Patrick O Brown

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc The preclinical natural history of serous ovarian cancer: defining the target for early detection
    Patrick O Brown
    Department of Biochemistry, Stanford University School of Medicine, Stanford, California, USA
    PLoS Med 6:e1000114. 2009
  2. pmc Improved discovery of molecular interactions in genome-scale data with adaptive model-based normalization
    Julia Salzman
    Department of Biochemistry, Stanford University School of Medicine, Stanford, California, USA
    PLoS ONE 8:e53930. 2013
  3. pmc Cell-type specific features of circular RNA expression
    Julia Salzman
    Department of Biochemistry, Stanford University School of Medicine, Stanford, California, United States of America
    PLoS Genet 9:e1003777. 2013
  4. pmc ESRRA-C11orf20 is a recurrent gene fusion in serous ovarian carcinoma
    Julia Salzman
    Department of Biochemistry, Stanford University School of Medicine, Stanford, California, USA
    PLoS Biol 9:e1001156. 2011
  5. pmc Circular RNAs are the predominant transcript isoform from hundreds of human genes in diverse cell types
    Julia Salzman
    Department of Biochemistry, Stanford University School of Medicine, Stanford, California, United States of America
    PLoS ONE 7:e30733. 2012
  6. pmc Quantitative proteomic analysis reveals concurrent RNA-protein interactions and identifies new RNA-binding proteins in Saccharomyces cerevisiae
    Daniel M Klass
    Department of Biochemistry, Stanford University School of Medicine, Stanford, California 94305, USA
    Genome Res 23:1028-38. 2013
  7. pmc The yeast Rab GTPase Ypt1 modulates unfolded protein response dynamics by regulating the stability of HAC1 RNA
    Nikoleta G Tsvetanova
    Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA
    PLoS Genet 8:e1002862. 2012
  8. pmc Widespread mRNA association with cytoskeletal motor proteins and identification and dynamics of myosin-associated mRNAs in S. cerevisiae
    Jason M Casolari
    Department of Biochemistry, Stanford University School of Medicine, Stanford, California, United States of America
    PLoS ONE 7:e31912. 2012

Collaborators

Detail Information

Publications8

  1. pmc The preclinical natural history of serous ovarian cancer: defining the target for early detection
    Patrick O Brown
    Department of Biochemistry, Stanford University School of Medicine, Stanford, California, USA
    PLoS Med 6:e1000114. 2009
    ..We can learn about this occult period by studying the unsuspected serous cancers that are discovered in a small fraction of apparently healthy women who undergo prophylactic bilateral salpingo-oophorectomy (PBSO)...
  2. pmc Improved discovery of molecular interactions in genome-scale data with adaptive model-based normalization
    Julia Salzman
    Department of Biochemistry, Stanford University School of Medicine, Stanford, California, USA
    PLoS ONE 8:e53930. 2013
    ....
  3. pmc Cell-type specific features of circular RNA expression
    Julia Salzman
    Department of Biochemistry, Stanford University School of Medicine, Stanford, California, United States of America
    PLoS Genet 9:e1003777. 2013
    ..These results suggest that biogenesis of circular RNA is an integral, conserved, and regulated feature of the gene expression program. ..
  4. pmc ESRRA-C11orf20 is a recurrent gene fusion in serous ovarian carcinoma
    Julia Salzman
    Department of Biochemistry, Stanford University School of Medicine, Stanford, California, USA
    PLoS Biol 9:e1001156. 2011
    ..Gene fusions involving adjacent or nearby genes can readily escape detection but may play important roles in the development and progression of cancer...
  5. pmc Circular RNAs are the predominant transcript isoform from hundreds of human genes in diverse cell types
    Julia Salzman
    Department of Biochemistry, Stanford University School of Medicine, Stanford, California, United States of America
    PLoS ONE 7:e30733. 2012
    ..Our results suggest that a non-canonical mode of RNA splicing, resulting in a circular RNA isoform, is a general feature of the gene expression program in human cells...
  6. pmc Quantitative proteomic analysis reveals concurrent RNA-protein interactions and identifies new RNA-binding proteins in Saccharomyces cerevisiae
    Daniel M Klass
    Department of Biochemistry, Stanford University School of Medicine, Stanford, California 94305, USA
    Genome Res 23:1028-38. 2013
    ..While existing methods can identify sets of RBPs that interact with common RNA targets, our approach can determine which of those interactions are concurrent-a crucial distinction for understanding post-transcriptional regulation...
  7. pmc The yeast Rab GTPase Ypt1 modulates unfolded protein response dynamics by regulating the stability of HAC1 RNA
    Nikoleta G Tsvetanova
    Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA
    PLoS Genet 8:e1002862. 2012
    ..Our findings establish that Ypt1 contributes to regulation of UPR signaling dynamics by promoting the decay of HAC1 RNA, suggesting a potential regulatory mechanism for linking vesicle trafficking to the UPR and ER homeostasis...
  8. pmc Widespread mRNA association with cytoskeletal motor proteins and identification and dynamics of myosin-associated mRNAs in S. cerevisiae
    Jason M Casolari
    Department of Biochemistry, Stanford University School of Medicine, Stanford, California, United States of America
    PLoS ONE 7:e31912. 2012
    ....