Kondala R Atkuri
Affiliation: Stanford University
- Culturing at atmospheric oxygen levels impacts lymphocyte functionKondala R Atkuri
Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305 5318, USA
Proc Natl Acad Sci U S A 102:3756-9. 2005....
- N-Acetylcysteine--a safe antidote for cysteine/glutathione deficiencyKondala R Atkuri
Department of Genetics, School of Medicine, Stanford University, B007 Beckman Center, 279 Campus Drive, Stanford University, CA 94305 5318, United States
Curr Opin Pharmacol 7:355-9. 2007....
- Importance of culturing primary lymphocytes at physiological oxygen levelsKondala R Atkuri
Departments of Genetics and Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA
Proc Natl Acad Sci U S A 104:4547-52. 2007..Thus, we suggest caution in culturing primary lymphocytes at atmosO(2) because the requisite adaptation to nonphysiological oxygen levels may seriously skew T cell responses, particularly after several days in culture...
- Inherited disorders affecting mitochondrial function are associated with glutathione deficiency and hypocitrullinemiaKondala R Atkuri
Department of Genetics, Stanford University, Stanford, CA 94305, USA
Proc Natl Acad Sci U S A 106:3941-5. 2009..Furthermore, studies here suggest that antioxidant therapy may be useful for relieving the chronic oxidative stress that otherwise occurs in patients with mitochondrial dysfunction...
- MYC can induce DNA breaks in vivo and in vitro independent of reactive oxygen speciesSuma Ray
Division of Oncology, Department of Medicine and Pathology, Stanford University School of Medicine, 269 Campus Drive, Stanford, CA 94305, USA
Cancer Res 66:6598-605. 2006..Hence, MYC overexpression can induce ROS and SSBs under some conditions, but generally induces widespread DSBs in vivo and in vitro independent of ROS production...
- Wnt signaling in the thymus is regulated by differential expression of intracellular signaling moleculesFloor Weerkamp
Department of Immunology, Erasmus MC, University Medical Center Rotterdam, The Netherlands
Proc Natl Acad Sci U S A 103:3322-6. 2006..Thus, responsiveness to developmental signals can be regulated by differential expression of intracellular mediators rather than by abundance of receptors or ligands...