Monika L Metzger

Summary

Affiliation: St. Jude Children's Research Hospital
Country: USA

Publications

  1. doi request reprint Female reproductive health after childhood, adolescent, and young adult cancers: guidelines for the assessment and management of female reproductive complications
    Monika L Metzger
    St Jude Children s Research Hospital, Memphis, TN, USA
    J Clin Oncol 31:1239-47. 2013
  2. pmc Association between radiotherapy vs no radiotherapy based on early response to VAMP chemotherapy and survival among children with favorable-risk Hodgkin lymphoma
    Monika L Metzger
    Department of Oncology, St Jude Children s Research Hospital, and Health Sciences Center, University of Tennessee, Memphis, USA
    JAMA 307:2609-16. 2012
  3. doi request reprint Effect of race on the outcome of pediatric patients with Hodgkin's lymphoma
    Monika L Metzger
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    J Clin Oncol 26:1282-8. 2008
  4. ncbi request reprint White race as a risk factor for hypothyroidism after treatment for pediatric Hodgkin's lymphoma
    Monika L Metzger
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    J Clin Oncol 24:1516-21. 2006
  5. pmc Initial response to salvage therapy determines prognosis in relapsed pediatric Hodgkin lymphoma patients
    Monika L Metzger
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Cancer 116:4376-84. 2010
  6. ncbi request reprint Outcome of childhood acute lymphoblastic leukaemia in resource-poor countries
    Monika L Metzger
    Department of Hematology Oncology and International Outreach Program, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    Lancet 362:706-8. 2003
  7. ncbi request reprint Patterns of treatment failure in pediatric and young adult patients with Hodgkin's disease: local disease control with combined-modality therapy
    Matthew J Krasin
    Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Clin Oncol 23:8406-13. 2005
  8. pmc Improved prognosis for older adolescents with acute lymphoblastic leukemia
    Ching Hon Pui
    St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Clin Oncol 29:386-91. 2011
  9. pmc Treatment outcomes in black and white children with cancer: results from the SEER database and St Jude Children's Research Hospital, 1992 through 2007
    Ching Hon Pui
    St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Clin Oncol 30:2005-12. 2012
  10. pmc Treating childhood acute lymphoblastic leukemia without cranial irradiation
    Ching Hon Pui
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    N Engl J Med 360:2730-41. 2009

Detail Information

Publications32

  1. doi request reprint Female reproductive health after childhood, adolescent, and young adult cancers: guidelines for the assessment and management of female reproductive complications
    Monika L Metzger
    St Jude Children s Research Hospital, Memphis, TN, USA
    J Clin Oncol 31:1239-47. 2013
    ..Cancer therapy can often affect reproductive organs, leading to impaired pubertal development, hormonal regulation, fertility, and sexual function, affecting quality of life...
  2. pmc Association between radiotherapy vs no radiotherapy based on early response to VAMP chemotherapy and survival among children with favorable-risk Hodgkin lymphoma
    Monika L Metzger
    Department of Oncology, St Jude Children s Research Hospital, and Health Sciences Center, University of Tennessee, Memphis, USA
    JAMA 307:2609-16. 2012
    ..Pediatric oncologists strive for maintaining excellent cure rates while minimizing toxic effects...
  3. doi request reprint Effect of race on the outcome of pediatric patients with Hodgkin's lymphoma
    Monika L Metzger
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    J Clin Oncol 26:1282-8. 2008
    ..We examine the effects of race on clinical outcomes among children with Hodgkin's lymphoma (HL) treated with contemporary therapy at a tertiary care children's hospital...
  4. ncbi request reprint White race as a risk factor for hypothyroidism after treatment for pediatric Hodgkin's lymphoma
    Monika L Metzger
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    J Clin Oncol 24:1516-21. 2006
    ..The aim of this study was to determine whether race is an independent risk factor for hypothyroidism in survivors of pediatric Hodgkin's lymphoma...
  5. pmc Initial response to salvage therapy determines prognosis in relapsed pediatric Hodgkin lymphoma patients
    Monika L Metzger
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Cancer 116:4376-84. 2010
    ..Pediatric Hodgkin lymphoma (HL) is a highly curable disease; however, prognostic factors for the survival of patients who develop recurrent disease have not been clearly defined...
  6. ncbi request reprint Outcome of childhood acute lymphoblastic leukaemia in resource-poor countries
    Monika L Metzger
    Department of Hematology Oncology and International Outreach Program, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    Lancet 362:706-8. 2003
    ..Outcome could be substantially improved by interventions that help to prevent abandonment of therapy (such as funding for transport, satellite clinics, and support groups), and by prompt treatment of infection...
  7. ncbi request reprint Patterns of treatment failure in pediatric and young adult patients with Hodgkin's disease: local disease control with combined-modality therapy
    Matthew J Krasin
    Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Clin Oncol 23:8406-13. 2005
    ..This study defines the cumulative incidence (CI) of local failure (LF) and prognostic factors for pediatric patients treated for HD with combined-modality therapy (CMT)...
  8. pmc Improved prognosis for older adolescents with acute lymphoblastic leukemia
    Ching Hon Pui
    St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Clin Oncol 29:386-91. 2011
    ..We reviewed the outcome of older adolescents (age 15 to 18 years) treated in four consecutive Total Therapy studies to determine if recent improved treatment extended to this high-risk group...
  9. pmc Treatment outcomes in black and white children with cancer: results from the SEER database and St Jude Children's Research Hospital, 1992 through 2007
    Ching Hon Pui
    St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Clin Oncol 30:2005-12. 2012
    ..Treatment outcome for black patients with cancer has been significantly worse than for their white counterparts. We determined whether recent improved treatment had narrowed the gap in outcome between black and white pediatric patients...
  10. pmc Treating childhood acute lymphoblastic leukemia without cranial irradiation
    Ching Hon Pui
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    N Engl J Med 360:2730-41. 2009
    ..Prophylactic cranial irradiation has been a standard treatment in children with acute lymphoblastic leukemia (ALL) who are at high risk for central nervous system (CNS) relapse...
  11. pmc Lack of specificity of plasma concentrations of inhibin B and follicle-stimulating hormone for identification of azoospermic survivors of childhood cancer: a report from the St Jude lifetime cohort study
    Daniel M Green
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    J Clin Oncol 31:1324-8. 2013
    ..Although both the levels of follicle-stimulating hormone (FSH) and inhibin B are correlated with sperm concentration, their ability to predict azoospermia in survivors of childhood cancer remains uncertain...
  12. pmc Prospective medical assessment of adults surviving childhood cancer: study design, cohort characteristics, and feasibility of the St. Jude Lifetime Cohort study
    Melissa M Hudson
    Department of Oncology, Division of Cancer Survivorship, St Jude Children s Research Hospital and the University of Tennessee College of Medicine, Memphis, Tennessee, USA
    Pediatr Blood Cancer 56:825-36. 2011
    ..Jude Children's Research Hospital (SJCRH) is establishing a lifetime cohort of survivors...
  13. doi request reprint Comparison of gallium and PET scans at diagnosis and follow-up of pediatric patients with Hodgkin lymphoma
    Melissa Hines-Thomas
    University of Tennessee School of Medicine, Memphis, Tennessee, USA
    Pediatr Blood Cancer 51:198-203. 2008
    ..Positron emission tomography (PET) and gallium scans facilitate diagnosis and staging, evaluation of response to therapy, and monitoring for relapse in Hodgkin lymphoma (HL), but have not been compared in pediatric HL...
  14. pmc Utility of bone marrow biopsy at diagnosis in pediatric Hodgkin's lymphoma
    Melissa R Hines-Thomas
    Department of Oncology, St Jude Children s Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105 3678, USA
    Haematologica 95:1691-6. 2010
    ..We reviewed the cases of pediatric Hodgkin's lymphoma in our institution to determine the impact of bone marrow involvement on treatment, relapse, and survival...
  15. ncbi request reprint Itraconazole-enhanced chemotherapy toxicity in a patient with Hodgkin lymphoma
    Hamid Bashir
    Department of Internal Medicine, University of Tennessee Health Science Center, Memphis, 38105, USA
    J Pediatr Hematol Oncol 28:33-5. 2006
    ..Appropriate care should be exercised when combining cancer chemotherapy with cytochrome P450 and P-glycoprotein inhibitors, such as itraconazole...
  16. ncbi request reprint Pericardial involvement at diagnosis in pediatric Hodgkin lymphoma patients
    Hamid Bashir
    Departments of Internal Medicine and Pediatrics, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    Pediatr Blood Cancer 49:666-71. 2007
    ..Because most cases are clinically silent, the incidence, clinical course, and outcome of pericardial involvement in Hodgkin lymphoma are unknown...
  17. pmc Incidence and correlates of radiation pneumonitis in pediatric patients with partial lung irradiation
    Chiaho Hua
    Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, TN 38105 3678, USA
    Int J Radiat Oncol Biol Phys 78:143-9. 2010
    ..To provide a radiation pneumonitis risk estimate and investigate the correlation of clinical and dosimetric factors in pediatric patients receiving chest irradiation...
  18. ncbi request reprint Childhood cancer epidemiology in low-income countries
    Scott C Howard
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Cancer 112:461-72. 2008
    ..POND4kids.org), which allows collection, analysis, and sharing of data...
  19. ncbi request reprint Natural history of thyroid nodules in survivors of pediatric Hodgkin lymphoma
    Monika L Metzger
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee
    Pediatr Blood Cancer 46:314-9. 2006
    ..Ultrasonography provides an inexpensive and non-invasive method of thyroid screening, but the clinical significance of thyroid nodules detected by ultrasound screening is uncertain...
  20. pmc Screening adult survivors of childhood cancer for cardiomyopathy: comparison of echocardiography and cardiac magnetic resonance imaging
    Gregory T Armstrong
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, 262 Danny Thomas Place, Mailstop 735, Memphis, TN 38105, USA
    J Clin Oncol 30:2876-84. 2012
    ....
  21. ncbi request reprint Topotecan is active against Wilms' tumor: results of a multi-institutional phase II study
    Monika L Metzger
    St Jude Children s Research Hospital, Memphis, TN, USA
    J Clin Oncol 25:3130-6. 2007
    ..A phase II study was conducted to evaluate the activity and safety of topotecan in pediatric patients with recurrent Wilms' tumor...
  22. pmc Pediatric Hodgkin lymphoma survivors at negligible risk for significant bone mineral density deficits
    Sue C Kaste
    Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Pediatr Blood Cancer 52:516-21. 2009
    ..We hypothesized that pediatric Hodgkin lymphoma (HL) survivors would have bone mineral density (BMD) deficits compared to their peers because of osteotoxic chemotherapy during the time of greatest BMD accretion...
  23. ncbi request reprint Implementation of a data management program in a pediatric cancer unit in a low income country
    Lisa Ayoub
    International Outreach Program, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Pediatr Blood Cancer 49:23-7. 2007
    ....
  24. pmc Spinal epidural lipomatosis in children with hematologic malignancies
    Rachel C Brennan
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Ann Hematol 90:1067-74. 2011
    ..Investigation for SEL in leukemia or lymphoma patients with difficult lumbar punctures is warranted. Placement of an Ommaya reservoir may facilitate safe CNS-directed therapy in severely affected patients...
  25. pmc Management of occlusion and thrombosis associated with long-term indwelling central venous catheters
    Jacquelyn L Baskin
    Department of Oncology and International Outreach Program, St Jude Children s Research Hospital, Memphis, TN 3105 2794, USA
    Lancet 374:159-69. 2009
    ..Prevention of catheter-related thromboses includes proper positioning of the CVC and prevention of infections; anticoagulation prophylaxis is not currently recommended...
  26. doi request reprint Methotrexate-induced neurotoxicity and leukoencephalopathy in childhood acute lymphoblastic leukemia
    Deepa Bhojwani
    All authors St Jude Children s Research Hospital and Deepa Bhojwani, Jun J Yang, Hiroto Inaba, Jeffrey E Rubnitz, Monika L Metzger, Scott C Howard, Raul C Ribeiro, Sima Jeha, John T Sandlund, and Ching Hon Pui, University of Tennessee Health Sciences Center, College of Medicine, Memphis, TN
    J Clin Oncol 32:949-59. 2014
    ....
  27. ncbi request reprint Severe cardiopulmonary complications consistent with systemic inflammatory response syndrome caused by leukemia cell lysis in childhood acute myelomonocytic or monocytic leukemia
    Nobuko Hijiya
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Pediatr Blood Cancer 44:63-9. 2005
    ..Life-threatening pulmonary complications that coincide with cell lysis during early chemotherapy and that mimic systemic inflammatory response syndrome (SIRS) have been reported in patients with acute myeloid leukemia (AML)...
  28. ncbi request reprint Pediatric cancers in the new millennium: dramatic progress, new challenges
    Lisa M McGregor
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    Oncology (Williston Park) 21:809-20; discussion 820, 823-4. 2007
    ..Here we review the progress made in pediatric oncology over the past 3 decades and consider the new challenges that face us today...
  29. pmc Sperm cryopreservation practices among adolescent cancer patients at risk for infertility
    James L Klosky
    Department of Behavioral Medicine, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Pediatr Hematol Oncol 26:252-60. 2009
    ..These results suggest that sperm banking is underutilized among adolescent males newly diagnosed with cancer, and that strategies to increase the engagement in this fertility preservation method are needed...
  30. doi request reprint Histiocyte-rich xanthomatous pseudotumor mimicking relapse on positron emission tomography imaging in an adolescent with primary mediastinal diffuse large B-cell lymphoma
    Mario Otto
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN, USA
    J Pediatr Hematol Oncol 34:232-5. 2012
    ..This case is an important reminder of the limitations of positron emission tomography/computed tomography imaging in patients with lymphoma and stresses the importance of histologic confirmation of suspected treatment failure or relapse...
  31. ncbi request reprint Current therapy for Wilms' tumor
    Monika L Metzger
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    Oncologist 10:815-26. 2005
    ..At the same time, current clinical trials seek to augment therapy for patients with high-risk Wilms' tumor, including those with bilateral, anaplastic, and recurrent favorable histology tumors...
  32. ncbi request reprint Comparison of treatment outcomes of childhood Hodgkin lymphoma in two US centers and a center in Recife, Brazil
    Saunders C Hsu
    Department of Pediatrics, Division of Pediatric Hematology Oncology, Doernbecher Children s Hospital, Oregon Health and Science University, Portland, Oregon, USA
    Pediatr Blood Cancer 49:139-44. 2007
    ..Pediatric Hodgkin lymphoma (HL) has a cure rate of more than 80% in high-income countries (HIC). However, more than 80% of the world's children live in low-income countries (LIC), where the cure rate is often much lower...