Leslie L Robison

Summary

Affiliation: St. Jude Children's Research Hospital
Country: USA

Publications

  1. doi request reprint Late effects of acute lymphoblastic leukemia therapy in patients diagnosed at 0-20 years of age
    Leslie L Robison
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Hematology Am Soc Hematol Educ Program 2011:238-42. 2011
  2. pmc The Childhood Cancer Survivor Study: a National Cancer Institute-supported resource for outcome and intervention research
    Leslie L Robison
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    J Clin Oncol 27:2308-18. 2009
  3. doi request reprint Opportunities and challenges of establishing a nationwide strategy for adolescents and young adults in Canada with cancer: impressions from the Toronto workshop
    Leslie L Robison
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Cancer 117:2351-4. 2011
  4. pmc Treatment-associated subsequent neoplasms among long-term survivors of childhood cancer: the experience of the Childhood Cancer Survivor Study
    Leslie L Robison
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN 38105 3678, USA
    Pediatr Radiol 39:S32-7. 2009
  5. pmc Physiologic frailty as a sign of accelerated aging among adult survivors of childhood cancer: a report from the St Jude Lifetime cohort study
    Kirsten K Ness
    Kirsten K Ness, Kevin R Krull, Kendra E Jones, Daniel A Mulrooney, Gregory T Armstrong, Daniel M Green, Wassim Chemaitilly, Webb A Smith, Carmen L Wilson, Kyla Shelton, Deo Kumar Srivastava, Sabeen Ali, Leslie L Robison, Melissa M Hudson, St Jude Children s Research Hospital, Memphis, TN Charles A Sklar, Memorial Sloan Kettering Cancer Center, New York, NY
    J Clin Oncol 31:4496-503. 2013
  6. pmc Late mortality among 5-year survivors of childhood cancer: a summary from the Childhood Cancer Survivor Study
    Gregory T Armstrong
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Clin Oncol 27:2328-38. 2009
  7. pmc Clinical ascertainment of health outcomes among adults treated for childhood cancer
    Melissa M Hudson
    Division of Cancer Survivorship, Department of Oncology, St Jude Children s Research Hospital and the University of Tennessee College of Medicine, Memphis, TN 38105, USA
    JAMA 309:2371-81. 2013
  8. pmc Neurocognitive function and CNS integrity in adult survivors of childhood hodgkin lymphoma
    Kevin R Krull
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, 262 Danny Thomas Place, MS 735, Memphis, TN 38105 3678, USA
    J Clin Oncol 30:3618-24. 2012
  9. pmc Prospective medical assessment of adults surviving childhood cancer: study design, cohort characteristics, and feasibility of the St. Jude Lifetime Cohort study
    Melissa M Hudson
    Department of Oncology, Division of Cancer Survivorship, St Jude Children s Research Hospital and the University of Tennessee College of Medicine, Memphis, Tennessee, USA
    Pediatr Blood Cancer 56:825-36. 2011
  10. pmc Fertility of female survivors of childhood cancer: a report from the childhood cancer survivor study
    Daniel M Green
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    J Clin Oncol 27:2677-85. 2009

Research Grants

  1. CANCER EPIDEMIOLOGY
    Leslie Robison; Fiscal Year: 2002
  2. CHILDHOOD CANCER SURVIVOR STUDY
    Leslie Robison; Fiscal Year: 2005
  3. CHILDHOOD CANCER SURVIVOR STUDY
    Leslie Robison; Fiscal Year: 2007

Collaborators

Detail Information

Publications129 found, 100 shown here

  1. doi request reprint Late effects of acute lymphoblastic leukemia therapy in patients diagnosed at 0-20 years of age
    Leslie L Robison
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Hematology Am Soc Hematol Educ Program 2011:238-42. 2011
    ....
  2. pmc The Childhood Cancer Survivor Study: a National Cancer Institute-supported resource for outcome and intervention research
    Leslie L Robison
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    J Clin Oncol 27:2308-18. 2009
    ....
  3. doi request reprint Opportunities and challenges of establishing a nationwide strategy for adolescents and young adults in Canada with cancer: impressions from the Toronto workshop
    Leslie L Robison
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Cancer 117:2351-4. 2011
    ..It is concluded that the Canadian healthcare and advocacy communities are well-positioned to have a major impact and assume a leadership role in AYA cancer care...
  4. pmc Treatment-associated subsequent neoplasms among long-term survivors of childhood cancer: the experience of the Childhood Cancer Survivor Study
    Leslie L Robison
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN 38105 3678, USA
    Pediatr Radiol 39:S32-7. 2009
    ..The CCSS has provided important data to quantify radiation-associated risk for subsequent cancers including neoplasms of the breast, thyroid and central nervous system...
  5. pmc Physiologic frailty as a sign of accelerated aging among adult survivors of childhood cancer: a report from the St Jude Lifetime cohort study
    Kirsten K Ness
    Kirsten K Ness, Kevin R Krull, Kendra E Jones, Daniel A Mulrooney, Gregory T Armstrong, Daniel M Green, Wassim Chemaitilly, Webb A Smith, Carmen L Wilson, Kyla Shelton, Deo Kumar Srivastava, Sabeen Ali, Leslie L Robison, Melissa M Hudson, St Jude Children s Research Hospital, Memphis, TN Charles A Sklar, Memorial Sloan Kettering Cancer Center, New York, NY
    J Clin Oncol 31:4496-503. 2013
    ..9% of individuals 65 years old and older (9.6% of women; 5.2% of men), has not been assessed among adult childhood cancer survivors (CCS). We estimated the prevalence of frailty and examined associations with morbidity and mortality...
  6. pmc Late mortality among 5-year survivors of childhood cancer: a summary from the Childhood Cancer Survivor Study
    Gregory T Armstrong
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Clin Oncol 27:2328-38. 2009
    ....
  7. pmc Clinical ascertainment of health outcomes among adults treated for childhood cancer
    Melissa M Hudson
    Division of Cancer Survivorship, Department of Oncology, St Jude Children s Research Hospital and the University of Tennessee College of Medicine, Memphis, TN 38105, USA
    JAMA 309:2371-81. 2013
    ..A large population of survivors has not been evaluated using a comprehensive systematic clinical assessment to determine the prevalence of chronic health conditions...
  8. pmc Neurocognitive function and CNS integrity in adult survivors of childhood hodgkin lymphoma
    Kevin R Krull
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, 262 Danny Thomas Place, MS 735, Memphis, TN 38105 3678, USA
    J Clin Oncol 30:3618-24. 2012
    ..The aim of this study was to examine neurocognitive and brain imaging outcomes in adult survivors of childhood HL...
  9. pmc Prospective medical assessment of adults surviving childhood cancer: study design, cohort characteristics, and feasibility of the St. Jude Lifetime Cohort study
    Melissa M Hudson
    Department of Oncology, Division of Cancer Survivorship, St Jude Children s Research Hospital and the University of Tennessee College of Medicine, Memphis, Tennessee, USA
    Pediatr Blood Cancer 56:825-36. 2011
    ..Jude Children's Research Hospital (SJCRH) is establishing a lifetime cohort of survivors...
  10. pmc Fertility of female survivors of childhood cancer: a report from the childhood cancer survivor study
    Daniel M Green
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    J Clin Oncol 27:2677-85. 2009
    ..This study was undertaken to determine the effect, if any, of treatment for cancer diagnosed during childhood or adolescence on fertility...
  11. pmc Risk factors for obesity in adult survivors of childhood cancer: a report from the Childhood Cancer Survivor Study
    Daniel M Green
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, 262 Danny Thomas Place, Mail Stop 735, Memphis, TN 38105 2794, USA
    J Clin Oncol 30:246-55. 2012
    ..Many Childhood Cancer Survivor Study (CCSS) participants are at increased risk for obesity. The etiology of their obesity is likely multifactorial but not well understood...
  12. pmc Long-term outcomes among adult survivors of childhood central nervous system malignancies in the Childhood Cancer Survivor Study
    Gregory T Armstrong
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, 262 Danny Thomas Place, Mail Stop 735, Memphis, TN 38105, USA
    J Natl Cancer Inst 101:946-58. 2009
    ....
  13. pmc Association between the prevalence of symptoms and health-related quality of life in adult survivors of childhood cancer: a report from the St Jude Lifetime Cohort study
    I Chan Huang
    I Chan Huang, Kelly Kenzik, and Elizabeth Shenkman, University of Florida, Gainesville, FL and Tara M Brinkman, James G Gurney, Kirsten K Ness, Jennifer Lanctot, Leslie L Robison, Melissa M Hudson, and Kevin R Krull, St Jude Children s Research Hospital, Memphis, TN
    J Clin Oncol 31:4242-51. 2013
    ..We investigated the association between prevalence of symptoms and health-related quality of life (HRQOL) in adult survivors of childhood cancer enrolled in the St Jude Lifetime Cohort study...
  14. pmc Long-term decline in intelligence among adult survivors of childhood acute lymphoblastic leukemia treated with cranial radiation
    Kevin R Krull
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN 38105 3678, USA
    Blood 122:550-3. 2013
    ..This trial was registered at clinicaltrials.gov as no. NCT00760656. ..
  15. pmc Physical performance limitations in the Childhood Cancer Survivor Study cohort
    Kirsten K Ness
    Departments of Epidemiology and Cancer Control, Oncology, and Radiologic Sciences, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Clin Oncol 27:2382-9. 2009
    ....
  16. doi request reprint Pulmonary outcomes in survivors of childhood central nervous system malignancies: a report from the Childhood Cancer Survivor Study
    Tseng Tien Huang
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, Tennessee
    Pediatr Blood Cancer 61:319-25. 2014
    ..This study enumerates the incidence of pulmonary dysfunction and explores associations between craniospinal irradiation (CSI) and pulmonary dysfunction among survivors of childhood CNS tumors...
  17. pmc Survivor typologies predict medical surveillance participation: the childhood cancer survivor study
    Cheryl L Cox
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    Psychooncology 22:1534-42. 2013
    ..Adult survivors of childhood cancer adhere poorly to recommended medical surveillance. We sought to identify modifiable factors that contribute to non-adherence...
  18. doi request reprint Dexamethasone exposure and memory function in adult survivors of childhood acute lymphoblastic leukemia: A report from the SJLIFE cohort
    Michelle N Edelmann
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, Tennessee
    Pediatr Blood Cancer 60:1778-84. 2013
    ..As glucocorticoids influence hippocampal function, we investigated memory networks in survivors of childhood ALL treated with dexamethasone or prednisone...
  19. pmc Prevalence and predictors of prescription psychoactive medication use in adult survivors of childhood cancer: a report from the Childhood Cancer Survivor Study
    Tara M Brinkman
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Cancer Surviv 7:104-14. 2013
    ....
  20. pmc Fertility of male survivors of childhood cancer: a report from the Childhood Cancer Survivor Study
    Daniel M Green
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, 262 Danny Thomas Place, Mail Stop 735, Memphis, TN 38105 2794, USA
    J Clin Oncol 28:332-9. 2010
    ..This study was undertaken to determine the effect of treatment for childhood cancer on male fertility...
  21. pmc Neurocognitive functioning and health-related behaviours in adult survivors of childhood cancer: a report from the Childhood Cancer Survivor Study
    Kevin R Krull
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN 38105 3678, United States
    Eur J Cancer 47:1380-8. 2011
    ..Positive health-related behaviours are essential for the future wellbeing of childhood cancer survivors, though relatively few maintain healthy behaviours into adulthood...
  22. pmc Decreased fertility among female childhood cancer survivors who received 22-27 Gy hypothalamic/pituitary irradiation: a report from the Childhood Cancer Survivor Study
    Daniel M Green
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Fertil Steril 95:1922-7, 1927.e1. 2011
    ..To evaluate the effect of hypothalamic/pituitary radiation (HPT RT) dose on the occurrence of first pregnancy...
  23. doi request reprint Suicide ideation and associated mortality in adult survivors of childhood cancer
    Tara M Brinkman
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, Tennessee
    Cancer 120:271-7. 2014
    ....
  24. pmc Fatigue, vitality, sleep, and neurocognitive functioning in adult survivors of childhood cancer: a report from the Childhood Cancer Survivor Study
    Nancy R Clanton
    Department of Psychology, St Jude Children s Research Hospital, Memphis, Tennessee
    Cancer 117:2559-68. 2011
    ..Long-term survivors of childhood cancer are at risk for fatigue, sleep problems, and neurocognitive impairment, although the association between these outcomes has not been previously examined...
  25. doi request reprint Chemotherapy-related neuropathic symptoms and functional impairment in adult survivors of extracranial solid tumors of childhood: results from the St. Jude Lifetime Cohort Study
    Kirsten K Ness
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN, USA
    Arch Phys Med Rehabil 94:1451-7. 2013
    ..To ascertain prevalence of peripheral sensory and motor neuropathy, and to evaluate impairments in relation to function...
  26. pmc Renal carcinoma after childhood cancer: a report from the childhood cancer survivor study
    Carmen L Wilson
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, 262 Danny Thomas Pl, MS 735, Memphis, TN 38105, USA
    J Natl Cancer Inst 105:504-8. 2013
    ..8, 95% CI = 1.6 to 9.3) and platinum-based chemotherapy (RR = 3.5, 95% CI = 1.0 to 11.2). To our knowledge, this is the first report of an association between cisplatin and subsequent renal carcinoma among survivors of childhood cancer...
  27. pmc Psychoactive medication use and neurocognitive function in adult survivors of childhood cancer: a report from the Childhood Cancer Survivor study
    Tara M Brinkman
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Pediatr Blood Cancer 60:486-93. 2013
    ..Psychoactive medication treatment has been associated with adverse effects on specific neurocognitive processes in non-cancer populations, yet these associations have not been examined in adult survivors of childhood cancer...
  28. pmc Impact of radiation and chemotherapy on risk of dental abnormalities: a report from the Childhood Cancer Survivor Study
    Sue C Kaste
    Department of Radiological Sciences, St Jude Children s Research Hospital, and Department of Radiology, University of Tennessee School of Health Sciences, Memphis, Tennessee 38105, USA
    Cancer 115:5817-27. 2009
    ..The current study was performed to describe frequencies and risk factors of altered oral health and odontogenesis in childhood cancer survivors...
  29. pmc Occurrence of multiple subsequent neoplasms in long-term survivors of childhood cancer: a report from the childhood cancer survivor study
    Gregory T Armstrong
    MSCE, Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, 262 Danny Thomas Pl, Mail Stop 735, Memphis, TN, USA
    J Clin Oncol 29:3056-64. 2011
    ..Those surviving the first SN (SN1) remain at risk to develop multiple SNs. Because SNs are a common cause of late morbidity and mortality, characterization of rates of multiple SNs is needed...
  30. pmc Promoting physical activity in childhood cancer survivors: results from the Childhood Cancer Survivor Study
    Cheryl L Cox
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Cancer 115:642-54. 2009
    ..The authors of this report sought to identify modifiable factors that influence survivors' participation in physical activity...
  31. doi request reprint The cyclophosphamide equivalent dose as an approach for quantifying alkylating agent exposure: a report from the Childhood Cancer Survivor Study
    Daniel M Green
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, Tennessee
    Pediatr Blood Cancer 61:53-67. 2014
    ..The widely used Alkylating Agent Dose (AAD) score is derived from the drug dose distribution of the study population and thus cannot be used for comparisons across populations as each will have a unique distribution of drug doses...
  32. pmc Modifiable risk factors and major cardiac events among adult survivors of childhood cancer
    Gregory T Armstrong
    Gregory T Armstrong, Daniel A Mulrooney, and Leslie L Robison, St Jude Children s Research Hospital, Memphis, TN Kevin C Oeffinger and Charles A Sklar, Memorial Sloan Kettering Cancer Center, New York, NY Yan Chen and Yutaka Yasui, University of Alberta, Edmonton, Alberta, Canada Toana Kawashima, Wendy Leisenring, and Eric J Chow, Fred Hutchinson Cancer Research Center Eric J Chow, Seattle Children s Hospital, Seattle, WA Marilyn Stovall and Jean Bernard Durand, The University of Texas MD Anderson Cancer Center, Houston, TX and Ann C Mertens, William Border, and Lillian R Meacham, Emory University, Atlanta, GA
    J Clin Oncol 31:3673-80. 2013
    ..To evaluate the relative contribution of modifiable cardiovascular risk factors on the development of major cardiac events in aging adult survivors of childhood cancer...
  33. pmc Screening adult survivors of childhood cancer for cardiomyopathy: comparison of echocardiography and cardiac magnetic resonance imaging
    Gregory T Armstrong
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, 262 Danny Thomas Place, Mailstop 735, Memphis, TN 38105, USA
    J Clin Oncol 30:2876-84. 2012
    ....
  34. pmc High-risk populations identified in Childhood Cancer Survivor Study investigations: implications for risk-based surveillance
    Melissa M Hudson
    St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Clin Oncol 27:2405-14. 2009
    ....
  35. pmc Region-specific radiotherapy and neuropsychological outcomes in adult survivors of childhood CNS malignancies
    Gregory T Armstrong
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, 262 Danny Thomas Place, MS 735, Memphis, TN 38105 3678, USA
    Neuro Oncol 12:1173-86. 2010
    ..Survivors with a history of radiation exposure to temporal brain regions are at increased risk for impairment in memory and social functioning...
  36. pmc Smokeless and dual tobacco use among males surviving childhood cancer: a report from the Childhood Cancer Survivor Study
    James L Klosky
    Departments of Psychology, Biostatistics, Epidemiology and Cancer Control, and Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Cancer Epidemiol Biomarkers Prev 22:1025-9. 2013
    ..Screening and intervening for smokeless tobacco/dual tobacco use in childhood cancer survivors will reduce tobacco-related morbidity and mortality...
  37. pmc Evaluation of memory impairment in aging adult survivors of childhood acute lymphoblastic leukemia treated with cranial radiotherapy
    Gregory T Armstrong
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Natl Cancer Inst 105:899-907. 2013
    ..Cranial radiotherapy (CRT) is a known risk factor for neurocognitive impairment in survivors of childhood cancer and may increase risk for mild cognitive impairment and dementia in adulthood...
  38. pmc Assessment of potential bias from non-participation in a dynamic clinical cohort of long-term childhood cancer survivors: results from the St. Jude Lifetime Cohort Study
    Rohit P Ojha
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Pediatr Blood Cancer 60:856-64. 2013
    ..We compared available demographic, disease, and neighborhood level characteristics between participants and the source population to assess the potential for selection bias...
  39. pmc Lack of specificity of plasma concentrations of inhibin B and follicle-stimulating hormone for identification of azoospermic survivors of childhood cancer: a report from the St Jude lifetime cohort study
    Daniel M Green
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    J Clin Oncol 31:1324-8. 2013
    ..Although both the levels of follicle-stimulating hormone (FSH) and inhibin B are correlated with sperm concentration, their ability to predict azoospermia in survivors of childhood cancer remains uncertain...
  40. pmc Fractures among long-term survivors of childhood cancer: a report from the Childhood Cancer Survivor Study
    Carmen L Wilson
    Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Cancer 118:5920-8. 2012
    ..The objective of this study was to ascertain the prevalence of and risk factors for fractures among individuals participating in the Childhood Cancer Survivor Study (CCSS)...
  41. pmc Risky health behavior among adolescents in the childhood cancer survivor study cohort
    James L Klosky
    Department of Psychology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Pediatr Psychol 37:634-46. 2012
    ..To report the prevalence and comparison of cancer-linked health behaviors and identify risk factors associated with unhealthy behavior among adolescent siblings and cancer survivors...
  42. pmc Adolescent behavior and adult health status in childhood cancer survivors
    Kevin R Krull
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN 38105 3678, USA
    J Cancer Surviv 4:210-7. 2010
    ....
  43. pmc Abnormal timing of menarche in survivors of central nervous system tumors: A report from the Childhood Cancer Survivor Study
    Gregory T Armstrong
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Cancer 115:2562-70. 2009
    ..To the authors' knowledge, data regarding the risk of altered timing of menarche after higher dose radiotherapy (RT), as used in the treatment of central nervous system (CNS) tumors, are limited...
  44. pmc Survival and long-term health and cognitive outcomes after low-grade glioma
    Gregory T Armstrong
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, 262 Danny Thomas Place, Mail Stop 735, Memphis, TN 38105, USA
    Neuro Oncol 13:223-34. 2011
    ..Survivors of childhood LGG experience substantial long-term adverse effects that continue to increase well beyond the 5-year survival time point...
  45. doi request reprint A systematic review of dental late effects in survivors of childhood cancer
    Prasad L Gawade
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, Tennessee, 38105
    Pediatr Blood Cancer 61:407-16. 2014
    ..This summary provides information that will assist clinicians to prevent, detect, and facilitate early intervention for dental late effects...
  46. pmc Increased tricuspid regurgitant jet velocity by Doppler echocardiography in adult survivors of childhood cancer: a report from the St Jude Lifetime Cohort Study
    Gregory T Armstrong
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Clin Oncol 31:774-81. 2013
    ....
  47. pmc Neuromuscular impairments in adult survivors of childhood acute lymphoblastic leukemia: associations with physical performance and chemotherapy doses
    Kirsten K Ness
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, Tennessee 38138, USA
    Cancer 118:828-38. 2012
    ....
  48. pmc Predictors of inactive lifestyle among adult survivors of childhood cancer: a report from the Childhood Cancer Survivor Study
    Kirsten K Ness
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Cancer 115:1984-94. 2009
    ....
  49. pmc Characteristics of responders to a request for a buccal cell specimen among survivors of childhood cancer and their siblings
    Kirsten K Ness
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Pediatr Blood Cancer 55:165-70. 2010
    ..Analysis of biological samples in large cohort studies may provide insight into the mechanism of, and risk factors for, disease onset and progression...
  50. pmc Assessment of selection bias in clinic-based populations of childhood cancer survivors: a report from the childhood cancer survivor study
    Kirsten K Ness
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Pediatr Blood Cancer 52:379-86. 2009
    ....
  51. doi request reprint Survivors of childhood and adolescent cancer: life-long risks and responsibilities
    Leslie L Robison
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, 262 Danny Thomas Place, Memphis, Tennessee 38105, USA
    Nat Rev Cancer 14:61-70. 2014
    ....
  52. pmc Cerebral white matter integrity and executive function in adult survivors of childhood medulloblastoma
    Tara M Brinkman
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, Tennessee 38105 3678, USA
    Neuro Oncol 14:iv25-36. 2012
    ..Future research integrating diffusion tensor imaging should be a priority to more rigorously evaluate long-term consequences of cancer treatment and to inform cognitive intervention trials in this high-risk population...
  53. pmc Abdominal aortic calcification in young adult survivors of childhood acute lymphoblastic leukemia: results from the St. Jude Lifetime Cohort study
    James G Gurney
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Pediatr Blood Cancer 59:1307-9. 2012
    ..0, 4.3). The adjusted OR for AAC in men with low BMD was 3.1 (95% CL = 1.3, 7.3). A substantial proportion of adult survivors of childhood ALL have AAC and/or metabolic syndrome, suggestive of early atherosclerotic disease...
  54. doi request reprint Secondary colorectal carcinoma after childhood cancer
    Kerri Nottage
    St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Clin Oncol 30:2552-8. 2012
    ..We aimed to quantify the long-term risk of secondary CRC and identify treatment-related risk factors...
  55. pmc Survivor profiles predict health behavior intent: the Childhood Cancer Survivor Study
    Cheryl L Cox
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    Psychooncology 21:469-78. 2012
    ..Secondary objectives were to examine to what extent group membership co-varied with more static variables (e.g. demographics, disease, and treatment) and predicted intent for subsequent medical follow-up...
  56. pmc Statistical analysis of mixed recurrent event data with application to cancer survivor study
    Liang Zhu
    Department of Biostatistics, St Jude Children s Research Hospital, TN 38103, USA
    Stat Med 32:1954-63. 2013
    ..Finally, we apply it to a motivating study on childhood cancer survivors...
  57. pmc Lessons from the past: opportunities to improve childhood cancer survivor care through outcomes investigations of historical therapeutic approaches for pediatric hematological malignancies
    Melissa M Hudson
    Department of Oncology, St Jude Children s Research Hospital, 332 N Lauderdale, Memphis, TN 38105, USA
    Pediatr Blood Cancer 58:334-43. 2012
    ....
  58. doi request reprint Primary care management of the childhood cancer survivor
    Beth A Kurt
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Pediatr 152:458-66. 2008
  59. pmc Medical screening participation in the childhood cancer survivor study
    Cheryl L Cox
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, 332 N Lauderdale St, Memphis, TN 38105 2794, USA
    Arch Intern Med 169:454-62. 2009
    ..We identified treatment, survivor, physician, and contextual factors that may influence survivor adherence to recommended echocardiography and bone densitometry screening...
  60. pmc Association of muscle strength and bone mineral density in adult survivors of childhood acute lymphoblastic leukemia
    Emily D Joyce
    Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    Arch Phys Med Rehabil 92:873-9. 2011
    ....
  61. pmc Long-term effects of radiation exposure among adult survivors of childhood cancer: results from the childhood cancer survivor study
    Gregory T Armstrong
    Department of Epidemiology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Radiat Res 174:840-50. 2010
    ..Ongoing study of childhood cancer survivors is needed to establish long-term risks and to evaluate the impact of newer techniques such as conformal radiation therapy or proton-beam therapy...
  62. pmc Relevance of historical therapeutic approaches to the contemporary treatment of pediatric solid tumors
    Daniel M Green
    Department of Epidemiology, St Jude Children s Research Hospital Memphis, Memphis, Tennessee 38105 2794, USA
    Pediatr Blood Cancer 60:1083-94. 2013
    ..These similarities allow the use of historical patient cohorts to identify the late effects of successful therapy and to evaluate remedial interventions for these adverse effects...
  63. pmc Attentional and executive dysfunction as predictors of smoking within the Childhood Cancer Survivor Study cohort
    Lisa S Kahalley
    Department of Behavioral Medicine, St Jude Children s Research Hospital, Memphis, TN, USA
    Nicotine Tob Res 12:344-54. 2010
    ..The present study explores whether the attentional and executive functioning (EF) deficits associated with cancer and treatment place survivors of childhood cancer at increased risk for smoking...
  64. doi request reprint The impact of limitations in physical, executive, and emotional function on health-related quality of life among adult survivors of childhood cancer: a report from the Childhood Cancer Survivor Study
    Kirsten K Ness
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Arch Phys Med Rehabil 89:128-36. 2008
    ....
  65. doi request reprint Acute lymphoblastic leukaemia
    Ching Hon Pui
    Department of Oncology, St Jude Children s Research Hospital and University of Tennessee Health Science Center, Memphis, TN 38105, USA
    Lancet 371:1030-43. 2008
    ....
  66. doi request reprint Safety of growth hormone treatment in patients previously treated for cancer
    Wassim Chemaitilly
    Division of Endocrinology, Department of Pediatric Medicine, St Jude Children s Research Hospital, Memphis, TN 38105 3678, USA
    Endocrinol Metab Clin North Am 41:785-92. 2012
    ..The review focuses on the risk of disease recurrence and second neoplasm occurrence with special attention to data on childhood cancer survivors...
  67. doi request reprint Semiparametric transformation models for joint analysis of multivariate recurrent and terminal events
    Liang Zhu
    Department of Biostatistics, St Jude Children s Research Hospital, Memphis, TN 38105, U S A
    Stat Med 30:3010-23. 2011
    ..The method is applied to a set of bivariate recurrent event data arising from a long-term follow-up study of childhood cancer survivors...
  68. pmc Long-term risk for subsequent leukemia after treatment for childhood cancer: a report from the Childhood Cancer Survivor Study
    Kerri Nottage
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN, USA
    Blood 117:6315-8. 2011
    ..9-6.0). Median survival from diagnosis of subsequent leukemia was 2 years. This is the first description of a statistically significant increased risk of subsequent leukemia ≥ 15 years from primary diagnosis of childhood cancer...
  69. pmc Temporal trends in cause-specific late mortality among 5-year survivors of childhood cancer
    Gregory T Armstrong
    MSCE, Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, 262 Danny Thomas Place, Mail Stop 735, Memphis, TN 38105, USA
    J Clin Oncol 28:1224-31. 2010
    ..We investigated changes in patterns of late mortality over time and cause-specific attribution of late-mortality among 5-year survivors...
  70. ncbi request reprint Survival and late mortality in long-term survivors of pediatric CNS tumors
    E Brannon Morris
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Clin Oncol 25:1532-8. 2007
    ..To describe the pattern of survival and late mortality among contemporary long-term survivors of pediatric CNS tumor...
  71. ncbi request reprint Long-term health status among survivors of childhood cancer: does sex matter?
    Gregory T Armstrong
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Clin Oncol 25:4477-89. 2007
    ..With greater knowledge of sex-specific risks, the potential application of sex-specific therapy designed to avoid poor long-term adverse outcomes may become a viable strategy...
  72. pmc Reliability and validity of the Childhood Cancer Survivor Study Neurocognitive Questionnaire
    Kevin R Krull
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Cancer 113:2188-97. 2008
    ..This study reports the results of a questionnaire developed to identify those survivors who may be experiencing neurocognitive problems...
  73. ncbi request reprint Minority adult survivors of childhood cancer: a comparison of long-term outcomes, health care utilization, and health-related behaviors from the childhood cancer survivor study
    Sharon M Castellino
    Department of Pediatrics, East Tennessee State University Quillen College of Medicine, Johnson City, St Jude Children s Research Hospital, Memphis, TN, USA
    J Clin Oncol 23:6499-507. 2005
    ..To determine the influence of race/ethnicity on outcomes in the Childhood Cancer Survivor Study (CCSS)...
  74. ncbi request reprint Childhood cancer epidemiology in low-income countries
    Scott C Howard
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Cancer 112:461-72. 2008
    ..POND4kids.org), which allows collection, analysis, and sharing of data...
  75. pmc Trial design: The St. Jude Children's Research Hospital Cancer Survivors Tobacco Quit Line study
    Taghrid Asfar
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Contemp Clin Trials 31:82-91. 2010
    ..Such evidence can lead as well to the dissemination of this intervention to other medically compromised populations...
  76. ncbi request reprint Long-term outcomes of adult survivors of childhood cancer
    Leslie L Robison
    Department of Pediatrics, University of Minnesota Medical School and Cancer Center, Minneapolis, USA
    Cancer 104:2557-64. 2005
    ..The ongoing evaluation of large and diverse cohorts of cancer survivors will aid in further identifying individuals who should be the target of innovative intervention strategies...
  77. pmc Retinoblastoma: one world, one vision
    Carlos Rodriguez-Galindo
    Department of Oncology, St Jude Children s Research Hospital, 332 N Lauderdale, Memphis, TN 38105, USA
    Pediatrics 122:e763-70. 2008
    ....
  78. ncbi request reprint The cancer screening practices of adult survivors of childhood cancer: a report from the Childhood Cancer Survivor Study
    Mark W Yeazel
    Department of Family Practice and Community Health, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA
    Cancer 100:631-40. 2004
    ..The current study characterized the self-reported cancer screening practices of adult survivors of childhood cancer...
  79. ncbi request reprint An examination of the dental utilization practices of adult survivors of childhood cancer: a report from the Childhood Cancer Survivor Study
    Mark W Yeazel
    University of Minnesota Medical School, Department of Family Practice and Community Health, Mayo Medical Code 381, 420 Delaware Street, SE, Minneapolis, MN 55455, USA
    J Public Health Dent 64:50-4. 2004
    ..This study characterized the self-reported dental utilization practice of long-term survivors of childhood cancer, a group at increased risk for treatment-induced dental abnormalities...
  80. ncbi request reprint Childhood cancer survivors' knowledge about their past diagnosis and treatment: Childhood Cancer Survivor Study
    Nina S Kadan-Lottick
    Department of Pediatrics, 420 Delaware St SE, Mayo Mail Code 715, Minneapolis, MN 55455, USA
    JAMA 287:1832-9. 2002
    ..This knowledge is necessary to motivate them to seek medical follow-up and to report essential history to health care professionals...
  81. ncbi request reprint The Minneapolis-Manchester Quality of Life instrument: Reliability and validity of the Youth Form
    Smita Bhatia
    Division of Pediatric Oncology, City of Hope National Medical Center, Duarte, California, USA
    J Pediatr 145:39-46. 2004
    ..We developed the Minneapolis-Manchester Quality of Life-Youth Form (MMQL-YF) as a standardized patient self-report instrument designed to assess HRQoL in childhood cancer survivors between the ages of 8 and 12 years...
  82. ncbi request reprint Late-effects among survivors of leukaemia and lymphoma during childhood and adolescence
    Leslie L Robison
    Division of Pediatric Epidemiology and Clinical Research, University of Minnesota Cancer Center, Minneapolis, MN, USA
    Br J Haematol 122:345-59. 2003
  83. ncbi request reprint Study design and cohort characteristics of the Childhood Cancer Survivor Study: a multi-institutional collaborative project
    Leslie L Robison
    Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota
    Med Pediatr Oncol 38:229-39. 2002
    ..To facilitate such research, a multi-institutional consortium established the Childhood Cancer Survivor Study (CCSS), a large, diverse, and well-characterized cohort of 5-year survivors of childhood and adolescent cancer...
  84. ncbi request reprint Birth characteristics, maternal reproductive history, hormone use during pregnancy, and risk of childhood acute lymphocytic leukemia by immunophenotype (United States)
    Shu Xiao Ou
    Department of Pediatrics, University of Minnesota, Minneapolis, USA
    Cancer Causes Control 13:15-25. 2002
    ..To investigate the associations of birth characteristics and maternal reproductive factors with risk of childhood acute lymphoblastic leukemia (ALL) by immunophenotypic subtypes...
  85. ncbi request reprint XRCC1 and glutathione-S-transferase gene polymorphisms and susceptibility to radiotherapy-related malignancies in survivors of Hodgkin disease
    Ann C Mertens
    Division of Pediatric Epidemiology and Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis 55455, USA
    Cancer 101:1463-72. 2004
    ..Survivors of Hodgkin disease (HD), in particular, have been shown to be at high risk of subsequent malignancy, the occurrence of which has been associated strongly with exposure to radiotherapy...
  86. ncbi request reprint High risk of subsequent neoplasms continues with extended follow-up of childhood Hodgkin's disease: report from the Late Effects Study Group
    Smita Bhatia
    City of Hope National Medical Center, 1500 E Duarte Rd, Duarte, CA 91010 3000, USA
    J Clin Oncol 21:4386-94. 2003
    ..We describe the pattern and incidence of subsequent neoplasms (SNs) occurring with extended follow-up...
  87. ncbi request reprint Characteristics of childhood cancer survivors predicted their successful tracing
    Ann C Mertens
    Department of Pediatrics Epidemiology and Clinical Research, University of Minnesota Medical School and Cancer Center, 420 Delaware Street, SE, Minneapolis, MN 55455, USA
    J Clin Epidemiol 57:933-44. 2004
    ..We evaluated the characteristics of those requiring tracing and factors that influenced tracing success...
  88. ncbi request reprint Psychological outcomes in long-term survivors of childhood brain cancer: a report from the childhood cancer survivor study
    Brad J Zebrack
    University of Southern California School of Social Work, 669 W 34th St, Los Angeles, CA 90089 0411, USA
    J Clin Oncol 22:999-1006. 2004
    ..To evaluate and compare psychological outcomes in long-term survivors of pediatric brain cancer and siblings of childhood cancer survivors, and to identify significant correlates of psychological distress...
  89. ncbi request reprint Low incidence of second neoplasms among children diagnosed with acute lymphoblastic leukemia after 1983
    Smita Bhatia
    City of Hope National Medical Center, Duarte, CA, USA group org
    Blood 99:4257-64. 2002
    ..Follow-up of this large cohort that was treated with contemporary risk-based therapy showed that the incidence of second neoplasms remains low after diagnosis of childhood ALL...
  90. ncbi request reprint Genetic effects of radiotherapy for childhood cancer
    John D Boice
    International Epidemiology Institute, 1455 Research Blvd Ste 550, Rockville, MD 20850, USA
    Health Phys 85:65-80. 2003
    ....
  91. ncbi request reprint Education, employment, insurance, and marital status among 694 survivors of pediatric lower extremity bone tumors: a report from the childhood cancer survivor study
    Rajaram Nagarajan
    Division of Pediatric Epidemiology and Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Cancer 97:2554-64. 2003
    ..The authors described psychosocial outcomes (education, employment, health insurance, and marriage) for survivors of pediatric lower extremity bone tumors...
  92. ncbi request reprint A methodological issue in the analysis of second-primary cancer incidence in long-term survivors of childhood cancers
    Yutaka Yasui
    Cancer Research Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Am J Epidemiol 158:1108-13. 2003
    ..These showed appreciable differences in the analytical results by not accounting for the natural age-associated increase of risk, illustrating a significant impact of this methodological issue on study conclusions...
  93. ncbi request reprint Trends in leukemia incidence and survival in the United States (1973-1998)
    Yang Xie
    Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Cancer 97:2229-35. 2003
    ..Although the overall incidence of leukemia has been declining in the United States, recent reports suggest that incidence rates may be increasing for certain age and racial groups...
  94. ncbi request reprint Utilization of special education services and educational attainment among long-term survivors of childhood cancer: a report from the Childhood Cancer Survivor Study
    Pauline A Mitby
    Department of Pediatrics, University of Minnesota Medical School and Cancer Center, Minneapolis, Minnesota
    Cancer 97:1115-26. 2003
    ..The objective of the current report was to compare the self-reported rates of special education (SE) and educational attainment among specific groups of childhood cancer survivors and a random sample of sibling controls...
  95. ncbi request reprint Pregnancy outcome of partners of male survivors of childhood cancer: a report from the Childhood Cancer Survivor Study
    Daniel M Green
    Department of Pediatrics, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
    J Clin Oncol 21:716-21. 2003
    ..This study was undertaken to determine the effect, if any, on pregnancy loss, live births, and birthweight of treatment for cancer diagnosed during childhood or adolescence...
  96. ncbi request reprint Pulmonary complications in survivors of childhood and adolescent cancer. A report from the Childhood Cancer Survivor Study
    Ann C Mertens
    Department of Pediatrics, University of Minnesota Medical School and Cancer Center, Minneapolis, Minnesota, USA
    Cancer 95:2431-41. 2002
    ..Previous studies have shown that exposure to chemotherapy and/or radiation can compromise pulmonary function in these survivors of childhood cancer...
  97. ncbi request reprint Pregnancy outcome of female survivors of childhood cancer: a report from the Childhood Cancer Survivor Study
    Daniel M Green
    Department of Pediatrics, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
    Am J Obstet Gynecol 187:1070-80. 2002
    ..This study was undertaken to determine the effect, if any, of prior treatment with radiation therapy or chemotherapy for cancer diagnosed during childhood or adolescence on pregnancy loss, live births, and birth weight...
  98. ncbi request reprint Risk of disease recurrence and second neoplasms in survivors of childhood cancer treated with growth hormone: a report from the Childhood Cancer Survivor Study
    Charles A Sklar
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    J Clin Endocrinol Metab 87:3136-41. 2002
    ..The increased number of SN, particularly in survivors of acute leukemia, is of concern, but the data need to be interpreted with caution given the small number of events...
  99. ncbi request reprint Psychological outcomes in long-term survivors of childhood leukemia, Hodgkin's disease, and non-Hodgkin's lymphoma: a report from the Childhood Cancer Survivor Study
    Brad J Zebrack
    Department of Pediatrics, University of California Los Angeles, School of Medicine, Los Angeles, California, USA
    Pediatrics 110:42-52. 2002
    ..To evaluate and compare psychological outcomes in long-term survivors of pediatric leukemia, Hodgkin's disease, and non-Hodgkin's lymphoma and sibling controls...
  100. ncbi request reprint Factors that affect final height and change in height standard deviation scores in survivors of childhood cancer treated with growth hormone: a report from the childhood cancer survivor study
    Carrie M Brownstein
    Memorial Sloan Kettering Cancer Center, Department of Pediatrics, 1275 York Avenue, New York, New York 10021, USA
    J Clin Endocrinol Metab 89:4422-7. 2004
    ....
  101. ncbi request reprint Development of risk-based guidelines for pediatric cancer survivors: the Children's Oncology Group Long-Term Follow-Up Guidelines from the Children's Oncology Group Late Effects Committee and Nursing Discipline
    Wendy Landier
    Division of Pediatrics, City of Hope Comprehensive Cancer Center, Duarte, CA, USA
    J Clin Oncol 22:4979-90. 2004
    ..The Guidelines, and related Health Links, can be downloaded in their entirety at www.survivorshipguidelines.org...

Research Grants5

  1. CANCER EPIDEMIOLOGY
    Leslie Robison; Fiscal Year: 2002
    ..Extensive data bases are available to trainees as well as current studies. Finally, the University has recently established a new Cancer Center with a strong program in cancer prevention and etiology. ..
  2. CHILDHOOD CANCER SURVIVOR STUDY
    Leslie Robison; Fiscal Year: 2005
    ..abstract_text> ..
  3. CHILDHOOD CANCER SURVIVOR STUDY
    Leslie Robison; Fiscal Year: 2007
    ..CCSS provides a dynamic framework and resource to investigate current and future questions among childhood cancer survivors. ..