F Abbasi

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. ncbi request reprint Multiple lipoprotein abnormalities associated with insulin resistance in healthy volunteers are identified by the vertical auto profile-II methodology
    James W Chu
    Stanford University School of Medicine, Department of Medicine, Stanford, CA 94305, USA
    Clin Chem 49:1014-7. 2003
  2. ncbi request reprint Body mass index and waist circumference associate to a comparable degree with insulin resistance and related metabolic abnormalities in South Asian women and men
    Fahim Abbasi
    Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    Diab Vasc Dis Res 9:296-300. 2012
  3. doi request reprint Evaluation of fasting plasma insulin concentration as an estimate of insulin action in nondiabetic individuals: comparison with the homeostasis model assessment of insulin resistance (HOMA-IR)
    Fahim Abbasi
    Division of Cardiovascular Medicine, Falk Cardiovascular Research Center, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA, 94305 5406, USA
    Acta Diabetol 51:193-7. 2014
  4. pmc Cardiometabolic risk factors and obesity: does it matter whether BMI or waist circumference is the index of obesity?
    Fahim Abbasi
    Division of Cardiovascular Medicine, Department of Medicine and the Department of Psychiatry, Stanford University School of Medicine, Stanford, CA 94305, USA
    Am J Clin Nutr 98:637-40. 2013
  5. doi request reprint Comparison of two methods using plasma triglyceride concentration as a surrogate estimate of insulin action in nondiabetic subjects: triglycerides × glucose versus triglyceride/high-density lipoprotein cholesterol
    Fahim Abbasi
    Falk Cardiovascular Research Center, Stanford, CA 94305 5406, USA
    Metabolism 60:1673-6. 2011
  6. doi request reprint Relationship between changes in insulin sensitivity and associated cardiovascular disease risk factors in thiazolidinedione-treated, insulin-resistant, nondiabetic individuals: pioglitazone versus rosiglitazone
    Fahim Abbasi
    Division of Cardiovascular Medicine, Falk Cardiovascular Research Center, Stanford University School of Medicine, Stanford, CA 94305, USA
    Metabolism 58:373-8. 2009
  7. doi request reprint Pioglitazone administration decreases cardiovascular disease risk factors in insulin-resistant smokers
    Fahim Abbasi
    Stanford University School of Medicine, CA 94305, USA
    Metabolism 57:1108-14. 2008
  8. pmc Comparison of three treatment approaches to decreasing cardiovascular disease risk in nondiabetic insulin-resistant dyslipidemic subjects
    Fahim Abbasi
    Stanford University School of Medicine, Stanford, CA, USA
    Am J Cardiol 102:64-9. 2008
  9. doi request reprint Pioglitazone decreases postprandial accumulation of remnant lipoproteins in insulin-resistant smokers
    F Abbasi
    Department of Medicine, Cardiovascular Research Center, Stanford University School of Medicine, Stanford, CA 94305 5406, USA
    Diabetes Obes Metab 11:779-85. 2009
  10. doi request reprint What is the effect of rosiglitazone treatment on insulin secretory function in insulin-resistant individuals? It depends on how you measure it
    Fahim Abbasi
    Stanford University School of Medicine, Stanford, CA 94305 5406, USA
    Metabolism 60:57-62. 2011

Collaborators

Detail Information

Publications69

  1. ncbi request reprint Multiple lipoprotein abnormalities associated with insulin resistance in healthy volunteers are identified by the vertical auto profile-II methodology
    James W Chu
    Stanford University School of Medicine, Department of Medicine, Stanford, CA 94305, USA
    Clin Chem 49:1014-7. 2003
  2. ncbi request reprint Body mass index and waist circumference associate to a comparable degree with insulin resistance and related metabolic abnormalities in South Asian women and men
    Fahim Abbasi
    Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    Diab Vasc Dis Res 9:296-300. 2012
    ..The aim of this study was to test the hypothesis that body mass index (BMI) and waist circumference (WC) associate to a comparable degree with insulin resistance and cardiometabolic risk factors in South Asians...
  3. doi request reprint Evaluation of fasting plasma insulin concentration as an estimate of insulin action in nondiabetic individuals: comparison with the homeostasis model assessment of insulin resistance (HOMA-IR)
    Fahim Abbasi
    Division of Cardiovascular Medicine, Falk Cardiovascular Research Center, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA, 94305 5406, USA
    Acta Diabetol 51:193-7. 2014
    ..Calculation of HOMA-IR does not provide a better surrogate estimate of insulin action, or of its associated dyslipidemia, than measurement of FPI. ..
  4. pmc Cardiometabolic risk factors and obesity: does it matter whether BMI or waist circumference is the index of obesity?
    Fahim Abbasi
    Division of Cardiovascular Medicine, Department of Medicine and the Department of Psychiatry, Stanford University School of Medicine, Stanford, CA 94305, USA
    Am J Clin Nutr 98:637-40. 2013
    ..It has been suggested that the cardiometabolic risk associated with excess adiposity is particularly related to central obesity...
  5. doi request reprint Comparison of two methods using plasma triglyceride concentration as a surrogate estimate of insulin action in nondiabetic subjects: triglycerides × glucose versus triglyceride/high-density lipoprotein cholesterol
    Fahim Abbasi
    Falk Cardiovascular Research Center, Stanford, CA 94305 5406, USA
    Metabolism 60:1673-6. 2011
    ..Calculations of TG/HDL-C ratio and TyG index correlated with SSPG concentration to a similar degree, and the relationships were comparable to estimates using fasting insulin. The strongest relationship was between SSPG and insulin-AUC...
  6. doi request reprint Relationship between changes in insulin sensitivity and associated cardiovascular disease risk factors in thiazolidinedione-treated, insulin-resistant, nondiabetic individuals: pioglitazone versus rosiglitazone
    Fahim Abbasi
    Division of Cardiovascular Medicine, Falk Cardiovascular Research Center, Stanford University School of Medicine, Stanford, CA 94305, USA
    Metabolism 58:373-8. 2009
    ..However, despite these similarities, their effects on lipoprotein metabolism seem to be quite different, with beneficial effects confined to PIO-treated individuals...
  7. doi request reprint Pioglitazone administration decreases cardiovascular disease risk factors in insulin-resistant smokers
    Fahim Abbasi
    Stanford University School of Medicine, CA 94305, USA
    Metabolism 57:1108-14. 2008
    ....
  8. pmc Comparison of three treatment approaches to decreasing cardiovascular disease risk in nondiabetic insulin-resistant dyslipidemic subjects
    Fahim Abbasi
    Stanford University School of Medicine, Stanford, CA, USA
    Am J Cardiol 102:64-9. 2008
    ..In conclusion, there did not appear to be 1 therapeutic intervention that effectively treated all metabolic abnormalities present in these patients at greatly increased risk of cardiovascular disease...
  9. doi request reprint Pioglitazone decreases postprandial accumulation of remnant lipoproteins in insulin-resistant smokers
    F Abbasi
    Department of Medicine, Cardiovascular Research Center, Stanford University School of Medicine, Stanford, CA 94305 5406, USA
    Diabetes Obes Metab 11:779-85. 2009
    ..More recently, it has been suggested that an increase in non-fasting triglycerides, rather than fasting hypertriglyceridaemia, is an independent CVD risk factor...
  10. doi request reprint What is the effect of rosiglitazone treatment on insulin secretory function in insulin-resistant individuals? It depends on how you measure it
    Fahim Abbasi
    Stanford University School of Medicine, Stanford, CA 94305 5406, USA
    Metabolism 60:57-62. 2011
    ....
  11. ncbi request reprint Metabolic changes following sibutramine-assisted weight loss in obese individuals: role of plasma free fatty acids in the insulin resistance of obesity
    T McLaughlin
    Department of Medicine, Stanford University, School of Medicine, Stanford, CA, USA
    Metabolism 50:819-24. 2001
    ....
  12. ncbi request reprint Insulin resistance as a predictor of age-related diseases
    F S Facchini
    Department of Medicine, Stanford University, School of Medicine Stanford, California 94305, USA
    J Clin Endocrinol Metab 86:3574-8. 2001
    ....
  13. ncbi request reprint Lipoprotein risk factors for cardiovascular disease in patients with type 2 diabetes mellitus treated with oral antihyperglycaemic agents
    J W Chu
    Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    Diabetes Obes Metab 5:333-7. 2003
    ..To compare lipoprotein risk factors for cardiovascular disease (CVD) in patients with type 2 diabetes mellitus (DM) treated with a sulphonylurea (SU) compound only, metformin (MET) only, or combined SU + MET...
  14. ncbi request reprint Relationship between insulin resistance, weight loss, and coronary heart disease risk in healthy, obese women
    T McLaughlin
    Department of Medicine, Stanford University School of Medicine Stanford, CA, USA
    Metabolism 50:795-800. 2001
    ..Given these data, it seems obvious that attempts to reduce CHD risk factors by weight loss should focus on obese individuals who are also insulin-resistant...
  15. ncbi request reprint Effect of insulin resistance on postprandial elevations of remnant lipoprotein concentrations in postmenopausal women
    H S Kim
    Department of Medicine, Stanford University School of Medicine, California 94305, USA
    Am J Clin Nutr 74:592-5. 2001
    ..001). CONCLUSIONS: Postprandial accumulation of RLPs is accentuated in insulin-resistant, postmenopausal women. This may contribute to the increased risk of CAD in these individuals...
  16. doi request reprint Pioglitazone increases the proportion of small cells in human abdominal subcutaneous adipose tissue
    Tracey M McLaughlin
    Department of Medicine, Stanford University School of Medicine, Stanford, California, USA
    Obesity (Silver Spring) 18:926-31. 2010
    ..These findings support the hypothesis that defects in subcutaneous fat storage may underlie obesity-associated insulin resistance...
  17. ncbi request reprint Insulin resistance, dietary cholesterol, and cholesterol concentration in postmenopausal women
    G M Reaven
    Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA
    Metabolism 50:594-7. 2001
    ....
  18. ncbi request reprint Use of metabolic markers to identify overweight individuals who are insulin resistant
    Tracey McLaughlin
    Stanford University School of Medicine, Stanford, California 94305, USA
    Ann Intern Med 139:802-9. 2003
    ....
  19. ncbi request reprint The relationship between insulin resistance and dyslipidaemia in cigarette smokers
    H M F Farin
    Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA
    Diabetes Obes Metab 9:65-9. 2007
    ..The present study was initiated to determine whether this dyslipidaemia prevalent in cigarette smokers and characteristic of insulin-resistant individuals is a function of cigarette smoking or of insulin resistance...
  20. pmc Adiposity indices in the prediction of metabolic abnormalities associated with cardiovascular disease in non-diabetic adults
    A Liu
    Division of Endocrinology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    Nutr Metab Cardiovasc Dis 21:553-60. 2011
    ....
  21. doi request reprint Persistence of improvement in insulin sensitivity following a dietary weight loss programme
    T McLaughlin
    Department of Medicine, Division of Endocrinology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Diabetes Obes Metab 10:1186-94. 2008
    ..We sought to quantify the degree to which maintenance of weight loss after a short-term dietary intervention was associated with persistent metabolic benefits...
  22. ncbi request reprint Rosiglitazone reduces glucose-stimulated insulin secretion rate and increases insulin clearance in nondiabetic, insulin-resistant individuals
    Sun H Kim
    Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305 5406, USA
    Diabetes 54:2447-52. 2005
    ..In conclusion, enhanced insulin sensitivity in rosiglitazone-treated nondiabetic insulin-resistant individuals was associated with a shift to the right in the GS-ISR dose-response curve and an increase in I-MCR...
  23. ncbi request reprint Effect of rosiglitazone treatment on circulating vascular and inflammatory markers in insulin-resistant subjects
    James W Chu
    Department of Medicine, Stanford University School of Medicine, Stanford, California, 94305, USA
    Diab Vasc Dis Res 2:37-41. 2005
    ....
  24. ncbi request reprint Effect of metformin treatment on multiple cardiovascular disease risk factors in patients with type 2 diabetes mellitus
    Fahim Abbasi
    Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA
    Metabolism 53:159-64. 2004
    ..Administration of metformin, either as monotherapy or in combination with a sulfonylurea drug, improved glycemic control and led to a decrease in several CVD risk factors in patients with type 2 diabetes...
  25. ncbi request reprint The relationship between plasma adiponectin concentration and insulin resistance is altered in smokers
    Fahim Abbasi
    Department of Medicien, Stanford University School of Medicine, CA 94305, USA
    J Clin Endocrinol Metab 91:5002-7. 2006
    ..Low plasma adiponectin concentrations in smokers may contribute to the adverse consequences that occur in these individuals...
  26. ncbi request reprint Differentiation between obesity and insulin resistance in the association with C-reactive protein
    Tracey McLaughlin
    Stanford University School of Medicine, Stanford, Calif, USA
    Circulation 106:2908-12. 2002
    ..Plasma C-reactive protein (CRP) concentrations are increased in obese and/or hyperinsulinemic individuals. The goal of this study was to determine if the relation between insulin resistance and CRP was independent of obesity...
  27. ncbi request reprint Usefulness of plasma glucose and insulin concentrations in identifying patients with insulin resistance
    Cheng Yang Tuan
    Stanford University School of Medicine, Stanford, California 94305, USA
    Am J Cardiol 92:606-10. 2003
    ..We then made standard measurements of plasma glucose and insulin concentrations to see how useful they would be as surrogate markers of insulin resistance...
  28. ncbi request reprint Prevalence of insulin resistance and associated cardiovascular disease risk factors among normal weight, overweight, and obese individuals
    Tracey McLaughlin
    Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA
    Metabolism 53:495-9. 2004
    ..These results show that while BMI and insulin resistance are related, they are not synonymous, and that they make independent and different contributions to increasing CVD risk...
  29. ncbi request reprint Relationship between fasting and day-long plasma glucose concentrations in diet-treated patients with type 2 diabetes
    F Abbasi
    Department of Medicine, Stanford University, School of Medicine Stanford, CA 94305 5406, USA
    Metabolism 51:457-9. 2002
    ....
  30. doi request reprint Plasma glucose and insulin responses to mixed meals: impaired fasting glucose re-visited
    Sl Bhat
    Stanford University School of Medicine, CA 94305 5103, USA
    Diab Vasc Dis Res 8:271-5. 2011
    ....
  31. ncbi request reprint Relation between insulin resistance and plasma concentrations of lipid hydroperoxides, carotenoids, and tocopherols
    F S Facchini
    Department of Medicine, Division of Nephrology, San Francisco General Hospital, CA 94110, USA
    Am J Clin Nutr 72:776-9. 2000
    ..It is not known whether total circulating lipid hydroperoxides are increased in insulin-resistant individuals and whether this correlates with depletion of liposoluble antioxidant vitamins that are consumed during lipid peroxidation...
  32. ncbi request reprint Relationship between obesity, insulin resistance, and coronary heart disease risk
    Fahim Abbasi
    Department of Medicine, Stanford, California, USA
    J Am Coll Cardiol 40:937-43. 2002
    ....
  33. ncbi request reprint Impact of degree of obesity on surrogate estimates of insulin resistance
    Sun H Kim
    Department of Medicine, Stanford University School of Medicine, Stanford, California, USA
    Diabetes Care 27:1998-2002. 2004
    ..To evaluate the role of adiposity in the relationship between specific and surrogate estimates of insulin-mediated glucose uptake (IMGU) in a large nondiabetic population...
  34. ncbi request reprint Obesity, insulin resistance, and cardiovascular disease
    Gerald Reaven
    School of Medicine, Stanford University, Stanford, California 94305, USA
    Recent Prog Horm Res 59:207-23. 2004
    ....
  35. ncbi request reprint Metformin treatment lowers asymmetric dimethylarginine concentrations in patients with type 2 diabetes
    T Asagami
    Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA
    Metabolism 51:843-6. 2002
    ....
  36. ncbi request reprint Plasma adiponectin concentrations do not increase in association with moderate weight loss in insulin-resistant, obese women
    Fahim Abbasi
    Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    Metabolism 53:280-3. 2004
    ..Adiponectin concentrations did not change with weight loss in either group. Thus, neither weight loss, per se, nor enhanced insulin sensitivity resulted in a change in plasma adiponectin concentrations...
  37. ncbi request reprint Body mass index and waist circumference both contribute to differences in insulin-mediated glucose disposal in nondiabetic adults
    Helke M F Farin
    Stanford University School of Medicine, Stanford, CA 94305, USA
    Am J Clin Nutr 83:47-51. 2006
    ..Questions remain as to whether waist circumference (WC) or body mass index (BMI) most effectively identifies insulin-resistant individuals...
  38. ncbi request reprint Plasma asymmetric dimethylarginine concentrations are elevated in obese insulin-resistant women and fall with weight loss
    Tracey McLaughlin
    Division of Endocrinology, Stanford University School of Medicine, Stanford, California 94305 5103, USA
    J Clin Endocrinol Metab 91:1896-900. 2006
    ..Plasma asymmetric dimethylarginine (ADMA) concentrations are higher in apparently healthy, insulin-resistant (IR) individuals and decrease in response to thiazolidenedione treatment...
  39. ncbi request reprint Clinical experience with a relatively low carbohydrate, calorie-restricted diet improves insulin sensitivity and associated metabolic abnormalities in overweight, insulin resistant South Asian Indian women
    Andrea C Backes
    Department of Medicine, Stanford University Medical Center, Stanford, CA, USA
    Asia Pac J Clin Nutr 17:669-71. 2008
    ....
  40. doi request reprint Comparison of waist circumference versus body mass index in diagnosing metabolic syndrome and identifying apparently healthy subjects at increased risk of cardiovascular disease
    Marno Celeste Ryan
    Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA
    Am J Cardiol 102:40-6. 2008
    ..BMI identified individuals at increased cardiovascular disease risk as effectively as determination of WC...
  41. pmc Insulin resistance is associated with a modest increase in inflammation in subcutaneous adipose tissue of moderately obese women
    T McLaughlin
    Department of Medicine, Division of Endocrinology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305 5103, USA
    Diabetologia 51:2303-8. 2008
    ..To determine whether other biological properties also differ between IR and IS obese individuals, we quantified markers of inflammatory activity in adipose tissue from overweight IR and IS individuals...
  42. ncbi request reprint Improvement in insulin sensitivity followed by ovulation and pregnancy in a woman with polycystic ovary syndrome who was treated with rosiglitazone
    N A Cataldo
    Division of Reproductive Endocrinology and Infertility, Department of Gynecology and Obstetrics, Stanford University Medical Center, California 94305 5317, USA
    Fertil Steril 76:1057-9. 2001
    ..To determine the metabolic and reproductive effectiveness of rosiglitazone in polycystic ovary syndrome (PCOS)...
  43. pmc Relationship between body mass index and insulin resistance in patients treated with second generation antipsychotic agents
    Sun H Kim
    Department of Medicine, 300 Pasteur Drive, S025, Stanford, CA 94305 5103, USA
    J Psychiatr Res 44:493-8. 2010
    ..Olanzapine also appears to have an independent effect on insulin resistance that is above and beyond obesity...
  44. doi request reprint Glucose-stimulated insulin secretion in gastric bypass patients with hypoglycemic syndrome: no evidence for inappropriate pancreatic beta-cell function
    Sun H Kim
    Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA
    Obes Surg 20:1110-6. 2010
    ..The syndrome is believed to occur due to insulin hypersecretion from either pancreatic beta-cell hyperplasia or hyperfunction...
  45. doi request reprint Plasma glucose and insulin regulation is abnormal following gastric bypass surgery with or without neuroglycopenia
    Sun H Kim
    Department of Medicine, Stanford University Medical Center, 300 Pasteur Drive, Room S025, Stanford, CA 94305 5103, USA
    Obes Surg 19:1550-6. 2009
    ....
  46. pmc Differential intra-abdominal adipose tissue profiling in obese, insulin-resistant women
    Alice Liu
    Division of Endocrinology, Department of Medicine, Stanford University Medical Center, 300 Pasteur Drive Rm S 025, Stanford, CA 94305, USA
    Obes Surg 19:1564-73. 2009
    ..We compared cell size distribution and genetic markers in SAT and VAT of IR individuals undergoing bariatric surgery...
  47. ncbi request reprint Relationship between insulin resistance and an endogenous nitric oxide synthase inhibitor
    Markus C Stühlinger
    Division of Cardiovascular Medicine, Stanford University School of Medicine, Falk Cardiovascular Research Center, 300 Pasteur Dr, Stanford, CA 94305, USA
    JAMA 287:1420-6. 2002
    ..Several cardiovascular risk factors are associated with reduced sensitivity to insulin, but elevated ADMA concentrations have not been fully linked to the metabolic syndrome...
  48. pmc Effect of moderate alcoholic beverage consumption on insulin sensitivity in insulin-resistant, nondiabetic individuals
    Sun H Kim
    Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305 5103, USA
    Metabolism 58:387-92. 2009
    ....
  49. ncbi request reprint Lipoprotein abnormalities are associated with insulin resistance in South Asian Indian women
    Latha P Palaniappan
    Stanford Prevention Research Center and Division of Cardiovascular Medicine Department of Medicine, Stanford University Medical Center, Stanford, CA 94305, USA
    Metabolism 56:899-904. 2007
    ..These results indicate that a highly atherogenic lipoprotein profile seen in South Asian Indian women is significantly associated with insulin resistance independent of differences in WC...
  50. ncbi request reprint Body mass index and waist circumference correlate to the same degree with insulin-mediated glucose uptake
    Helke M F Farin
    Cardiovascular Medicine Division Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    Metabolism 54:1323-8. 2005
    ..To summarize, (1) BMI and WC correlate closely within an individual and equally well with IMGU, and (2) BMI is as effective as WC in identifying insulin-resistant individuals...
  51. ncbi request reprint Metabolic and ovarian effects of rosiglitazone treatment for 12 weeks in insulin-resistant women with polycystic ovary syndrome
    Nicholas A Cataldo
    Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    Hum Reprod 21:109-20. 2006
    ..Insulin sensitizers have favourable metabolic and ovarian effects in polycystic ovary syndrome (PCOS). This study examined rosiglitazone, a thiazolidinedione, in PCOS...
  52. ncbi request reprint Relative effects of insulin resistance and protease inhibitor treatment on lipid and lipoprotein metabolism in HIV-infected patients
    George Beatty
    Department of Medicine, University of California San Francisco at San Francisco General Hospital, San Francisco, California 94110, USA
    HIV Clin Trials 5:383-91. 2004
    ..The relationship between insulin resistance, dyslipidemia, HIV infection, and antiretroviral therapy remains unclear, and the atherogenic nature of lipid and lipoprotein profiles in HIV-infected patients has not been fully characterized...
  53. ncbi request reprint Effects of moderate variations in macronutrient composition on weight loss and reduction in cardiovascular disease risk in obese, insulin-resistant adults
    Tracey McLaughlin
    Stanford University School of Medicine, Stanford, CA 94305, USA
    Am J Clin Nutr 84:813-21. 2006
    ..Obese, insulin-resistant persons are at risk of cardiovascular disease. How best to achieve both weight loss and clinical benefit in these persons is controversial, and recent reports questioned the superiority of low-fat diets...
  54. ncbi request reprint Comparative effects of rosuvastatin and gemfibrozil on glucose, insulin, and lipid metabolism in insulin-resistant, nondiabetic patients with combined dyslipidemia
    Cindy Lamendola
    Department of Medicine, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
    Am J Cardiol 95:189-93. 2005
    ..05) in rosuvastatin-treated patients, and this difference in the relative effectiveness of the drugs was also true of the decrease in non-high-density lipoprotein cholesterol concentrations...
  55. ncbi request reprint Methods for quantifying insulin resistance in human immunodeficiency virus-positive patients
    James W Chu
    Department of Medicine, Stanford University School of Medicine, CA, USA
    Metabolism 52:858-61. 2003
    ..43 to 0.61), thereby possessing limited ability to predict SSPG variability (r2=0.18 to 0.37). In conclusion, indirect measures of IMGU need to be applied with caution when evaluating insulin action in HIV-infected patients...
  56. ncbi request reprint Serum alanine aminotransferase levels decrease further with carbohydrate than fat restriction in insulin-resistant adults
    Marno Celeste Ryan
    Division of Cardiovascular Medicine, Falk Cardiovascular Research Center, 300 Pasteur Dr, Stanford University, Stanford, CA 94305 5406, USA
    Diabetes Care 30:1075-80. 2007
    ..We assessed the effect on serum alanine aminotransferase (ALT) concentrations of two hypocaloric diets varying in amounts of carbohydrate and fat in obese insulin-resistant individuals, a population at high risk for NAFLD...
  57. ncbi request reprint Heterogeneity in the prevalence of risk factors for cardiovascular disease and type 2 diabetes mellitus in obese individuals: effect of differences in insulin sensitivity
    Tracey McLaughlin
    Division of Endocrinology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
    Arch Intern Med 167:642-8. 2007
    ..We tested the hypothesis that risk factors for type 2 diabetes mellitus and cardiovascular disease vary dramatically in moderately obese individuals as a function of differences in a specific measure of insulin sensitivity...
  58. ncbi request reprint Clinical efficacy of two hypocaloric diets that vary in overweight patients with type 2 diabetes: comparison of moderate fat versus carbohydrate reductions
    Tracey McLaughlin
    Department of Endocrinology, Stanford University, 300 Pasteur Dr, Stanford, CA 94305 5103, USA
    Diabetes Care 30:1877-9. 2007
  59. ncbi request reprint Is there a simple way to identify insulin-resistant individuals at increased risk of cardiovascular disease?
    Tracey McLaughlin
    Stanford University School of Medicine, Stanford, California, USA
    Am J Cardiol 96:399-404. 2005
    ..5 provides a simple means of identifying insulin-resistant, dyslipidemic patients who are likely to be at increased risk of cardiovascular disease...
  60. ncbi request reprint Evaluation of the quantitative insulin sensitivity check index as an estimate of insulin sensitivity in humans
    F Abbasi
    Department of Medicine, Stanford University, School of Medicine Stanford, CA 94305, USA
    Metabolism 51:235-7. 2002
    ..Furthermore, none of the 3 surrogate estimates can account for more than approximately 40% of the variability of the difference in insulin-mediated glucose disposal measured directly in 490 healthy, nondiabetic volunteers...
  61. ncbi request reprint Comparison in patients with type 2 diabetes of fibric acid versus hepatic hydroxymethyl glutaryl-coenzyme a reductase inhibitor treatment of combined dyslipidemia
    Tracey McLaughlin
    Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA
    Metabolism 51:1355-9. 2002
    ..As such, the clinical utility of statin monotherapy in the treatment of combined dyslipidemia may have been underestimated...
  62. doi request reprint Comparison of surrogate and direct measurement of insulin resistance in chronic hepatitis C virus infection: impact of obesity and ethnicity
    Khoa D Lam
    Department of Medicine, University of California San Francisco, San Francisco, CA, USA
    Hepatology 52:38-46. 2010
    ..Repeat HOMA-IR measurements had higher within-person variation in the obese (standard deviation = 0.77 higher than normal-weight, 95% confidence interval = 0.25-1.30, P = 0.005)...
  63. ncbi request reprint Discrimination between obesity and insulin resistance in the relationship with adiponectin
    Fahim Abbasi
    Divisions of Cardiovascular Medicine and Endocrinology and Metabolism, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA
    Diabetes 53:585-90. 2004
    ..These results suggest that adiponectin concentrations are more closely related to differences in insulin-mediated glucose disposal than obesity...
  64. ncbi request reprint Quantification of insulin-mediated glucose disposal in HIV-infected individuals: comparison of patients treated and untreated with protease inhibitors
    George Beatty
    Department of Medicine, University of California San Francisco, San Francisco General Hospital, San Francisco, California 94110, USA
    J Acquir Immune Defic Syndr 33:34-40. 2003
    ..Finally, PI treatment may have an inhibitory effect on insulin secretion...
  65. ncbi request reprint Comparison of body mass index versus waist circumference with the metabolic changes that increase the risk of cardiovascular disease in insulin-resistant individuals
    Helke M F Farin
    Stanford University School of Medicine, Stanford, California, USA
    Am J Cardiol 98:1053-6. 2006
    ..In conclusion, because BMI performed at least as well as WC in identifying differences in insulin sensitivity and multiple CVD risk factors, either estimate can be used to identify patients at increased CVD risk...
  66. ncbi request reprint Improvements in insulin resistance with weight loss, in contrast to rosiglitazone, are not associated with changes in plasma adiponectin or adiponectin multimeric complexes
    Fahim Abbasi
    Division of Endocrinology and Metabolism, Deptartment of Medicine, Carl T Hayden Veterans Affairs Medical Center, 650 East Indian School Road, Phoenix, AZ 85012, USA
    Am J Physiol Regul Integr Comp Physiol 290:R139-44. 2006
    ....
  67. ncbi request reprint Relationship to insulin resistance of the adult treatment panel III diagnostic criteria for identification of the metabolic syndrome
    Karen L Cheal
    Department of Psychiatry, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Diabetes 53:1195-200. 2004
    ..The individual components vary both in terms of their utility in making a diagnosis of the metabolic syndrome and their relationship to insulin resistance, with the obesity and lipid criteria being most useful...
  68. ncbi request reprint Plasma ghrelin concentrations are decreased in insulin-resistant obese adults relative to equally obese insulin-sensitive controls
    Tracey McLaughlin
    Division of Endocrinology, University of Washington, Veterans Affairs Puget Sound Health Care System, Seattle, Washington 98108, USA
    J Clin Endocrinol Metab 89:1630-5. 2004
    ..Thus, insulin resistance or related metabolic abnormalities may constitute part of a feedback mechanism by which body weight is regulated in humans...
  69. ncbi request reprint Prevalence of insulin resistance and the metabolic syndrome with alternative definitions of impaired fasting glucose
    Earl S Ford
    Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Atherosclerosis 181:143-8. 2005
    ..The clinical and public health implications of the new IFG definition remain to be elucidated...