Jonas A Nilsson

Summary

Affiliation: St. Jude Children's Research Hospital
Country: USA

Publications

  1. ncbi request reprint Mnt: master regulator of the Max network
    Jonas A Nilsson
    Department of Biochemistry, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Cell Cycle 3:588-90. 2004
  2. ncbi request reprint Id2 is dispensable for myc-induced lymphomagenesis
    Jonas A Nilsson
    Department of Biochemistry and the Animal Resource Center, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Cancer Res 64:7296-301. 2004
  3. pmc Skp2 directs Myc-mediated suppression of p27Kip1 yet has modest effects on Myc-driven lymphomagenesis
    Jennifer B Old
    Department of Biochemistry, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Mol Cancer Res 8:353-62. 2010
  4. pmc Myc targets Cks1 to provoke the suppression of p27Kip1, proliferation and lymphomagenesis
    Ulrich B Keller
    Department of Biochemistry, St Jude Children s Research Hospital, Memphis, TN, USA
    EMBO J 26:2562-74. 2007
  5. ncbi request reprint Targeting ornithine decarboxylase in Myc-induced lymphomagenesis prevents tumor formation
    Jonas A Nilsson
    Department of Biochemistry, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Cancer Cell 7:433-44. 2005
  6. pmc Selection against PUMA gene expression in Myc-driven B-cell lymphomagenesis
    Sean P Garrison
    Department of Biochemistry, St Jude Children s Research Hospital, 332 N Lauderdale, Memphis, TN 38105, USA
    Mol Cell Biol 28:5391-402. 2008
  7. pmc Mnt loss triggers Myc transcription targets, proliferation, apoptosis, and transformation
    Jonas A Nilsson
    Department of Biochemistry, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Mol Cell Biol 24:1560-9. 2004
  8. ncbi request reprint Nfkb 1 is dispensable for Myc-induced lymphomagenesis
    Ulrich Keller
    Department of Biochemistry, St Jude Children s Research Hospital, 332 N Lauderdale, Memphis, TN 38105, USA
    Oncogene 24:6231-40. 2005
  9. pmc The novel ETS factor TEL2 cooperates with Myc in B lymphomagenesis
    Monica Cardone
    Department of Genetics, St Jude Children s Research Hospital, 332 North Lauderdale, Memphis, TN 38105, USA
    Mol Cell Biol 25:2395-405. 2005
  10. pmc c-Myc augments gamma irradiation-induced apoptosis by suppressing Bcl-XL
    Kirsteen H Maclean
    Department of Biochemistry, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Mol Cell Biol 23:7256-70. 2003

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Mnt: master regulator of the Max network
    Jonas A Nilsson
    Department of Biochemistry, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Cell Cycle 3:588-90. 2004
    ..These findings indicate that Myc's ability to function as an oncogene may rely, at least in part, on its ability to effectively antagonize Mnt's transrepression and tumor suppressor functions...
  2. ncbi request reprint Id2 is dispensable for myc-induced lymphomagenesis
    Jonas A Nilsson
    Department of Biochemistry and the Animal Resource Center, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Cancer Res 64:7296-301. 2004
    ..Collectively these findings argue that targeting Id2 functions may be ineffective in preventing Myc-associated malignancies...
  3. pmc Skp2 directs Myc-mediated suppression of p27Kip1 yet has modest effects on Myc-driven lymphomagenesis
    Jennifer B Old
    Department of Biochemistry, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Mol Cancer Res 8:353-62. 2010
    ..Collectively, these findings suggest that Cks1 targets, in addition to p27(Kip1), are critical for Myc-driven proliferation and tumorigenesis...
  4. pmc Myc targets Cks1 to provoke the suppression of p27Kip1, proliferation and lymphomagenesis
    Ulrich B Keller
    Department of Biochemistry, St Jude Children s Research Hospital, Memphis, TN, USA
    EMBO J 26:2562-74. 2007
    ..Therefore, Myc suppresses p27(Kip1) expression, accelerates cell proliferation and promotes tumorigenesis at least in part through its ability to selectively induce Cks1...
  5. ncbi request reprint Targeting ornithine decarboxylase in Myc-induced lymphomagenesis prevents tumor formation
    Jonas A Nilsson
    Department of Biochemistry, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Cancer Cell 7:433-44. 2005
    ..Therefore, Odc is a critical Myc transcription target that regulates checkpoints that guard against tumorigenesis and is an effective target for cancer chemoprevention...
  6. pmc Selection against PUMA gene expression in Myc-driven B-cell lymphomagenesis
    Sean P Garrison
    Department of Biochemistry, St Jude Children s Research Hospital, 332 N Lauderdale, Memphis, TN 38105, USA
    Mol Cell Biol 28:5391-402. 2008
    ..These findings establish that PUMA is silenced in human malignancies, and they suggest PUMA as a target for the development of novel chemotherapeutics...
  7. pmc Mnt loss triggers Myc transcription targets, proliferation, apoptosis, and transformation
    Jonas A Nilsson
    Department of Biochemistry, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Mol Cell Biol 24:1560-9. 2004
    ..Therefore, Mnt behaves as a tumor suppressor. These findings support a model where Mnt represses Myc target genes and Myc functions as an oncogene by relieving Mnt-mediated repression...
  8. ncbi request reprint Nfkb 1 is dispensable for Myc-induced lymphomagenesis
    Ulrich Keller
    Department of Biochemistry, St Jude Children s Research Hospital, 332 N Lauderdale, Memphis, TN 38105, USA
    Oncogene 24:6231-40. 2005
    ..Nonetheless, loss of Nfkb 1 did not appreciably affect Myc's proliferative or apoptotic responses in B cells and had no effect on lymphoma development in Emu-Myc mice. Therefore, Nfkb 1 is dispensable for Myc-induced lymphomagenesis....
  9. pmc The novel ETS factor TEL2 cooperates with Myc in B lymphomagenesis
    Monica Cardone
    Department of Genetics, St Jude Children s Research Hospital, 332 North Lauderdale, Memphis, TN 38105, USA
    Mol Cell Biol 25:2395-405. 2005
    ..Therefore, TEL2 and MYC also appear to cooperate in provoking a cadre of human B-cell malignancies...
  10. pmc c-Myc augments gamma irradiation-induced apoptosis by suppressing Bcl-XL
    Kirsteen H Maclean
    Department of Biochemistry, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Mol Cell Biol 23:7256-70. 2003
    ..Therefore, MYC may sensitize tumor cells to DNA damage by suppressing Bcl-X...
  11. ncbi request reprint Myc pathways provoking cell suicide and cancer
    Jonas A Nilsson
    Department of Biochemistry, St Jude Children s Research Hospital, 332 N Lauderdale, Memphis, TN 38105, USA
    Oncogene 22:9007-21. 2003
    ..The precise mechanism(s) by which Myc targets these pathways are largely unresolved, but we propose that they involve crosstalk and feedback regulatory loops between arbiters of cell death...
  12. pmc c-Myc is essential for vasculogenesis and angiogenesis during development and tumor progression
    Troy A Baudino
    Department of Biochemistry, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Genes Dev 16:2530-43. 2002
    ..These findings support the model wherein c-Myc promotes cell growth and transformation, as well as vascular and hematopoietic development, by functioning as a master regulator of angiogenic factors...
  13. pmc Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants
    Michael T Hemann
    Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA
    Nature 436:807-11. 2005
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