Affiliation: St. Jude Children's Research Hospital
- Inherited NUDT15 Variant Is a Genetic Determinant of Mercaptopurine Intolerance in Children With Acute Lymphoblastic LeukemiaJun J Yang
Jun J Yang, Wenjian Yang, Chengcheng Liu, Cheng Cheng, Deqing Pei, Kristine R Crews, Nancy Kornegay, William E Evans, Ching Hon Pui, and Mary V Relling, St Jude Children s Research Hospital, Memphis, TN and Wendy Landier, Lindsey Hageman, Yanjun Chen, F Lennie Wong, and Smita Bhatia, City of Hope, Duarte, CA
J Clin Oncol 33:1235-42. 2015..Mercaptopurine (MP) is the mainstay of curative therapy for acute lymphoblastic leukemia (ALL). We performed a genome-wide association study (GWAS) to identify comprehensively the genetic basis of MP intolerance in children with ALL...
- Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populationsHeng Xu
Department of Pharmaceutical Sciences, St Jude Children s Research Hospital, Memphis, TN 38105 3678, USA
J Natl Cancer Inst 105:733-42. 2013..Although accumulating evidence indicates inherited predisposition to ALL, the genetic basis of ALL susceptibility in diverse ancestry has not been comprehensively examined...
- ARID5B genetic polymorphisms contribute to racial disparities in the incidence and treatment outcome of childhood acute lymphoblastic leukemiaHeng Xu
St Jude Children s Research Hospital, Memphis, TN 38105 3678, USA
J Clin Oncol 30:751-7. 2012..We sought to determine the contribution of ARID5B single nucleotide polymorphisms (SNPs) to racial disparities in ALL susceptibility and treatment outcome...
- Folate-linked drugs for the treatment of cancer and inflammatory diseasesJun Yang
St Jude Children s Research Hospital, Memphis, TN, USA
Subcell Biochem 56:163-79. 2012....