P D Stein

Summary

Affiliation: St. Joseph Mercy Oakland Hospital
Country: USA

Publications

  1. ncbi request reprint Outcomes with retrievable inferior vena cava filters
    Muhammad Janjua
    Department of Internal Medicine, St Joseph Mercy Oakland, Pontiac, Michigan 48341 5023, USA
    J Invasive Cardiol 22:235-9. 2010
  2. pmc Enlarged right ventricle without shock in acute pulmonary embolism: prognosis
    Paul D Stein
    Department of Research, St Joseph Mercy Oakland Hospital, Pontiac, Mich 48341 5023, USA
    Am J Med 121:34-42. 2008
  3. doi request reprint Epidemiology and incidence: the scope of the problem and risk factors for development of venous thromboembolism
    Paul D Stein
    Department of Research, St Mary Mercy Hospital, Livonia, MI 48154, USA
    Crit Care Clin 27:907-32, vii. 2011
  4. doi request reprint Trends in case fatality rate in pulmonary embolism according to stability and treatment
    Paul D Stein
    Department of Research, St Mary Mercy Hospital, Livonia, Michigan, USA
    Thromb Res 130:841-6. 2012
  5. doi request reprint Pulmonary embolism and deep venous thrombosis following bariatric surgery
    Paul D Stein
    Department of Osteopathic Medical Specialties, Michigan State University College of Osteopathic Medicine, East Lansing, MI, USA
    Obes Surg 23:663-8. 2013
  6. doi request reprint Electrocardiogram in pneumonia
    Paul D Stein
    Department of Research, St Mary Mercy Hospital, Livonia, Michigan, USA
    Am J Cardiol 110:1836-40. 2012
  7. doi request reprint Impact of vena cava filters on in-hospital case fatality rate from pulmonary embolism
    Paul D Stein
    Department of Research, St Mary Mercy Hospital, Livonia, MI 48154, USA
    Am J Med 125:478-84. 2012
  8. doi request reprint Thrombolytic therapy in unstable patients with acute pulmonary embolism: saves lives but underused
    Paul D Stein
    Department of Research, St Mary Mercy Hospital, Livonia, Michigan 48154, USA
    Am J Med 125:465-70. 2012
  9. doi request reprint Case fatality rate with pulmonary embolectomy for acute pulmonary embolism
    Paul D Stein
    Department of Research, St Mary Mercy Hospital, Livonia, MI 48154, USA
    Am J Med 125:471-7. 2012
  10. doi request reprint Ancillary findings on CT pulmonary angiograms and abnormalities on chest radiographs in patients in whom pulmonary embolism was excluded
    Paul D Stein
    Department of Research, St Mary Mercy Hospital, Livonia, MI 48154, USA
    Clin Appl Thromb Hemost 18:201-5. 2012

Research Grants

Detail Information

Publications106 found, 100 shown here

  1. ncbi request reprint Outcomes with retrievable inferior vena cava filters
    Muhammad Janjua
    Department of Internal Medicine, St Joseph Mercy Oakland, Pontiac, Michigan 48341 5023, USA
    J Invasive Cardiol 22:235-9. 2010
    ..Formalized guidelines for follow up may increase the proportion of patients in whom retrieval is attempted. Half of the complications of IVC filters could have been avoided with retrieval within 3 months...
  2. pmc Enlarged right ventricle without shock in acute pulmonary embolism: prognosis
    Paul D Stein
    Department of Research, St Joseph Mercy Oakland Hospital, Pontiac, Mich 48341 5023, USA
    Am J Med 121:34-42. 2008
    ..We assessed the in-hospital mortality of hemodynamically stable patients with PE and RV enlargement...
  3. doi request reprint Epidemiology and incidence: the scope of the problem and risk factors for development of venous thromboembolism
    Paul D Stein
    Department of Research, St Mary Mercy Hospital, Livonia, MI 48154, USA
    Crit Care Clin 27:907-32, vii. 2011
    ..Epidemiologic data and new information on risk factors provide insight into making an informed clinical assessment and evaluation for antithrombotic prophylaxis...
  4. doi request reprint Trends in case fatality rate in pulmonary embolism according to stability and treatment
    Paul D Stein
    Department of Research, St Mary Mercy Hospital, Livonia, Michigan, USA
    Thromb Res 130:841-6. 2012
    ..To determine categories of patients with pulmonary embolism in whom therapy has been reducing or failing to reduce case fatality rate...
  5. doi request reprint Pulmonary embolism and deep venous thrombosis following bariatric surgery
    Paul D Stein
    Department of Osteopathic Medical Specialties, Michigan State University College of Osteopathic Medicine, East Lansing, MI, USA
    Obes Surg 23:663-8. 2013
    ..This study aimed to assess the prevalence of in-hospital PE, DVT, and venous thromboembolism (VTE) following bariatric surgery in the USA from 2007 to 2009...
  6. doi request reprint Electrocardiogram in pneumonia
    Paul D Stein
    Department of Research, St Mary Mercy Hospital, Livonia, Michigan, USA
    Am J Cardiol 110:1836-40. 2012
    ..ECG findings are similar to ECG abnormalities in PE and electrocardiogram cannot assist in the differential diagnosis...
  7. doi request reprint Impact of vena cava filters on in-hospital case fatality rate from pulmonary embolism
    Paul D Stein
    Department of Research, St Mary Mercy Hospital, Livonia, MI 48154, USA
    Am J Med 125:478-84. 2012
    ..The purpose of this investigation is to determine categories of patients with pulmonary embolism in whom vena cava filters reduce in-hospital case fatality rate...
  8. doi request reprint Thrombolytic therapy in unstable patients with acute pulmonary embolism: saves lives but underused
    Paul D Stein
    Department of Research, St Mary Mercy Hospital, Livonia, Michigan 48154, USA
    Am J Med 125:465-70. 2012
    ..We tested the hypothesis that thrombolytic therapy reduces case fatality rate in such patients...
  9. doi request reprint Case fatality rate with pulmonary embolectomy for acute pulmonary embolism
    Paul D Stein
    Department of Research, St Mary Mercy Hospital, Livonia, MI 48154, USA
    Am J Med 125:471-7. 2012
    ..There are insufficient data to assess the potential role of pulmonary embolectomy in patients with acute pulmonary embolism...
  10. doi request reprint Ancillary findings on CT pulmonary angiograms and abnormalities on chest radiographs in patients in whom pulmonary embolism was excluded
    Paul D Stein
    Department of Research, St Mary Mercy Hospital, Livonia, MI 48154, USA
    Clin Appl Thromb Hemost 18:201-5. 2012
    ..This suggests a need for ancillary findings on CT pulmonary angiograms to be described systematically. At present, however, plain chest radiographs in some patients show ancillary findings not reported on CT angiograms. [corrected]...
  11. doi request reprint Prognostic value of D-dimer in stable patients with pulmonary embolism
    Paul D Stein
    Department of Internal Medicine, College of Osteopathic Medicine, Michigan State University, East Lansing, MI, USA
    Clin Appl Thromb Hemost 17:E183-5. 2011
    ..9% (2 of 70) with D-dimer ≥5000 ng/mL (NS). Markedly elevated levels of D-dimer, therefore, did not indicate a high mortality from PE or all-cause mortality during hospitalization...
  12. doi request reprint Diagnosis and management of isolated subsegmental pulmonary embolism: review and assessment of the options
    Paul D Stein
    Department of Research, St Mary Mercy Hospital, Livonia, MI 48154, USA
    Clin Appl Thromb Hemost 18:20-6. 2012
    ..After fully informing patients, some may choose to be treated and some may choose not to be treated...
  13. doi request reprint Challenges in the diagnosis of acute pulmonary embolism
    Paul D Stein
    Department of Research, St Joseph Mercy Oakland Hospital, Pontiac, Mich, USA
    Am J Med 121:565-71. 2008
    ..A patient-specific approach to the diagnosis of pulmonary embolism can be taken safely in hemodynamically stable patients to increase efficiency and decrease cost and exposure to radiation...
  14. doi request reprint In the era of multislice CT, do we still need leg ultrasonography to diagnose pulmonary embolism?
    Paul D Stein
    Research Education at St Joseph Mercy Oakland Hospital in Pontiac, MI 48341 5023, USA
    Nat Clin Pract Cardiovasc Med 5:688-9. 2008
    ..There are several valid reasons for recommending or not recommending leg studies in patients with suspected pulmonary embolism, and the choice of diagnostic tests should be individualized on a patient-by-patient basis...
  15. doi request reprint Incidence of vena cava thrombosis in the United States
    Paul D Stein
    St Joseph Mercy Oakland Hospital, Pontiac, Michigan, USA
    Am J Cardiol 102:927-9. 2008
    ..07%). In conclusion, isolated vena cava thrombosis is an uncommon cause of pulmonary embolism but may be considered if the veins of the extremities show no deep venous thrombosis...
  16. doi request reprint Fat embolism syndrome
    Paul D Stein
    Department of Research, St Joseph Mercy Oakland Hospital, Pontiac, Michigan 48341 5023, USA
    Am J Med Sci 336:472-7. 2008
    ..To assess the incidence and risk factors for fat embolism syndrome...
  17. doi request reprint Incidence of amniotic fluid embolism: relation to cesarean section and to age
    Paul D Stein
    St Joseph Mercy Oakland Hospital, Pontiac, Michigan 48341 5023, USA
    J Womens Health (Larchmt) 18:327-9. 2009
    ..To determine the incidence of amniotic fluid embolism and the incidence as modified by cesarean section and age...
  18. pmc Diagnosis of pulmonary embolism in the coronary care unit
    Paul D Stein
    Department of Research, St Joseph Mercy Oakland Hospital, Pontiac, MI, USA
    Am J Cardiol 103:881-6. 2009
    ..In conclusion, the choice of diagnostic test depends on the clinical probability of PE, the condition of the patient, the availability of diagnostic tests, the risks of iodinated contrast material, radiation exposure, and cost...
  19. pmc Clinical characteristics of patients with acute pulmonary embolism: data from PIOPED II
    Paul D Stein
    Department of Research, St Joseph Mercy Oakland Hospital, Pontiac, Mich 48341 5023, USA
    Am J Med 120:871-9. 2007
    ....
  20. ncbi request reprint Usefulness of multidetector spiral computed tomography according to age and gender for diagnosis of acute pulmonary embolism
    Paul D Stein
    Department of Research, St Joseph Mercy Oakland Hospital, Pontiac, Michigan, USA
    Am J Cardiol 99:1303-5. 2007
    ..In conclusion, the results indicate that multidetector CT pulmonary angiography and CT pulmonary angiography and CT venography may be used with various diagnostic strategies in adults of all ages and both genders...
  21. ncbi request reprint Pulmonary embolism and deep venous thrombosis in hospitalized adults with chronic obstructive pulmonary disease
    Paul D Stein
    St Joseph Mercy Oakland Hospital, Pontiac 48341 5023, and Wayne State University, Detroit, Michigan, USA
    J Cardiovasc Med (Hagerstown) 8:253-7. 2007
    ..We assessed the rate of diagnosis of PE and deep venous thrombosis (DVT) in hospitalized patients with COPD and the influence of age on relative risk compared with hospitalized patients who do not have COPD...
  22. doi request reprint 64-slice CT for diagnosis of coronary artery disease: a systematic review
    Paul D Stein
    St Joseph Mercy Oakland Hospital, Pontiac, MI 48341 5023, USA
    Am J Med 121:715-25. 2008
    ..The purpose of this systematic review was to assess the accuracy of 64-slice CT coronary angiography for the diagnosis of coronary artery disease...
  23. ncbi request reprint Outcome of pulmonary embolectomy
    Paul D Stein
    St Joseph Mercy Oakland Hospital, Pontiac, Michigan, USA
    Am J Cardiol 99:421-3. 2007
    ..In conclusion, despite generally high mortality in patients who undergo pulmonary embolectomy, it may have life-saving potential in some instances...
  24. ncbi request reprint Diagnostic pathways in acute pulmonary embolism: recommendations of the PIOPED II Investigators
    Paul D Stein
    Department of Research, St Joseph Mercy Oakland Hospital, 44405 Woodward Ave, Pontiac, MI 48341 5023, and Department of Medicine, Wayne State University, Detroit, MI, USA
    Radiology 242:15-21. 2007
  25. ncbi request reprint Diagnostic pathways in acute pulmonary embolism: recommendations of the PIOPED II investigators
    Paul D Stein
    Department of Research, St Joseph Mercy Oakland Hospital, Pontiac, Mich 48341 5023, USA
    Am J Med 119:1048-55. 2006
    ..To formulate comprehensive recommendations for the diagnostic approach to patients with suspected pulmonary embolism, based on randomized trials...
  26. ncbi request reprint Noninvasive imaging of the coronary arteries
    P D Stein
    St Joseph Mercy Oakland Hospital, 44405 Woodward Avenue, Pontiac, MI 48341 5023, USA
    Minerva Cardioangiol 54:619-31. 2006
    ..It was also shown to be useful for the detection of stenosis in coronary artery bypass grafts...
  27. ncbi request reprint Deep venous thrombosis and pulmonary embolism in hospitalized patients with sickle cell disease
    Paul D Stein
    St Joseph Mercy Oakland Hospital, Pontiac, Mich 48341 5023, USA
    Am J Med 119:897.e7-11. 2006
    ..The prevalence of deep venous thrombosis (DVT) is also undetermined in patients with SCD. Knowing the prevalence of DVT would be an important step in the overall assessment of the risk of PE in these patients...
  28. doi request reprint Reconstructed 4-chamber views compared with axial imaging for assessment of right ventricular enlargement on CT pulmonary angiograms
    Paul D Stein
    Department of Research, St Joseph Mercy Oakland Hospital, Pontiac, MI 48341 5023, USA
    J Thromb Thrombolysis 28:342-7. 2009
    ....
  29. pmc Methods of Prospective Investigation of Pulmonary Embolism Diagnosis III (PIOPED III)
    Paul D Stein
    Department of Research, St Joseph Mercy Oakland Hospital, Pontiac, MI 48341 5023, USA
    Semin Nucl Med 38:462-70. 2008
    ..This procedure will reduce the proportion of patients with negative tests at no loss in evaluation of sensitivity and specificity...
  30. doi request reprint Diabetes mellitus and risk of venous thromboembolism
    Paul D Stein
    Department of Research, St Joseph Mercy Oakland Hospital, Pontiac, Michigan, USA
    Am J Med Sci 337:259-64. 2009
    ..To determine if diabetes mellitus is a risk factor for venous thromboembolism (VTE)...
  31. doi request reprint Prognosis based on creatine kinase isoenzyme MB, cardiac troponin I, and right ventricular size in stable patients with acute pulmonary embolism
    Paul D Stein
    Department of Internal Medicine and Research and Advanced Studies Program, Michigan State University, East Lansing, MI, USA
    Am J Cardiol 107:774-7. 2011
    ..The combination of high CK-MB, high cTnI, and RV dilatation tended to indicate the highest mortality...
  32. doi request reprint Controversies in diagnosis of pulmonary embolism
    Paul D Stein
    Department of Internal Medicine and Research and Advanced Studies Program, Michigan State University College of Osteopathic Medicine, East Lansing, MI 48341, USA
    Clin Appl Thromb Hemost 17:140-9. 2011
    ..The choice depends on the patient's age, gender, and complexity of the findings on the plain chest radiograph...
  33. doi request reprint Epidemiology and incidence: the scope of the problem and risk factors for development of venous thromboembolism
    Paul D Stein
    Department of Internal Medicine and Research and Advanced Studies Program, College of Osteopathic Medicine, Michigan State University, MSU COM Venous Thromboembolism Research Unit, 44405 Woodward Avenue, Pontiac, MI 48341 5023, USA
    Clin Chest Med 31:611-28. 2010
    ..Epidemiologic data and new information on risk factors provide insight into making an informed clinical assessment and evaluation for antithrombotic prophylaxis...
  34. doi request reprint Modest response in translation to home management of deep venous thrombosis
    Paul D Stein
    Department of Internal Medicine and Research and Advanced Studies Program, Michigan State University College of Osteopathic Medicine, East Lansing, USA
    Am J Med 123:1107-13. 2010
    ..In the present study, we track the timelines of evidence for home treatment of deep venous thrombosis and its eventual impact on hospitalizations and early discharge...
  35. doi request reprint Is the campaign to prevent VTE in hospitalized patients working?
    Paul D Stein
    Department of Internal Medicine and the Research and Advanced Studies Program, Venous Thromboembolism Research Unit, Michigan State University College of Osteopathic Medicine, East Lansing, MI, USA
    Chest 139:1317-21. 2011
    ..Knowledge of such trends would be useful in assessing the effectiveness of antithrombotic prophylaxis in hospitalized patients who are at high risk...
  36. doi request reprint Outcome in stable patients with acute pulmonary embolism who had right ventricular enlargement and/or elevated levels of troponin I
    Paul D Stein
    Department of Internal Medicine and Research and Advanced Studies Program, Michigan State University, East Lansing, MI, USA
    Am J Cardiol 106:558-63. 2010
    ..The outcomes, however, were not extreme enough to warrant routine thrombolytic therapy...
  37. doi request reprint Resolution of pulmonary embolism on CT pulmonary angiography
    Paul D Stein
    Department of Internal Medicine, College of Osteopathic Medicine, Michigan State University, East Lansing, MI 44405 Woodward Ave, Pontiac, MI 48341 5023, USA
    AJR Am J Roentgenol 194:1263-8. 2010
    ..The objective of our study was to retrospectively determine the rate of resolution of pulmonary emboli (PEs) in individual vessels and the rate of complete resolution of PEs on CT angiography...
  38. doi request reprint Effect of compression stockings on venous blood velocity and blood flow
    P D Stein
    Department of Internal Medicine, College of Osteopathic Medicine, Michigan State University, East Lansing, Michigan, USA
    Thromb Haemost 103:138-44. 2010
    ..Thigh-length GCS did not increase popliteal vein blood velocity, diameter, or volumetric blood flow while supine or sitting, with or without ankle exercise...
  39. doi request reprint SPECT in acute pulmonary embolism
    Paul D Stein
    Department of Internal Medicine, College of Osteopathic Medicine, Michigan State University, East Lansing, Michigan 48341 5023, USA
    J Nucl Med 50:1999-2007. 2009
    ..Methods of obtaining SPECT images, methods of obtaining planar V/Q images, and the criteria for interpretation varied. The general impression is that SPECT is more advantageous than planar V/Q imaging...
  40. doi request reprint Early discharge of patients with venous thromboembolism: implications regarding therapy
    Paul D Stein
    Department of Internal Medicine, College of Osteopathic Medicine, Michigan State University, Venous Thromboembolism Research Unit St Joseph Mercy Oakland Hospital, 44405 Woodward Ave, Pontiac, MI 48341 5023, USA
    Clin Appl Thromb Hemost 16:141-5. 2010
    ..0 for 24 hours is recommended or extended outpatient treatment with LMWH may be considered...
  41. doi request reprint Obesity and thromboembolic disease
    Paul D Stein
    Department of Research, St Joseph Mercy Oakland Hospital, Pontiac, MI 48341 5023, USA
    Clin Chest Med 30:489-93, viii. 2009
    ..Obesity is also a risk factor for recurrent VTE. A synergistic effect of oral contraceptives with obesity has been shown...
  42. pmc Gadolinium-enhanced magnetic resonance angiography for pulmonary embolism: a multicenter prospective study (PIOPED III)
    Paul D Stein
    Michigan State University, College of Osteopathic Medicine, Department of Internal Medicine, Michigan State University Venous Thromboembolism Research Unit, St Joseph Mercy Oakland Hospital, 44405 Woodward Avenue, Pontiac, MI 48341 5023, USA
    Ann Intern Med 152:434-43, W142-3. 2010
    ..The accuracy of gadolinium-enhanced magnetic resonance pulmonary angiography and magnetic resonance venography for diagnosing pulmonary embolism has not been determined conclusively...
  43. doi request reprint CT venous phase venography with 64-detector CT angiography in the diagnosis of acute pulmonary embolism
    Paul D Stein
    Department of Research, St Joseph Mercy Oakland Hospital, Pontiac, Michigan, USA
    Clin Appl Thromb Hemost 16:422-9. 2010
    ..8%). In conclusion, the proportion of patients with venous thromboembolism diagnosed only by a CT venogram is sufficiently high to merit consideration of its use especially in those at high risk for DVT...
  44. ncbi request reprint Ankle exercise and venous blood velocity
    Paul D Stein
    Saint Joseph Mercy Oakland, 44405 Woodward Avenue, Pontiac, MI 48341 5023, USA
    Thromb Haemost 101:1100-3. 2009
    ..Such ankle exercise might be useful in the prevention of stasis-induced deep venous thrombosis...
  45. doi request reprint Incidence of thrombocytopenia in hospitalized patients with venous thromboembolism
    Paul D Stein
    Research and Advanced Studies Program, Michigan State University, College of Osteopathic Medicine, Detroit Medical Center Campus, Detroit, MI, USA
    Am J Med 122:919-30. 2009
    ..To determine the incidence of heparin-associated thrombocytopenia in patients receiving prophylaxis or treatment for venous thromboembolism...
  46. ncbi request reprint Antithrombotic therapy in patients with mechanical and biological prosthetic heart valves
    P D Stein
    St Joseph Mercy Oakland Hospital, Pointia, MI 48341 2964, USA
    Chest 119:220S-227S. 2001
    ..5 to 4.0 and were associated with fewer bleeding complications during the first 3 months after operation.10. Aspirin may reduce the long-term frequency of thromboembolism in patients with bioprosthetic valves...
  47. ncbi request reprint Trends in the use of diagnostic imaging in patients hospitalized with acute pulmonary embolism
    Paul D Stein
    St Joseph Mercy Oakland Hospital, 44555 Woodward Avenue, Suirte 107, Pontiac, MI 48341 2985, USA
    Am J Cardiol 93:1316-7. 2004
    ..By 2001, there was a higher proportion of imaging tests with CT than VQ scans (36% vs 32%). Even so, in the United States, a large proportion of patients continued to have VQ scans...
  48. ncbi request reprint Venous thromboembolism in pregnancy: 21-year trends
    Paul D Stein
    University of Calgary, Alberta, Canada, USA
    Am J Med 117:121-5. 2004
  49. ncbi request reprint Twenty-one-year trends in the use of inferior vena cava filters
    Paul D Stein
    Department of Research, St Joseph Mercy Oakland Hospital, Pontiac, MI 48341 2985, USA
    Arch Intern Med 164:1541-5. 2004
    ..We analyzed the National Hospital Discharge Survey (NHDS) database for such trends...
  50. ncbi request reprint D-dimer for the exclusion of acute venous thrombosis and pulmonary embolism: a systematic review
    Paul D Stein
    Saint Joseph Mercy Oakland, Pontiac, Michigan 48341, USA
    Ann Intern Med 140:589-602. 2004
    ..Despite extensive literature, the diagnostic role of d-dimer for deep venous thrombosis (DVT) or pulmonary embolism (PE) remains unclear, reflecting multiple d-dimer assays and concerns about differing sensitivities and variability...
  51. ncbi request reprint Antithrombotic therapy in patients with saphenous vein and internal mammary artery bypass grafts: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy
    Paul D Stein
    St Joseph Mercy Oakland, 44555 Woodward Ave, Suite 107, Pontiac, MI 48341, USA
    Chest 126:600S-608S. 2004
    ..For all patients undergoing IMA bypass grafting without other indication for VKA, we suggest clinicians not use VKA (Grade 2C)...
  52. ncbi request reprint Outcome and complications of retrievable inferior vena cava filters
    Paul D Stein
    St Joseph Mercy Oakland Hospital, Pontiac, Michigan 48341 3244, USA
    Am J Cardiol 94:1090-3. 2004
    ..Surgery was necessary to remove the filter from 1 patient (1%), and filters could not be removed because of large trapped thrombi in 14 patients (9%)...
  53. ncbi request reprint Incidence of venous thromboembolism in infants and children: data from the National Hospital Discharge Survey
    Paul D Stein
    Department of Research, St Joseph Mercy Oakland Hospital, Pontiac, MI 48341 2985, USA
    J Pediatr 145:563-5. 2004
    ..They were more frequent in infants 0 to 1 year of age and in teenagers 15 to 17 years of age than in children 2 to 14 years of age. Pregnancies doubled the rate of DVT in teenage girls...
  54. ncbi request reprint Venous thromboembolism according to age: the impact of an aging population
    Paul D Stein
    Department of Research, St Joseph Mercy Oakland Hospital, Pontiac, Mich 48341 3244, USA
    Arch Intern Med 164:2260-5. 2004
    ..In this study we sought to determine trends in the diagnosis of deep venous thrombosis (DVT) and pulmonary embolism (PE) in the elderly as well as the use of diagnostic tests...
  55. ncbi request reprint Estimated case fatality rate of pulmonary embolism, 1979 to 1998
    Paul D Stein
    St Joseph Mercy Oakland Hospital, Pontiac, Michigan, USA
    Am J Cardiol 93:1197-9. 2004
    ....
  56. ncbi request reprint Regional differences in rates of diagnosis and mortality of pulmonary thromboembolism
    Paul D Stein
    St Joseph Mercy Oakland Hospital, Pontiac, Pontiac, Michigan, USA
    Am J Cardiol 93:1194-7. 2004
    ..The western region of the United States showed a lower rate of diagnosis of deep venous thrombosis and venous thromboembolism and a lower mortality rate of PE than any other region...
  57. ncbi request reprint Estimated incidence of acute pulmonary embolism in a community/teaching general hospital
    Paul D Stein
    St Joseph Mercy Oakland, Pontiac, MI 48341 2985, USA
    Chest 121:802-5. 2002
    ..This study attempts to determine the incidence of established acute pulmonary embolism (PE) in a community/teaching general hospital...
  58. ncbi request reprint Deep venous thrombosis in a general hospital
    Paul D Stein
    St Joseph Mercy Oakland Hospital, Pontiac, MI 48341, USA
    Chest 122:960-2. 2002
    ..To determine the prevalence of proximal deep venous thrombosis (DVT) in a general hospital...
  59. ncbi request reprint Tracking the uptake of evidence: two decades of hospital practice trends for diagnosing deep vein thrombosis and pulmonary embolism
    Paul D Stein
    St Joseph Mercy Oakland Hospital, 44555 Woodward Avenue, Suite 107, Pontiac, MI 48341 2985, USA
    Arch Intern Med 163:1213-9. 2003
    ..To assess whether these advances correlate with clinical practice, we analyzed 21-year trends in diagnostic testing for patients with venous thromboembolism...
  60. ncbi request reprint Venous thromboembolic disease: comparison of the diagnostic process in men and women
    Paul D Stein
    Department of Research, St Joseph Mercy Oakland Hospital, Pontiac, Michigan, USA
    Arch Intern Med 163:1689-94. 2003
    ..There has been concern that women may be limited to fewer major diagnostic tests than men. Whether this applies to patients with pulmonary embolism (PE) or deep venous thrombosis (DVT) has not been determined...
  61. ncbi request reprint Venous thromboembolic disease: comparison of the diagnostic process in blacks and whites
    Paul D Stein
    Research Department, St Joseph Mercy Oakland Hospital, Pontiac, MI 48341 2985, USA
    Arch Intern Med 163:1843-8. 2003
    ..There has been concern that a disproportionate use of some health services exists among races. Whether this applies to patients with pulmonary embolism (PE) or deep venous thrombosis (DVT) has not been determined...
  62. ncbi request reprint Gadolinium-enhanced magnetic resonance angiography for detection of acute pulmonary embolism: an in-depth review
    Paul D Stein
    St Joseph Mercy Oakland Hospital, 44555 Woodward Avenue, Suite 107, Pontiac, MI 48341 2985, USA
    Chest 124:2324-8. 2003
    ....
  63. ncbi request reprint Analysis of occurrence of venous thromboembolic disease in the four seasons
    Paul D Stein
    St Joseph Mercy Oakland Hospital, Pontiac, Michigan 48341 2985, USA
    Am J Cardiol 93:511-3. 2004
    ....
  64. ncbi request reprint Pulmonary thromboembolism in Asians/Pacific Islanders in the United States: analysis of data from the National Hospital Discharge Survey and the United States Bureau of the Census
    Paul D Stein
    Saint Joseph Mercy Oakland Hospital, Pontiac, Michigan 48341 2985, USA
    Am J Med 116:435-42. 2004
    ..To assess the rate of diagnosis of deep venous thrombosis, pulmonary embolism, and venous thromboembolism; the incidence in hospitalized patients; and mortality from pulmonary embolism among Asians/Pacific Islanders in the United States...
  65. ncbi request reprint Trends in the incidence of pulmonary embolism and deep venous thrombosis in hospitalized patients
    Paul D Stein
    St Joseph Mercy Oakland Hospital, Pontiac, Michigan 48341 5023, USA
    Am J Cardiol 95:1525-6. 2005
    ..8% of admissions to 1.3% of admissions. The incidence of PE was 0.4% of admissions and did not change over the 21-year period. Trends and incidences were similar or the same among men and women and whites and blacks...
  66. ncbi request reprint Mortality from acute pulmonary embolism according to season
    Paul D Stein
    St Joseph Mercy Oakland Hospital, Pontiac, MI 48341 2985, USA
    Chest 128:3156-8. 2005
    ..Varying observations have been made on seasonal differences of mortality from acute pulmonary embolism (PE)...
  67. ncbi request reprint Pulmonary thromboembolism in American Indians and Alaskan Natives
    Paul D Stein
    Department of Research, St Joseph Mercy Oakland Hospital, Pontiac, MI 48341 2985, USA
    Arch Intern Med 164:1804-6. 2004
    ..Expansion of the national census in 1990 to include American Indians and Alaskan Natives permits a more in-depth examination of this issue...
  68. ncbi request reprint Pulmonary embolism as a cause of death in patients who died with cancer
    Paul D Stein
    St Joseph Mercy Oakland Hospital, Pontiac, Mich 48341 5023, USA
    Am J Med 119:163-5. 2006
    ..In conclusion, with modern diagnostic, prophylactic, and therapeutic methods, death from pulmonary embolism in patients who died with cancer was 1% or less...
  69. ncbi request reprint Incidence of venous thromboembolism in patients hospitalized with cancer
    Paul D Stein
    St Joseph Mercy Oakland Hospital, Pontiac, Mich 48341 5023, USA
    Am J Med 119:60-8. 2006
    ..We sought to determine the incidence and relative risk of venous thromboembolism, pulmonary embolism, and deep venous thrombosis in patients with malignancies...
  70. ncbi request reprint Obesity as a risk factor in venous thromboembolism
    Paul D Stein
    St Joseph Mercy Oakland Hospital, Pontiac, MI 48341, USA
    Am J Med 118:978-80. 2005
    ..Whether obesity is an independent risk factor for pulmonary embolism or deep venous thrombosis has not been fully determined...
  71. ncbi request reprint Multidetector computed tomography for the diagnosis of coronary artery disease: a systematic review
    Paul D Stein
    Department of Research, St Joseph Mercy Oakland Hospital, Pontiac, Mich 48341 2985, USA
    Am J Med 119:203-16. 2006
    ..The study's purpose was to determine the sensitivity and specificity of contrast-enhanced multidetector computed tomography (CT) for the detection of coronary artery disease...
  72. ncbi request reprint Multidetector computed tomography for acute pulmonary embolism
    Paul D Stein
    Department of Research, St Joseph Mercy Oakland Hospital, Pontiac, Mich, USA
    N Engl J Med 354:2317-27. 2006
    ..The accuracy of multidetector computed tomographic angiography (CTA) for the diagnosis of acute pulmonary embolism has not been determined conclusively...
  73. ncbi request reprint Spiral computed tomography for the diagnosis of acute pulmonary embolism
    Paul D Stein
    St Joseph Mercy Oakland Hospital, Pontiac, Michigan 48341 5023, USA
    Thromb Haemost 98:713-20. 2007
    ..Outcome studies showed recurrent PE in only 1.7% or fewer untreated patients with negative CT pulmonary angiograms...
  74. ncbi request reprint Usefulness of 4-, 8-, and 16-slice computed tomography for detection of graft occlusion or patency after coronary artery bypass grafting
    Paul D Stein
    Department of Research, St Joseph Mercy Oakland Hospital, Pontiac, Michigan, USA
    Am J Cardiol 96:1669-73. 2005
    ..The data suggest that 4- and 16-slice CT can be used for the detection of complete graft occlusion or graft patency of CABGs. Significant stenosis was better assessed with 16-slice CT than with 4-slice CT...
  75. doi request reprint Increasing use of vena cava filters for prevention of pulmonary embolism
    Paul D Stein
    Department of Internal Medicine and Research and Advanced Studies Program, College of Osteopathic Medicine, Michigan State University, East Lansing, USA
    Am J Med 124:655-61. 2011
    ..To test whether the use of vena cava filters continues to increase in the era of retrievable filters, suggesting that indications for insertion are broadening...
  76. ncbi request reprint Treatment of acute pulmonary embolism as outpatients or following early discharge. A systematic review
    Muhammad Janjua
    William Beaumont Hospital, Royal Oak, MI, USA
    Thromb Haemost 100:756-61. 2008
    ..In conclusion, outpatient therapy of acute PE is probably safe in low-risk, carefully selected compliant patients who have access to outpatient care if necessary. Such outpatient treatment would be cost-effective...
  77. ncbi request reprint Risk of venous thromboembolism with rheumatoid arthritis
    Fadi Matta
    Saint Joseph Mercy Oakland, 44405 Woodward Avenue, Pontiac, MI 48341 5023, USA
    Thromb Haemost 101:134-8. 2009
    ..A heightened awareness of the risks for VTE and a lower threshold for evaluation of patients for possible DVT or PE would be appropriate in caring for hospitalized patients with rheumatoid arthritis...
  78. ncbi request reprint Antithrombotic therapy in patients with mechanical and biological prosthetic heart valves
    P D Stein
    Henry Ford Hospital Cardiac Wellness Center, Detroit, MI 48202, USA
    Chest 114:602S-610S. 1998
    ..0 to 2.3 were as effective as at an INR of 2.5 to 4.5: additionally, fewer bleeding complications were seen...
  79. ncbi request reprint Antithrombotic therapy in valvular heart disease
    P D Stein
    St Joseph Mercy Oakland Hospital, Pontiac, Michigan, USA
    Clin Geriatr Med 17:163-72, viii. 2001
    ....
  80. ncbi request reprint Upper extremity deep venous thrombosis
    Syed Mustafa
    St Joseph Mercy Oakland, Pontiac, MI 48341, USA
    Chest 123:1953-6. 2003
    ..To determine the prevalence of symptomatic upper extremity deep venous thrombosis (DVT) and its association with symptomatic acute pulmonary embolism (PE) in a community teaching hospital...
  81. ncbi request reprint Very low probability interpretation of V/Q lung scans in combination with low probability objective clinical assessment reliably excludes pulmonary embolism: data from PIOPED II
    Alexander Gottschalk
    Department of Radiology, Michigan State University, East Lansing, MI 48824, USA
    J Nucl Med 48:1411-5. 2007
    ..The purpose of this investigation was to test the hypothesis that a very low probability interpretation of the V/Q scan has a PPV of <10%...
  82. doi request reprint Silent pulmonary embolism in patients with deep venous thrombosis: a systematic review
    Paul D Stein
    Departments of Internal Medicine, College of Osteopathic Medicine, Michigan State University, East Lansing, MI, USA
    Am J Med 123:426-31. 2010
    ..To determine, by systematic review of the literature, the prevalence of silent pulmonary embolism in patients with deep venous thrombosis...
  83. doi request reprint Anticoagulant therapy for acute venous thromboembolism: what we think we know and what the data show for the timing of recurrent events
    Paul D Stein
    Department of Internal Medicine, College of Osteopathic Medicine, Michigan State University, St Joseph Mercy Oakland Hospital, East Lansing, Michigan 48341, USA
    Clin Appl Thromb Hemost 15:609-12. 2009
    ..Later recurrences are the norm and may be reduced by early treatment with adequate heparin...
  84. ncbi request reprint Multidetector computed tomography for the diagnosis of acute pulmonary embolism
    Paul D Stein
    St Joseph Mercy Oakland Hospital, Pontiac, Michigan 48341 5023, USA
    Curr Opin Pulm Med 13:384-8. 2007
    ....
  85. ncbi request reprint Antithrombotic therapy in patients with saphenous vein and internal mammary artery bypass grafts
    P D Stein
    Henry Ford Health System, Cardiac Wellness Center, Detroit, MI 48202 3006, USA
    Chest 114:658S-665S. 1998
    ..Antithrombotic agents given to patients with internal mammary artery bypass grafts showed no benefit in comparison to placebo because patency on placebo was high...
  86. ncbi request reprint Preoperative vs postoperative initiation of low-molecular-weight heparin prophylaxis against venous thromboembolism in patients undergoing elective hip replacement
    R D Hull
    Thrombosis Research Unit, Foothills Hospital, University of Calgary, Alberta, Canada
    Arch Intern Med 159:137-41. 1999
    ..In the absence of a published definitive level 1 trial addressing this question, a meta-analysis is appropriate...
  87. ncbi request reprint Timing of initial administration of low-molecular-weight heparin prophylaxis against deep vein thrombosis in patients following elective hip arthroplasty: a systematic review
    R D Hull
    Thrombosis Research Unit, University of Calgary, Alberta, Canada
    Arch Intern Med 161:1952-60. 2001
    ..We performed a systematic review of the literature to assess the efficacy and safety of low-molecular-weight heparin administered at different times in relation to surgery vs oral anticoagulant prophylaxis...
  88. ncbi request reprint Low-molecular-weight heparin vs heparin in the treatment of patients with pulmonary embolism. American-Canadian Thrombosis Study Group
    R D Hull
    Department of Community Health Sciences, University of Calgary, Alberta, Canada
    Arch Intern Med 160:229-36. 2000
    ..Recent rigorous clinical trials have established objective criteria for determining a high probability of PE by perfusion lung scanning...
  89. ncbi request reprint Extended out-of-hospital low-molecular-weight heparin prophylaxis against deep venous thrombosis in patients after elective hip arthroplasty: a systematic review
    R D Hull
    Thrombosis Research Unit, University of Calgary, Foothills Hospital, Room 601 South Tower, 1403 29th Street NW, Calgary, T2N 2T9 Alberta, Canada
    Ann Intern Med 135:858-69. 2001
    ..To provide clinicians with a practical pathway for translating clinical research into practice, we systematically reviewed trials comparing extended out-of-hospital LMWH prophylaxis versus placebo...
  90. ncbi request reprint Incidence of pregnancy-associated venous thromboembolism
    Paul D Stein
    Ann Intern Med 144:453-4; author reply 454-5. 2006
  91. doi request reprint Acute pulmonary embolism: sensitivity and specificity of ventilation-perfusion scintigraphy in PIOPED II study
    H Dirk Sostman
    Weill Cornell Medical College and the Methodist Hospital, 6565 Fannin St, Houston, TX 77030, USA
    Radiology 246:941-6. 2008
    ....
  92. ncbi request reprint Catheter-directed thrombolysis (intrathrombus injection) in treatment of deep venous thrombosis: a systematic review
    Issa Alesh
    Department of Research, St Joseph Mercy Oakland Hospital, Pontiac, Michigan, USA
    Catheter Cardiovasc Interv 70:143-8. 2007
    ..An advantage is that it lends itself to adjunct treatment following the administration of thrombolytic agents if the thrombolysis is inadequate...
  93. ncbi request reprint Fatal vascular outcomes following major orthopedic surgery
    Ola E Dahl
    Thrombosis Research Institute, London, UK
    Thromb Haemost 93:860-6. 2005
    ..In conclusion, although prophylaxis results in a reduction in overall mortality and fatal pulmonary embolism, vascular events continue to be a common cause of mortality...
  94. ncbi request reprint CT venography and compression sonography are diagnostically equivalent: data from PIOPED II
    Lawrence R Goodman
    Department of Diagnostic Radiology, Medical College of Wisconsin, 9200 W Wisconsin Ave, Milwaukee, WI 53226 3596, USA
    AJR Am J Roentgenol 189:1071-6. 2007
    ..The Prospective Investigation of Pulmonary Embolism Diagnosis II (PIOPED II) showed that lower extremity imaging detects about 7% more patients requiring anticoagulation than CTA alone...
  95. doi request reprint Venous thromboembolism in patients hospitalized with nephrotic syndrome
    Fadi Kayali
    St Joseph Mercy Oakland Hospital, Pontiac, MI 48341 5023, USA
    Am J Med 121:226-30. 2008
    ..To determine which is the likely cause of pulmonary embolism in patients with the nephrotic syndrome, we investigated data from the National Hospital Discharge Survey...
  96. ncbi request reprint Antithrombotic therapy in valvular heart disease--native and prosthetic: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy
    Deeb N Salem
    Tufts New England Medical Center, 750 Washington St, Boston, MA 02111, USA
    Chest 126:457S-482S. 2004
    ..For patients with bioprosthetic valves who are in sinus rhythm and do not have AF, we recommend long-term (> 3 months) therapy with aspirin, 75 to 100 mg/d (Grade 1C+)...
  97. ncbi request reprint Catheter-tip embolectomy in the management of acute massive pulmonary embolism
    Elias Skaf
    Department of Research, St Joseph Mercy Oakland Hospital, Pontiac, Michigan, USA
    Am J Cardiol 99:415-20. 2007
    ..None reported perforation of a pulmonary artery. In conclusion, all the devices analyzed in this study appear to be useful in the management of acute massive pulmonary emboli...
  98. ncbi request reprint Risk of venous thromboembolism in patients hospitalized with heart failure
    Afzal Beemath
    St Joseph Mercy Oakland Hospital, Pontiac, Michigan
    Am J Cardiol 98:793-5. 2006
    ..72), and the relative risk for DVT was 5.46. In conclusion, a high relative risk for PE, DVT, and venous thromboembolism was shown in patients with CHF who were <60 years of age...
  99. ncbi request reprint CT venography for deep venous thrombosis: continuous images versus reformatted discontinuous images using PIOPED II data
    Lawrence R Goodman
    Department of Radiology, Medical College of Wisconsin, 9200 W Wisconsin Ave, Milwaukee, WI 53226 3596, USA
    AJR Am J Roentgenol 189:409-12. 2007
    ....
  100. ncbi request reprint Diagnostic algorithms for deep vein thrombosis: work in progress
    Russell D Hull
    Am J Med 113:687-8. 2002
  101. ncbi request reprint Thromboembolic disease involving the superior vena cava and brachiocephalic veins
    Todd R Otten
    St Joseph Mercy Oakland, Pontiac, MI 48341, USA
    Chest 123:809-12. 2003
    ..To evaluate the frequency of diagnosis and the characteristics of brachiocephalic vein and superior vena cava (SVC) thromboembolic disease...

Research Grants3

  1. PROSPECTIVE INVESTIGATION OF PULMONARY EMBOLISM DX-II
    Paul Stein; Fiscal Year: 2003
    ..4) The team of investigators is strong, and has collaborated previously in successful research in PE. ..
  2. Prospective Investigation for Pulmonary Embolism Dx III
    Paul Stein; Fiscal Year: 2007
    ..abstract_text> ..