Carlos Rodriguez-Galindo

Summary

Affiliation: St. Jude Children's Research Hospital
Country: USA

Publications

  1. ncbi request reprint Treatment of retinoblastoma: current status and future perspectives
    Carlos Rodriguez-Galindo
    Carlos Rodriguez Galindo, MD Department of Oncology, St Jude Children s Research Hospital, 332 N Lauderdale, Memphis, TN 38105, USA
    Curr Treat Options Neurol 9:294-307. 2007
  2. ncbi request reprint Treatment of metastatic retinoblastoma
    Carlos Rodriguez-Galindo
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Ophthalmology 110:1237-40. 2003
  3. ncbi request reprint Outcome after local recurrence of osteosarcoma: the St. Jude Children's Research Hospital experience (1970-2000)
    Carlos Rodriguez-Galindo
    Department of Hematology Oncology, St Jude Children s Research Hospital, and Department of Pediatrics, University of Tennessee, Memphis, USA
    Cancer 100:1928-35. 2004
  4. ncbi request reprint Pharmacological management of Ewing sarcoma family of tumours
    Carlos Rodriguez-Galindo
    St Jude Children s Research Hospital, Department of Hematology Oncology, 332 N Lauderdale, Memphis, TN 38105, USA
    Expert Opin Pharmacother 5:1257-70. 2004
  5. pmc Retinoblastoma: one world, one vision
    Carlos Rodriguez-Galindo
    Department of Oncology, St Jude Children s Research Hospital, 332 N Lauderdale, Memphis, TN 38105, USA
    Pediatrics 122:e763-70. 2008
  6. ncbi request reprint Preradiation chemotherapy with methotrexate, cisplatin, 5-fluorouracil, and leucovorin for pediatric nasopharyngeal carcinoma
    Carlos Rodriguez-Galindo
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Cancer 103:850-7. 2005
  7. doi request reprint Clofarabine in refractory Langerhans cell histiocytosis
    Carlos Rodriguez-Galindo
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Pediatr Blood Cancer 51:703-6. 2008
  8. ncbi request reprint Biology, clinical characteristics, and management of adrenocortical tumors in children
    Carlos Rodriguez-Galindo
    Department of Hematology Oncology, St Jude Children s Research Hospital, 332 N Lauderdale, Memphis, TN 38105 2794, USA
    Pediatr Blood Cancer 45:265-73. 2005
  9. ncbi request reprint Phase I study of the combination of topotecan and irinotecan in children with refractory solid tumors
    Carlos Rodriguez-Galindo
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2795, USA
    Cancer Chemother Pharmacol 57:15-24. 2006
  10. ncbi request reprint Prognostic factors for local and distant control in Ewing sarcoma family of tumors
    C Rodriguez-Galindo
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Ann Oncol 19:814-20. 2008

Detail Information

Publications91

  1. ncbi request reprint Treatment of retinoblastoma: current status and future perspectives
    Carlos Rodriguez-Galindo
    Carlos Rodriguez Galindo, MD Department of Oncology, St Jude Children s Research Hospital, 332 N Lauderdale, Memphis, TN 38105, USA
    Curr Treat Options Neurol 9:294-307. 2007
    ....
  2. ncbi request reprint Treatment of metastatic retinoblastoma
    Carlos Rodriguez-Galindo
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Ophthalmology 110:1237-40. 2003
    ..The risk for death in patients with retinoblastoma is increased in those who present with metastatic disease, and the role of intensive chemotherapy and autologous hematopoietic stem cell rescue in these patients remains unclear...
  3. ncbi request reprint Outcome after local recurrence of osteosarcoma: the St. Jude Children's Research Hospital experience (1970-2000)
    Carlos Rodriguez-Galindo
    Department of Hematology Oncology, St Jude Children s Research Hospital, and Department of Pediatrics, University of Tennessee, Memphis, USA
    Cancer 100:1928-35. 2004
    ..Despite improvements in therapy for osteosarcoma, approximately 4-10% of patients experience a local recurrence and have a poor prognosis...
  4. ncbi request reprint Pharmacological management of Ewing sarcoma family of tumours
    Carlos Rodriguez-Galindo
    St Jude Children s Research Hospital, Department of Hematology Oncology, 332 N Lauderdale, Memphis, TN 38105, USA
    Expert Opin Pharmacother 5:1257-70. 2004
    ..The benefit of this approach is unclear and HSCT must therefore be considered investigational. New strategies, such as the use of immunotherapy, biological modifiers and novel classes of chemotherapeutic agents must be explored...
  5. pmc Retinoblastoma: one world, one vision
    Carlos Rodriguez-Galindo
    Department of Oncology, St Jude Children s Research Hospital, 332 N Lauderdale, Memphis, TN 38105, USA
    Pediatrics 122:e763-70. 2008
    ....
  6. ncbi request reprint Preradiation chemotherapy with methotrexate, cisplatin, 5-fluorouracil, and leucovorin for pediatric nasopharyngeal carcinoma
    Carlos Rodriguez-Galindo
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Cancer 103:850-7. 2005
    ..Chemotherapy may help to decrease the radiotherapy dose and limit the side effects of local therapies. However, little is known regarding the chemosensitivity of NPC tumors in pediatric patients...
  7. doi request reprint Clofarabine in refractory Langerhans cell histiocytosis
    Carlos Rodriguez-Galindo
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Pediatr Blood Cancer 51:703-6. 2008
    ..In this report we describe significant single agent activity of clofarabine in disseminated LCH refractory to salvage regimens, including cladribine...
  8. ncbi request reprint Biology, clinical characteristics, and management of adrenocortical tumors in children
    Carlos Rodriguez-Galindo
    Department of Hematology Oncology, St Jude Children s Research Hospital, 332 N Lauderdale, Memphis, TN 38105 2794, USA
    Pediatr Blood Cancer 45:265-73. 2005
    ..Multi-institutional and prospective studies are necessary to further our understanding of the pathogenesis and to improve outcomes...
  9. ncbi request reprint Phase I study of the combination of topotecan and irinotecan in children with refractory solid tumors
    Carlos Rodriguez-Galindo
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2795, USA
    Cancer Chemother Pharmacol 57:15-24. 2006
    ..Combining both agents may increase the amount of camptothecin delivered to the tumor, without additive toxicity...
  10. ncbi request reprint Prognostic factors for local and distant control in Ewing sarcoma family of tumors
    C Rodriguez-Galindo
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Ann Oncol 19:814-20. 2008
    ..The individual contributions of each treatment component cannot be analyzed separately; improvements in local and systemic control can influence each other...
  11. ncbi request reprint Treatment of intraocular retinoblastoma with vincristine and carboplatin
    Carlos Rodriguez-Galindo
    Department of Hematology Oncology, St Jude Children s Research Hospital, 332 North Lauderdale, Memphis, TN 38105, USA
    J Clin Oncol 21:2019-25. 2003
    ..To evaluate the efficacy of chemoreduction using vincristine and carboplatin in preventing or delaying external-beam radiotherapy (EBRT) or enucleation in patients with intraocular retinoblastoma...
  12. ncbi request reprint Treatment of children with Langerhans cell histiocytosis with 2-chlorodeoxyadenosine
    Carlos Rodriguez-Galindo
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Am J Hematol 69:179-84. 2002
    ..2-CdA needs to be considered for the treatment of recurrent LCH. However, its incorporation into front-line treatment of patients with multi-system LCH needs further study...
  13. ncbi request reprint Survival after recurrence of Ewing tumors: the St Jude Children's Research Hospital experience, 1979-1999
    Carlos Rodriguez-Galindo
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Cancer 94:561-9. 2002
    ..Despite improved therapies, 30-40% of patients with Ewing tumors (ET) experience recurrence and have a poor prognosis. The authors analyzed factors prognostic of survival in patients with recurrent ET...
  14. ncbi request reprint Clinical use of topoisomerase I inhibitors in anticancer treatment
    C Rodriguez-Galindo
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Med Pediatr Oncol 35:385-402. 2000
    ..These studies have shown promising results, and have placed topotecan and irinotecan in the first line treatment for some malignancies. However, studies to better determine the optimal schedules and sequence of combinations are needed...
  15. ncbi request reprint Neonatal alveolar rhabdomyosarcoma with skin and brain metastases
    C Rodriguez-Galindo
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Cancer 92:1613-20. 2001
    ..However, because RMS rarely occurs during the neonatal period, little is known about neonatal RMS...
  16. ncbi request reprint Treatment of Ewing sarcoma family of tumors: current status and outlook for the future
    Carlos Rodriguez-Galindo
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Med Pediatr Oncol 40:276-87. 2003
    ..Our current understanding in the biology and treatment of ESFT suggests that a more rational approach to the development of risk-adapted therapy should be undertaken...
  17. ncbi request reprint Treatment of refractory osteosarcoma with fractionated cyclophosphamide and etoposide
    Carlos Rodriguez-Galindo
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    J Pediatr Hematol Oncol 24:250-5. 2002
    ..By identifying new chemotherapeutic strategies, the outcome of these patients can be improved and the toxicity of treatment regimens decreased...
  18. ncbi request reprint Definitive irradiation in multidisciplinary management of localized Ewing sarcoma family of tumors in pediatric patients: outcome and prognostic factors
    Matthew J Krasin
    Department of Radiological Sciences, Division of Radiation Oncology, St Jude Children s Research Hospital, 332 North Lauderdale, Memphis, TN 38105 2794, USA
    Int J Radiat Oncol Biol Phys 60:830-8. 2004
    ..To assess the effect of radiation dose on local tumor control of the Ewing sarcoma family of tumors in 79 patients with localized disease treated at a single institution...
  19. ncbi request reprint Definitive surgery and multiagent systemic therapy for patients with localized Ewing sarcoma family of tumors: local outcome and prognostic factors
    Matthew J Krasin
    Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Cancer 104:367-73. 2005
    ....
  20. ncbi request reprint Metastatic osteosarcoma
    Najat C Daw
    Department of Hematology Oncology, St Jude Children s Research Hospital, University of Tennessee Health Science Center, Memphis, Tennessee 38105 2794, USA
    Cancer 106:403-12. 2006
    ..The initial study (OS-86) used ifosfamide, cisplatin, doxorubicin, and high-dose methotrexate, and the subsequent study (OS-91) used the same agents at similar doses, but carboplatin was substituted for cisplatin...
  21. pmc Topotecan and vincristine combination is effective against advanced bilateral intraocular retinoblastoma and has manageable toxicity
    Ibrahim Qaddoumi
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Cancer 118:5663-70. 2012
    ..New, effective chemotherapeutic agents are needed for intraocular retinoblastoma...
  22. pmc Carboplatin-associated ototoxicity in children with retinoblastoma
    Ibrahim Qaddoumi
    St Jude Children s Research Hospital, Memphis, TN 38105 3678, USA
    J Clin Oncol 30:1034-41. 2012
    ..We retrospectively assessed the incidence of ototoxicity and its risk factors in children with retinoblastoma who were treated with carboplatin...
  23. ncbi request reprint World disparities in risk definition and management of retinoblastoma: a report from the International Retinoblastoma Staging Working Group
    Guillermo L Chantada
    Hospital JP Garrahan, Buenos Aires, Argentina and International Outreach Program, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Pediatr Blood Cancer 50:692-4. 2008
    ..Internet meetings are a valuable mechanism for enabling participation from under-resourced countries in the development of cooperative studies...
  24. ncbi request reprint Socioeconomic impact of modern multidisciplinary management of retinoblastoma
    Matthew W Wilson
    Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    Pediatrics 118:e331-6. 2006
    ..Our objective for this study was to examine the impact of the modern management of intraocular retinoblastoma on the patient and the family...
  25. ncbi request reprint High-dose methotrexate pharmacokinetics and outcome of children and young adults with osteosarcoma
    Kristine R Crews
    Department of Pharmaceutical Sciences, St Judes Children s Research Hospital, Memphis, Tennessee 38105, USA
    Cancer 100:1724-33. 2004
    ..The authors evaluated the impact of factors such as age and prior nephrotoxic agents on MTX pharmacokinetics in children and young adults with osteosarcoma and examined whether MTX pharmacokinetic parameters were associated with outcome...
  26. pmc Tyrosine kinase inhibitor enhances the bioavailability of oral irinotecan in pediatric patients with refractory solid tumors
    Wayne L Furman
    Department of Oncology, St Jude Children s Research Hospital, 262 Danny Thomas Pl, Memphis, TN 38105 3678, USA
    J Clin Oncol 27:4599-604. 2009
    ..To assess the effect of gefitinib on the pharmacokinetics of IV irinotecan and on the bioavailability of a single oral dose of irinotecan...
  27. ncbi request reprint Effect on ocular survival of adding early intensive focal treatments to a two-drug chemotherapy regimen in patients with retinoblastoma
    Matthew W Wilson
    Department of Ophthalmology, University of Tennessee Health Science Center, 930 Madison Avenue, Memphis, TN 38163, USA
    Am J Ophthalmol 140:397-406. 2005
    ..To evaluate vincristine and carboplatin with intensive focal treatments in the management of intraocular retinoblastoma...
  28. ncbi request reprint Clinical field testing of an enhanced-activity intervention in hospitalized children with cancer
    Pamela S Hinds
    Division of Nursing Research, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    J Pain Symptom Manage 33:686-97. 2007
    ..Our findings identify design and statistical considerations for a future effectiveness study of the EPA intervention in hospitalized pediatric oncology patients...
  29. pmc Preliminary results from a prospective study using limited margin radiotherapy in pediatric and young adult patients with high-grade nonrhabdomyosarcoma soft-tissue sarcoma
    Matthew J Krasin
    Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Int J Radiat Oncol Biol Phys 76:874-8. 2010
    ..To demonstrate the safety and efficacy of limited margin radiotherapy in the local control of pediatric and young adult patients with high-grade nonrhabdomyosarcoma soft tissue sarcoma (NRSTS)...
  30. ncbi request reprint Ocular preservation after 36 Gy external beam radiation therapy for retinoblastoma
    Thomas E Merchant
    Department of Radiation Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    J Pediatr Hematol Oncol 24:246-9. 2002
    ..The purpose of this study was to document the ocular preservation rate after 36 Gy external beam radiation therapy (EBRT) for retinoblastoma...
  31. doi request reprint Pediatric anophthalmic sockets and orbital implants: outcomes with polymer-coated implants
    Maria Kirzhner
    Department of Ophthalmology, Hamilton Eye Institute, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    Ophthalmology 120:1300-4. 2013
    ..To compare wrapped and polymer-coated hydroxyapatite implants in children undergoing primary enucleation with no adjuvant therapies...
  32. ncbi request reprint Cefixime allows greater dose escalation of oral irinotecan: a phase I study in pediatric patients with refractory solid tumors
    Wayne L Furman
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794l, USA
    J Clin Oncol 24:563-70. 2006
    ....
  33. pmc PET/CT for staging and follow-up of pediatric nasopharyngeal carcinoma
    Daniel K L Cheuk
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 3678, USA
    Eur J Nucl Med Mol Imaging 39:1097-106. 2012
    ..In this investigation, we studied the utility of FDG PET/CT in children with NPC...
  34. pmc Dose escalation of intravenous irinotecan using oral cefpodoxime: a phase I study in pediatric patients with refractory solid tumors
    Lisa M McGregor
    Department of Oncology, St Jude Children s Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA
    Pediatr Blood Cancer 58:372-9. 2012
    ..Administration of an oral cephalosporin allowed advancement of the dosage of oral irinotecan. This study investigates whether administration of an oral cephalosporin increases the maximum tolerated dose (MTD) of intravenous irinotecan...
  35. ncbi request reprint Analysis of prognostic factors in ewing sarcoma family of tumors: review of St. Jude Children's Research Hospital studies
    Carlos Rodriguez-Galindo
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Cancer 110:375-84. 2007
    ..As new treatments are developed, a critical review of data from past treatment eras is needed to identify clinically relevant risk groups...
  36. pmc Successful treatment of early detected trilateral retinoblastoma using standard infant brain tumor therapy
    Karen D Wright
    Department of Oncology, Division of Neuro Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 3678, USA
    Pediatr Blood Cancer 55:570-2. 2010
    ..Early diagnosis of trilateral retinoblastoma may facilitate the use of less intensive therapeutic approaches and result in excellent outcomes in these patients...
  37. ncbi request reprint Protocol-based treatment for children with cancer in low income countries in Latin America: a report on the recent meetings of the Monza International School of Pediatric Hematology/Oncology (MISPHO)--part II
    Scott C Howard
    International Outreach Program and Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Pediatr Blood Cancer 48:486-90. 2007
    ..Despite the use of all-trans-retinoic acid during induction for acute promyelocytic leukemia, the incidence of fatal hemorrhage remains unacceptably high...
  38. pmc The effect of cancer therapies on pediatric anophthalmic sockets
    Yevgeniy Shildkrot
    Department of Ophthalmology, Hamilton Eye Institute, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    Ophthalmology 118:2480-6. 2011
    ..To determine the impact of chemotherapy or external beam radiotherapy (EBRT) on pediatric anophthalmic sockets...
  39. pmc Retrospective study of the surgical management and outcome of nonrhabdomyosarcoma soft tissue sarcomas of the groin and axilla in children
    Gideon Karplus
    Department of Surgery, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Pediatr Surg 44:1972-6. 2009
    ..The incidence of pediatric nonrhabdomyosarcoma soft tissue sarcomas (NRSTSs) of the groin and axilla is unknown, and the optimal surgical approach to these patients is unclear...
  40. pmc Functional neuroimaging to characterize visual system development in children with retinoblastoma
    Scott M Barb
    Department of Radiological Sciences, St Jude Children s Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105 2794, USA
    Invest Ophthalmol Vis Sci 52:2619-26. 2011
    ..To use functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI) to investigate visual system development in children being treated for retinoblastoma...
  41. ncbi request reprint Transfer of complex frontline anticancer therapy to a developing country: the St. Jude osteosarcoma experience in Chile
    Gaston K Rivera
    International Outreach Program, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Pediatr Blood Cancer 50:1143-6. 2008
    ..Jude Children's Research Hospital (sponsor) and Calvo Mackenna Hospital (CMH, partner), a public pediatric hospital and national center for the treatment of bone tumors in Santiago, Chile...
  42. ncbi request reprint Episcleral plaque brachytherapy for retinoblastoma
    Thomas E Merchant
    Division of Radiation Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Pediatr Blood Cancer 43:134-9. 2004
    ..The purpose of this study was to report our experience using episcleral plaque brachytherapy (EPBRT) to treat retinoblastoma and to demonstrate its applicability in multimodality treatment...
  43. pmc Coexpression of normally incompatible developmental pathways in retinoblastoma genesis
    Justina McEvoy
    Department of Developmental Neurobiology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Cancer Cell 20:260-75. 2011
    ..Furthermore, neurotransmitter receptors, transporters, and biosynthetic enzymes are expressed in human retinoblastoma, and targeted disruption of these pathways reduces retinoblastoma growth in vivo and in vitro...
  44. pmc Second cancers in patients with the Ewing sarcoma family of tumours
    Fariba Navid
    Department of Oncology, St Jude Children s Research Hospital, 332 N Lauderdale Street, Memphis, TN 38105, United States
    Eur J Cancer 44:983-91. 2008
    ..Patients are at risk of second malignancies (SM) after treatment for Ewing sarcoma family of tumours (ESFT)...
  45. doi request reprint Predictive factors of invasion in eyes with retinoblastoma enucleated after eye salvage treatments
    Julia Balaguer
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Pediatr Blood Cancer 52:351-6. 2009
    ..The impact of chemotherapy, focal therapies, radiation and co-existing ocular morbidities on histology of eyes with retinoblastoma enucleated following chemoreduction is not well known...
  46. ncbi request reprint Incidence of new tumor formation in patients with hereditary retinoblastoma treated with primary systemic chemotherapy: is there a preventive effect?
    Matthew W Wilson
    Department of Ophthalmology Hamilton Eye Institute, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    Ophthalmology 114:2077-82. 2007
    ..To report the incidence of new tumor formation in hereditary retinoblastoma patients treated with primary systemic chemotherapy...
  47. doi request reprint A clinicopathological correlation of 67 eyes primarily enucleated for advanced intraocular retinoblastoma
    Matthew W Wilson
    Hamilton Eye Institute, Memphis, TN 38163, USA
    Br J Ophthalmol 95:553-8. 2011
    ..To correlate the clinical and histopathological findings of eyes primarily enucleated for advanced intraocular retinoblastoma...
  48. ncbi request reprint Efficacy of combined surgery and irradiation for localized Ewings sarcoma family of tumors
    Matthew J Krasin
    Division of Radiation Oncology, Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Pediatr Blood Cancer 43:229-36. 2004
    ..Local failure rates for patients who received combined surgery and RT were reviewed to determine outcome and prognostic factors...
  49. ncbi request reprint Immunohistochemical detection of multidrug-resistant protein expression in retinoblastoma treated by primary enucleation
    Matthew W Wilson
    Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    Invest Ophthalmol Vis Sci 47:1269-73. 2006
    ..To compare the expression of multidrug-resistant proteins in retinoblastoma tumors among eyes treated with primary enucleation...
  50. ncbi request reprint Effect of fractionated ifosfamide on the pharmacokinetics of irinotecan in pediatric patients with osteosarcoma
    Kristine R Crews
    Department of Pharmaceutical Sciences, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    J Pediatr Hematol Oncol 26:764-7. 2004
    ..The reduced area under the curve to the active metabolite SN-38 during ifosfamide therapy predicts a compromised efficacy of irinotecan in this combination...
  51. ncbi request reprint Retinoblastoma metastatic to the ovary in a patient with Waardenburg syndrome
    Darius M Moshfeghi
    Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    Am J Ophthalmol 133:716-8. 2002
    ..To report a child with retinoblastoma and Waardenburg syndrome who developed ovarian metastases...
  52. pmc A phase 1/pilot study of radiofrequency ablation for the treatment of recurrent pediatric solid tumors
    Fredric A Hoffer
    Department of Radiological Sciences, St Jude Children s Research Hospital, and Department of Pediatrics, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA
    Cancer 115:1328-37. 2009
    ..This prospective study was designed to be the first to evaluate the toxicity of radiofrequency ablation (RFA) in patients with recurrent pediatric solid tumors...
  53. pmc Comparison of two methods for carboplatin dosing in children with retinoblastoma
    Steven Allen
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Pediatr Blood Cancer 55:47-54. 2010
    ..Carboplatin is the most effective drug in retinoblastoma but systemic clearance is variable in young patients. While most regimens use a flat dose, individualized targeting may provide a more adjusted systemic exposure...
  54. ncbi request reprint UGT1A1 promoter genotype correlates with SN-38 pharmacokinetics, but not severe toxicity in patients receiving low-dose irinotecan
    Clinton F Stewart
    Department of Pharmaceutical Sciences, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Clin Oncol 25:2594-600. 2007
    ....
  55. ncbi request reprint Infections in children and young adults with bone malignancies undergoing limb-sparing surgery
    Aditya H Gaur
    Department of Infectious Diseases, St Jude Children s Research Hospital, 332 N Lauderdale Street, Memphis, TN 38105, USA
    Cancer 104:602-10. 2005
    ..The epidemiology, risk factors, and efficacy of therapy for infections complicating limb-sparing surgery (LSS) are not understood completely...
  56. doi request reprint Childhood hemangiopericytoma: review of St Jude Children's Research Hospital
    Israel Fernandez-Pineda
    Department of Surgery, St Jude Children s Research Hospital, Memphis, TN 38105 3678, USA
    J Pediatr Hematol Oncol 33:356-9. 2011
    ..Intracranial HPC represents a special subtype with a high proclivity toward recurrence and metastasis...
  57. ncbi request reprint Local control in childhood extremity sarcomas: salvaging limbs and sparing function
    Bhaskar N Rao
    Department of Surgery, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Med Pediatr Oncol 41:584-7. 2003
  58. pmc Development of retinoblastoma programs in Central America
    Judith A Wilimas
    International Outreach Program and Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Pediatr Blood Cancer 53:42-6. 2009
    ..Jude Children's Research Hospital, and the University of Tennessee Hamilton Eye Institute...
  59. ncbi request reprint Inactivation of the p53 pathway in retinoblastoma
    Nikia A Laurie
    Department of Developmental Neurobiology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Nature 444:61-6. 2006
    ..In addition, they support the idea that MDMX is a specific chemotherapeutic target for treating retinoblastoma...
  60. ncbi request reprint Neuronal differentiation and synaptogenesis in retinoblastoma
    Dianna A Johnson
    Department of Ophthalmology, College of Medicine, University of Tennessee Health Sciences Center, Memphis, USA
    Cancer Res 67:2701-11. 2007
    ..Instead, rosette formation reflects extensive cell-cell contacts between retinoblastoma cells in both early-stage (differentiated) and late-stage (dedifferentiated) tumors...
  61. ncbi request reprint Ewing sarcoma-family tumors that arise after treatment of primary childhood cancer
    Sheri L Spunt
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Cancer 107:201-6. 2006
    ..ESFT arising as a second cancer was reviewed and characterized at our childhood cancer center...
  62. doi request reprint Lack of correlation between the histologic and magnetic resonance imaging results of optic nerve involvement in eyes primarily enucleated for retinoblastoma
    Matthew W Wilson
    Hamilton Eye Institute, Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    Ophthalmology 116:1558-63. 2009
    ..To correlate the histologic and magnetic resonance imaging results of the optic nerve in eyes primarily enucleated for retinoblastoma...
  63. doi request reprint Orbital involvement in langerhans cell histiocytosis
    Houman Vosoghi
    Department of Ophthalmology, Hamilton Eye Institute, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA
    Ophthal Plast Reconstr Surg 25:430-3. 2009
    ..The authors studied a series of patients with Langerhans cell histiocytosis in an attempt to better define the incidence and significance of orbital involvement within the vast spectrum of the disease...
  64. ncbi request reprint Identification of a novel germ line variant hotspot mutant p53-R175L in pediatric adrenal cortical carcinoma
    Alina Nico West
    Departments of Interdisciplinary Sciences, University of Tennessee Health Science Center, Memphis, Tennessee 338105, USA
    Cancer Res 66:5056-62. 2006
    ..Therefore, not all hotspot mutants are functionally equivalent and the biochemical nature of the mutant may significantly influence clinical outcome. The implications of these results for genetic counseling are discussed...
  65. pmc Prognostic factors and long-term outcomes of childhood nasopharyngeal carcinoma
    Daniel Ka Leung Cheuk
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Cancer 117:197-206. 2011
    ..The authors studied the survival and long-term morbidities of children with nasopharyngeal carcinoma (NPC)...
  66. ncbi request reprint Extranodal Rosai-Dorfman disease in children
    Carlos Rodriguez-Galindo
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    J Pediatr Hematol Oncol 26:19-24. 2004
    ..The authors describe three patients with RDD who had exclusive extranodal disease in the head and neck area, in whom the clinical presentation mimicked other more common conditions...
  67. ncbi request reprint Natural history of moderate aplastic anemia in children
    Scott C Howard
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Pediatr Blood Cancer 43:545-51. 2004
    ..We evaluated the rate of progression to SAA...
  68. ncbi request reprint PET-CT in pediatric Langerhans cell histiocytosis
    Sue C Kaste
    Division of Diagnostic Imaging, Department of Radiological Sciences, St Jude Children s Research Hospital, 332 N Lauderdale, Memphis, TN 38105 2794, USA
    Pediatr Radiol 37:615-22. 2007
    ..We conclude that PET-CT information is clinically useful to evaluate disease activity and response to therapy and provides information that cannot be obtained from technetium 99m methylene diphosphonate bone scans or radiographs...
  69. doi request reprint Bronchioloalveolar carcinoma as a second malignancy in osteosarcoma survivors
    Jeffrey Lebensburger
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Pediatr Blood Cancer 53:499-501. 2009
    ..BAC may present as a solitary pulmonary nodule indistinguishable from a metastatic lesion and should be included in the differential diagnosis of pulmonary nodules in survivors of pediatric cancer...
  70. pmc Infrequent tumor initiative of the Children's Oncology Group: initial lessons learned and their impact on future plans
    Alberto S Pappo
    St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Clin Oncol 28:5011-6. 2010
    ..Furthermore, our initial experience has demonstrated to us the potential power of expanded cooperation and collaboration at a global level...
  71. ncbi request reprint Use of [18F]fluorodeoxyglucose positron emission tomography in evaluating locally recurrent and metastatic adrenocortical carcinoma
    Gavin C Mackie
    Department of Radiological Sciences, St Jude Children s Research Hospital, 332 North Lauderdale, Mail Stop 752, Memphis, Tennessee 38105 2794, USA
    J Clin Endocrinol Metab 91:2665-71. 2006
    ..Adrenocortical carcinomas are uncommon, and their evaluation by [(18)F]fluorodeoxyglucose positron emission tomography (FDG PET) has not been well evaluated...
  72. ncbi request reprint Nocturnal awakenings, sleep environment interruptions, and fatigue in hospitalized children with cancer
    Pamela S Hinds
    Division of Nursing Research, St Jude Children s Research Hospital, Memphis, TN, USA
    Oncol Nurs Forum 34:393-402. 2007
    ....
  73. doi request reprint Team management, twinning, and telemedicine in retinoblastoma: a 3-tier approach implemented in the first eye salvage program in Jordan
    Ibrahim Qaddoumi
    Department of Pediatric Oncology, King Hussein Cancer Centre KHCC, Amman, Jordan
    Pediatr Blood Cancer 51:241-4. 2008
    ..This study evaluated the outcome of retinoblastoma patients, when employing a telemedicine-based twinning program in Jordan...
  74. pmc Use of preclinical models to improve treatment of retinoblastoma
    Michael A Dyer
    Department of Developmental Neurobiology, St Jude Children s Research Hospital, Memphis, Tennessee, United States of America
    PLoS Med 2:e332. 2005
  75. ncbi request reprint Primary malignant peripheral nerve sheath tumor of the lung in a young child without neurofibromatosis type 1
    Samar A Muwakkit
    Children s Cancer Center of Lebanon, American University of Beirut, Beirut, Lebanon, and Department of Hematology and Oncology, St Jude Children s Research Hospital, Memphis, TN, USA
    Pediatr Blood Cancer 47:636-8. 2006
    ..MPNST of the lung has similar clinical and radiologic characteristics as pleuropulmonary blastoma. We suggest to include MPNST of the lung in the differential diagnosis of intrapulmonary masses in children...
  76. ncbi request reprint Retinoblastoma in a patient with an X;13 translocation and facial abnormalities consistent with 13q-syndrome
    Stephen J Laquis
    Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    Am J Ophthalmol 133:285-7. 2002
    ..To report a patient with an X;13 translocation and facial features of 13q-syndrome who developed retinoblastoma...
  77. ncbi request reprint Sister Mary Joseph's nodule as presenting sign of a desmoplastic small round cell tumor
    Leslie Doros
    Department of Pediatrics, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA
    Pediatr Blood Cancer 50:388-90. 2008
    ..The diagnosis of an intra-abdominal malignancy, most commonly a DSRCT, should be considered in the presence of an umbilical mass in a child...
  78. ncbi request reprint Gene expression profiling of childhood adrenocortical tumors
    Alina Nico West
    Interdisciplinary Science Program, University of Tennessee Health Science Center, Department of Biostatistics, St Jude Children s Research Hospital, Memphis 38105, USA
    Cancer Res 67:600-8. 2007
    ..Our findings lay the groundwork for establishing gene expression profiles that may aid in the diagnosis and prognosis of pediatric ACT, and in the identification of signaling pathways that contribute to this disease...
  79. ncbi request reprint Pyogenic hepatic abscess after percutaneous liver biopsy in a patient with sickle cell disease
    Marta B Garcia-Arias
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    J Pediatr Hematol Oncol 27:103-5. 2005
    ..The presence of a hepatic abscess should be considered in the differential diagnosis of atypical abdominal pain in patients with SCD...
  80. ncbi request reprint Heme oxygenase-1 messenger RNA expression is induced in peripheral blood mononuclear cells of pediatric cancer patients with systemic inflammatory response syndrome
    Jeffrey E Schmidt
    Division of Critical Care Medicine, Department of Developmental Neurobiology, St Jude Children s Research Hospital, University of Tennessee Health Science Center, Memphis, TN, USA
    Pediatr Crit Care Med 5:554-60. 2004
    ....
  81. pmc c-Myc augments gamma irradiation-induced apoptosis by suppressing Bcl-XL
    Kirsteen H Maclean
    Department of Biochemistry, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Mol Cell Biol 23:7256-70. 2003
    ..Therefore, MYC may sensitize tumor cells to DNA damage by suppressing Bcl-X...
  82. ncbi request reprint Incidence of anemia in children with solid tumors or Hodgkin disease
    Marilyn J Hockenberry
    Texas Children s Cancer Center, Texas Children s Hospital, Houston 77030, USA
    J Pediatr Hematol Oncol 24:35-7. 2002
    ..The long-term complications of anemia in children with cancer are unknown. Further investigation of the clinical significance of anemia, including its impact on quality of life, is warranted...
  83. ncbi request reprint Mortality rate of adrenocortical tumors in children under 15 years of age in Curitiba, Brazil
    Mara A D Pianovski
    Department of Pediatric, Hematology and Pediatric Oncology Division, Clínicas Hospital of the Federal University of Paraná, Brazil
    Pediatr Blood Cancer 47:56-60. 2006
    ..An inherited germline mutation in the p53 gene (TP53 R337H) is detected in virtually all children with ACT in this region and accounts for the excess cases observed...
  84. ncbi request reprint Intra-arterial cisplatin in osteosarcoma: same question, different answer
    Bhaskar N Rao
    Ann Surg Oncol 10:481-3. 2003
  85. ncbi request reprint Granulocyte-macrophage colony stimulating factor and immunosuppression in the treatment of pediatric acquired severe aplastic anemia
    Michael R Jeng
    Department of Pediatrics, Stanford University School of Medicine, Stanford, California 94305, USA
    Pediatr Blood Cancer 45:170-5. 2005
    ..The addition of G-CSF to IS shortens the time to neutrophil count recovery, but may not improve overall survival. Because GM-CSF acts differently than G-CSF, its use in combination with IS may be different...
  86. ncbi request reprint Impact of an education program on late diagnosis of retinoblastoma in Honduras
    Christopher Leander
    Weill Cornell Medical College, New York, New York, USA
    Pediatr Blood Cancer 49:817-9. 2007
    ..Early diagnosis is necessary to improve the survival of children with retinoblastoma in these countries...
  87. ncbi request reprint Reducing irinotecan-associated diarrhea in children
    Lars M Wagner
    Division of Pediatric Hematology Oncology, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Pediatr Blood Cancer 50:201-7. 2008
    ..This approach is feasible in children and allows for tolerance of higher doses of protracted irinotecan...
  88. ncbi request reprint The addition of ifosfamide/etoposide to cisplatin/teniposide improves the survival of children with retinoblastoma and orbital involvement
    Célia Beatriz Gianotti Antoneli
    Pediatrics Department, Centro de Tratamento e Pesquisa Hospital do Cancer A C Camargo, Sao Paulo, Brazil
    J Pediatr Hematol Oncol 29:700-4. 2007
    ..2%, respectively, for patients treated during periods I and II (P=0.061). The addition of ifosfamide/etoposide to chemotherapy with cisplatin/teniposide improves survival in these patients, but further studies are still necessary...
  89. ncbi request reprint Osteosarcoma of the pelvis in children and young adults: the St. Jude Children's Research Hospital experience
    Raya Saab
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Cancer 103:1468-74. 2005
    ..Pelvic osteosarcomas are difficult to resect. The authors reviewed their institution's experience with patients who had such tumors to characterize the patients' clinical findings and to assess the impact of surgical resection on outcome...
  90. ncbi request reprint Corneal juvenile xanthogranuloma in a 4-month-old child
    Emily D Ashmore
    Department of Ophthalmology, University of Tennessee Health Science Center, 956 Court Ave, D 228, Memphis, TN 38163, USA
    Arch Ophthalmol 121:117-8. 2003
  91. ncbi request reprint Germline TP53 R337H mutation is not sufficient to establish Li-Fraumeni or Li-Fraumeni-like syndrome
    Raul C Ribeiro
    Cancer Lett 247:353-5; author reply 356-8. 2007