Samuel Bandara

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc Optimal experimental design for parameter estimation of a cell signaling model
    Samuel Bandara
    Department of Chemical and Systems Biology, Stanford University, Stanford, California, USA
    PLoS Comput Biol 5:e1000558. 2009
  2. pmc Dynamic recruitment of the curvature-sensitive protein ArhGAP44 to nanoscale membrane deformations limits exploratory filopodia initiation in neurons
    Milos Galic
    Department of Chemical and Systems Biology, Stanford University, Stanford, United States
    elife 3:e03116. 2014
  3. doi request reprint Design of experiments to investigate dynamic cell signaling models
    Samuel Bandara
    Chemical and Systems Biology, Stanford University Medical Center, Stanford, CA, USA
    Methods Mol Biol 880:109-18. 2012
  4. doi request reprint Neuropilin-2 contributes to tumorigenicity in a mouse model of Hedgehog pathway medulloblastoma
    Melanie G Hayden Gephart
    Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA
    J Neurooncol 115:161-8. 2013
  5. pmc Regulators of calcium homeostasis identified by inference of kinetic model parameters from live single cells perturbed by siRNA
    Samuel Bandara
    Department of Chemical and Systems Biology, Stanford University, Stanford, CA 94305, USA
    Sci Signal 6:ra56. 2013
  6. ncbi request reprint Robust neuronal symmetry breaking by Ras-triggered local positive feedback
    Marc Fivaz
    Clark Center, Bio X, Department of Chemical and Systems Biology, Stanford University, 318 Campus Drive, Stanford, California 94305, USA
    Curr Biol 18:44-50. 2008

Collaborators

Detail Information

Publications6

  1. pmc Optimal experimental design for parameter estimation of a cell signaling model
    Samuel Bandara
    Department of Chemical and Systems Biology, Stanford University, Stanford, California, USA
    PLoS Comput Biol 5:e1000558. 2009
    ..Thus, optimal experimental design proved to be a powerful strategy to minimize the number of experiments needed to infer biological parameters from a cell signaling assay...
  2. pmc Dynamic recruitment of the curvature-sensitive protein ArhGAP44 to nanoscale membrane deformations limits exploratory filopodia initiation in neurons
    Milos Galic
    Department of Chemical and Systems Biology, Stanford University, Stanford, United States
    elife 3:e03116. 2014
    ..Together, our data reveals a local auto-regulatory mechanism that limits initiation of filopodia via protein recruitment to nanoscale membrane deformations. ..
  3. doi request reprint Design of experiments to investigate dynamic cell signaling models
    Samuel Bandara
    Chemical and Systems Biology, Stanford University Medical Center, Stanford, CA, USA
    Methods Mol Biol 880:109-18. 2012
    ..Both are treated as optimal control problems in which rapid pharmacological perturbation schemes are identified in silico in order to close an experimental cycle from modeling back to the laboratory bench...
  4. doi request reprint Neuropilin-2 contributes to tumorigenicity in a mouse model of Hedgehog pathway medulloblastoma
    Melanie G Hayden Gephart
    Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA
    J Neurooncol 115:161-8. 2013
    ..Knocking down Nrp2 specifically in MB cells avoided any direct effect on tumor vascularization. Nrp2 should be further investigated as a potential target for adjuvant therapy in patients with MB...
  5. pmc Regulators of calcium homeostasis identified by inference of kinetic model parameters from live single cells perturbed by siRNA
    Samuel Bandara
    Department of Chemical and Systems Biology, Stanford University, Stanford, CA 94305, USA
    Sci Signal 6:ra56. 2013
    ..Thus, functions of signaling proteins and dynamic regulatory connections can be identified by extracting molecular parameter values from single-cell, time-course data. ..
  6. ncbi request reprint Robust neuronal symmetry breaking by Ras-triggered local positive feedback
    Marc Fivaz
    Clark Center, Bio X, Department of Chemical and Systems Biology, Stanford University, 318 Campus Drive, Stanford, California 94305, USA
    Curr Biol 18:44-50. 2008
    ....