Research Topics
| Patrick O BrownSummaryAffiliation: Stanford University Country: USA Publications
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Detail Information
Publications
The preclinical natural history of serous ovarian cancer: defining the target for early detectionPatrick O Brown
Department of Biochemistry, Stanford University School of Medicine, Stanford, California, USA
PLoS Med 6:e1000114. 2009..We can learn about this occult period by studying the unsuspected serous cancers that are discovered in a small fraction of apparently healthy women who undergo prophylactic bilateral salpingo-oophorectomy (PBSO)...
ESRRA-C11orf20 is a recurrent gene fusion in serous ovarian carcinomaJulia Salzman
Department of Biochemistry, Stanford University School of Medicine, Stanford, California, USA
PLoS Biol 9:e1001156. 2011..Gene fusions involving adjacent or nearby genes can readily escape detection but may play important roles in the development and progression of cancer...
Circular RNAs are the predominant transcript isoform from hundreds of human genes in diverse cell typesJulia Salzman
Department of Biochemistry, Stanford University School of Medicine, Stanford, California, United States of America
PLoS ONE 7:e30733. 2012..Our results suggest that a non-canonical mode of RNA splicing, resulting in a circular RNA isoform, is a general feature of the gene expression program in human cells...
The yeast Rab GTPase Ypt1 modulates unfolded protein response dynamics by regulating the stability of HAC1 RNANikoleta G Tsvetanova
Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA
PLoS Genet 8:e1002862. 2012..Our findings establish that Ypt1 contributes to regulation of UPR signaling dynamics by promoting the decay of HAC1 RNA, suggesting a potential regulatory mechanism for linking vesicle trafficking to the UPR and ER homeostasis...
Widespread mRNA association with cytoskeletal motor proteins and identification and dynamics of myosin-associated mRNAs in S. cerevisiaeJason M Casolari
Department of Biochemistry, Stanford University School of Medicine, Stanford, California, United States of America
PLoS ONE 7:e31912. 2012....
