- A double-blind, randomized comparison of i.v. lorazepam versus midazolam for sedation of ICU patients via a pharmacologic modelJ Barr
VA Palto Alto Health Care System, Stanford University School of Medicine, Anesthesiology Service, California 94304, USA
Anesthesiology 95:286-98. 2001..The aim of the current study was to characterize and compare the pharmacokinetics and pharmacodynamics of lorazepam and midazolam administered as continuous intravenous infusions for postoperative sedation of surgical ICU patients...
- Propofol dosing regimens for ICU sedation based upon an integrated pharmacokinetic-pharmacodynamic modelJ Barr
Department of Anesthesia, Stanford University, VA Palo Alto Health Care System, California 94304, USA
Anesthesiology 95:324-33. 2001..The aim of the study was to develop propofol dosing guidelines for ICU sedation based on an integrated pharmacokinetic-pharmacodynamic model of propofol infusions in ICU patients...