Affiliation: Stanford University
- On the interactions of the hypothalamic-pituitary-adrenal (HPA) axis and sleep: normal HPA axis activity and circadian rhythm, exemplary sleep disordersTheresa M Buckley
Stanford Sleep Disorders Clinic and Research Center and Department of Psychiatry, Stanford University, 401 Quarry Road, Suite 3301, Stanford, California 94305, USA
J Clin Endocrinol Metab 90:3106-14. 2005..Mechanisms by which cortisol can affect slow wave sleep are discussed, as is the role the HPA axis plays in secondary effects of primary sleep disorders...
- Aging and the role of the HPA axis and rhythm in sleep and memory-consolidationTheresa M Buckley
Stanford Sleep Disorders Clinic and Research Center TMB, Stanford, CA, USA
Am J Geriatr Psychiatry 13:344-52. 2005..In this regard, the authors propose that drugs that act directly on the HPA axis (e.g., mineralocorticoid agonists) may be potentially quite useful for improving both sleep and declarative memory consolidation during sleep...
- The acute effects of a mineralocorticoid receptor (MR) agonist on nocturnal hypothalamic-adrenal-pituitary (HPA) axis activity in healthy controlsTheresa M Buckley
Department of Psychiatry and Behavioral Sciences, Stanford University Medical School, CA 94301, USA
Psychoneuroendocrinology 32:859-64. 2007..Herein, we propose that an MR agonist may inhibit the HPA axis without first "unloading" receptors of endogenous cortisol...
- The acute and post-discontinuation effects of a glucocorticoid receptor (GR) antagonist probe on sleep and the HPA axis in chronic insomnia: a pilot studyTheresa Buckley
Department of Psychiatry, Stanford University Medical School, Stanford, CA, USA
J Clin Sleep Med 4:235-41. 2008..Aglucocorticoid receptor (GR) antagonist may re-regulate HPA axis activity even after discontinuation and may have clinical benefit...
- A pilot study of the phase angle between cortisol and melatonin in major depression - a potential biomarker?Theresa M Buckley
Dept of Psychiatry and Behavioral Sciences, Stanford University Medical School, 401 Quarry Road, Stanford, CA 94305 5730, United States
J Psychiatr Res 44:69-74. 2010..In this pilot study, we link cortisol and melatonin rhythms and propose that the phase angle between cortisol acrophase (CA) and dim-light melatonin onset (20 pg/ml) (DLMO-20) may yield a useful state specific biomarker for MDD...