Kevin R Krull

Summary

Affiliation: St. Jude Children's Research Hospital
Country: USA

Publications

  1. doi request reprint Screening for neurocognitive impairment in pediatric cancer long-term survivors
    Kevin R Krull
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, 332 N Lauderdale St, MS 735, Memphis, TN 38105 2794, USA
    J Clin Oncol 26:4138-43. 2008
  2. doi request reprint Sex-specific attention problems in long-term survivors of pediatric acute lymphoblastic leukemia
    Neelam Jain
    Department of Psychology, University of Houston, and Child Psychology, Texas Children s Hospital, Houston, Texas, USA
    Cancer 115:4238-45. 2009
  3. pmc Long-term decline in intelligence among adult survivors of childhood acute lymphoblastic leukemia treated with cranial radiation
    Kevin R Krull
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN 38105 3678, USA
    Blood 122:550-3. 2013
  4. pmc Genetic mediators of neurocognitive outcomes in survivors of childhood acute lymphoblastic leukemia
    Kevin R Krull
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, 262 Danny Thomas Place, MS 735, Memphis, TN 38105 3678, USA
    J Clin Oncol 31:2182-8. 2013
  5. pmc Cerebral white matter integrity and executive function in adult survivors of childhood medulloblastoma
    Tara M Brinkman
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, Tennessee 38105 3678, USA
    Neuro Oncol 14:iv25-36. 2012
  6. pmc Neurocognitive function and CNS integrity in adult survivors of childhood hodgkin lymphoma
    Kevin R Krull
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, 262 Danny Thomas Place, MS 735, Memphis, TN 38105 3678, USA
    J Clin Oncol 30:3618-24. 2012
  7. pmc Adolescent behavior and adult health status in childhood cancer survivors
    Kevin R Krull
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN 38105 3678, USA
    J Cancer Surviv 4:210-7. 2010
  8. pmc Reliability and validity of the Childhood Cancer Survivor Study Neurocognitive Questionnaire
    Kevin R Krull
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Cancer 113:2188-97. 2008
  9. pmc Symptoms of attention-deficit/hyperactivity disorder in long-term survivors of childhood leukemia
    Kevin R Krull
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Pediatr Blood Cancer 57:1191-6. 2011
  10. ncbi request reprint Folate pathway genetic polymorphisms are related to attention disorders in childhood leukemia survivors
    Kevin R Krull
    Learning Support Center for Child Psychology, Texas Children s Hospital, Houston, TX, USA
    J Pediatr 152:101-5. 2008

Detail Information

Publications36

  1. doi request reprint Screening for neurocognitive impairment in pediatric cancer long-term survivors
    Kevin R Krull
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, 332 N Lauderdale St, MS 735, Memphis, TN 38105 2794, USA
    J Clin Oncol 26:4138-43. 2008
    ..We report reliability and validity data on a brief neurocognitive screening method that could be used to routinely screen patients in need of comprehensive follow-up...
  2. doi request reprint Sex-specific attention problems in long-term survivors of pediatric acute lymphoblastic leukemia
    Neelam Jain
    Department of Psychology, University of Houston, and Child Psychology, Texas Children s Hospital, Houston, Texas, USA
    Cancer 115:4238-45. 2009
    ..The purpose of this study was to evaluate the pattern of attention problems in male and female long-term survivors of pediatric acute lymphoblastic leukemia (ALL)...
  3. pmc Long-term decline in intelligence among adult survivors of childhood acute lymphoblastic leukemia treated with cranial radiation
    Kevin R Krull
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN 38105 3678, USA
    Blood 122:550-3. 2013
    ..This trial was registered at clinicaltrials.gov as no. NCT00760656. ..
  4. pmc Genetic mediators of neurocognitive outcomes in survivors of childhood acute lymphoblastic leukemia
    Kevin R Krull
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, 262 Danny Thomas Place, MS 735, Memphis, TN 38105 3678, USA
    J Clin Oncol 31:2182-8. 2013
    ..This study examined genetic polymorphisms associated with variability in neurocognitive outcome...
  5. pmc Cerebral white matter integrity and executive function in adult survivors of childhood medulloblastoma
    Tara M Brinkman
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, Tennessee 38105 3678, USA
    Neuro Oncol 14:iv25-36. 2012
    ..Future research integrating diffusion tensor imaging should be a priority to more rigorously evaluate long-term consequences of cancer treatment and to inform cognitive intervention trials in this high-risk population...
  6. pmc Neurocognitive function and CNS integrity in adult survivors of childhood hodgkin lymphoma
    Kevin R Krull
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, 262 Danny Thomas Place, MS 735, Memphis, TN 38105 3678, USA
    J Clin Oncol 30:3618-24. 2012
    ..The aim of this study was to examine neurocognitive and brain imaging outcomes in adult survivors of childhood HL...
  7. pmc Adolescent behavior and adult health status in childhood cancer survivors
    Kevin R Krull
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN 38105 3678, USA
    J Cancer Surviv 4:210-7. 2010
    ....
  8. pmc Reliability and validity of the Childhood Cancer Survivor Study Neurocognitive Questionnaire
    Kevin R Krull
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Cancer 113:2188-97. 2008
    ..This study reports the results of a questionnaire developed to identify those survivors who may be experiencing neurocognitive problems...
  9. pmc Symptoms of attention-deficit/hyperactivity disorder in long-term survivors of childhood leukemia
    Kevin R Krull
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Pediatr Blood Cancer 57:1191-6. 2011
    ..Survivors of childhood acute lymphoblastic leukemia (ALL) sometimes have clinical features that suggest attention-deficit/hyperactivity disorder (ADHD), though few studies have examined specific symptoms in survivors...
  10. ncbi request reprint Folate pathway genetic polymorphisms are related to attention disorders in childhood leukemia survivors
    Kevin R Krull
    Learning Support Center for Child Psychology, Texas Children s Hospital, Houston, TX, USA
    J Pediatr 152:101-5. 2008
    ....
  11. pmc Neurocognitive functioning and health-related behaviours in adult survivors of childhood cancer: a report from the Childhood Cancer Survivor Study
    Kevin R Krull
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN 38105 3678, United States
    Eur J Cancer 47:1380-8. 2011
    ..Positive health-related behaviours are essential for the future wellbeing of childhood cancer survivors, though relatively few maintain healthy behaviours into adulthood...
  12. pmc Antioxidant enzyme polymorphisms and neuropsychological outcomes in medulloblastoma survivors: a report from the Childhood Cancer Survivor Study
    Julienne Brackett
    Department of Pediatrics, Texas Children s Cancer Center, Baylor College of Medicine, Houston, TX, USA
    Neuro Oncol 14:1018-25. 2012
    ....
  13. pmc Physiologic frailty as a sign of accelerated aging among adult survivors of childhood cancer: a report from the St Jude Lifetime cohort study
    Kirsten K Ness
    Kirsten K Ness, Kevin R Krull, Kendra E Jones, Daniel A Mulrooney, Gregory T Armstrong, Daniel M Green, Wassim Chemaitilly, Webb A Smith, Carmen L Wilson, Kyla Shelton, Deo Kumar Srivastava, Sabeen Ali, Leslie L Robison, Melissa M Hudson, St Jude Children s Research Hospital, Memphis, TN Charles A Sklar, Memorial Sloan Kettering Cancer Center, New York, NY
    J Clin Oncol 31:4496-503. 2013
    ..9% of individuals 65 years old and older (9.6% of women; 5.2% of men), has not been assessed among adult childhood cancer survivors (CCS). We estimated the prevalence of frailty and examined associations with morbidity and mortality...
  14. ncbi request reprint Dexamethasone exposure and memory function in adult survivors of childhood acute lymphoblastic leukemia: A report from the SJLIFE cohort
    Michelle N Edelmann
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, Tennessee
    Pediatr Blood Cancer 60:1778-84. 2013
    ..As glucocorticoids influence hippocampal function, we investigated memory networks in survivors of childhood ALL treated with dexamethasone or prednisone...
  15. pmc Prevalence and predictors of prescription psychoactive medication use in adult survivors of childhood cancer: a report from the Childhood Cancer Survivor Study
    Tara M Brinkman
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Cancer Surviv 7:104-14. 2013
    ....
  16. pmc Region-specific radiotherapy and neuropsychological outcomes in adult survivors of childhood CNS malignancies
    Gregory T Armstrong
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, 262 Danny Thomas Place, MS 735, Memphis, TN 38105 3678, USA
    Neuro Oncol 12:1173-86. 2010
    ..Survivors with a history of radiation exposure to temporal brain regions are at increased risk for impairment in memory and social functioning...
  17. ncbi request reprint Suicide ideation and associated mortality in adult survivors of childhood cancer
    Tara M Brinkman
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, Tennessee
    Cancer 120:271-7. 2014
    ....
  18. pmc Association between the prevalence of symptoms and health-related quality of life in adult survivors of childhood cancer: a report from the St Jude Lifetime Cohort study
    I Chan Huang
    I Chan Huang, Kelly Kenzik, and Elizabeth Shenkman, University of Florida, Gainesville, FL and Tara M Brinkman, James G Gurney, Kirsten K Ness, Jennifer Lanctot, Leslie L Robison, Melissa M Hudson, and Kevin R Krull, St Jude Children s Research Hospital, Memphis, TN
    J Clin Oncol 31:4242-51. 2013
    ..We investigated the association between prevalence of symptoms and health-related quality of life (HRQOL) in adult survivors of childhood cancer enrolled in the St Jude Lifetime Cohort study...
  19. pmc Psychoactive medication use and neurocognitive function in adult survivors of childhood cancer: a report from the Childhood Cancer Survivor study
    Tara M Brinkman
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Pediatr Blood Cancer 60:486-93. 2013
    ..Psychoactive medication treatment has been associated with adverse effects on specific neurocognitive processes in non-cancer populations, yet these associations have not been examined in adult survivors of childhood cancer...
  20. pmc Clinical ascertainment of health outcomes among adults treated for childhood cancer
    Melissa M Hudson
    Division of Cancer Survivorship, Department of Oncology, St Jude Children s Research Hospital and the University of Tennessee College of Medicine, Memphis, TN 38105, USA
    JAMA 309:2371-81. 2013
    ..A large population of survivors has not been evaluated using a comprehensive systematic clinical assessment to determine the prevalence of chronic health conditions...
  21. pmc Risk factors for obesity in adult survivors of childhood cancer: a report from the Childhood Cancer Survivor Study
    Daniel M Green
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, 262 Danny Thomas Place, Mail Stop 735, Memphis, TN 38105 2794, USA
    J Clin Oncol 30:246-55. 2012
    ..Many Childhood Cancer Survivor Study (CCSS) participants are at increased risk for obesity. The etiology of their obesity is likely multifactorial but not well understood...
  22. pmc Prospective medical assessment of adults surviving childhood cancer: study design, cohort characteristics, and feasibility of the St. Jude Lifetime Cohort study
    Melissa M Hudson
    Department of Oncology, Division of Cancer Survivorship, St Jude Children s Research Hospital and the University of Tennessee College of Medicine, Memphis, Tennessee, USA
    Pediatr Blood Cancer 56:825-36. 2011
    ..Jude Children's Research Hospital (SJCRH) is establishing a lifetime cohort of survivors...
  23. pmc Evaluation of memory impairment in aging adult survivors of childhood acute lymphoblastic leukemia treated with cranial radiotherapy
    Gregory T Armstrong
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Natl Cancer Inst 105:899-907. 2013
    ..Cranial radiotherapy (CRT) is a known risk factor for neurocognitive impairment in survivors of childhood cancer and may increase risk for mild cognitive impairment and dementia in adulthood...
  24. pmc Neuromuscular impairments in adult survivors of childhood acute lymphoblastic leukemia: associations with physical performance and chemotherapy doses
    Kirsten K Ness
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, Tennessee 38138, USA
    Cancer 118:828-38. 2012
    ....
  25. pmc Fatigue, vitality, sleep, and neurocognitive functioning in adult survivors of childhood cancer: a report from the Childhood Cancer Survivor Study
    Nancy R Clanton
    Department of Psychology, St Jude Children s Research Hospital, Memphis, Tennessee
    Cancer 117:2559-68. 2011
    ..Long-term survivors of childhood cancer are at risk for fatigue, sleep problems, and neurocognitive impairment, although the association between these outcomes has not been previously examined...
  26. doi request reprint Restricted access to the environment and quality of life in adult survivors of childhood brain tumors
    Tara M Brinkman
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Neurooncol 111:195-203. 2013
    ..Restricted environmental access was associated with reduced HRQOL and diminished social functioning. Interventions directed at improving physical mobility may have significant impact on survivor quality of life...
  27. pmc Long-term outcomes among adult survivors of childhood central nervous system malignancies in the Childhood Cancer Survivor Study
    Gregory T Armstrong
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, 262 Danny Thomas Place, Mail Stop 735, Memphis, TN 38105, USA
    J Natl Cancer Inst 101:946-58. 2009
    ....
  28. pmc Pain in long-term adult survivors of childhood cancers and their siblings: a report from the Childhood Cancer Survivor Study
    Qian Lu
    Department of Psychology, University of Houston, Houston, TX 77204 5022, USA
    Pain 152:2616-24. 2011
    ..These findings contribute to the understanding of pain and associated risk factors among adult survivors of childhood cancer and suggest areas of focus for pain intervention...
  29. doi request reprint Neuropsychological outcome following intensity-modulated radiation therapy for pediatric medulloblastoma
    Neelam Jain
    Learning Support Center for Child Psychology, Texas Children s Hospital, Houston, Texas, USA
    Pediatr Blood Cancer 51:275-9. 2008
    ..This study compared the impact of the two treatments on measures of neurocognitive functioning...
  30. pmc Folate pathway polymorphisms predict deficits in attention and processing speed after childhood leukemia therapy
    Kala Y Kamdar
    Department of Pediatrics, Baylor College of Medicine, Texas Children s Cancer Center, Houston, TX, USA
    Pediatr Blood Cancer 57:454-60. 2011
    ..We evaluated the relationship between folate pathway polymorphisms and neurocognitive impairment after childhood ALL chemotherapy...
  31. pmc Cognition in children with sensorineural hearing loss: etiologic considerations
    Suzanne K Pierson
    Learning Support Center for Child Psychology, Texas Children s Hospital, and Allied Health Sciences and Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030 2399, USA
    Laryngoscope 117:1661-5. 2007
    ..The present study focused on the development of visual and fine motor skills in a sample of preschool-age children diagnosed with sensorineural hearing loss with no known neurologic conditions (n=36)...
  32. pmc Chemotherapy-related changes in central nervous system phospholipids and neurocognitive function in childhood acute lymphoblastic leukemia
    Kevin R Krull
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN, USA kevin
    Leuk Lymphoma 54:535-40. 2013
    ..Post-induction LPC was associated with verbal working memory (p = 0.007). Results indicate that early changes in phospholipids are related to neurocognitive decline and suggest a chemotherapy impact on white matter integrity...
  33. ncbi request reprint Oxidative stress and executive function in children receiving chemotherapy for acute lymphoblastic leukemia
    Joshua E Caron
    Veteran s Association Medical Center, Memphis, Tennessee, USA
    Pediatr Blood Cancer 53:551-6. 2009
    ..Biomarkers of oxidative stress (e.g., oxidated phosphatidylcholine) in cerebral spinal fluid (CSF) have been correlated with intensity of methotrexate (MTX) treatment, suggesting an association with acute central nervous system toxicity...
  34. ncbi request reprint Neuropsychological testing in the screening for cochlear implant candidacy
    Walter Kutz
    Bobby R Alford Department of Otolaryngology and Communicative Sciences, Baylor College of Medicine, Houston, TX, USA
    Laryngoscope 113:57-62. 2003
    ..To demonstrate the utility of neuropsychological assessment in the screening process for pediatric cochlear implant candidacy...
  35. ncbi request reprint Brief report: effect of intravenous methotrexate dose and infusion rate on neuropsychological function one year after diagnosis of acute lymphoblastic leukemia
    Marissa E Carey
    West Virginia University, Department of Behavioral Medicine and Psychiatry, 930 Chestnut Ridge Road, PO Box 9137, Morgantown, West Virginia 26505, USA
    J Pediatr Psychol 32:189-93. 2007
    ..To compare the effects of two intravenous (IV) methotrexate (MTX) infusion protocols on cognitive function in children newly diagnosed with acute lymphoblastic leukemia (ALL)...
  36. ncbi request reprint Neuropsychological testing in the screening for cochlear implant candidacy
    Walter Kutz
    Bobby R Alford Department of Otolarynology and Communicative Sciences, Baylor College of Medicine, Houston TX 77030, USA
    Laryngoscope 113:763-6. 2003
    ..To demonstrate the utility of neuropsychological assessment in the screening process for pediatric cochlear implant candidacy...

Research Grants1

  1. Risk for Psychopathology and Neurocognitive Impairment in Leukemia Survivors
    Kevin R Krull; Fiscal Year: 2010
    ..Accurate risk identification would permit the development of tailored behavioral treatments and/or preventative interventions designed to improve functional outcome and quality of life. ..