Andre Altmann

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. doi request reprint Detecting rare variants for psychiatric disorders using next generation sequencing: a methods primer
    Andre Altmann
    Department of Neurology and Neurological Sciences, Functional Imaging in Neurodegenerative Disorders Laboratory, Stanford University, Stanford, CA, USA
    Curr Psychiatry Rep 15:333. 2013
  2. doi request reprint A beginners guide to SNP calling from high-throughput DNA-sequencing data
    Andre Altmann
    Statistical Genetics, Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804 Munich, Germany
    Hum Genet 131:1541-54. 2012
  3. pmc Functional coding variants in SLC6A15, a possible risk gene for major depression
    Carina Quast
    Max Planck Institute of Psychiatry, Munich, Germany
    PLoS ONE 8:e68645. 2013
  4. doi request reprint Rare variants in TMEM132D in a case-control sample for panic disorder
    Carina Quast
    Max Planck Institute of Psychiatry, Munich, Germany
    Am J Med Genet B Neuropsychiatr Genet 159:896-907. 2012
  5. pmc vipR: variant identification in pooled DNA using R
    Andre Altmann
    Department of Statistical Genetics, Max Planck Institute of Psychiatry, Munich, Germany
    Bioinformatics 27:i77-84. 2011
  6. doi request reprint A polymorphism in the Crhr1 gene determines stress vulnerability in male mice
    Christiana Labermaier
    Max Planck Institute of Psychiatry C L, C K, J H, C D, A A, P W, J A, C Q, K V W, S H S, L C, R W A, J B, R L, F H, M U, F H, E B B, M V S, 80804 Munich, Germany Lundbeck Research USA K A J, Paramus, New Jersey 07652 and Johannes Gutenberg University Medical Center M B M, 55131 Mainz, Germany
    Endocrinology 155:2500-10. 2014
  7. pmc Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder
    Divya Mehta
    Max Planck Institute of Psychiatry, 80804 Munich, Germany
    Proc Natl Acad Sci U S A 110:8302-7. 2013
  8. pmc Sex modifies the APOE-related risk of developing Alzheimer disease
    Andre Altmann
    Stanford Center for Memory Disorders, Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA
    Ann Neurol 75:563-73. 2014

Collaborators

Detail Information

Publications8

  1. doi request reprint Detecting rare variants for psychiatric disorders using next generation sequencing: a methods primer
    Andre Altmann
    Department of Neurology and Neurological Sciences, Functional Imaging in Neurodegenerative Disorders Laboratory, Stanford University, Stanford, CA, USA
    Curr Psychiatry Rep 15:333. 2013
    ..Thereby, it aims to introduce the emerging field of MPS into neuropsychiatric research and might serve as a guide for further studies...
  2. doi request reprint A beginners guide to SNP calling from high-throughput DNA-sequencing data
    Andre Altmann
    Statistical Genetics, Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804 Munich, Germany
    Hum Genet 131:1541-54. 2012
    ..To this end, we employ several alignment programs and SNP calling routines for highlighting the fact that the choice of the tools significantly affects the final results...
  3. pmc Functional coding variants in SLC6A15, a possible risk gene for major depression
    Carina Quast
    Max Planck Institute of Psychiatry, Munich, Germany
    PLoS ONE 8:e68645. 2013
    ..As statistically significant association for rare variants might only be achieved in extremely large samples (N >70,000) functional exploration may shed light on putatively disease-relevant variants...
  4. doi request reprint Rare variants in TMEM132D in a case-control sample for panic disorder
    Carina Quast
    Max Planck Institute of Psychiatry, Munich, Germany
    Am J Med Genet B Neuropsychiatr Genet 159:896-907. 2012
    ..Our data suggest that not only common but also putatively functional and/or rare variants within TMEM132D might contribute to the risk to develop anxiety disorders...
  5. pmc vipR: variant identification in pooled DNA using R
    Andre Altmann
    Department of Statistical Genetics, Max Planck Institute of Psychiatry, Munich, Germany
    Bioinformatics 27:i77-84. 2011
    ..The resulting sequence data, however, poses a bioinformatics challenge: the discrimination of sequencing errors from real sequence variants present at a low frequency in the DNA pool...
  6. doi request reprint A polymorphism in the Crhr1 gene determines stress vulnerability in male mice
    Christiana Labermaier
    Max Planck Institute of Psychiatry C L, C K, J H, C D, A A, P W, J A, C Q, K V W, S H S, L C, R W A, J B, R L, F H, M U, F H, E B B, M V S, 80804 Munich, Germany Lundbeck Research USA K A J, Paramus, New Jersey 07652 and Johannes Gutenberg University Medical Center M B M, 55131 Mainz, Germany
    Endocrinology 155:2500-10. 2014
    ..Our results suggest that patients with a specific genetic predisposition in the CRHR1 gene together with an exposure to chronic stress may benefit from a treatment selectively antagonizing CRHR1 hyperactivity. ..
  7. pmc Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder
    Divya Mehta
    Max Planck Institute of Psychiatry, 80804 Munich, Germany
    Proc Natl Acad Sci U S A 110:8302-7. 2013
    ..These results contribute to a better understanding of the extent of influence of differences in trauma exposure on pathophysiological processes in stress-related psychiatric disorders and may have implications for personalized medicine...
  8. pmc Sex modifies the APOE-related risk of developing Alzheimer disease
    Andre Altmann
    Stanford Center for Memory Disorders, Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA
    Ann Neurol 75:563-73. 2014
    ..We examined the APOE4-by-sex interaction in conversion risk (from healthy aging to mild cognitive impairment (MCI)/AD or from MCI to AD) and cerebrospinal fluid (CSF) biomarker levels...