Edward S Boyden
Affiliation: Stanford University
- Cerebellum-dependent learning: the role of multiple plasticity mechanismsEdward S Boyden
Department of Neurobiology, Stanford University, Stanford, California 94305, USA
Annu Rev Neurosci 27:581-609. 2004..These principles emerging from studies of the VOR are consistent with results concerning more complex behaviors and thus may reflect general principles of cerebellar function...
- Selective engagement of plasticity mechanisms for motor memory storageEdward S Boyden
Department of Neurobiology, Stanford University, California 94305, USA
Neuron 51:823-34. 2006..Thus, a particular plasticity mechanism need not support all cerebellum-dependent memories, but can be engaged selectively according to the parameters of training...
- Distinct patterns of stimulus generalization of increases and decreases in VOR gainRhea R Kimpo
Dept of Neurobiology, Stanford University, 299 W Campus Dr, Stanford, CA 94305 5125, USA
J Neurophysiol 94:3092-100. 2005..At one or more sites, the plasticity mechanisms supporting decreases in VOR gain must be less synapse-specific, or affect neurons more broadly tuned for head rotation frequency, than the mechanisms supporting increases in gain...
- Active reversal of motor memories reveals rules governing memory encodingEdward S Boyden
Department of Neurobiology, Stanford University, Stanford, CA 94305, USA
Neuron 39:1031-42. 2003..Contrary to previous models about memory encoding by the cerebellum, our results indicate that these behavioral changes are implemented by different plasticity mechanisms, which reverse each other with unequal efficacy...
- Channelrhodopsin-2 and optical control of excitable cellsFeng Zhang
Department of Bioengineering, Clark Center, Stanford University, 318 Campus Drive West, Stanford, California 94305, USA
Nat Methods 3:785-92. 2006..Here we explore technological issues relevant to the temporal precision, spatial targeting and physiological implementation of ChR2, in the context of other photostimulation approaches to optical control of excitable cells...
- Anti-Ca2+ channel antibody attenuates Ca2+ currents and mimics cerebellar ataxia in vivoYaping Joyce Liao
Departments of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA
Proc Natl Acad Sci U S A 105:2705-10. 2008..Our data support the hypothesis that anti-VGCC antibody may play a significant role in the pathogenesis of cerebellar dysfunction in PCA...
- Millisecond-timescale, genetically targeted optical control of neural activityEdward S Boyden
Department of Bioengineering, Stanford University, 318 Campus Drive West, Stanford, California 94305, USA
Nat Neurosci 8:1263-8. 2005..This technology allows the use of light to alter neural processing at the level of single spikes and synaptic events, yielding a widely applicable tool for neuroscientists and biomedical engineers...