Research Topics
| M Beth McCarvilleSummaryAffiliation: St. Jude Children's Research Hospital Country: USA Publications
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Detail Information
Publications
Diagnosis and staging of hepatoblastoma: imaging aspectsM Beth McCarville
Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
Pediatr Blood Cancer 59:793-9. 2012..The potential roles of new imaging techniques are presented, and differences between staging systems are addressed...
Contrast-enhanced sonography of malignant pediatric abdominal and pelvic solid tumors: preliminary safety and feasibility dataM Beth McCarville
Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, TN 38105, USA
Pediatr Radiol 42:824-33. 2012..Little information exists regarding pediatric contrast-enhanced US...- Imaging neuroblastoma: what the radiologist needs to knowM B McCarville
Department of Radiological Sciences, St Jude Children s Research Hospital, 332 Danny Thomas Place, Memphis, TN 38105, USA
Cancer Imaging 11:S44-7. 2011..With the application of the INRGSS the radiologist's role in staging children with neuroblastoma is increased. This review provides an overview of the INRGSS and the IDRFs... - Effects of chronic transfusions on abdominal sonographic abnormalities in children with sickle cell anemiaMary Beth McCarville
Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, TN 38105, USA
J Pediatr 160:281-285.e1. 2012..To assess the effects of chronic erythrocyte transfusions on prevalence of sonographic incidence of organ damage in children with sickle cell anemia (SCA)... - Comparison of whole liver and small region-of-interest measurements of MRI liver R2* in children with iron overloadM Beth McCarville
Department of Radiological Sciences, St Jude Children s Research Hospital, 262 Danny Thomas Place, Mail Stop 210, Memphis, TN 38105, USA
Pediatr Radiol 40:1360-7. 2010..A systematic investigation of the influence of the region-of-interest size and placement has not been conducted... - Clinical and CT features of benign pneumatosis intestinalis in pediatric hematopoietic stem cell transplant and oncology patientsM Beth McCarville
Department of Radiological Sciences, St Jude Children s Research Hospital, 332 North Lauderdale Street, Memphis, TN 38105, USA
Pediatr Radiol 38:1074-83. 2008..Pneumatosis intestinalis in children is associated with a wide variety of underlying conditions and often has a benign course. The CT features of this condition have not been systematically investigated... 
The cause and clinical significance of central tumor photopenia on thallium scintigraphy of pediatric osteosarcoma of the extremityM Beth McCarville
Department of Radiological Sciences, Division of Diagnostic Imaging, St Jude Children s Research Hospital, 332 N Lauderdale St, Memphis, TN 38105 2974, USA
AJR Am J Roentgenol 188:572-8. 2007....- Angiogenesis inhibitors in a murine neuroblastoma model: quantitative assessment of intratumoral blood flow with contrast-enhanced gray-scale USM Beth McCarville
Department of Radiological Sciences, St Jude Children s Research Hospital, 332 N Lauderdale St, Memphis, TN 38105 2794, USA
Radiology 240:73-81. 2006..To quantify intratumoral ultrasonographic (US) contrast agent flow at gray-scale imaging as a measure of functional tumor vascularity in an orthotopic murine neuroblastoma model treated with angiogenesis inhibitors... - Comparison of duplex and nonduplex transcranial Doppler ultrasonographyM Beth McCarville
Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, TN 38105, USA
Ultrasound Q 24:167-71. 2008..The purpose of this review is to compare and contrast the clinically relevant differences between these 2 types of equipment... - Hepatic veno-occlusive disease in children undergoing bone-marrow transplantation: usefulness of sonographic findingsM B McCarville
Department of Diagnostic Imaging, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
Pediatr Radiol 31:102-5. 2001..Reports of the usefulness of ultrasonography in the diagnosis of hepatic veno-occlusive disease (HVOD) have presented conflicting results... - The child with bone pain: malignancies and mimickersM Beth McCarville
Department of Radiological Sciences, Division of Diagnostic Imaging, St Jude Children s Research Hospital, 262 Danny Thomas Place, Mail Stop 210, Memphis, TN 38105, USA
Cancer Imaging 9:S115-21. 2009..Benign conditions are compared with the most common pediatric bone tumors, Ewing sarcoma and osteosarcoma, with an emphasis on clinical and imaging features that may aid in diagnosis... - MRI and biologic behavior of desmoid tumors in childrenM Beth McCarville
Division of Diagnostic Imaging, Department of Radiological Sciences, St Jude Children s Research Hospital, 332 N Lauderdale St, Memphis, TN 38105 2794, USA
AJR Am J Roentgenol 189:633-40. 2007..We also aimed to determine how imaging features change during adjuvant treatment and how the imaging features relate to the histologic features... - Evaluation of a comprehensive transcranial doppler screening program for children with sickle cell anemiaM Beth McCarville
Department of Radiological Sciences, St Jude Children s Research Hospital, 332 North Lauderdale Street, Memphis, Tennessee 38105 2794, USA
Pediatr Blood Cancer 50:818-21. 2008..In 2003, we instituted a comprehensive TCD screening program designed to screen all at-risk children treated at our sickle cell center... - PET-CT imaging in pediatric oncologyM Beth McCarville
Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, TN 38105, USA
Cancer Imaging 9:35-43. 2009..In this article, the technical considerations in performing pediatric PET-CT, pitfalls in the diagnostic use of PET-CT in children, and current and emerging applications of PET-CT in pediatric oncology are reviewed... - PET-CT of the normal spinal cord in childrenM Beth McCarville
Department of Radiological Sciences, St Jude Children s Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA
Acad Radiol 16:881-5. 2009..The aim of this study was to assess the correlation between age and spinal cord metabolic activity in children using positron emission tomography-computed tomography... - New frontiers in pediatric oncologic imagingM Beth McCarville
St Jude Children s Research Hospital, Memphis, TN 38105, USA
Cancer Imaging 8:87-92. 2008..The potential value, relative advantages, and limitations of these new methods in monitoring anticancer therapy in children are discussed... - Evaluation of typhlitis in children: CT versus USM Beth McCarville
Department of Radiological Sciences, Division of Diagnostic Imaging, St. Jude Children's Research Hospital, 332 N. Lauderdale St, Memphis, TN 38105-2794, USA
Pediatr Radiol 36:890-1. 2006 - The role of positron emission tomography in pediatric musculoskeletal oncologyBeth McCarville
Department of Radiological Sciences, Division of Diagnostic Imaging, St. Jude Children's Research Hospital, Mail Stop 210, 332 North Lauderdale Street, Memphis, TN 38105-2794, USA
Skeletal Radiol 35:553-4. 2006 - Distinguishing benign from malignant pulmonary nodules with helical chest CT in children with malignant solid tumorsM Beth McCarville
Department of Radiological Sciences, St Jude Children s Research Hospital, 332 N Lauderdale St, Memphis, TN 38105 2794, USA
Radiology 239:514-20. 2006..To retrospectively assess whether computed tomographic (CT) findings can indicate the benign or malignant nature of pulmonary nodules in pediatric patients with malignant solid primary tumors... - Sonographic appearance of appendicitis in a neutropenic pediatric patient after inversion appendectomyM B McCarville
Department of Diagnostic Imaging, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
Pediatr Radiol 31:578-80. 2001..Our case illustrates the importance of a complete surgical history for the interpretation of abnormal sonographic findings of the cecum... - Comparison of transcranial Doppler sonography with and without imaging in the evaluation of children with sickle cell anemiaM Beth McCarville
Department of Radiological Sciences, Division of Diagnostic Imaging, St Jude Children s Research Hospital, 332 N Lauderdale St, Memphis, TN 38015 2794, USA
AJR Am J Roentgenol 183:1117-22. 2004..However, velocities measured using the more widely available duplex transcranial Doppler imaging equipment may not be comparable. We sought to determine the magnitude and significance of the potential differences... - Secondary ovarian neoplasms in children: imaging features with histopathologic correlationM B McCarville
Department of Diagnostic Imaging, St Jude Children s Research Hospital, 332 North Lauderdale, Memphis, TN 38105 2794, USA
Pediatr Radiol 31:358-64. 2001..Although the pathologic features and imaging appearance of childhood primary ovarian neoplasms have been well described, little information is available about the malignancies that may secondarily involve the ovary... - Significance of appendiceal thickening in association with typhlitis in pediatric oncology patientsM Beth McCarville
Department of Radiological Sciences, St Jude Children s Research Hospital, 332 North Lauderdale Street, Memphis, TN 38105 2794, USA
Pediatr Radiol 34:245-9. 2004..The management of pediatric oncology patients with imaging evidence of appendiceal thickening is complex because they are generally poor surgical candidates and often have confounding clinical findings... - Abdominal ultrasound with scintigraphic and clinical correlates in infants with sickle cell anemia: baseline data from the BABY HUG trialM Beth McCarville
Department of Radiological Sciences, St Jude Children s Research Hospital, 262 Danny Thomas Pl, Mail Stop 210, Memphis, TN 38105, USA
AJR Am J Roentgenol 196:1399-404. 2011.... - Contrast-enhanced sonography in pediatricsM Beth McCarville
Department of Radiological Sciences MS 210, St Jude Children s Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA
Pediatr Radiol 41:S238-42. 2011..In this review I will discuss several proven and potential pediatric applications of contrast-enhanced sonography... - Avoiding misdiagnosing neuroblastoma as Wilms tumorPaxton V Dickson
Department of Surgery, St Jude Children s Research Hospital, Memphis, TN 38105, USA
J Pediatr Surg 43:1159-63. 2008..We reviewed our 20-year experience (1987-2006) treating patients with NBL, focusing on those with an initial diagnosis of WT, to determine presenting features that would have suggested the correct preoperative diagnosis... - Should contralateral exploratory thoracotomy be advocated for children with osteosarcoma and early unilateral pulmonary metastases?Gideon Karplus
Department of Surgery, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
J Pediatr Surg 44:665-71. 2009..The standard approach to treating unilateral metastases is ipsilateral thoracotomy with complete resection of the metastases whenever possible. We analyzed whether contralateral exploratory thoracotomy is beneficial in these patients... - A single-arm pilot phase II study of gefitinib and irinotecan in children with newly diagnosed high-risk neuroblastomaWayne L Furman
Department of Oncology, St Jude Children s Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA
Invest New Drugs 30:1660-70. 2012..This Phase II pilot study estimated the rate of response to two courses of intravenous irinotecan plus oral gefitinib in children with untreated high-risk neuroblastoma... - R2* magnetic resonance imaging of the liver in patients with iron overloadJane S Hankins
Departments of Hematology, St Jude Children s Research Hospital, Memphis, TN 38105 3678, USA
Blood 113:4853-5. 2009..98; all P < .001). This high correlation confirms prior reports, calibrates R2*-MRI measurements, and suggests its clinical utility for predicting HIC using R2*-MRI. This study was registered at www.clinicaltrials.gov as #NCT00675038... - Bevacizumab-induced transient remodeling of the vasculature in neuroblastoma xenografts results in improved delivery and efficacy of systemically administered chemotherapyPaxton V Dickson
Department of Surgery, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
Clin Cancer Res 13:3942-50. 2007..We sought to examine temporal changes in tumor vascular function in response to the anti-VEGF antibody, bevacizumab... - Imaging pediatric abdominal tumorsSue C Kaste
Department of Radiological Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee 38105-2794, USA
Semin Roentgenol 43:50-9. 2008 - Typhlitis in childhood cancerM Beth McCarville
Division of Diagnostic Imaging, Department of Radiological Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA. jude.org
Cancer 104:380-7. 2005..The classic triad of abdominal pain, fever, and neutropenia may be absent. The severity of typhlitis was related to the duration of neutropenia and the presence of fever or abdominal tenderness... - Patterns of liver iron accumulation in patients with sickle cell disease and thalassemia with iron overloadJane S Hankins
Department of Hematology, St Jude Children s Research Hospital, Memphis, TN 38105 3678, USA
Eur J Haematol 85:51-7. 2010..Pathophysiological and genetic differences affecting iron deposition and accumulation in SCD and TM warrants further investigation... - Continuous delivery of IFN-beta promotes sustained maturation of intratumoral vasculaturePaxton V Dickson
Department of Surgery, St Jude Children s Research Hospital, 332 North Lauderdale, Memphis, TN 38105, USA
Mol Cancer Res 5:531-42. 2007..These results have significant implications for the planning of combination anticancer therapy... - PET/CT characterization of fibroosseous defects in children: 18F-FDG uptake can mimic metastatic diseaseGeoffrey S Goodin
Division of Diagnostic Imaging, Department of Radiological Sciences, MS 210, St. Jude Children's Research Hospital, 332 N Lauderdale St, Memphis, TN 38105-2794, USA
AJR Am J Roentgenol 187:1124-8. 2006..Benign fibroosseous lesions may be metabolically active and thus mimic metastatic osseous disease in children with underlying malignancies. Correlative CT or other anatomic imaging can confirm the benign nature of these lesions... - Topotecan and vincristine combination is effective against advanced bilateral intraocular retinoblastoma and has manageable toxicityIbrahim Qaddoumi
Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
Cancer 118:5663-70. 2012..New, effective chemotherapeutic agents are needed for intraocular retinoblastoma... - Dose escalation of intravenous irinotecan using oral cefpodoxime: a phase I study in pediatric patients with refractory solid tumorsLisa M McGregor
Department of Oncology, St Jude Children s Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA
Pediatr Blood Cancer 58:372-9. 2012..Administration of an oral cephalosporin allowed advancement of the dosage of oral irinotecan. This study investigates whether administration of an oral cephalosporin increases the maximum tolerated dose (MTD) of intravenous irinotecan... - Phase I and clinical pharmacology study of bevacizumab, sorafenib, and low-dose cyclophosphamide in children and young adults with refractory/recurrent solid tumorsFariba Navid
Departments of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
Clin Cancer Res 19:236-46. 2013.... - Tyrosine kinase inhibitor enhances the bioavailability of oral irinotecan in pediatric patients with refractory solid tumorsWayne L Furman
Department of Oncology, St Jude Children s Research Hospital, 262 Danny Thomas Pl, Memphis, TN 38105 3678, USA
J Clin Oncol 27:4599-604. 2009..To assess the effect of gefitinib on the pharmacokinetics of IV irinotecan and on the bioavailability of a single oral dose of irinotecan... - Outcome after local recurrence of osteosarcoma: the St. Jude Children's Research Hospital experience (1970-2000)Carlos Rodriguez-Galindo
Department of Hematology Oncology, St Jude Children s Research Hospital, and Department of Pediatrics, University of Tennessee, Memphis, USA
Cancer 100:1928-35. 2004..Despite improvements in therapy for osteosarcoma, approximately 4-10% of patients experience a local recurrence and have a poor prognosis... - Natural history of thyroid nodules in survivors of pediatric Hodgkin lymphomaMonika L Metzger
Department of Hematology-Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee
Pediatr Blood Cancer 46:314-9. 2006..Only patients with a palpable mass or clinical symptoms need more extensive evaluation, including Doppler-flow ultrasonography and fine-needle aspiration... - Metastatic osteosarcomaNajat C Daw
Department of Hematology Oncology, St Jude Children s Research Hospital, University of Tennessee Health Science Center, Memphis, Tennessee 38105 2794, USA
Cancer 106:403-12. 2006..The initial study (OS-86) used ifosfamide, cisplatin, doxorubicin, and high-dose methotrexate, and the subsequent study (OS-91) used the same agents at similar doses, but carboplatin was substituted for cisplatin... - The natural history of conditional transcranial Doppler flow velocities in children with sickle cell anaemiaJane S Hankins
Department of Hematology, Comprehensive Sickle Cell Center, St Jude Children s Research Hospital, Memphis, TN 38105, USA
Br J Haematol 142:94-9. 2008..Our data document a high conversion rate to abnormal velocities among untreated children with SCA. Therapy should be considered for the prevention of conversion to abnormal TCD velocities... - Pulmonary nodules discovered during the initial evaluation of pediatric patients with bone and soft-tissue sarcomaMichael J Absalon
Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
Pediatr Blood Cancer 50:1147-53. 2008..Recent technical advances in CT imaging and data processing have improved the ability to detect small pulmonary nodules in children with bone and soft-tissue sarcoma undergoing radiologic imaging of the chest... - Preservation of spleen and brain function in children with sickle cell anemia treated with hydroxyureaJane S Hankins
Department of Hematology, Comprehensive Sickle Cell Center, St Jude Children s Research Hospital, Memphis, Tennessee, USA
Pediatr Blood Cancer 50:293-7. 2008..Chronic organ damage is an insidious process in patients with sickle cell anemia (SCA). Although hydroxyurea prevents acute vaso-occlusive events, its effects on the preservation of organ function remain undefined... - Case reports: polymethylmethacrylate lung embolus after limb-salvage surgery of the distal femurNajat C Daw
Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
Clin Orthop Relat Res 448:252-6. 2006..Awareness of this potential complication should prompt investigation of possible pulmonary embolism and may prevent unnecessary thoracotomy... - Estimation of potential excess cancer incidence in pediatric 201Tl imagingSue C Kaste
Department of Radiological Sciences, St Jude Children s Research Hospital, and Department of Radiology, College of Medicine, University of Tennessee School of Health Science Center, 262 Danny Thomas Place, Mailstop 220, Memphis, TN 38105, USA
AJR Am J Roentgenol 194:245-9. 2010..The purpose of our study was to estimate the potential excess lifetime cancer incidence and mortality associated with thallium bone imaging in pediatric patients... - Pulmonary alveolar proteinosis in pediatric leukemiaHiroto Inaba
Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
Pediatr Blood Cancer 51:66-70. 2008..Only isolated cases of PAP have been reported, and pediatric experience is limited... - Simultaneous field and R2 mapping to quantify liver iron content using autoregressive moving average modelingBrian A Taylor
Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, Tennessee, USA
J Magn Reson Imaging 35:1125-32. 2012.... - Efficacy of zoledronate against neuroblastomaPaxton V Dickson
Department of Surgery, St. Jude Children's Research Hospital, Memphis, TN 38105, USA
Surgery 140:227-35. 2006..These results suggest that clinical investigation of zoledronate or similar bisphosphonates as adjuvant therapy in neuroblastoma patients is warranted... - In vivo bioluminescence imaging for early detection and monitoring of disease progression in a murine model of neuroblastomaPaxton V Dickson
Department of Surgery, St Jude Children s Research Hospital, Memphis, TN 38105, USA
J Pediatr Surg 42:1172-9. 2007..We evaluated the potential of bioluminescence imaging (BLI) for early tumor detection, demonstrating occult sites of disseminated disease and assessing disease progression in a murine model of neuroblastoma... - Clinical utility of computed tomography screening of chest, abdomen, and sinuses before hematopoietic stem cell transplantation: the St. Jude experienceKimberly A Kasow
Division of Bone Marrow Transplantation and Cellular Therapy, Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
Biol Blood Marrow Transplant 15:490-5. 2009..The decision to perform chest CT should be made judiciously based on a careful history and physical examination. Sinus imaging, which was frequently abnormal, may be justified in all patients to plan post-HSCT care... - Combination of gemcitabine and docetaxel in the treatment of children and young adults with refractory bone sarcomaFariba Navid
Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
Cancer 113:419-25. 2008..The combination of gemcitabine and docetaxel has demonstrated promise in sarcomas diagnosed in adults. In the current study, the toxicity and efficacy of this combination were evaluated in pediatric sarcomas... - PET/CT in the evaluation of childhood sarcomasM Beth McCarville
Department of Radiological Sciences, St. Jude Children's Research Hospital, 332 N Lauderdale St, Memphis, TN 38105, USA
AJR Am J Roentgenol 184:1293-304. 2005..It was useful in monitoring response to chemotherapy, radiation therapy, and radiofrequency ablation and aided the postoperative evaluation of tumor resection sites... - Prolactinoma as the first manifestation of Gardner's syndromeGeoffrey S Goodin
Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, Tennessee, USA
Pediatr Blood Cancer 50:409-12. 2008..A germline mutation of the APC (adenomatous polyposis coli) gene was identified. Our case illustrates the association between prolactinoma and FAP, which may represent a rare subtype of Gardner's and BTP syndromes... - Thyroid carcinoma presenting in childhood or after treatment of childhood malignancies: An institutional experience and review of the literatureKenneth W Gow
Department of Surgery, St Jude Children's Research Hospital, Memphis, TN, USA
J Pediatr Surg 38:1574-80. 2003.... - Role of lymphoscintigraphy and sentinel lymph node biopsy in the management of pediatric melanoma and sarcomaLalit Parida
Department of Surgery, St Jude Children s Research Hospital, Memphis, TN, USA
Pediatr Surg Int 28:571-8. 2012..We report the experience of two children's hospitals that utilize this technique to identify sentinel lymph nodes for lymph-node biopsy and dissection... - Clofarabine in refractory Langerhans cell histiocytosisCarlos Rodriguez-Galindo
Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
Pediatr Blood Cancer 51:703-6. 2008..In this report we describe significant single agent activity of clofarabine in disseminated LCH refractory to salvage regimens, including cladribine... - A modified surgical procedure for microdialysis probe implantation in the lateral ventricle of a FVB mouseJun Shen
Department of Pharmaceutical Sciences, St Jude Children s Research Hospital, 332 North Lauderdale, Memphis, Tennessee 38105 2794, USA
J Pharm Sci 97:5013-23. 2008..Thus, we propose that this modified procedure for placement of the microdialysis probe is superior to the conventional perpendicular method previously reported... - Primary intrathoracic dermatofibrosarcoma protuberansLauren King
Departmentsof Pathology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
Am J Surg Pathol 36:1897-902. 2012..The implication of this case on expanding the clinical spectrum of DFSP will have to be elucidated in future studies by applying molecular pathologic tools in deep-seated sarcomas in the proper morphologic context... - US and MRI of pediatric ocular masses with histopathological correlationRachel C Brennan
Department of Oncology, St Jude Children s Research Hospital, MS 260, 262 Danny Thomas Place, Memphis, TN 38105, USA
Pediatr Radiol 42:738-49. 2012..Features useful in discriminating among these entities are emphasized... - Imaging recommendations for malignant liver neoplasms in childrenM Beth McCarville
Department of Radiological Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA
Pediatr Blood Cancer 46:2-7. 2006 - Synovial sarcoma in pediatric patientsM Beth McCarville
Department of Diagnostic Imaging, Mail Stop 210, St. Jude Children's Research Hospital, 332 N. Lauderdale St, Memphis, TN 38105-2794, USA
AJR Am J Roentgenol 179:797-801. 2002 - Phase I trial of temozolomide and protracted irinotecan in pediatric patients with refractory solid tumorsLars M Wagner
Division of Pediatric Hematology Oncology, University of Utah Primary Children s Medical Center, Salt Lake City, Utah, USA
Clin Cancer Res 10:840-8. 2004..The purpose is to estimate the maximum-tolerated dose (MTD) of temozolomide and irinotecan given on a protracted schedule in 28-day courses to pediatric patients with refractory solid tumors... - Giant cell tumor of bone with pulmonary metastasesYasuhiro Okamoto
Med Pediatr Oncol 41:454-9. 2003 - Temozolomide and intravenous irinotecan for treatment of advanced Ewing sarcomaLars M Wagner
Division of Hematology Oncology, Primary Children s Medical Center, Salt Lake City, Utah, USA
Pediatr Blood Cancer 48:132-9. 2007..Because responses were seen in patients with Ewing sarcoma (ES) on that trial, additional patients were treated with this combination following study completion...