Samuel Bandara

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. doi Design of experiments to investigate dynamic cell signaling models
    Samuel Bandara
    Chemical and Systems Biology, Stanford University Medical Center, Stanford, CA, USA
    Methods Mol Biol 880:109-18. 2012
  2. pmc Optimal experimental design for parameter estimation of a cell signaling model
    Samuel Bandara
    Department of Chemical and Systems Biology, Stanford University, Stanford, California, USA
    PLoS Comput Biol 5:e1000558. 2009
  3. pmc Regulators of calcium homeostasis identified by inference of kinetic model parameters from live single cells perturbed by siRNA
    Samuel Bandara
    Department of Chemical and Systems Biology, Stanford University, Stanford, CA 94305, USA
    Sci Signal 6:ra56. 2013
  4. ncbi Neuropilin-2 contributes to tumorigenicity in a mouse model of Hedgehog pathway medulloblastoma
    Melanie G Hayden Gephart
    Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA
    J Neurooncol 115:161-8. 2013

Collaborators

  • Tobias Meyer
  • Roland Eils
  • Melanie G Hayden Gephart
  • YouRong Sophie Su
  • Matthew P Scott
  • Feng Chiao Tsai
  • Nicholas Conley
  • Helen Rayburn
  • Jennifer Hong
  • Ljiljana Milenkovic

Detail Information

Publications4

  1. doi Design of experiments to investigate dynamic cell signaling models
    Samuel Bandara
    Chemical and Systems Biology, Stanford University Medical Center, Stanford, CA, USA
    Methods Mol Biol 880:109-18. 2012
    ..Both are treated as optimal control problems in which rapid pharmacological perturbation schemes are identified in silico in order to close an experimental cycle from modeling back to the laboratory bench...
  2. pmc Optimal experimental design for parameter estimation of a cell signaling model
    Samuel Bandara
    Department of Chemical and Systems Biology, Stanford University, Stanford, California, USA
    PLoS Comput Biol 5:e1000558. 2009
    ..Thus, optimal experimental design proved to be a powerful strategy to minimize the number of experiments needed to infer biological parameters from a cell signaling assay...
  3. pmc Regulators of calcium homeostasis identified by inference of kinetic model parameters from live single cells perturbed by siRNA
    Samuel Bandara
    Department of Chemical and Systems Biology, Stanford University, Stanford, CA 94305, USA
    Sci Signal 6:ra56. 2013
    ..Thus, functions of signaling proteins and dynamic regulatory connections can be identified by extracting molecular parameter values from single-cell, time-course data. ..
  4. ncbi Neuropilin-2 contributes to tumorigenicity in a mouse model of Hedgehog pathway medulloblastoma
    Melanie G Hayden Gephart
    Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA
    J Neurooncol 115:161-8. 2013
    ..Knocking down Nrp2 specifically in MB cells avoided any direct effect on tumor vascularization. Nrp2 should be further investigated as a potential target for adjuvant therapy in patients with MB...