Bassen I Razzouk

Summary

Affiliation: St. Jude Children's Research Hospital
Country: USA

Publications

  1. ncbi request reprint Minimally invasive radiological diagnosis of pediatric hematological malignancies
    Bassen I Razzouk
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    Pediatr Radiol 32:652. 2002
  2. ncbi request reprint Obesity in survivors of childhood acute lymphoblastic leukemia and lymphoma
    Bassem I Razzouk
    Department of Hematology Oncology, St Jude Children s Research Hospital and the University of Tennessee Health Science Center, Memphis, TN 38105 2794, USA
    J Clin Oncol 25:1183-9. 2007
  3. ncbi request reprint Double-blind, placebo-controlled study of quality of life, hematologic end points, and safety of weekly epoetin alfa in children with cancer receiving myelosuppressive chemotherapy
    Bassem I Razzouk
    St Jude Children s Research Hospital, Memphis, TN, USA
    J Clin Oncol 24:3583-9. 2006
  4. ncbi request reprint Impact of age on outcome of pediatric acute myeloid leukemia: a report from 2 institutions
    Bassem I Razzouk
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, and Department of Leukemia, University of Texas M D Anderson Cancer Center, Houston, USA
    Cancer 106:2495-502. 2006
  5. ncbi request reprint Viridans streptococcal sepsis: clinical features and complications in childhood acute myeloid leukemia
    Yasuhiro Okamoto
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    J Pediatr Hematol Oncol 25:696-703. 2003
  6. ncbi request reprint Clinical significance of residual disease during treatment in childhood acute myeloid leukaemia
    Elaine Coustan-Smith
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN, USA
    Br J Haematol 123:243-52. 2003
  7. ncbi request reprint Prognostic significance of myeloperoxidase expression in childhood acute myeloid leukemia
    Jessica R Roberson
    Department of Hematology Oncology, St Jude Children s Research Hospital, and the University of Tennessee College of Medicine, Memphis, Tennessee, USA
    Pediatr Blood Cancer 50:542-8. 2008
  8. ncbi request reprint Effect of race on outcome of white and black children with acute myeloid leukemia: the St. Jude experience
    Jeffrey E Rubnitz
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Pediatr Blood Cancer 48:10-5. 2007
  9. pmc Prognostic significance of CD20 expression in childhood B-cell precursor acute lymphoblastic leukemia
    Sima Jeha
    Department of Hematology Oncology, St Jude Children s Research Hospital, 332 N Lauderdale St, Memphis, TN 38105, USA
    Blood 108:3302-4. 2006
  10. ncbi request reprint Prognostic factors and outcome of recurrence in childhood acute myeloid leukemia
    Jeffrey E Rubnitz
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Cancer 109:157-63. 2007

Detail Information

Publications42

  1. ncbi request reprint Minimally invasive radiological diagnosis of pediatric hematological malignancies
    Bassen I Razzouk
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    Pediatr Radiol 32:652. 2002
  2. ncbi request reprint Obesity in survivors of childhood acute lymphoblastic leukemia and lymphoma
    Bassem I Razzouk
    Department of Hematology Oncology, St Jude Children s Research Hospital and the University of Tennessee Health Science Center, Memphis, TN 38105 2794, USA
    J Clin Oncol 25:1183-9. 2007
    ....
  3. ncbi request reprint Double-blind, placebo-controlled study of quality of life, hematologic end points, and safety of weekly epoetin alfa in children with cancer receiving myelosuppressive chemotherapy
    Bassem I Razzouk
    St Jude Children s Research Hospital, Memphis, TN, USA
    J Clin Oncol 24:3583-9. 2006
    ..To evaluate the effects of once-weekly epoetin alfa (EPO) on health-related quality of life (HRQOL), hemoglobin (Hb), transfusions, and tolerability in children with cancer...
  4. ncbi request reprint Impact of age on outcome of pediatric acute myeloid leukemia: a report from 2 institutions
    Bassem I Razzouk
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, and Department of Leukemia, University of Texas M D Anderson Cancer Center, Houston, USA
    Cancer 106:2495-502. 2006
    ..The prognostic significance of age among pediatric patients with acute myeloid leukemia (AML) was investigated...
  5. ncbi request reprint Viridans streptococcal sepsis: clinical features and complications in childhood acute myeloid leukemia
    Yasuhiro Okamoto
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    J Pediatr Hematol Oncol 25:696-703. 2003
    ..Viridans streptococci (VS) are a primary cause of infection and pneumonia in patients with neutropenia. The authors determined the incidence, clinical features, and complications of VS sepsis in children receiving chemotherapy for AML...
  6. ncbi request reprint Clinical significance of residual disease during treatment in childhood acute myeloid leukaemia
    Elaine Coustan-Smith
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN, USA
    Br J Haematol 123:243-52. 2003
    ..022); overt recurrence of AML within the subsequent 6 months was significantly more likely in the former group. The assay described here holds promise for guiding the choice of post-remission treatment options in children with AML...
  7. ncbi request reprint Prognostic significance of myeloperoxidase expression in childhood acute myeloid leukemia
    Jessica R Roberson
    Department of Hematology Oncology, St Jude Children s Research Hospital, and the University of Tennessee College of Medicine, Memphis, Tennessee, USA
    Pediatr Blood Cancer 50:542-8. 2008
    ..The percentage of myeloperoxidase (MPO)-positive blast cells is associated with prognosis in adult acute myeloid leukemia (AML), but this association is unsubstantiated in pediatric AML...
  8. ncbi request reprint Effect of race on outcome of white and black children with acute myeloid leukemia: the St. Jude experience
    Jeffrey E Rubnitz
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Pediatr Blood Cancer 48:10-5. 2007
    ..The association between race and outcome of treatment for childhood acute myeloid leukemia (AML) has not been adequately studied...
  9. pmc Prognostic significance of CD20 expression in childhood B-cell precursor acute lymphoblastic leukemia
    Sima Jeha
    Department of Hematology Oncology, St Jude Children s Research Hospital, 332 N Lauderdale St, Memphis, TN 38105, USA
    Blood 108:3302-4. 2006
    ..9% versus 78% +/- 3.1% (P = .08). These data suggest that CD20 expression is not associated with inferior outcome in pediatric patients treated with contemporary regimens...
  10. ncbi request reprint Prognostic factors and outcome of recurrence in childhood acute myeloid leukemia
    Jeffrey E Rubnitz
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Cancer 109:157-63. 2007
    ..Outcome after recurrence of childhood acute myeloid leukemia (AML) is poor. We performed this study to identify prognostic factors for recurrence and for survival after recurrence of AML...
  11. ncbi request reprint Cumulative incidence of secondary neoplasms as a first event after childhood acute lymphoblastic leukemia
    Nobuko Hijiya
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    JAMA 297:1207-15. 2007
    ..Little is known about the incidence of secondary neoplasms after 15 to 20 years in children and adolescents who were treated for acute lymphoblastic leukemia...
  12. ncbi request reprint Clinical field testing of an enhanced-activity intervention in hospitalized children with cancer
    Pamela S Hinds
    Division of Nursing Research, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    J Pain Symptom Manage 33:686-97. 2007
    ..Our findings identify design and statistical considerations for a future effectiveness study of the EPA intervention in hospitalized pediatric oncology patients...
  13. ncbi request reprint Nocturnal awakenings, sleep environment interruptions, and fatigue in hospitalized children with cancer
    Pamela S Hinds
    Division of Nursing Research, St Jude Children s Research Hospital, Memphis, TN, USA
    Oncol Nurs Forum 34:393-402. 2007
    ....
  14. pmc BK virus-induced tubulointerstitial nephritis in a child with acute lymphoblastic leukemia
    Hiroto Inaba
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    J Pediatr 151:215-7. 2007
    ..Careful administration of chemotherapy and anti-viral therapy prevented further damage. This diagnosis should be considered in children who experience renal dysfunction during cancer treatment...
  15. ncbi request reprint Creating a palliative and end-of-life program in a cure-oriented pediatric setting: the zig-zag method
    JoAnn Harper
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    J Pediatr Oncol Nurs 24:246-54. 2007
    ..They conclude that establishing a state-of-the-art palliative and EoL program in a cure-oriented pediatric setting is achievable via consensus building and recruitment of diverse institutional resources...
  16. pmc Randomized trial of 2 dosages of prophylactic granulocyte-colony-stimulating factor after induction chemotherapy in pediatric acute myeloid leukemia
    Hiroto Inaba
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Cancer 117:1313-20. 2011
    ..However, the optimal G-CSF dosage for patients with AML has not been determined. To the authors' knowledge, G-CSF dosages have not been compared in a randomized AML study...
  17. doi request reprint Clinical and biologic features and treatment outcome of children with newly diagnosed acute myeloid leukemia and hyperleukocytosis
    Hiroto Inaba
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Cancer 113:522-9. 2008
    ..To the authors' knowledge, no recently published study has evaluated the management and clinical course in this regard, especially in relation to pediatric patients...
  18. pmc Acute mixed lineage leukemia in children: the experience of St Jude Children's Research Hospital
    Jeffrey E Rubnitz
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    Blood 113:5083-9. 2009
    ..We also suggest that hematopoietic stem cell transplantation is often not required for cure of these patients...
  19. pmc Combination of cladribine plus topotecan for recurrent or refractory pediatric acute myeloid leukemia
    Hiroto Inaba
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Cancer 116:98-105. 2010
    ..The prognosis after recurrence of pediatric acute myeloid leukemia (AML) is poor, and effective salvage regimens are urgently needed...
  20. pmc Minimal residual disease-directed therapy for childhood acute myeloid leukaemia: results of the AML02 multicentre trial
    Jeffrey E Rubnitz
    Department of Oncology, St Jude Children s Research Hospital and the University of Tennessee Health Science Center, Memphis, TN 38105 2794, USA
    Lancet Oncol 11:543-52. 2010
    ....
  21. ncbi request reprint Phase II study of clofarabine in pediatric patients with refractory or relapsed acute lymphoblastic leukemia
    Sima Jeha
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Clin Oncol 24:1917-23. 2006
    ..To evaluate the efficacy and safety of clofarabine, a novel deoxyadenosine analog, in pediatric patients with refractory or relapsed acute lymphoblastic leukemia (ALL)...
  22. ncbi request reprint Phase II trial of cladribine and cytarabine in relapsed or refractory myeloid malignancies
    Jeffrey E Rubnitz
    Department of Hematology Oncology, St Jude Children s Research Hospital, Mail Stop 260, 332 N Lauderdale Street, Memphis, TN 38105 2794, USA
    Leuk Res 28:349-52. 2004
    ..Despite the efficacy of the cladribine and cytarabine regimen in treating newly diagnosed acute myeloid leukemia (AML) in a previously reported study, the combination was not effective for relapsed or refractory childhood AML...
  23. ncbi request reprint Results of therapy for acute lymphoblastic leukemia in black and white children
    Ching Hon Pui
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    JAMA 290:2001-7. 2003
    ..Treatment results for acute lymphoblastic leukemia (ALL) clearly have improved over the past decade, but black children have not fared as well as white children in large national trials...
  24. ncbi request reprint Pharmacokinetics of 2-chlorodeoxyadenosine in a child undergoing hemofiltration and hemodialysis for acute renal failure
    Kristine R Crews
    Department of Pharmaceutical Sciences, St Jude Children s Research Hospital, 332 N Lauderdale, Memphis, TN 38105 2794, USA
    J Pediatr Hematol Oncol 24:677-80. 2002
    ..More experience in the administration of 2-CdA to patients with renal insufficiency will be necessary to determine the need for dosage adjustment...
  25. ncbi request reprint Improved outcome for children with acute lymphoblastic leukemia: results of Total Therapy Study XIIIB at St Jude Children's Research Hospital
    Ching Hon Pui
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    Blood 104:2690-6. 2004
    ..01% or more at the end of the 6-week remission induction phase. Our results suggest the efficacy of early intensification of intrathecal chemotherapy and provide the basis for studies omitting cranial irradiation altogether...
  26. ncbi request reprint Severe cardiopulmonary complications consistent with systemic inflammatory response syndrome caused by leukemia cell lysis in childhood acute myelomonocytic or monocytic leukemia
    Nobuko Hijiya
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Pediatr Blood Cancer 44:63-9. 2005
    ..Life-threatening pulmonary complications that coincide with cell lysis during early chemotherapy and that mimic systemic inflammatory response syndrome (SIRS) have been reported in patients with acute myeloid leukemia (AML)...
  27. ncbi request reprint Death during induction therapy and first remission of acute leukemia in childhood: the St. Jude experience
    Jeffrey E Rubnitz
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Cancer 101:1677-84. 2004
    ..Despite improvements in supportive care, death due to treatment toxicity remains a significant problem for children treated for acute leukemia...
  28. ncbi request reprint Favorable impact of the t(9;11) in childhood acute myeloid leukemia
    Jeffrey E Rubnitz
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    J Clin Oncol 20:2302-9. 2002
    ..To determine the impact of MLL rearrangements on the outcome of children with acute myeloid leukemia (AML)...
  29. ncbi request reprint Risk factors for traumatic and bloody lumbar puncture in children with acute lymphoblastic leukemia
    Scott C Howard
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN, USA
    JAMA 288:2001-7. 2002
    ..Traumatic or bloody lumbar puncture (LP) reduces the diagnostic value of the procedure and may worsen the outcome of patients with acute lymphoblastic leukemia (ALL). Little is known about the risk factors for traumatic and bloody LP...
  30. pmc Body mass index does not influence pharmacokinetics or outcome of treatment in children with acute lymphoblastic leukemia
    Nobuko Hijiya
    Department of Oncology, St Jude Children s Research Hospital, 332 North Lauderdale St, Memphis, TN 38105 2794, USA
    Blood 108:3997-4002. 2006
    ..Further, the systemic clearance of methotrexate, teniposide, etoposide, and cytarabine did not differ with BMI (P > .3). We conclude that BMI does not affect the outcome or toxicity of chemotherapy in this patient population with ALL...
  31. ncbi request reprint Interim comparison of a continuous infusion versus a short daily infusion of cytarabine given in combination with cladribine for pediatric acute myeloid leukemia
    Kristine R Crews
    Department of Pharmaceutical Sciences, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Clin Oncol 20:4217-24. 2002
    ....
  32. ncbi request reprint Prognostic importance of measuring early clearance of leukemic cells by flow cytometry in childhood acute lymphoblastic leukemia
    Elaine Coustan-Smith
    Department of Hematology Oncology, St Jude Children s Research Hospital and the University of Tennessee, Memphis, TN 38105, USA
    Blood 100:52-8. 2002
    ..Thus, approximately half of the children with ALL achieve profound clearance of leukemic cells after 2 to 3 weeks of remission-induction chemotherapy, and these patients have an excellent treatment outcome...
  33. ncbi request reprint Risk of adverse events after completion of therapy for childhood acute lymphoblastic leukemia
    Ching Hon Pui
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    J Clin Oncol 23:7936-41. 2005
    ..Our goal was to use the information to further refine therapy and advance cure rates...
  34. ncbi request reprint Pathophysiology-directed therapy for acute hypoxemic respiratory failure in acute myeloid leukemia with hyperleukocytosis
    Jeffrey E Schmidt
    Division of Critical Care Medicine, St Jude Children s Research Hospital, 332 N Lauderdale, MS 323, Memphis, TN 38105, U S A
    J Pediatr Hematol Oncol 25:569-71. 2003
    ..The patient was successfully extubated. Patients with myelomonocytic leukemias are at risk for early death due to pulmonary complications. The use of adjuvant therapies directed by specific pathophysiology might decrease this risk...
  35. ncbi request reprint Pharmacokinetics and pharmacodynamics of intravenous epoetin alfa in children with cancer
    Burgess B Freeman
    Department of Pharmaceutical Sciences, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Pediatr Blood Cancer 47:572-9. 2006
    ..Epoetin alfa (EPO, PROCRIT) pharmacokinetics and pharmacodynamics were evaluated in children with malignant solid tumors receiving chemotherapy...
  36. ncbi request reprint Typhlitis in childhood cancer
    M Beth McCarville
    Division of Diagnostic Imaging, Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA jude org
    Cancer 104:380-7. 2005
    ..The authors investigated the demographic, clinical, and imaging (ultrasonography and computed tomography [CT] scans) variables related to the diagnosis, risk, and outcome of typhlitis...
  37. ncbi request reprint Cancer-related deaths in children and adolescents
    Glenna Bradshaw
    Baptist Memorial Hospital East, Memphis, Tennessee, USA
    J Palliat Med 8:86-95. 2005
    ..To add to the data regarding the quality of care given to dying children and their families...
  38. doi request reprint Prophylactic antibiotics reduce morbidity due to septicemia during intensive treatment for pediatric acute myeloid leukemia
    Beth Kurt
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Cancer 113:376-82. 2008
    ..The aim of this study was to determine whether antibiotic prophylaxis during periods of neutropenia reduced streptococcal (S. viridans) sepsis and overall bacterial sepsis...
  39. pmc Phase 1 trial and pharmacokinetic study of arsenic trioxide in children and adolescents with refractory or relapsed acute leukemia, including acute promyelocytic leukemia or lymphoma
    Elizabeth Fox
    Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA
    Blood 111:566-73. 2008
    ..15 mg/kg per day. The response rate in children with relapsed APL is similar to the response rate in adults. This trial was registered as #NCT00020111 at www.ClinicalTrials.gov...
  40. ncbi request reprint Clinical presentation and treatment outcome of children with Burkitt lymphoma in Lebanon: a single institution's experience
    Samar A Muwakkit
    Children s Cancer Center of Lebanon, American University of Beirut, Lebanon
    J Pediatr Hematol Oncol 26:749-53. 2004
    ..If confirmed in a larger series of patients, this study could have a major impact on the treatment of Burkitt lymphoma in Lebanon and other countries with limited resources...
  41. ncbi request reprint Use of peripheral blood instead of bone marrow to monitor residual disease in children with acute lymphoblastic leukemia
    Elaine Coustan-Smith
    Departments of Hematology Oncology, Biostatistics, and Pathology, St Jude Children s Research Hospital, and the University of Tennessee, Memphis TN 38105 2794, USA
    Blood 100:2399-402. 2002
    ..007). These results indicate that peripheral blood may be used to monitor MRD in patients with T-lineage ALL and that peripheral blood MRD may provide strong prognostic information in patients with B-lineage ALL...
  42. ncbi request reprint Reinduction of relapsed acute promyelocytic leukemia with ATRA and low dose antimetabolite-based chemotherapy
    Christopher C Dvorak
    Division of Pediatric Hematology, Oncology, and Bone Marrow Transplantation, Stanford University School of Medicine, Palo Alto, California 94304, USA
    Pediatr Blood Cancer 48:582-5. 2007
    ..These cases demonstrate that there is a role for ATRA plus differentiating chemotherapy other than arsenic trioxide in the treatment of relapsed APML...