Richard John Webby

Summary

Affiliation: St. Jude Children's Research Hospital
Country: USA

Publications

  1. pmc A contributing role for anti-neuraminidase antibodies on immunity to pandemic H1N1 2009 influenza A virus
    Glendie Marcelin
    Department of Infectious Diseases, Division of Virology, St Jude Children s Research Hospital, Memphis, Tennessee, United States of America
    PLoS ONE 6:e26335. 2011
  2. pmc H3N2 influenza virus transmission from swine to turkeys, United States
    Young K Choi
    Chungbuk National University, Cheongju, Republic of Korea
    Emerg Infect Dis 10:2156-60. 2004
  3. pmc Pathogenicity and transmissibility of North American triple reassortant swine influenza A viruses in ferrets
    Subrata Barman
    Division of Virology, Department of Infectious Diseases, St Jude Children s Research Hospital, Memphis, Tennessee, United States of America
    PLoS Pathog 8:e1002791. 2012
  4. pmc Multiple reassortment between pandemic (H1N1) 2009 and endemic influenza viruses in pigs, United States
    Mariette F Ducatez
    Department of Infectious Diseases, St Jude Children s Research Hospital, 262 Danny Thomas Pl, Memphis, TN 38105 3678, USA
    Emerg Infect Dis 17:1624-9. 2011
  5. pmc Influenza A (H15N4) virus isolation in Western Siberia, Russia
    Mariya V Sivay
    State Research Center of Virology and Biotechnology Vector, Novosibirsk Region, Koltsovo, Russia
    J Virol 87:3578-82. 2013
  6. pmc Genetic analysis of influenza B viruses isolated in Uganda during the 2009-2010 seasons
    Denis K Byarugaba
    College of Veterinary Medicine, Makerere University, P, O, Box 7062, Kampala, Uganda
    Virol J 10:11. 2013
  7. pmc Passive immunoprophylaxis and therapy with humanized monoclonal antibody specific for influenza A H5 hemagglutinin in mice
    Brendon J Hanson
    Defence Medical and Environmental Research Institute, DSO National Laboratories, Singapore 117510
    Respir Res 7:126. 2006
  8. pmc Role of viral hemagglutinin glycosylation in anti-influenza activities of recombinant surfactant protein D
    Kevan L Hartshorn
    Department of Medicine, Boston University School of Medicine, Boston MA, USA
    Respir Res 9:65. 2008
  9. pmc Prospective study of avian influenza transmission to humans in Egypt
    Ghazi Kayali
    Division of Virology, Department of Infectious Diseases, St Jude Children s Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA
    BMC Public Health 10:685. 2010
  10. pmc Protocol: transmission and prevention of influenza in Hutterites: zoonotic transmission of influenza A: swine & swine workers
    Margaret L Russell
    Department of Community Health Sciences, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta T2N 4N1, Canada
    BMC Public Health 9:420. 2009

Research Grants

Collaborators

  • Robert G Webster
  • David Wang
  • E I Tuomanen
  • Jerold E Rehg
  • Sagar M Goyal
  • J A Richt
  • Yi Guan
  • Janet E McElhaney
  • Mariette F Ducatez
  • Glendie Marcelin
  • Ghazi Kayali
  • Mariya V Sivay
  • Denis K Byarugaba
  • Subrata Barman
  • Marie Gramer
  • Adam Rubrum
  • Thomas P Fabrizio
  • Ali H Ellebedy
  • A H Ellebedy
  • Margaret L Russell
  • Adrianus C M Boon
  • Ashley Webb
  • Kevan L Hartshorn
  • Brendon J Hanson
  • Young K Choi
  • Scott Krauss
  • Bernard Erima
  • Fred Wabwire-Mangen
  • Vasiliy Y Marchenko
  • Monica Millard
  • Tatiana Baranovich
  • Edison A Mworozi
  • Derrick Mimbe
  • Josephine Bwogi
  • Lukwago L
  • Kirill A Sharshov
  • Samuel K Martin
  • Bridget Sharp
  • Elena A Govorkova
  • Aleksander M Shestopalov
  • Hannah Kibuuka
  • Jasmine C Turner
  • Gene A Erickson
  • Petr S Krylov
  • Patrick Seiler
  • John Franks
  • Charles J Russell
  • Jerry R Aldridge
  • Rebecca Dubois
  • Ben Hause
  • Susu Duan
  • Randy Simonson
  • Daniel Darnell
  • Kevin Juleen
  • Zhipeng Cai
  • Evelyn Stigger-Rosser
  • James Lowe
  • Jeri Carol Crumpton
  • Jonathan A McCullers
  • Hazem E Ghoneim
  • Zhiping Ye
  • Christy Brockwell-Staats
  • Xiu Feng Wan
  • Malik Peiris
  • CESAR CORZO
  • Henju Marjuki
  • Paul G Thomas
  • Esmat A El-Ghafar
  • Scott A Brown
  • Xiaoping Xiong
  • Thomas H Oguin
  • Mohamed A Ali
  • Lobna S Sherif
  • Lorraine Moss
  • Pam Singh
  • Mark Loeb
  • Kevin Fonseca
  • Julia Keenliside
  • Rodney J Moreland
  • Ronald K Scheule
  • Erika C Crouch
  • Tesfaldet Tecle
  • Clark Pan
  • Mitchell R White
  • Susan Boucher
  • Eng Eong Ooi
  • Angeline P C Lim
  • Han S Joo
  • Jee H Lee
  • Gene Erickson

Detail Information

Publications19

  1. pmc A contributing role for anti-neuraminidase antibodies on immunity to pandemic H1N1 2009 influenza A virus
    Glendie Marcelin
    Department of Infectious Diseases, Division of Virology, St Jude Children s Research Hospital, Memphis, Tennessee, United States of America
    PLoS ONE 6:e26335. 2011
    ..The impact of antibodies to the neuraminidase (NA) of seasonal influenza A viruses to cross-immunity against pH1N1 infection is unknown...
  2. pmc H3N2 influenza virus transmission from swine to turkeys, United States
    Young K Choi
    Chungbuk National University, Cheongju, Republic of Korea
    Emerg Infect Dis 10:2156-60. 2004
    ..The isolation of swine-like H3N2 influenza viruses from turkeys raises new concerns for the generation of novel viruses that could affect humans...
  3. pmc Pathogenicity and transmissibility of North American triple reassortant swine influenza A viruses in ferrets
    Subrata Barman
    Division of Virology, Department of Infectious Diseases, St Jude Children s Research Hospital, Memphis, Tennessee, United States of America
    PLoS Pathog 8:e1002791. 2012
    ..We conclude that the lineages of HA and NA may play a crucial role in the respiratory droplet transmissibility of these viruses. These findings have important implications for pandemic planning and warrant confirmation...
  4. pmc Multiple reassortment between pandemic (H1N1) 2009 and endemic influenza viruses in pigs, United States
    Mariette F Ducatez
    Department of Infectious Diseases, St Jude Children s Research Hospital, 262 Danny Thomas Pl, Memphis, TN 38105 3678, USA
    Emerg Infect Dis 17:1624-9. 2011
    ..These novel reassortant viruses highlight the increasing complexity of influenza viruses within pig populations and the frequency at which viral diversification occurs in this ecologically important viral reservoir...
  5. pmc Influenza A (H15N4) virus isolation in Western Siberia, Russia
    Mariya V Sivay
    State Research Center of Virology and Biotechnology Vector, Novosibirsk Region, Koltsovo, Russia
    J Virol 87:3578-82. 2013
    ....
  6. pmc Genetic analysis of influenza B viruses isolated in Uganda during the 2009-2010 seasons
    Denis K Byarugaba
    College of Veterinary Medicine, Makerere University, P, O, Box 7062, Kampala, Uganda
    Virol J 10:11. 2013
    ..Complete genome analysis of one influenza B virus and several gene segments of other influenza B viruses isolated from Uganda from May 2009 through December 2010 was therefore undertaken in this study...
  7. pmc Passive immunoprophylaxis and therapy with humanized monoclonal antibody specific for influenza A H5 hemagglutinin in mice
    Brendon J Hanson
    Defence Medical and Environmental Research Institute, DSO National Laboratories, Singapore 117510
    Respir Res 7:126. 2006
    ..Humanized monoclonal antibodies (mAbs) that neutralize H5N1 virus could be used as prophylaxis and treatment to aid in the containment of such a pandemic...
  8. pmc Role of viral hemagglutinin glycosylation in anti-influenza activities of recombinant surfactant protein D
    Kevan L Hartshorn
    Department of Medicine, Boston University School of Medicine, Boston MA, USA
    Respir Res 9:65. 2008
    ..Surfactant protein D (SP-D) plays an important role in innate defense against influenza A viruses (IAVs) and other pathogens...
  9. pmc Prospective study of avian influenza transmission to humans in Egypt
    Ghazi Kayali
    Division of Virology, Department of Infectious Diseases, St Jude Children s Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA
    BMC Public Health 10:685. 2010
    ..Our objective for this study is to answer these questions by estimating the prevalence and incidence rates of human cases and determine associated risk and protective factors in areas where H5N1 viruses are endemic...
  10. pmc Protocol: transmission and prevention of influenza in Hutterites: zoonotic transmission of influenza A: swine & swine workers
    Margaret L Russell
    Department of Community Health Sciences, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta T2N 4N1, Canada
    BMC Public Health 9:420. 2009
    ..This project also includes non-Hutterite swine farms that are experiencing swine respiratory illness...
  11. ncbi request reprint Responsiveness to a pandemic alert: use of reverse genetics for rapid development of influenza vaccines
    R J Webby
    Department of Infectious Diseases, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Lancet 363:1099-103. 2004
    ..Since traditional strategies of vaccine production were not viable, we sought to produce a candidate reference virus using reverse genetics...
  12. pmc Influenza vaccines
    A H Ellebedy
    Department of Infectious Diseases, St Jude Children s Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105 3678, USA
    Vaccine 27:D65-8. 2009
    ..Within the context of biodefense, the issue will be to reach a balance where some of the diversity of influenza viruses can be encompassed within a vaccine while maintaining an acceptable level of efficacy...
  13. ncbi request reprint Influenza vaccines
    Richard John Webby
    Department of Infectious Diseases, St Jude Children s Research Hospital, 332 N Lauderdale, Memphis, TN 38105, USA
    Front Biosci 13:4912-24. 2008
    ..In this review current and pending influenza vaccine technologies will be discussed in the context of both epidemic and pandemic influenza...
  14. ncbi request reprint Influenza viruses in animal wildlife populations
    R J Webby
    Department of Infectious Diseases, St Jude Children s Research Hospital, 332 N Lauderdale, Memphis, TN 38105 2794, USA
    Curr Top Microbiol Immunol 315:67-83. 2007
    ..Even questions as fundamental as which hosts can transmit viruses to humans remain unanswered so far...
  15. ncbi request reprint Multiple lineages of antigenically and genetically diverse influenza A virus co-circulate in the United States swine population
    R J Webby
    Division of Virology, Department of Infectious Diseases, MS 330, St Jude Children s Research Hospital, 332 N Lauderdale, Memphis, TN 38105, USA
    Virus Res 103:67-73. 2004
    ....
  16. pmc Extent of antigenic cross-reactivity among highly pathogenic H5N1 influenza viruses
    Mariette F Ducatez
    Department of Infectious Diseases, St Jude Children s Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105 3678, USA
    J Clin Microbiol 49:3531-6. 2011
    ..2-specific antisera detected most of the H5N1 antigens), ancestral strain A exhibited the widest reactivity pattern and hence was the best candidate diagnostic reagent for broad detection of H5N1 strains...
  17. pmc Fatal outcome of pandemic H1N1 2009 influenza virus infection is associated with immunopathology and impaired lung repair, not enhanced viral burden, in pregnant mice
    Glendie Marcelin
    Department of Infectious Diseases, Division of Virology, St Jude Children s Research Hospital, 262 Danny Thomas Place, Mail Stop 330, Memphis, TN 38105, USA
    J Virol 85:11208-19. 2011
    ..Therefore, immunopathology likely caused by elevated cellular recruitment is an implicated mechanism of severe pH1N1 infection in pregnant mice...
  18. pmc Contemporary seasonal influenza A (H1N1) virus infection primes for a more robust response to split inactivated pandemic influenza A (H1N1) Virus vaccination in ferrets
    Ali H Ellebedy
    Department of Infectious Diseases, St Jude Children s Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105 3678, USA
    Clin Vaccine Immunol 17:1998-2006. 2010
    ....

Research Grants2

  1. Therapeutic Monoclonal Antibodies to H5N1 Influenza
    Richard Webby; Fiscal Year: 2007
    ..The results of these studies will be the development of an effective, highly cross-reactive anti-influenza therapeutic for prevention and potentially for treatment of H5N1 infections. ..