient intakes were associated with delivering infants with CDH...
Considering the vascular hypothesis for the pathogenesis of small intestinal atresia: a case control study of genetic factorsTanya Gupta
University of California San Diego School of Medicine, La Jolla, CA, USA
Am J Med Genet A 161:702-10. 2013..These results also identify genes meriting further exploration in SIA studies. Hence, this study makes an important contribution by exploring the long-held but not well-investigated vascular hypothesis...
Thymidylate synthase polymorphisms and risks of human orofacial cleftsGary M Shaw
Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
Birth Defects Res A Clin Mol Teratol 97:95-100. 2013..We investigated effect measure modification between these variants and maternal folate intake for cleft risk...
Association of microtia with maternal nutritionChen Ma
Department of Pediatrics, Stanford University, Stanford, California
Birth Defects Res A Clin Mol Teratol 94:1026-32. 2012..Few studies have investigated the potential association of maternal dietary intake and risk of microtia among offspring...
Cancer in children with nonchromosomal birth defectsPaul Graham Fisher
Department of Neurology, Stanford University, Palo Alto, CA, USA
J Pediatr 160:978-83. 2012..To examine whether the incidence of childhood cancer is elevated in children with birth defects but no chromosomal anomalies...
Association between 49 infant gene polymorphisms and preterm deliveryBrian H Chen
California Birth Defects Monitoring Program, March of Dimes Foundation, Berkeley, California 94710, USA
Am J Med Genet A 143:1990-6. 2007..4, 95% CI = 0.2-0.8). This finding suggests the coagulation/thrombophilic pathway may influence the development of preterm delivery...
Epidemiologic characteristics of anotia and microtia in California, 1989-1997Gary M Shaw
March of Dimes Birth Defects Foundation, California Birth Defects Monitoring Program, Berkeley, California, USA
Birth Defects Res A Clin Mol Teratol 70:472-5. 2004..There is a paucity of epidemiologic information about the external ear malformations anotia and microtia...
Timing of prenatal care initiation and risk of congenital malformationsSuzan L Carmichael
March of Dimes Birth Defect Foundation, California Birth Defects Monitoring Program, Oakland, California 94606, USA
Teratology 66:326-30. 2002..This study uses data from a large population-based registry to explore the association of timing of prenatal care initiation with risks of selected congenital malformation phenotypes...
Maternal periconceptional vitamins: interactions with selected factors and congenital anomalies?Gary M Shaw
March of Dimes Birth Defects Foundation, California Birth Defects Monitoring Program, Oakland, California 94606, USA
Epidemiology 13:625-30. 2002..We hypothesized that effects of congenital anomalies associated with maternal fever, cigarette smoking or alcohol use would be modified by intake of vitamins...
Hypospadias and halogenated organic pollutant levels in maternal mid-pregnancy serum samplesSuzan L Carmichael
California Research Division, March of Dimes Foundation, Oakland, CA 94609, USA
Chemosphere 80:641-6. 2010..Environmental contaminants that disrupt endocrine function may contribute to hypospadias etiology...
Association between weight gain during pregnancy and neural tube defects and gastroschisis in offspringWei Yang
Department of Pediatrics, Stanford University, Stanford, California, USA
Birth Defects Res A Clin Mol Teratol 94:1019-25. 2012..The objective of this study was to investigate the association of maternal weight gain with neural tube defects (NTDs) and gastroschisis among offspring...
Social networks and risk of neural tube defectsSuzan L Carmichael
March of Dimes Birth Defects Foundation California Department of Health Services, California Birth Defects Monitoring Program, Oakland, CA 94606 5226, USA
Eur J Epidemiol 18:129-33. 2003..This study is the first to investigate the association between social networks and risk of NTDs. Stronger inferences await replication and extension of these results...
The estimated probability of dizygotic twins: a comparison of two methodsJill Hardin
March of Dimes, California Research Division, Children s Hospital Oakland Research Institute, Oakland, California 94609, United States of America
Twin Res Hum Genet 12:79-85. 2009..Using the above general maximum likelihood estimate, the probability of a dizygotic twin is subject to substantial variation that is largely a function of twin data ascertainment method...
Congenital malformations in offspring of Vietnamese women in California, 1985-97Gary M Shaw
March of Dimes Birth Defects Foundation, California Birth Defects Monitoring Program, Oakland, California 94606, USA
Teratology 65:121-4. 2002..Little is known about reproductive outcome risks for Vietnamese women delivering infants and fetuses in the U.S...
