Jie J Zheng

Summary

Affiliation: St. Jude Children's Research Hospital
Country: USA

Publications

  1. pmc Genome-wide network analysis of Wnt signaling in three pediatric cancers
    Ju Bao
    Department of Structural Biology, St Jude Children s Research Hospital, Memphis, TN 38105
    Sci Rep 3:2969. 2013
  2. pmc PDZ domains and their binding partners: structure, specificity, and modification
    Ho Jin Lee
    Department of Structural Biology, St, Jude Children s Research Hospital, Memphis, TN 38105, USA
    Cell Commun Signal 8:8. 2010
  3. ncbi request reprint An antagonist of dishevelled protein-protein interaction suppresses beta-catenin-dependent tumor cell growth
    Naoaki Fujii
    Department of Pharmaceutical Chemistry, Thoracic Oncology Labratory, University of California San Francisco, and Department of Structural Biology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Cancer Res 67:573-9. 2007
  4. ncbi request reprint The structural biology of type II fatty acid biosynthesis
    Stephen W White
    Department of Structural Biology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Annu Rev Biochem 74:791-831. 2005
  5. ncbi request reprint Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled
    Hing C Wong
    Department of Structural Biology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Mol Cell 12:1251-60. 2003
  6. ncbi request reprint Identification of a specific inhibitor of the dishevelled PDZ domain
    Jufang Shan
    Department of Structural Biology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Biochemistry 44:15495-503. 2005
  7. ncbi request reprint Interaction between the internal motif KTXXXI of Idax and mDvl PDZ domain
    Timothy B C London
    Department of Structural Biology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Biochem Biophys Res Commun 322:326-32. 2004
  8. ncbi request reprint Key residues responsible for acyl carrier protein and beta-ketoacyl-acyl carrier protein reductase (FabG) interaction
    Yong Mei Zhang
    Department of Infectious Diseases, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    J Biol Chem 278:52935-43. 2003
  9. pmc Structural insights into the role of the Smoothened cysteine-rich domain in Hedgehog signalling
    Rajashree Rana
    1 Department of Structural Biology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA 2 Integrated Program in Biomedical Sciences, University of Tennessee Health Science Center, Memphis, Tennessee 38105, USA
    Nat Commun 4:2965. 2013
  10. ncbi request reprint Crystal structures of the Dab homology domains of mouse disabled 1 and 2
    Mikyung Yun
    Department of Structural Biology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    J Biol Chem 278:36572-81. 2003

Collaborators

  • Yong Mei Zhang
  • C O Rock
  • Naoaki Fujii
  • Iwao Mikami
  • STEPHEN W contact WHITE
  • Xiaoyan Qiu
  • Yan Li
  • J Zhang
  • Ling Li
  • Xin Xia Tian
  • Buyong Ma
  • Ho Jin Lee
  • Jiang Feng You
  • Ju Bao
  • Cong Rong Liu
  • Hui Ying He
  • Hing C Wong
  • Cristina D Guibao
  • Rajashree Rana
  • Jie Liang Wang
  • Dianqing Wu
  • Jun yu Ning
  • Wei Gang Fang
  • Ke Wang
  • Gaohua Liu
  • Ru Zhou
  • Zheng Yuan
  • Nurit Haspel
  • Xiang Lin Cui
  • Meng Pan
  • Yu qing Deng
  • Craig M Bertolucci
  • Hongtao Ye
  • Jufang Shan
  • Shiyan Yan
  • Xiu ning Lu
  • Fei Pei
  • Jian Song
  • Yuanjun Zhao
  • De Li Shi
  • Chun shu Ma
  • Song Lin Liao
  • Yuan Gao
  • Peter Maye
  • Wan Jie Heng
  • Timothy B C London
  • J Bradley Dickerson
  • Youming Shao
  • Ling Ling Kong
  • Jian Ying Liu
  • Ba Bian
  • Mikyung Yun
  • Hao Hao Zhong
  • Stacey K Ogden
  • Suresh Marada
  • CANDACE E CARROLL
  • Christy R R Grace
  • Xiaofeng Li
  • Lin Yan
  • Ping Zheng
  • He Wang
  • Lijun Chen
  • Qingbin Xu
  • Guidong Dai
  • Jianguo Wu
  • Jing Su
  • Carlos Aleman
  • Haim Wolfson
  • David Zanuy
  • Ruth Nussinov
  • Jing Huang
  • Xiao hui Zhu
  • Weiping Li
  • Zhi Xin Li
  • Xiaoqing Zhao
  • Feng Xue
  • Pei Zhang
  • Guo Hui Li
  • Junmei Wang
  • Dong Sheng Zhang
  • Zifen Gao
  • Reiner Siebert
  • Ming Ma
  • Yun Ling
  • Sima Shirali
  • Rifat A Hamoudi
  • Andreas Chott
  • Shao min Yang
  • Hongxiang Liu
  • Peter G Isaacson

Detail Information

Publications44

  1. pmc Genome-wide network analysis of Wnt signaling in three pediatric cancers
    Ju Bao
    Department of Structural Biology, St Jude Children s Research Hospital, Memphis, TN 38105
    Sci Rep 3:2969. 2013
    ..Our results suggest that the cancer cells maintain a normal level of Wnt signaling by developing multiple mutations...
  2. pmc PDZ domains and their binding partners: structure, specificity, and modification
    Ho Jin Lee
    Department of Structural Biology, St, Jude Children s Research Hospital, Memphis, TN 38105, USA
    Cell Commun Signal 8:8. 2010
    ..A better understanding of PDZ protein-protein interaction networks and regulatory mechanisms will improve our knowledge of many cellular and biological processes...
  3. ncbi request reprint An antagonist of dishevelled protein-protein interaction suppresses beta-catenin-dependent tumor cell growth
    Naoaki Fujii
    Department of Pharmaceutical Chemistry, Thoracic Oncology Labratory, University of California San Francisco, and Department of Structural Biology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Cancer Res 67:573-9. 2007
    ..FJ9 is thus among the first non-peptide inhibitors to show therapeutic efficacy through disruption of PDZ protein-protein interactions...
  4. ncbi request reprint The structural biology of type II fatty acid biosynthesis
    Stephen W White
    Department of Structural Biology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Annu Rev Biochem 74:791-831. 2005
    ..These structures are also a valuable resource to guide antibacterial drug discovery...
  5. ncbi request reprint Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled
    Hing C Wong
    Department of Structural Biology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Mol Cell 12:1251-60. 2003
    ..Together, our results identify a missing molecular connection within the Wnt pathway. Differences in the binding affinity of the Dvl PDZ domain and its binding partners may be important in regulating signal transduction by Dvl...
  6. ncbi request reprint Identification of a specific inhibitor of the dishevelled PDZ domain
    Jufang Shan
    Department of Structural Biology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Biochemistry 44:15495-503. 2005
    ..This compound provides a basis for rational design of high-affinity inhibitors of the PDZ domain, which can block Wnt signaling by interrupting the Fz-Dvl interaction...
  7. ncbi request reprint Interaction between the internal motif KTXXXI of Idax and mDvl PDZ domain
    Timothy B C London
    Department of Structural Biology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Biochem Biophys Res Commun 322:326-32. 2004
    ..Such internal motif identified in this study suggests a new type of sequence motif recognition for Dvl PDZ domain...
  8. ncbi request reprint Key residues responsible for acyl carrier protein and beta-ketoacyl-acyl carrier protein reductase (FabG) interaction
    Yong Mei Zhang
    Department of Infectious Diseases, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    J Biol Chem 278:52935-43. 2003
    ..The specific FabG-ACP interactions involve the most conserved ACP residues, which accounts for the ability of ACPs and the type II proteins from different species to function interchangeably...
  9. pmc Structural insights into the role of the Smoothened cysteine-rich domain in Hedgehog signalling
    Rajashree Rana
    1 Department of Structural Biology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA 2 Integrated Program in Biomedical Sciences, University of Tennessee Health Science Center, Memphis, Tennessee 38105, USA
    Nat Commun 4:2965. 2013
    ..Our results highlight a function of the Smo CRD, demonstrating its role in binding to small-molecule modulators. ..
  10. ncbi request reprint Crystal structures of the Dab homology domains of mouse disabled 1 and 2
    Mikyung Yun
    Department of Structural Biology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    J Biol Chem 278:36572-81. 2003
    ..These findings suggest that simultaneous interaction of the rigid DH domain with the NPXY sequence and PtdIns-4,5-P2 plays a role in the attachment of Dab proteins to the APP/lipoprotein receptors and phosphoinositide-rich membranes...
  11. pmc Structural features of the focal adhesion kinase-paxillin complex give insight into the dynamics of focal adhesion assembly
    Craig M Bertolucci
    Department of Structural Biology, MS 311, St Jude Children s Research Hospital, 332 N Lauderdale, Memphis, TN 38105, USA
    Protein Sci 14:644-52. 2005
    ....
  12. pmc Structural insight into the mechanisms of targeting and signaling of focal adhesion kinase
    Gaohua Liu
    Department of Structural Biology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Mol Cell Biol 22:2751-60. 2002
    ..Such conformational change is proposed to precede departure of FAK from focal adhesions, which starts focal adhesion turnover...
  13. ncbi request reprint The solution structure of acyl carrier protein from Mycobacterium tuberculosis
    Hing C Wong
    Department of Structural Biology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    J Biol Chem 277:15874-80. 2002
    ....
  14. ncbi request reprint Human epithelial cancers secrete immunoglobulin g with unidentified specificity to promote growth and survival of tumor cells
    Xiaoyan Qiu
    Beijing University Center for Human Disease Genomics, 38 Xue Yuan Road, 100083 Beijing, China
    Cancer Res 63:6488-95. 2003
    ..Prevalent expression of IgG in human carcinomas and its growth-promoting functions may have important implications in growth regulation and targeted therapy of human cancers...
  15. ncbi request reprint [Immunoglobulin expression in colon cancer cell line HT-29 and its biological activities]
    Yu qing Deng
    Peking University Center for Human Disease Genomics, Beijing 100083, China
    Zhonghua Zhong Liu Za Zhi 28:88-91. 2006
    ..To determine the expression of immunoglobulins in HT-29 cells (an established colon cancer cell line, and explore their effect on the biological activities of the cancer cells.)..
  16. ncbi request reprint Establishment of the mouse model by rabbit antiserum specific to EC1-2 or EC3-4 epitopes for studying the pathogenesis of pemphigus vulgaris
    Meng Pan
    Department of Dermatology, Rui Jin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China, 200025
    Immunol Invest 35:47-61. 2006
    ..A novel PV mouse model was established by treatment with the specific rabbit antiserum. These data confirmed that both EC1-2 and EC3-4 are pathogenic epitopes in PVA, but EC1-2 is more dominant...
  17. ncbi request reprint Therapeutic effect of Fe2O3 nanoparticles combined with magnetic fluid hyperthermia on cultured liver cancer cells and xenograft liver cancers
    Shiyan Yan
    Department of Pathology and Pathophysiology, Institute of Molecular Pathology, School of Basic Medical Sciences, Southeast University, Nanjing 210096, Jiangsu, P R China
    J Nanosci Nanotechnol 5:1185-92. 2005
    ..However, the mechanism remains to be further investigated...
  18. ncbi request reprint [SHP2 and MKP5 in P2Y purinergic receptor-mediated prostate cancer invasion]
    Hui Ying He
    Department of Pathology, Health Science Center, Peking University, Beijing 100083, China
    Zhonghua Bing Li Xue Za Zhi 34:288-92. 2005
    ....
  19. ncbi request reprint Consensus features in amyloid fibrils: sheet-sheet recognition via a (polar or nonpolar) zipper structure
    Jie Zheng
    Basic Research Program, SAIC Frederick, Inc, Center for Cancer Research Nanobiology Program, NCI Frederick, Frederick, MD 21702, USA
    Phys Biol 3:P1-4. 2006
    ....
  20. pmc Changing the charge distribution of beta-helical-based nanostructures can provide the conditions for charge transfer
    Nurit Haspel
    School of Computer Science Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978, Israel
    Biophys J 93:245-53. 2007
    ....
  21. pmc Modeling the Alzheimer Abeta17-42 fibril architecture: tight intermolecular sheet-sheet association and intramolecular hydrated cavities
    Jie Zheng
    Basic Research Program, SAIC Frederick Center for Cancer Research, Nanobiology Program, NCI Frederick, Frederick, Maryland 21702, USA
    Biophys J 93:3046-57. 2007
    ..Thus, we propose that Abeta fiber architecture consists of alternating layers of tight packing and hydrated cavities running along the fibrillar axis, which might be possibly detected by high-resolution imaging...
  22. ncbi request reprint [Correlation of expression of RhoC with invasiveness of prostate cancer cell line PC-3M in vitro]
    Zheng Yuan
    Department of Pathology, Health Science Center, Peking University, Beijing 100083, China
    Zhonghua Yi Xue Za Zhi 88:51-5. 2008
    ..To investigate the expression of RhoC in prostate cancer cells with different metastatic potential and the correlation with invasiveness...
  23. doi request reprint Cardioprotective effect of fluvastatin on isoproterenol-induced myocardial infarction in rat
    Ru Zhou
    Department of Pharmacology, School of Basic Medical Science, Ningxia Medical College, 692 Shengli Street, Yinchuan, Ningxia, 750004, PR China
    Eur J Pharmacol 586:244-50. 2008
    ..05). Our results suggest that fluvastatin has a significant effect on the protection of heart against isoproterenol-induced myocardial infarction through maintaining endogenous antioxidant enzyme activities...
  24. pmc Characterization of the Kremen-binding site on Dkk1 and elucidation of the role of Kremen in Dkk-mediated Wnt antagonism
    Ke Wang
    State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China
    J Biol Chem 283:23371-5. 2008
    ..These results suggest that Kremen may not be essential for Dkk1-mediated Wnt antagonism and that Kremen may only play a role when cells express a high level of LRP5/6...
  25. ncbi request reprint Effects of cotransfection of antisense-EGFR and wild-type PTEN cDNA on human glioblastoma cells
    Xin Xia Tian
    Department of Pathology, Peking University Health Science Center, Beijing 100083, China
    Neuropathology 26:178-87. 2006
    ..This approach may prove useful as an adjunct therapy in the treatment of glioblastomas...
  26. ncbi request reprint [The association of HeLa cell apoptosis induced by arsenic trioxide with the down-regulation of HPV18 E6 oncogene and inhibition of telomerase activity]
    Xiu ning Lu
    Department of Obstetrics and Gynecology, Yangzhou First People s Hospital, Jiangsu Province, Yangzhou 225001, China
    Zhonghua Zhong Liu Za Zhi 27:265-8. 2005
    ..To study the effect of As2O3 induction of HeLa cell apoptosis on HPV18 E6 expression and telomerase activity...
  27. ncbi request reprint Transcriptional upregulation of DNA polymerase beta by TEIF
    Yuanjun Zhao
    Department of Pathology, Health Science Center, Peking University, Beijing 100083, China
    Biochem Biophys Res Commun 333:908-16. 2005
    ..The data may provide new clue to the elucidation of beta-pol overexpression in cancers and also a functional link between beta-pol and telomerase...
  28. ncbi request reprint Expression of CD44v6 gene in normal human peripheral blood
    Jian Song
    Department of Pathology, Medical School of Southeast University, Nanjing 210009, Jiangsu Province, China
    World J Gastroenterol 11:3591-4. 2005
    ..To investigate if CD44v6 could be used as a molecular marker of cancer progression and metastasis through the detection of CD44v6 gene expression in normal human peripheral blood...
  29. ncbi request reprint [Down-regulation of metastatic phenotype in human melanoma cells by controlled expression of anti-sense matrix metalloproteinase 9]
    Ling Ling Kong
    Department of Pathology, Health Science Center, Peking University, Beijing 100083, China
    Zhonghua Bing Li Xue Za Zhi 32:137-41. 2003
    ..To investigate the correlation between matrix metalloproteinase 9 (MMP-9) expression and tumor invasion and metastasis as well, and to explore the potential application of controlled expression of target gene in tumor gene therapy...
  30. ncbi request reprint [The effects of TMSG-1 gene transfection on metastatic phenotype of pg cancer cells]
    Ba Bian
    Department of Pathology, Peking University School of Basic Medical Sciences, Beijing 100083, China
    Beijing Da Xue Xue Bao 35:18-22. 2003
    ..To observe the relationship between TMSG-1 gene and tumor metastatic phenotype...
  31. ncbi request reprint Disruption of an intersubunit interaction underlies Ca2+-calmodulin modulation of cyclic nucleotide-gated channels
    Jie Zheng
    Howard Hughes Medical Institute and Department of Physiology and Biophysics, University of Washington School of Medicine, Seattle, Washington 98195 7290, USA
    J Neurosci 23:8167-75. 2003
    ..The quaternary arrangement presents a structural framework for understanding the molecular mechanism of olfactory adaptation...
  32. ncbi request reprint [Mechanism of antisense epidermal growth factor receptor cDNA in growth suppression of glioblastomas cells]
    Xin Xia Tian
    Department of Pathology, Health Science Center, Peking University, Beijing 100083, China
    Zhonghua Bing Li Xue Za Zhi 32:242-6. 2003
    ..To study the mechanism of antisense epidermal growth factor receptor cDNA in growth suppression of glioblastomas cells...
  33. ncbi request reprint [Mechanism of the mitogen-activated protein kinase phosphatase-5 regulating the growth and invasion of a human prostate cancer cell line]
    Hui Ying He
    Department of Pathology, Peking University Health Science Center, Beijing 100083, China
    Zhonghua Yi Xue Za Zhi 83:1812-7. 2003
    ....
  34. ncbi request reprint Differential thymosin beta 10 expression levels and actin filament organization in tumor cell lines with different metastatic potential
    Cong Rong Liu
    Department of Pathology, Health Science Center, Peking University, Beijing 100083, China
    Chin Med J (Engl) 117:213-8. 2004
    ..To investigate the differential expression levels of thymosin beta 10 (T beta 10) and the corresponding changes of actin filament organization in human tumor cell lines with different metastatic potential...
  35. ncbi request reprint [Thymosin beta10 expression and actin filament organization in tumor cell lines with different metastatic potential]
    Cong Rong Liu
    Department of Pathology, Health Science Center, Peking University, Beijing 100083, China
    Zhonghua Bing Li Xue Za Zhi 33:67-71. 2004
    ..To investigate the expression of thymosin beta10 (Tbeta10) and related changes of actin filament organization in human tumor cell lines with different metastatic potential...
  36. ncbi request reprint Multiple mechanisms for Wnt11-mediated repression of the canonical Wnt signaling pathway
    Peter Maye
    Department of Genetics and Developmental Biology, University of Connecticut Health Center, Farmington, Connecticut 06030, USA
    J Biol Chem 279:24659-65. 2004
    ..Knockdown of Wnt11 expression using siRNA resulted in increased LEF-1 reporter activity, thus indicating that Wnt11-mediated suppression of canonical signaling exists in vivo...
  37. pmc Rational design and characterization of a Rac GTPase-specific small molecule inhibitor
    Yuan Gao
    Division of Experimental Hematology, Children s Hospital Research Foundation, Cincinnati, OH 45229, USA
    Proc Natl Acad Sci U S A 101:7618-23. 2004
    ..Thus, NSC23766 constitutes a Rac-specific small-molecule inhibitor that could be useful to study the role of Rac in various cellular functions and to reverse tumor cell phenotypes associated with Rac deregulation...
  38. pmc The LRP5 high-bone-mass G171V mutation disrupts LRP5 interaction with Mesd
    Yazhou Zhang
    Department of Genetics and Developmental Biology, University of Connecticut Health Center, 263 Farmington Ave, Farmington, CT 06410, USA
    Mol Cell Biol 24:4677-84. 2004
    ....
  39. ncbi request reprint [The molecular interaction between P53 and telomeric repeat binding protein 1 in vitro]
    Ling Li
    Department of Pathology, Peking University School of Basic Medical Sciences, Beijing 100083, China
    Beijing Da Xue Xue Bao 36:510-3. 2004
    ..This study aimed to clarify the molecular regulation of P53 through telomere pathway by the investigation of molecular interaction between P53 and the main telomere associated protein telomeric repeat binding protein 1(TRBP1) in vitro...
  40. ncbi request reprint MALT lymphoma with t(14;18)(q32;q21)/IGH-MALT1 is characterized by strong cytoplasmic MALT1 and BCL10 expression
    Hongtao Ye
    Department of Pathology, University of Cambridge, Cambridge, UK
    J Pathol 205:293-301. 2005
    ..These results show that MALT1 expression pattern is identical to that of BCL10 in normal lymphoid tissues but varies in MALT lymphomas, with high cytoplasmic expression of both MALT1 and BCL10 characterizing those with t(14;18)(q32;q21)...
  41. ncbi request reprint [Monoclonal antibodies against human tumor metastasis suppressor gene-1 TMSG-1: preparation, characterization and application]
    Fei Pei
    Department of Pathology, Health Science Center, Peking University, Beijing 100083, China
    Zhonghua Bing Li Xue Za Zhi 34:15-21. 2005
    ....
  42. ncbi request reprint [In vitro binding of p53 and telomeric repeat factor 2]
    Ling Li
    Department of Pathology, Health Science Center, Peking University, Beijing 100083, China
    Zhonghua Bing Li Xue Za Zhi 34:88-91. 2005
    ..To clarify the regulation of p53 through telomere pathway by investigating the molecular interaction between p53 and the main telomere-associated protein Telomeric Repeat Factor 2 (TRF2) in vitro...
  43. pmc Strong repulsive forces between protein and oligo (ethylene glycol) self-assembled monolayers: a molecular simulation study
    Jie Zheng
    Department of Chemical Engineering, University of Washington, Seattle, Washington 98195, USA
    Biophys J 89:158-66. 2005
    ..Results show that a tightly bound water layer adjacent to the OEG-SAMs is mainly responsible for the large repulsive hydration force...
  44. ncbi request reprint [Effects of two variants of ING1 expression on tumor cell growth regulation]
    Jian Ying Liu
    Department of Pathology, Health Science Center, Peking University, Beijing 100083, China
    Zhonghua Bing Li Xue Za Zhi 32:48-51. 2003
    ..To study effects of alternative transcripts of ING1 transfection on human cancer cell lines...

Research Grants15

  1. STRUCTURAL INVESTIGATION OF FOCAL ADHESION MOLECULES
    Jie Zheng; Fiscal Year: 2006
    ..abstract_text> ..
  2. MOLECULAR BASIS OF THE WNT SIGNALING PATHWAY
    Jie Zheng; Fiscal Year: 2001
    ....
  3. MOLECULAR BASIS OF THE WNT SIGNALING PATHWAY
    Jie Zheng; Fiscal Year: 2002
    ....
  4. STRUCTURAL INVESTIGATION OF FOCAL ADHESION MOLECULES
    Jie Zheng; Fiscal Year: 2007
    ..abstract_text> ..
  5. Mechanisms of Different Wnt Signals
    Jie Zheng; Fiscal Year: 2009
    ..These findings may also be useful in formulating rational approaches to the development of novel pharmaceutical agents that can interfere with specific Wnt signaling events that contribute to human diseases. ..
  6. Mechanisms of Different Wnt Signals
    Jie Zheng; Fiscal Year: 2007
    ..These findings may also be useful in formulating rational approaches to the development of novel pharmaceutical agents that can interfere with specific Wnt signaling events that contribute to human diseases. ..
  7. MOLECULAR BASIS OF THE WNT SIGNALING PATHWAY
    Jie Zheng; Fiscal Year: 2005
    ....
  8. STRUCTURAL INVESTIGATION OF FOCAL ADHESION MOLECULES
    Jie Zheng; Fiscal Year: 2005
    ..abstract_text> ..
  9. MOLECULAR BASIS OF THE WNT SIGNALING PATHWAY
    Jie Zheng; Fiscal Year: 2000
    ....
  10. STRUCTURAL INVESTIGATION OF FOCAL ADHESION MOLECULES
    Jie Zheng; Fiscal Year: 2005
    ..abstract_text> ..
  11. MOLECULAR BASIS OF THE WNT SIGNALING PATHWAY
    Jie Zheng; Fiscal Year: 2004
    ....
  12. STRUCTURAL INVESTIGATION OF FOCAL ADHESION MOLECULES
    Jie Zheng; Fiscal Year: 2004
    ..abstract_text> ..
  13. MOLECULAR BASIS OF THE WNT SIGNALING PATHWAY
    Jie Zheng; Fiscal Year: 2003
    ....
  14. Mechanisms of Different Wnt Signals
    Jie J Zheng; Fiscal Year: 2010
    ..These findings may also be useful in formulating rational approaches to the development of novel pharmaceutical agents that can interfere with specific Wnt signaling events that contribute to human diseases. ..