Research Topics
| Gabriel AmirSummaryAffiliation: Stanford University Country: USA Publications
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Detail Information
Publications
Improved viability and reduced apoptosis in sub-zero 21-hour preservation of transplanted rat hearts using anti-freeze proteinsGabriel Amir
Heart Transplantation Unit, Department of Cardiac Surgery, Sheba Medical Center, Tel Hashomer, Israel
J Heart Lung Transplant 24:1915-29. 2005..We sought to evaluate and compare the effects of prolonged sub-zero cryopreservation of transplanted rat hearts using AFP I or AFP III...
Neonatal brain protection and deep hypothermic circulatory arrest: pathophysiology of ischemic neuronal injury and protective strategiesGabriel Amir
Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, California 94305, USA
Ann Thorac Surg 80:1955-64. 2005..Surgical techniques consist of intermittent cerebral perfusion during periods of circulatory arrest and continuous regional brain perfusion...
Subzero nonfreezing cryopresevation of rat hearts using antifreeze protein I and antifreeze protein IIIGabriel Amir
Department of Cardiac Surgery, Sheba Medical Center, Tel Hashomer, Israel
Cryobiology 48:273-82. 2004..4 vs. 1.7, p<0.05, and 3.4 vs. 1.7, p<0.05, respectively). In conclusion, AFPs were found to protect the heart from freezing and improve survival and dP (AFP III) in prolonged subzero preservation...
Prolonged 24-hour subzero preservation of heterotopically transplanted rat hearts using antifreeze proteins derived from arctic fishGabriel Amir
Heart Transplantation Unit, Department of Cardiac Surgery, Sheba Medical Center, Tel Hashomer, Israel
Ann Thorac Surg 77:1648-55. 2004..We report 24-hour storage of mammalian hearts for transplantation at subzero temperatures using AFPs derived from arctic fish...
Visual light spectroscopy reflects flow-related changes in brain oxygenation during regional low-flow perfusion and deep hypothermic circulatory arrestGabriel Amir
Division of Pediatric Cardiac Surgery, LPCH, Stanford Medical Center, Stanford, Calif, USA
J Thorac Cardiovasc Surg 132:1307-13. 2006..We used visible light spectroscopy to follow deep and superficial brain SgvO2 during cardiopulmonary bypass, regional low-flow perfusion, and deep hypothermic circulatory arrest...
Evaluation of a peritoneal-generated cardiac patch in a rat model of heterotopic heart transplantationGabriel Amir
Neufeld Cardiac Research Institute, Sheba Medical Center, Tel Aviv University, Tel Hashomer, Israel
Cell Transplant 18:275-82. 2009..Our study also offers a viable rat model for screening and evaluating new concepts in cardiac reconstruction and engineering...
Deep brain hyperthermia while rewarming from hypothermic circulatory arrestGabriel Amir
Department of Cardiothoracic Surgery, Pediatric Division, Schneider Children s Medical Center of Israel, Rabin Medical Center, Petach Tikva, Israel
J Card Surg 24:606-10. 2009..The use of core temperature as the reference point through CPB assumes parallel changes in brain temperature. We tested the hypothesis that regional and deep brain temperature (DBT) differ during cooling, DHCA, and rewarming...
Dynamics of human myocardial progenitor cell populations in the neonatal periodGabriel Amir
Department of Cardiothoracic Surgery, Pediatric Division, Stanford University School of Medicine, Stanford, California 94305 5407, USA
Ann Thorac Surg 86:1311-9. 2008..Our study goals were to identify and quantitate populations of progenitor cells in human neonatal myocardium during the early postnatal period and determine the proliferative capacity of differentiated cardiac myocytes...
Esophageal saturation during antegrade cerebral perfusion: a preliminary report using visible light spectroscopyCarly Heninger
Stanford School of Medicine, Stanford, CA 94305, USA
Paediatr Anaesth 16:1133-7. 2006..CONCLUSIONS: Antegrade cerebral perfusion maintains cerebral oxygen delivery, however, it does not adequately perfuse the esophagus in neonates. This could have clinical implications...
Preliminary results of fetal cardiac bypass in nonhuman primatesAkio Ikai
Department of Cardiothoracic Surgery, Division of Pediatric Cardiac Surgery, Stanford University School of Medicine, CA, USA
J Thorac Cardiovasc Surg 129:175-81. 2005..Isoflurane anesthesia appears to be superior to fentanyl and midazolam anesthesia for fetal cardiac surgery because of adequate uterine relaxation...
Antegrade cerebral perfusion reduces apoptotic neuronal injury in a neonatal piglet model of cardiopulmonary bypassValerie Y Chock
Department of Neonatology, Stanford University School of Medicine, Stanford, Calif, USA
J Thorac Cardiovasc Surg 131:659-65. 2006..We sought to evaluate and compare the extent of neurologic injury in a neonatal piglet model of deep hypothermic circulatory arrest and antegrade cerebral perfusion...
Mechanical support of total cavopulmonary connection with an axial flow pumpR Kirk Riemer
Department of Cardiothoracic Surgery, Stanford University, CA 94305, USA
J Thorac Cardiovasc Surg 130:351-4. 2005..This is a simple model that can be used to further evaluate the potential of mechanical support as a treatment option in failing Fontan circulation...
Anomalous origin of the pulmonary artery from the aorta: early diagnosis and repair leading to immediate physiological correctionGabriel Amir
Department of Cardiac Surgery, Schneider Children s Medical Center of Israel, Petach Tikva, Israel
Cardiol Young 20:654-9. 2010..The purpose of this study is to present our experience with this rare anomaly, in which early anatomic repair lead to rapid physiologic correction...
The metabolic effects of fresh versus old stored blood in the priming of cardiopulmonary bypass solution for pediatric patientsIlan Keidan
Department of Anesthesia and Intensive Care, Sheba Medical Center, Tel Aviv University, Israel
J Thorac Cardiovasc Surg 127:949-52. 2004..The purpose of the present study was to evaluate the metabolic effects of fresh (< or =5 days) versus old (>5 days) stored packed red blood cells added to the priming solutions of pediatric patients undergoing cardiac surgery...
Unintended right-to-left shunt after Fontan operation: consequence of unligated vertical vein in a child with total anomalous pulmonary venous drainage, single ventricle, and heterotaxyDavid Mishaly
Department of Pediatric Cardiology and Cardiac Surgery, The Chaim Sheba Medical Center, Tel Hashomer, Israel
J Thorac Cardiovasc Surg 125:421-3. 2003
Preservation of myocyte structure and mitochondrial integrity in subzero cryopreservation of mammalian hearts for transplantation using antifreeze proteins--an electron microscopy studyGabriel Amir
Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
Eur J Cardiothorac Surg 24:292-6; discussion 296-7. 2003..Past efforts to cryopreserve mammalian hearts using these proteins were unsuccessful. We report the first successful subzero cryopreservation of rat hearts using fish derived antifreeze proteins with preservation of myocyte structure...
