Stephane Pelletier

Summary

Affiliation: St. Jude Children's Research Hospital
Country: USA

Publications

  1. doi request reprint Mouse genome engineering via CRISPR-Cas9 for study of immune function
    Stephane Pelletier
    Department of Immunology, St Jude Children s Hospital, Memphis, TN 38103, USA Electronic address
    Immunity 42:18-27. 2015
  2. doi request reprint An early onset progressive motor neuron disorder in Scyl1-deficient mice is associated with mislocalization of TDP-43
    Stephane Pelletier
    Department of Biochemistry, Advanced Histology Core, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    J Neurosci 32:16560-73. 2012
  3. pmc Jak2 FERM domain interaction with the erythropoietin receptor regulates Jak2 kinase activity
    Megumi Funakoshi-Tago
    Department of Biochemistry, D4013, St Jude Children s Research Hospital, 332 North Lauderdale, Memphis, Tennessee 38105, USA
    Mol Cell Biol 28:1792-801. 2008
  4. pmc Receptor specific downregulation of cytokine signaling by autophosphorylation in the FERM domain of Jak2
    Megumi Funakoshi-Tago
    Department of Biochemistry, St Jude Children s Research Hospital, Memphis, TN 3810, USA
    EMBO J 25:4763-72. 2006
  5. pmc Characterization of a family of novel cysteine- serine-rich nuclear proteins (CSRNP)
    Sebastien Gingras
    Department of Biochemistry, St Jude Children s Research Hospital, Memphis, Tennessee, United States of America
    PLoS ONE 2:e808. 2007
  6. pmc Two domains of the erythropoietin receptor are sufficient for Jak2 binding/activation and function
    Stephane Pelletier
    Department of Biochemistry, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Mol Cell Biol 26:8527-38. 2006
  7. pmc Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration
    Rhonda M Perciavalle
    Department of Biochemistry, St Jude Children s Research Hospital, 262 Danny Thomas Place, Memphis, Tennessee 38105, USA
    Nat Cell Biol 14:575-83. 2012

Collaborators

Detail Information

Publications7

  1. doi request reprint Mouse genome engineering via CRISPR-Cas9 for study of immune function
    Stephane Pelletier
    Department of Immunology, St Jude Children s Hospital, Memphis, TN 38103, USA Electronic address
    Immunity 42:18-27. 2015
    ..Here, we discuss the practical advantages of the CRISPR-Cas9 system over conventional and other nuclease-based targeting technologies and provide suggestions for the use of this technology to address immunological questions...
  2. doi request reprint An early onset progressive motor neuron disorder in Scyl1-deficient mice is associated with mislocalization of TDP-43
    Stephane Pelletier
    Department of Biochemistry, Advanced Histology Core, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    J Neurosci 32:16560-73. 2012
    ..Together, our results identify SCYL1 as a key regulator of motor neuron survival, and Scyl1(-/-) mice share pathological features with many human neurodegenerative conditions...
  3. pmc Jak2 FERM domain interaction with the erythropoietin receptor regulates Jak2 kinase activity
    Megumi Funakoshi-Tago
    Department of Biochemistry, D4013, St Jude Children s Research Hospital, 332 North Lauderdale, Memphis, Tennessee 38105, USA
    Mol Cell Biol 28:1792-801. 2008
    ....
  4. pmc Receptor specific downregulation of cytokine signaling by autophosphorylation in the FERM domain of Jak2
    Megumi Funakoshi-Tago
    Department of Biochemistry, St Jude Children s Research Hospital, Memphis, TN 3810, USA
    EMBO J 25:4763-72. 2006
    ..This regulation occurs with the receptors for Epo, thrombopoietin and growth hormone but not with the receptor for interferon-gamma...
  5. pmc Characterization of a family of novel cysteine- serine-rich nuclear proteins (CSRNP)
    Sebastien Gingras
    Department of Biochemistry, St Jude Children s Research Hospital, Memphis, Tennessee, United States of America
    PLoS ONE 2:e808. 2007
    ..However, combined deficiencies cause partial neonatal lethality suggesting that the genes have redundant functions...
  6. pmc Two domains of the erythropoietin receptor are sufficient for Jak2 binding/activation and function
    Stephane Pelletier
    Department of Biochemistry, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Mol Cell Biol 26:8527-38. 2006
    ..Collectively, the results suggest that Jak2 is the sole direct signaling molecule downstream of EpoR required for biological activity...
  7. pmc Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration
    Rhonda M Perciavalle
    Department of Biochemistry, St Jude Children s Research Hospital, 262 Danny Thomas Place, Memphis, Tennessee 38105, USA
    Nat Cell Biol 14:575-83. 2012
    ..Our results provide insight into how the surprisingly diverse salutary functions of MCL-1 may control the survival of both normal and cancer cells...