Genomes and Genes
Organization: Stanford University
- Acquisition of MRI equipment by doctors drives up imaging use and spendingLaurence C Baker
Stanford University, California, USA
Health Aff (Millwood) 29:2252-9. 2010..Not only did MRI spending increase for their patients, but spending for other aspects of care rose as well. Attention should be paid to ensuring that advanced medical equipment acquired in physician practices is used appropriately...
- Cervical corpectomy: complications and outcomesMaxwell Boakye
Outcomes Research Lab, Palo Alto Veterans Health Care System, and Department of Neurosurgery, Stanford University School of Medicine, Stanford, California 94304, USA
Neurosurgery 63:295-301; discussion 301-2. 2008..The aim of this study was to report 30-day mortality and complication rates after cervical corpectomy using multicenter prospective data from the Veterans Affairs National Surgical Quality Improvement Program database...
- Outcomes of reparative and transplantation strategies for multilevel left heart obstructions with mitral stenosisSunil P Malhotra
The Children s Hospital Heart Institute, Children s Hospital, Denver, Colorado, USA
Ann Thorac Surg 86:1305-9; discussion 1310. 2008..This study reviews our experience with reconstructive and transplantation approaches for Shone's complex...
- SIR 2008 annual meeting film panel case: Arterial endofibrosisDaniel Y Sze
Division of Interventional Radiology, Stanford University Medical Center, H-3646, 300 Pasteur Drive, Stanford, CA 94305-5642, USA
J Vasc Interv Radiol 19:1271-3. 2008
- Women's childhood and adult adverse experiences, mental health, and binge drinking: the California Women's Health SurveyChristine Timko
Center for Health Care Evaluation, Department of Veterans Affairs VA Health Care System, 795 Willow Road, Menlo Park, CA 94025, USA
Subst Abuse Treat Prev Policy 3:15. 2008..This study examined sociodemographic, physical and mental health, and adult and childhood adverse experiences associated with binge drinking in a representative sample of women in the State of California...
- Meditation with yoga, group therapy with hypnosis, and psychoeducation for long-term depressed mood: a randomized pilot trialLisa D Butler
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305 571, USA
J Clin Psychol 64:806-20. 2008..Although all groups reported some reduction in symptom levels, they did not differ significantly in that outcome. Overall, these results suggest that these two interventions show promise for treating low- to moderate-level depression...
- Internationalizing the Broselow tape: how reliable is weight estimation in Indian childrenNaresh Ramarajan
Stanford University School of Medicine, Stanford, CA, USA
Acad Emerg Med 15:431-6. 2008..The study objective was to determine the accuracy of the Broselow tape in the Indian pediatric population...
- Suspended-drop electroporation for high-throughput delivery of biomolecules into cellsEmmanuel G Guignet
Department of Chemical and Systems Biology, Bio X Program, Clark Center, 318 Campus Drive, Stanford University School of Medicine, Stanford, California 94305, USA
Nat Methods 5:393-5. 2008....
- Transcription factor Lim1 specifies horizontal cell laminar position in the retinaMilica A Margeta
Neurosciences Program, Stanford University, Stanford, California 94305-5020, USA
J Neurosci 28:3835-6. 2008
- Who is at risk for dropout from group cognitive-behavior therapy for insomnia?Jason C Ong
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA
J Psychosom Res 64:419-25. 2008....
- Phenotypic changes in influenza-specific CD8+ T cells after immunization of children and adults with influenza vaccinesXiao Song He
Departments of Medicine, Stanford University School of Medicine, Stanford
J Infect Dis 197:803-11. 2008..These differences are potentially affected by the different routes of vaccination and pathways of antigen presentation for TIV and LAIV...
- The use of dexmedetomidine during laryngoscopy, bronchoscopy, and tracheal extubation following tracheal reconstructionJeannie L Seybold
Division of Pediatric Anesthesia, Department of Anesthesia, Stanford University School of Medicine, Stanford, CA 94305 5640, USA
Paediatr Anaesth 17:1212-4. 2007..Dexmedetomidine in combination with propofol provided appropriately deep anesthesia during these brief but stimulating procedures without cardiovascular or respiratory depression...
- Repeated aerosolized AAV-CFTR for treatment of cystic fibrosis: a randomized placebo-controlled phase 2B trialRichard B Moss
Department of Pediatrics, Stanford University, Stanford, CA 94305, and Division of Respiratory Diseases, Children s Hospital Boston, MA 02115, USA
Hum Gene Ther 18:726-32. 2007..Because gene transfer is the simplest, most basic way to correct the underlying genetic defect that leads to disease in CF, further research is warranted to develop an effective gene transfer agent for the treatment of CF...
- Effects of fast food branding on young children's taste preferencesThomas N Robinson
Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305 5705, USA
Arch Pediatr Adolesc Med 161:792-7. 2007..To examine the effects of cumulative, real-world marketing and brand exposures on young children by testing the influence of branding from a heavily marketed source on taste preferences...
- Use of simulation based team training for obstetric crises in resident educationKay Daniels
Department of Obstetrics and Gynecology, Stanford University, Stanford, CA, USA
Simul Healthc 3:154-60. 2008..This educational paradigm has inherent limitations. During actual crises insufficient time exists for discussion and analysis of patient care. Our objective was to create a simulation program to fill this experiential gap...
- Fentanyl transdermal analgesia during pregnancy and lactationRonald S Cohen
Stanford University, School of Medicine, Lucile S Packard Children s Hospital, Palo Alto, CA 94304, USA
J Hum Lact 25:359-61. 2009..4 ng/ mL. The infant's blood fentanyl level was undetectable. This preliminary report suggests that fentanyl transdermal patch treatment might be a viable option for managing chronic pain during lactation...
- Epidural ropivacaine concentrations for intraoperative analgesia during major upper abdominal surgery: a prospective, randomized, double-blinded, placebo-controlled studyPeriklis Panousis
Department of Anesthesiology and Intensive Care Medicine, University Hospital Carl Gustav Carus, Fetscherstr 74, 01307 Dresden, Germany
Anesth Analg 108:1971-6. 2009..We performed this study among patients undergoing major upper abdominal surgery under combined TEA and general anesthesia...
- How the Golgi works: a cisternal progenitor modelSuzanne R Pfeffer
Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305 5307, USA
Proc Natl Acad Sci U S A 107:19614-8. 2010....
- Changes in in vivo knee loading with a variable-stiffness intervention shoe correlate with changes in the knee adduction momentJennifer C Erhart
Department of Mechanical Engineering, Stanford University, Stanford, California, USA
J Orthop Res 28:1548-53. 2010..The reductions in the external knee adduction moment are indicative of reductions in in vivo medial compressive force with this intervention...
- Hippocampal CA1 apical neuropil atrophy in mild Alzheimer disease visualized with 7-T MRIG A Kerchner
Stanford Center for Memory Disorders, Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305 5235, USA
Neurology 75:1381-7. 2010..In this cross-sectional study, we tested whether tissue loss in the CA1 apical neuropil layer can be observed in vivo in patients with mild AD...
- MicroTrack: an algorithm for concurrent projectome and microstructure estimationAnthony J Sherbondy
Psychology Department, Stanford University, USA
Med Image Comput Comput Assist Interv 13:183-90. 2010..In particular, a simple experiment demonstrates the resolution of the well known ambiguity between crossing and kissing fibers. The results strongly motivate further development of this kind of algorithm for brain connectivity mapping...
- Saliency, switching, attention and control: a network model of insula functionVinod Menon
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 780 Welch Road, Stanford, CA 94304, USA
Brain Struct Funct 214:655-67. 2010..We suggest that this framework provides a parsimonious account of insula function in neurotypical adults, and may provide novel insights into the neural basis of disorders of affective and social cognition...
- Reproductive status regulates expression of sex steroid and GnRH receptors in the olfactory bulbKaren P Maruska
Biology Department, Stanford University, 371 Serra Mall, Stanford, CA 94305, USA
Behav Brain Res 213:208-17. 2010....
- Three-dimensional kinematics of the upper limb during a Reach and Grasp Cycle for childrenErin E Butler
Department of Bioengineering, Stanford University, United States
Gait Posture 32:72-7. 2010....
- Treatment of persistent patent ductus arteriosus in preterm infants: time to accept the null hypothesis?W E Benitz
Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, CA 94304 1510, USA
J Perinatol 30:241-52. 2010..A definitive trial, comparing current standard management with novel strategies not primarily intended to achieve ductal closure, may be necessary to resolve doubts regarding the quality or conduct of prior studies...
- Reconstruction and EMG-informed control, simulation and analysis of human movement for athletics: performance improvement and injury preventionEmel Demircan
Mechanical Engineering Department, Stanford University, Stanford, CA 94305, USA
Conf Proc IEEE Eng Med Biol Soc 2009:6534-7. 2009..We also present a dynamic control and analysis framework that integrates these metrics for the purpose of reconstructing and analyzing sports motions in real-time...
- Insomnia and depression: a multifaceted interplayRachel Manber
Department of Psychiatry and Behavioral Sciences, Stanford University, 401 Quarry Road, Stanford, CA 94305, USA
Curr Psychiatry Rep 11:437-42. 2009....
- Health disparities and children in immigrant families: a research agendaFernando S Mendoza
Department of Pediatrics, School of Medicine, Stanford University, Lucile Packard Children s Hospital, 770 Welch Rd, Suite 100, Palo Alto, CA 94304, USA
Pediatrics 124:S187-95. 2009....
- Basic principles of electrolyte chemistry for microfluidic electrokinetics. Part II: Coupling between ion mobility, electrolysis, and acid-base equilibriaAlexandre Persat
Department of Mechanical Engineering, Stanford University, Stanford, CA 94305, USA
Lab Chip 9:2454-69. 2009..As a whole, the discussions highlight the importance of the coupling between electromigration and electrophoresis, acid-base equilibria, and electrochemical reactions...
- In vivo measurement of ethanol metabolism in the rat liver using magnetic resonance spectroscopy of hyperpolarized [1-13C]pyruvateDaniel M Spielman
Stanford University Department of Radiology, Lucas Center for Medical Imaging, Stanford, CA 94305, USA
Magn Reson Med 62:307-13. 2009....
- Minimal access portoenterostomy: advantages and disadvantages of standard laparoscopic and robotic techniquesSanjeev Dutta
Division of Pediatric Surgery, Lucile Packard Children s Hospital, Stanford University Medical Center, Stanford, CA 94305, USA
J Laparoendosc Adv Surg Tech A 17:258-64. 2007..We reviewed our experience with minimal access portoenterostomy to compare the relative advantages and disadvantages of standard laparoscopic and robotic approaches to biliary atresia...
- Complication rates on weekends and weekdays in US hospitalsEran Bendavid
Center for Health Policy, Stanford Medical School, Stanford, Calif 94305, USA
Am J Med 120:422-8. 2007..Recent studies and anecdotal evidence suggest that patient safety may be compromised on weekends. Our objective was to determine whether rates of complications in hospitals are higher on weekends than on weekdays...
- Potential relationship between gastroesophageal reflux disease and atrial arrhythmiasLauren B Gerson
Division of Gastroenterology, Stanford University School of Medicine, Stanford, CA 94605 5202, USA
J Clin Gastroenterol 40:828-32. 2006....
- Why spurning food biotech has become a liabilityHenry I Miller
Hoover Institution, Stanford University, Stanford, California 94305-6010, USA
Nat Biotechnol 24:1075-7. 2006
- Diffusion tensor imaging and agingEdith V Sullivan
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 401 Quarry Road, Stanford, CA 94305, USA
Neurosci Biobehav Rev 30:749-61. 2006..These hypotheses are not mutually exclusive but establish a basis for posing testable questions about brain systems recruited when those used in youth are altered by aging...
- Concern for the in-group and opposition to affirmative actionBrian S Lowery
Graduate School of Business, Stanford University, CA 94305, USA
J Pers Soc Psychol 90:961-74. 2006..In Experiments 2 and 3, perceived fairness mediated these effects...
- Wood density and vessel traits as distinct correlates of ecological strategy in 51 California coast range angiospermsKatherine A Preston
Department of Biological Sciences, Stanford University, Stanford, CA 94305 5020, USA
New Phytol 170:807-18. 2006..Within a narrow range of wood density, there was significant variation in vessel traits. Given their particular ecological associations, the results suggest that wood density and vessel traits describe two distinct ecological axes...
- Palladium-catalyzed asymmetric ring expansion of allenylcyclobutanols: an asymmetric Wagner-Meerwein shiftBarry M Trost
Department of Chemistry, Stanford University, Stanford, California 94305 5080, USA
J Am Chem Soc 128:6044-5. 2006..In addition, we obtained excellent diastereoselectivity and enantioselectivity at the same time by using 3-monosubstituted allenylcyclobutanol...
- Cutaneous squamous cell carcinoma: a comprehensive clinicopathologic classification--part twoDavid S Cassarino
Department of Pathology, Stanford University, Palo Alto, CA 94305, USA
J Cutan Pathol 33:261-79. 2006....
- Correlates of sleep-onset REM periods during the Multiple Sleep Latency Test in community adultsEmmanuel Mignot
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Palo Alto, CA, USA
Brain 129:1609-23. 2006..These results suggest a high prevalence of narcolepsy without cataplexy, as defined by the International Classification of Sleep Disorders, and/or a large number of false-positives for the MSLT...
- Ethnicity, stress, and cortisol function in Hispanic and non-Hispanic white women: A preliminary study of family dementia caregivers and noncaregiversDolores Gallagher-Thompson
Department of Psychiatry, Stanford University School of Medicine, USA
Am J Geriatr Psychiatry 14:334-42. 2006..Dependent variables were perceived stress, depression, and salivary cortisol...
- Anesthesia for older patients with hypertrophic cardiomyopathy: Is there cause for concern?Timothy Angelotti
Department of Anesthesia, Stanford University School of Medicine, Stanford, CA 94305, USA
J Clin Anesth 17:478-81. 2005..In addition, recent findings concerning the natural progression of HCM are discussed, revealing differences between HCM in younger patient populations and that in older patient populations and its implications for anesthetic management...
- Cramér-Rao bounds for three-point decomposition of water and fatAngel R Pineda
Department of Radiology, Stanford University Medical Center, Stanford, California 94305, USA
Magn Reson Med 54:625-35. 2005..These theoretical results were verified using Monte Carlo simulations with a newly developed nonlinear least-squares reconstruction algorithm that achieves the CRB...
- Molecular virology of the hepatitis C virus: implication for novel therapiesJeffrey S Glenn
Division of Gastroenterology and Hepatology, Stanford University School of Medicine and Palo Alto Veterans Administration Medical Center, CCSR Building, Room 3115, 269 Campus Drive, Palo Alto, CA 94305 5187, USA
Clin Liver Dis 9:353-69, v. 2005..This should minimize the emergence of resistance against any single agent. The way we treat HCV should change dramatically over the next few years...
- Rapid gridding reconstruction with a minimal oversampling ratioPhilip J Beatty
Magnetic Resonance Systems Research Laboratory, Department of Electrical Engineering, Stanford University, Packard 210, 350 Serra Mall, Stanford, CA 94305, USA
IEEE Trans Med Imaging 24:799-808. 2005....
- Indirect effects of large herbivores on snakes in an African savannaDouglas J McCauley
Department of Biological Sciences, Stanford University, Stanford, California 94305, USA
Ecology 87:2657-63. 2006..This is the first empirical demonstration of the indirect effects of large herbivores on snake abundance and presents an interesting example of how the influence of dominant and keystone species can move through a food web...
- Dual-axes confocal reflectance microscope for distinguishing colonic neoplasiaJonathan T C Liu
Ginzton Laboratory, Stanford University, Stanford, California 94305, USA
J Biomed Opt 11:054019. 2006..This design is scalable to millimeter dimensions, and the results demonstrate the potential for a miniature instrument to detect precancerous tissues, and hence to perform in vivo histopathology...
- Identifying novel proteins recognizing histone modifications using peptide pull-down assayJoanna Wysocka
Department of Molecular Pharmacology and Developmental Biology, Stanford University, 269 Campus Drive, Stanford, CA 94305, USA
Methods 40:339-43. 2006..I provide detailed protocols and suggestions for troubleshooting...
- Epidemiology and aetiology of marathon running injuriesMichael Fredericson
Department of Orthopaedic Surgery, Division of Physical Medicine and Rehabilitation, Stanford University School of Medicine and Team Physician, Stanford University Cross Country and Track Teams, Stanford, California 94305 5336, USA
Sports Med 37:437-9. 2007..g. patellofemoral syndrome). Iliotibial band friction syndrome, tibial stress syndrome, plantar fasciitis, Achilles tendonitis and meniscal injuries of the knee were also commonly cited...
- Tumour microenvironment: laminin 332 in squamous-cell carcinomaM Peter Marinkovich
VA Medical Center, Palo Alto, California, USA
Nat Rev Cancer 7:370-80. 2007..The extracellular interactions of laminin 332 appear amenable to antibody-mediated therapies...
- Heritability of left ventricular mass in Japanese families living in Hawaii: the SAPPHIRe StudyThemistocles L Assimes
Stanford University Medical Center, Division of Cardiovascular Medicine, Stanford, California, USA
J Hypertens 25:985-92. 2007..An estimate of this proportion has not been reported previously in an East Asian population. The objective of this study was to estimate the heritability of LV mass in Japanese families living in Hawaii...
- An unusual cause of incessant tachycardiaPirooz S Mofrad
Cardiac Electrophysiology and Arrhythmia Service, Stanford University Medical Center, Stanford, California 94305-5233, USA
Pacing Clin Electrophysiol 30:418-20. 2007
- Uterine epithelioid trophoblastic tumor in an African green monkey (Chlorocebus aethiops sabaeus)David Chu
Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California at Los Angeles, and Department of Veteran s Affairs, The Greater Los Angeles Healthcare System, USA
J Am Assoc Lab Anim Sci 46:92-6. 2007..Overall, the histologic and immunohistochemical features of this tumor were consistent with those of epithelioid trophoblastic tumor. This rare tumor type has not been reported previously to occur in African green monkeys...
- Good feelings in christianity and buddhism: religious differences in ideal affectJeanne L Tsai
Stanford University, Stanford, CA 94305, USA
Pers Soc Psychol Bull 33:409-21. 2007..g., Gospels, Lotus Sutra) and contemporary self-help books (e.g., Your Best Life Now, Art of Happiness). Findings supported predictions, suggesting that AVT applies to religious and to national and ethnic cultures...
- Deltoid flap combined with fascia lata autograft for rotator cuff defects: a histologic studyTimothy R McAdams
Division of Sports Medicine, Department of Orthopaedic Surgery, Stanford University Medical Center, 1000 Welch Road, Suite 100, Palo Alto, CA, 94304, USA
Knee Surg Sports Traumatol Arthrosc 15:1144-9. 2007..A mutually beneficial relationship may exist when an autogenous fascial graft is combined with a functional deltoid flap for reconstructing large rotator cuff defects...
- Childhood risk factors for thin body preoccupation and social pressure to be thinW Stewart Agras
Department of Psychiatry, Stanford University School of Medicine, Stanford, CA 94305, USA
J Am Acad Child Adolesc Psychiatry 46:171-8. 2007..Thin body preoccupation and social pressure to be thin (TBPSP) in adolescence are risk factors for the development of full and partial bulimia nervosa and binge eating disorder. This study examined precursors of these potent risk factors...
- Laparoscopic renal surgery for benign diseaseJoseph C Liao
Department of Urology, Stanford University School of Medicine and VA Palo Alto Health Care System, 3801 Miranda Avenue, MC112, Palo Alto, CA 94304, USA
Curr Urol Rep 8:12-8. 2007..We discuss the technical aspects of both transperitoneal and retroperitoneal approaches. Finally, laparoscopic cyst decortication and some of the novel applications of laparoscopic renal surgery are highlighted...
- The pancreatic stellate cell: a star on the rise in pancreatic diseasesM Bishr Omary
Department of Medicine, VA Palo Alto Health Care System, Palo Alto, California 94304, USA
J Clin Invest 117:50-9. 2007..Therefore, understanding the biology of PaSCs offers potential therapeutic targets for the treatment and prevention of these diseases...
- HIV-1 protease and reverse transcriptase mutations for drug resistance surveillanceRobert W Shafer
Division of Infectious Diseases, Stanford University, Stanford, California, USA
AIDS 21:215-23. 2007..However, such programs will not produce comparable estimates unless a standardized list of drug-resistance mutations is used to define transmitted resistance...
- Feasibility of noncontact intracardiac ultrasound ablation and imaging catheter for treatment of atrial fibrillationSerena H Wong
Stanford University, Department of Electrical Engineering, Stanford, CA, USA
IEEE Trans Ultrason Ferroelectr Freq Control 53:2394-405. 2006..In simulations and proof-of-concept experiments, we show a 37 degrees C temperature rise in the lesion location and demonstrate the possibility of lesion imaging...
- Ancient DNA reveals Holocene loss of genetic diversity in a South American rodentYvonne L Chan
Department of Biological Sciences, Stanford University, 371 Serra Mall, Stanford, CA 94305 5020, USA
Biol Lett 1:423-6. 2005..Our results highlight the importance of non-anthropogenic factors in loss of diversity, including reductions in smaller mammals such as rodents...
- Bone and joint infections in childrenKathleen Gutierrez
Department of Pediatrics, Division of Pediatric Infectious Disease, Stanford University School of Medicine, Stanford, CA 94305, USA
Pediatr Clin North Am 52:779-94, vi. 2005..This article reviews current information regarding pathogenesis, epidemiology, and microbiology of pediatric bone and joint infections and the clinical presentation, diagnosis, and treatment of these infections...
- NOVEL APPROACHES TO ANTITUMOR AND ANTIVIRAL AGENTSBARRY TROST; Fiscal Year: 2004..By accessing a very diverse range of structural types, the best opportunities to discover new therapeutic agents arise. ..
- Synthesis of Macrolides, Steroids, Cyclopentanoids, etc.BARRY TROST; Fiscal Year: 2006..These new synthetic methods apply to many structural types beyond those illustrated and constitutes a significant to gain access to complex molecular targets more easily. ..
- NOVEL SYNTHETIC APPROACHES TO ANTITUMOR COMPOUNDSBARRY TROST; Fiscal Year: 1992..A strategy to one family of tumor promoters represented by teleocidin explores the concept of chemical chameleons. In most cases, the strategy also considers the problem of absolute stereochemistry...
- Novel Approaches for Antitumor and Antiviral AgentsBarry M Trost; Fiscal Year: 2010..This proposal helps to address this key challenge by developing the underlying initial technology within classes of compounds having demonstrably antitumor or antiviral activities. ..
- NOVEL APPROACHES TO ANTITUMOR AND ANTIVIRAL AGENTSBARRY TROST; Fiscal Year: 2000..Equally important, new avenues to vary structure around these cores in order to establish structure-activity relationships with the aim to create better therapeutic agents become available. ..
- Synthesis of Macrolides. Steroids, Cyclopentanoids, etcBARRY TROST; Fiscal Year: 2005..This new concept sets the stage for solutions to a long standing problem, the ion channel blockers, the grayanotoxins. as well as the more recently discovered rameswaralide, a potent antiinflamatory. ..
- SYNTHESIS OF MACROCYCLES STEROIDS CYCLOPENTANOIDS ETCBARRY TROST; Fiscal Year: 2001..Ring expansion methods may convert these cores into the taxoid skeleton with appropriate functionality at key points for analog development. ..
- NOVEL APPROACHES TO ANTITUMOR AND ANTIVIRAL AGENTSBARRY TROST; Fiscal Year: 1993..The diversity of the challenges posed by antiviral and antitumor agents represent highly meaningful tests of their use...
- Synthesis of Macrolides, Steroids, Cyclopentanoids, etc.BARRY TROST; Fiscal Year: 2009..These new synthetic methods apply to many structural types beyond those illustrated and constitutes a significant to gain access to complex molecular targets more easily. ..
- Synthesis of Macrolides, Steroids, Cyclopentanoids, etc.BARRY TROST; Fiscal Year: 2007..These new synthetic methods apply to many structural types beyond those illustrated and constitutes a significant to gain access to complex molecular targets more easily. ..
- NOVEL APPROACHES TO ANTITUMOR AND ANTIVIRAL AGENTSBARRY TROST; Fiscal Year: 2007..By expediting access to very diverse arrays of structural types, the best opportunities to discover new therapeutic agents arise. ..
- Synthesis of Macrolides, Steroids, Cyclopentanoids, etc.BARRY TROST; Fiscal Year: 2007
- SYNTHETIC STUDIES ON TUMOR PROMOTERS AND INHIBITORSPAUL ANTHONY WENDER; Fiscal Year: 2010..The project provides for the creation of fundamental knowledge of broad potential utility and at the same time new approaches and agents to address unmet clinical needs in cancer, HIV/AIDS and other diseases. ..
- SYNTHETIC STUDIES RELATED TO CANCER RESEARCH/TREATMENTPaul Wender; Fiscal Year: 2005..Overall, this research program is expected to be of significant value in chemistry, biology, and medicine. ..
- SYNTHETIC STUDIES RELATED TO CANCER RESEARCH/TREATMENTPaul Wender; Fiscal Year: 1990..A new enolate chemistry will be developed in connection with a general approach to cannabinoid synthesis...
- SYNTHETIC STUDIES RELATED TO CANCER RESEARCH/TREATMENTPaul Wender; Fiscal Year: 1993..A final project entails completion of studies on the synthesis of aplysiatoxin. Overall, this research program is expected to be of significant value in chemistry, biology, and medicine...
- SYNTHETIC STUDIES RELATED TO CANCER RESEARCH/TREATMENTPaul Wender; Fiscal Year: 2000..Overall, this research program is expected-to be of significant value in chemistry, biology, and medicine. ..