Research Topics
Genomes and Genes
| D S RiceSummaryAffiliation: St. Jude Children's Research Hospital Country: USA Publications
| Collaborators |
Detail Information
Publications
Role of the reelin signaling pathway in central nervous system developmentD S Rice
Department of Developmental Neurobiology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
Annu Rev Neurosci 24:1005-39. 2001..Recent studies have also suggested a role for the Reelin pathway in axonal branching, synaptogenesis, and pathology underlying neurodegeneration...- Mutant mice with scrambled brains: understanding the signaling pathways that control cell positioning in the CNSD S Rice
Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA
Genes Dev 13:2758-73. 1999 - The reelin pathway modulates the structure and function of retinal synaptic circuitryD S Rice
Department of Developmental Neurobiology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
Neuron 31:929-41. 2001..These results imply that, in addition to its essential role during neuronal migration, the Reelin pathway contributes to the formation of neuronal circuits in the central nervous system... - Disabled-1 acts downstream of Reelin in a signaling pathway that controls laminar organization in the mammalian brainD S Rice
Department of Developmental Neurobiology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
Development 125:3719-29. 1998..This suggests that Dab1 accumulates in the absence of a Reln-evoked signal. Taken together, these results indicate that Dab1 functions downstream of Reln in a signaling pathway that controls cell positioning in the developing brain... - Reelin is a ligand for lipoprotein receptorsG D'ARCANGELO
Department of Developmental Neurobiology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
Neuron 24:471-9. 1999..In dissociated neurons, apoE reduces the level of Reelin-induced tyrosine phosphorylation of Dab1. These data suggest that Reelin directs neuronal migration by binding to VLDLR and ApoER2... - Disabled-1 interacts with a novel developmentally regulated protocadherinR Homayouni
Department of Developmental Neurobiology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
Biochem Biophys Res Commun 289:539-47. 2001..Our results indicate that mPcdh18 participates in signaling pathways involving PTB-containing proteins and suggest that it may play a role during brain development... - Disabled-1 is expressed in type AII amacrine cells in the mouse retinaD S Rice
Department of Developmental Neurobiology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
J Comp Neurol 424:327-38. 2000..This raises the possibility that the Reelin/Dab1 signaling pathway contributes to formation of intraretinal circuitry in the neural retina... - The Lnx family proteins function as molecular scaffolds for Numb family proteinsD S Rice
Department of Developmental Neurobiology, Saint Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
Mol Cell Neurosci 18:525-40. 2001..Therefore, our findings suggest that Lnx proteins may serve as molecular scaffolds that localize unrelated, interacting proteins, such as Numb, to specific subcellular sites... - Disabled-1 binds to the cytoplasmic domain of amyloid precursor-like protein 1R Homayouni
Department of Developmental Neurobiology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
J Neurosci 19:7507-15. 1999..Dab1 and APLP1 are expressed in similar cell populations in developing and adult brain tissue. These results suggest that Dab1 may function, at least in part, through association with APLP1 in the brain... - Scrambler and yotari disrupt the disabled gene and produce a reeler-like phenotype in miceM Sheldon
Department of Developmental Neurobiology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
Nature 389:730-3. 1997..The similar phenotypes of reeler, scrambler, yotari and mdab1 null mice indicate that Reelin and mDab1 function as signalling molecules that regulate cell positioning in the developing brain... - Extrinsic modulation of retinal ganglion cell projections: analysis of the albino mutation in pigmentation mosaic miceD S Rice
Department of Developmental Neurobiology, St Jude Children s Research Hospital, Memphis, Tennessee, 38105, USA
Dev Biol 216:41-56. 1999..These studies demonstrate that the albino mutation acts indirectly upon retinal ganglion cells, which in turn respond by making axonal guidance errors at the optic chiasm... - Purification of Purkinje cells by fluorescence-activated cell sorting from transgenic mice that express green fluorescent proteinM Tomomura
Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA
Eur J Neurosci 14:57-63. 2001..GFP-positive neurons will also be useful in the real-time observation of dendritic morphogenesis and axonal outgrowth during development, or after neuronal activity in vitro... 
HERF1, a novel hematopoiesis-specific RING finger protein, is required for terminal differentiation of erythroid cellsH Harada
Departments of Pathology and Laboratory Medicine, St Jude Children s Research Hospital, Memphis, Tennessee, USA
Mol Cell Biol 19:3808-15. 1999..These results suggest an important role for this protein in erythropoiesis...- Disrupted retinal development in the embryonic belly spot and tail mutant mouseQ Tang
Center for Neuroscience, University of Tennessee Memphis, 855 Monroe Avenue, Memphis, Tennessee, 38163, USA
Dev Biol 207:239-55. 1999.... - Decreased retinal ganglion cell number and misdirected axon growth associated with fissure defects in Bst/+ mutant miceD S Rice
Department of Anatomy and Neurobiology, College of Medicine, University of Tennessee, Memphis 38163, USA
Invest Ophthalmol Vis Sci 38:2112-24. 1997..In this article, the authors present adult and developmental studies on the retinal phenotype in Bst/+ mice...