Research Topics
| A J KivitzSummaryAffiliation: St. John's Mercy Medical Center Country: USA Publications
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Detail Information
Publications
Efficacy and safety of rofecoxib 12.5 mg versus nabumetone 1,000 mg in patients with osteoarthritis of the knee: a randomized controlled trialAlan J Kivitz
Altoona Center for Clinical Research, Duncansville, Pennsylvania, USA
J Am Geriatr Soc 52:666-74. 2004..CONCLUSION: Rofecoxib 12.5 mg daily demonstrated better efficacy over 6 weeks of treatment and quicker onset of OA efficacy over the first 6 days than nabumetone 1,000 mg daily. Both therapies were generally well tolerated...
Clinical assessment of pain, tolerability, and preference of an autoinjection pen versus a prefilled syringe for patient self-administration of the fully human, monoclonal antibody adalimumab: the TOUCH trialAlan Kivitz
Altoona Center for Clinical Research, Duncansville, Pennsylvania 16635, USA
Clin Ther 28:1619-29. 2006....
HUMIRA pen: a novel autoinjection device for subcutaneous injection of the fully human monoclonal antibody adalimumabAlan Kivitz
Altoona Center for Clinical Research, 1125 Old Route 220 North, Duncansville, PA 16635, USA
Expert Rev Med Devices 4:109-16. 2007..The adalimumab Pen offers these benefits and recent evidence indicates that patients overwhelmingly prefer the adalimumab Pen to the prefilled syringe...
Comparative efficacy and safety of celecoxib and naproxen in the treatment of osteoarthritis of the hipA J Kivitz
Altoona Center for Clinical Research, Altoona, PA, USA
J Int Med Res 29:467-79. 2001..Both drugs were generally well tolerated. Celecoxib at a dose of 200 mg/day is as effective as a standard therapeutic dose of the conventional NSAID, naproxen, in reducing the pain associated with OA of the hip...
A comparison of the efficacy and safety of celecoxib 200 mg and celecoxib 400 mg once daily in treating the signs and symptoms of psoriatic arthritisAlan J Kivitz
Department of Rheumatology, Altoona Center for Clinical Research, Duncansville, PA, USA
Semin Arthritis Rheum 37:164-73. 2007..To evaluate the efficacy of the cyclooxygenase-2 selective inhibitor celecoxib in treating patients with psoriatic arthritis (PsA) in flare...
Comparison of the effectiveness and tolerability of lidocaine patch 5% versus celecoxib for osteoarthritis-related knee pain: post hoc analysis of a 12 week, prospective, randomized, active-controlled, open-label, parallel-group trial in adultsAlan Kivitz
Altoona Center for Clinical Research, 1125 Old Route 220 North, Duncansville, PA 16635, USA
Clin Ther 30:2366-77. 2008..Cyclooxygenase-2 (COX-2) selective inhibitors and nonselective NSAIDs are commonly used to treat osteoarthritis (OA) of the knee...
Reduced incidence of gastroduodenal ulcers associated with lumiracoxib compared with ibuprofen in patients with rheumatoid arthritisA J Kivitz
Altoona Center for Clinical Research, Duncansville, PA, USA
Aliment Pharmacol Ther 19:1189-98. 2004..5% vs. 7.9-8.8% for the other groups). CONCLUSIONS: Lumiracoxib demonstrated gastroduodenal safety superior to ibuprofen and similar to celecoxib in patients with rheumatoid arthritis...
Safety and efficacy of adalimumab in treatment of patients with psoriatic arthritis who had failed disease modifying antirheumatic drug therapyMark C Genovese
Division of Immunology and Rheumatology, Stanford University Medical Center, Palo Alto, California 94304, USA
J Rheumatol 34:1040-50. 2007..To demonstrate the safety and efficacy of adalimumab for the treatment of active psoriatic arthritis (PsA) in patients with an inadequate response to disease modifying antirheumatic drugs (DMARD)...
A randomized, double-blinded, placebo-controlled clinical trial of LY333013, a selective inhibitor of group II secretory phospholipase A2, in the treatment of rheumatoid arthritisJohn D Bradley
Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA
J Rheumatol 32:417-23. 2005..To evaluate the efficacy and safety of a selective inhibitor of secretory phospholipase (sPLA2), LY333013, in the treatment of rheumatoid arthritis (RA)...
Efficacy and safety of rilonacept (interleukin-1 Trap) in patients with cryopyrin-associated periodic syndromes: results from two sequential placebo-controlled studiesHal M Hoffman
Division of Rheumatology and Allergy Immunology, University of California at San Diego, La Jolla, CA 92093 0635, USA
Arthritis Rheum 58:2443-52. 2008....
Immune responses following administration of influenza and pneumococcal vaccines to patients with rheumatoid arthritis receiving adalimumabJeffrey L Kaine
Sarasota Arthritis Research Center, Sarasota, Florida 34239, USA
J Rheumatol 34:272-9. 2007..This study compared the immunogenicity of influenza and pneumococcal vaccines in adult patients with rheumatoid arthritis (RA) receiving adalimumab or placebo...
Etanercept treatment of psoriatic arthritis: safety, efficacy, and effect on disease progressionPhilip J Mease
Seattle Rheumatology Associates, Seattle, Washington 98104, USA
Arthritis Rheum 50:2264-72. 2004..In this study, we further evaluated the safety, efficacy, and effect on radiographic progression of etanercept in patients with PsA...
A comparison of valdecoxib and naproxen in the treatment of rheumatoid arthritis symptomsGary W Williams
Department of Medicine, Scripps Clinic, La Jolla, California 92037, USA
Clin Ther 28:204-21. 2006..The overall safety and tolerability profiles of valdecoxib and naproxen were also compared...
Pain management in osteoarthritis: a focus on onset of efficacy--a comparison of rofecoxib, celecoxib, acetaminophen, and nabumetone across four clinical trialsWendy P Battisti
Merck and Co, Inc, West Point, Pennsylvania 19486, USA
J Pain 5:511-20. 2004..Rofecoxib provides significantly faster time to onset of efficacy and better improvement on multiple measures versus the comparators...
Continued inhibition of radiographic progression in patients with psoriatic arthritis following 2 years of treatment with etanerceptPhilip J Mease
Seattle Rheumatology Associates, Seattle, Washington 98104, USA
J Rheumatol 33:712-21. 2006..Clinical and radiographic responses were evaluated in patients with psoriatic arthritis (PsA) treated for up to 2 years with etanercept...
Comparison of the COX-inhibiting nitric oxide donator AZD3582 and rofecoxib in treating the signs and symptoms of Osteoarthritis of the kneeThomas J Schnitzer
Northwestern Center for Clinical Research, Chicago, Illinois 60611, USA
Arthritis Rheum 53:827-37. 2005....
Denosumab in postmenopausal women with low bone mineral densityMichael R McClung
Providence Portland Medical Center, Portland, Oreg, USA
N Engl J Med 354:821-31. 2006..The fully human monoclonal antibody denosumab (formerly known as AMG 162) binds RANKL with high affinity and specificity and inhibits RANKL action...
