Joseph D Khoury

Summary

Affiliation: St. Jude Children's Research Hospital
Country: USA

Publications

  1. ncbi request reprint Ewing sarcoma family of tumors
    Joseph D Khoury
    Department of Pathology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Adv Anat Pathol 12:212-20. 2005
  2. ncbi request reprint Nephroblastic neoplasms
    Joseph D Khoury
    Department of Pathology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Clin Lab Med 25:341-61, vi-vii. 2005
  3. pmc Copy number gains in EGFR and copy number losses in PTEN are common events in osteosarcoma tumors
    Serena S Freeman
    Department of Pathology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Cancer 113:1453-61. 2008
  4. ncbi request reprint Telangiectatic osteosarcoma: the St. Jude Children's Research Hospital's experience
    Aaron Weiss
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Cancer 109:1627-37. 2007
  5. pmc ICAM-2 expression mediates a membrane-actin link, confers a nonmetastatic phenotype and reflects favorable tumor stage or histology in neuroblastoma
    Karina Jin Yoon
    Department of Molecular Pharmacology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    PLoS ONE 3:e3629. 2008
  6. pmc Grading of nonrhabdomyosarcoma soft tissue sarcoma in children and adolescents: a comparison of parameters used for the Fédération Nationale des Centers de Lutte Contre le Cancer and Pediatric Oncology Group Systems
    Joseph D Khoury
    Department of Pathology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Cancer 116:2266-74. 2010
  7. ncbi request reprint St. Jude Children's Research Hospital, Memphis, Tennessee: gestational choriocarcinoma
    Aaron Weiss
    Department of Hematology Oncology, St Jude Children s Research Hospital, and Department of Radiology, University of Tennessee College of Medicine, Memphis, Tennessee 38105 2794, USA
    Pediatr Blood Cancer 47:640-6. 2006
  8. ncbi request reprint Significance of pleural effusion in neuroblastoma
    Himesh Gupta
    Department of Surgery, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Pediatr Blood Cancer 49:906-8. 2007
  9. ncbi request reprint MRI and biologic behavior of desmoid tumors in children
    M Beth McCarville
    Division of Diagnostic Imaging, Department of Radiological Sciences, St Jude Children s Research Hospital, 332 N Lauderdale St, Memphis, TN 38105 2794, USA
    AJR Am J Roentgenol 189:633-40. 2007
  10. ncbi request reprint Pharmacologic inhibition of cyclin-dependent kinase 4/6 activity arrests proliferation in myoblasts and rhabdomyosarcoma-derived cells
    Raya Saab
    Department of Hematology Oncology, St Jude Children s Research Hospital, 332 North Lauderdale Street, Memphis, TN 38105, USA
    Mol Cancer Ther 5:1299-308. 2006

Collaborators

Detail Information

Publications22

  1. ncbi request reprint Ewing sarcoma family of tumors
    Joseph D Khoury
    Department of Pathology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Adv Anat Pathol 12:212-20. 2005
    ..Current therapy for patients with ESFT includes chemotherapy and surgery with or without radiation therapy. At present, the most significant prognostic factor for patients with ESFT is whether the disease is localized or metastatic...
  2. ncbi request reprint Nephroblastic neoplasms
    Joseph D Khoury
    Department of Pathology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Clin Lab Med 25:341-61, vi-vii. 2005
    ..Nephrogenic rests and a special variant of nephroblastoma, cystic partially differentiated nephroblastoma, also are discussed...
  3. pmc Copy number gains in EGFR and copy number losses in PTEN are common events in osteosarcoma tumors
    Serena S Freeman
    Department of Pathology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Cancer 113:1453-61. 2008
    ..In this study, the authors further analyzed the genomic features of EGFR in osteosarcoma tumors and investigated whether they correlate with phosphatase and tensin homolog (PTEN) expression and copy number status...
  4. ncbi request reprint Telangiectatic osteosarcoma: the St. Jude Children's Research Hospital's experience
    Aaron Weiss
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Cancer 109:1627-37. 2007
    ..Telangiectatic osteosarcoma (TOS) is a rare subtype of osteosarcoma (OS). The authors reviewed their experience with TOS to characterize its histologic, radiologic, and clinical features...
  5. pmc ICAM-2 expression mediates a membrane-actin link, confers a nonmetastatic phenotype and reflects favorable tumor stage or histology in neuroblastoma
    Karina Jin Yoon
    Department of Molecular Pharmacology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    PLoS ONE 3:e3629. 2008
    ..Current work focuses on identifying specific protein domains critical to the regulation of neuroblastoma cell motility and metastasis and on determining if these domains represent exploitable therapeutic targets...
  6. pmc Grading of nonrhabdomyosarcoma soft tissue sarcoma in children and adolescents: a comparison of parameters used for the Fédération Nationale des Centers de Lutte Contre le Cancer and Pediatric Oncology Group Systems
    Joseph D Khoury
    Department of Pathology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Cancer 116:2266-74. 2010
    ..The applicability and prognostic utility of the FNCLCC system in pediatric NRSTS has not been assessed or compared with the POG system...
  7. ncbi request reprint St. Jude Children's Research Hospital, Memphis, Tennessee: gestational choriocarcinoma
    Aaron Weiss
    Department of Hematology Oncology, St Jude Children s Research Hospital, and Department of Radiology, University of Tennessee College of Medicine, Memphis, Tennessee 38105 2794, USA
    Pediatr Blood Cancer 47:640-6. 2006
    ..Key features and findings of the case as well as important management issues will be discussed...
  8. ncbi request reprint Significance of pleural effusion in neuroblastoma
    Himesh Gupta
    Department of Surgery, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Pediatr Blood Cancer 49:906-8. 2007
    ....
  9. ncbi request reprint MRI and biologic behavior of desmoid tumors in children
    M Beth McCarville
    Division of Diagnostic Imaging, Department of Radiological Sciences, St Jude Children s Research Hospital, 332 N Lauderdale St, Memphis, TN 38105 2794, USA
    AJR Am J Roentgenol 189:633-40. 2007
    ..We also aimed to determine how imaging features change during adjuvant treatment and how the imaging features relate to the histologic features...
  10. ncbi request reprint Pharmacologic inhibition of cyclin-dependent kinase 4/6 activity arrests proliferation in myoblasts and rhabdomyosarcoma-derived cells
    Raya Saab
    Department of Hematology Oncology, St Jude Children s Research Hospital, 332 North Lauderdale Street, Memphis, TN 38105, USA
    Mol Cancer Ther 5:1299-308. 2006
    ..Our findings support the concept that pharmacologic inhibition of Cdk4/Cdk6 may represent a useful therapeutic strategy to control cell proliferation and possibly promote myogenic differentiation in rhabdomyosarcoma...
  11. ncbi request reprint Expression and genomic status of EGFR and ErbB-2 in alveolar and embryonal rhabdomyosarcoma
    Ramapriya Ganti
    Department of Pathology and Laboratory Medicine, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Mod Pathol 19:1213-20. 2006
    ..Notably, expression of EGFR correlates with the embryonal subtype, which is also more likely to coexpress EGFR and ErbB-2...
  12. ncbi request reprint Prolactinoma as the first manifestation of Gardner's syndrome
    Geoffrey S Goodin
    Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Pediatr Blood Cancer 50:409-12. 2008
    ..A germline mutation of the APC (adenomatous polyposis coli) gene was identified. Our case illustrates the association between prolactinoma and FAP, which may represent a rare subtype of Gardner's and BTP syndromes...
  13. ncbi request reprint Desmoplastic small round cell tumor in childhood: the St. Jude Children's Research Hospital experience
    Raya Saab
    Department of Hematology Oncology, St Jude Children s Research Hospital, and Department of Surgery, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee 38105 2794, USA
    Pediatr Blood Cancer 49:274-9. 2007
    ..Desmoplastic small round cell tumor (DSRCT) is a rare, primarily intra-abdominal tumor that has a poor outcome with current therapies...
  14. ncbi request reprint Osteosarcoma among children aged 5 years or younger: the St. Jude Children's Research Hospital experience
    Christine M Hartford
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Pediatr Hematol Oncol 28:43-7. 2006
    ..These findings and a review of the similar cases in the literature suggest that osteosarcoma's clinical characteristics are similar among young children and older children...
  15. doi request reprint Predictive factors of invasion in eyes with retinoblastoma enucleated after eye salvage treatments
    Julia Balaguer
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Pediatr Blood Cancer 52:351-6. 2009
    ..The impact of chemotherapy, focal therapies, radiation and co-existing ocular morbidities on histology of eyes with retinoblastoma enucleated following chemoreduction is not well known...
  16. doi request reprint Angiosarcomas arising in the viscera and soft tissue of children and young adults: a clinicopathologic study of 15 cases
    Andrea T Deyrup
    Department of Pathology, Emory University, Atlanta, GA, USA
    Am J Surg Pathol 33:264-9. 2009
    ..Although extremely rare, angiosarcomas do affect children and young adults and this diagnosis should be considered in atypical vascular tumors occurring in the mediastinum and those with brisk mitotic activity and/or necrosis...
  17. ncbi request reprint Ewing sarcoma-family tumors that arise after treatment of primary childhood cancer
    Sheri L Spunt
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Cancer 107:201-6. 2006
    ..ESFT arising as a second cancer was reviewed and characterized at our childhood cancer center...
  18. ncbi request reprint The utility of epithelial membrane antigen and vimentin in the diagnosis of chromophobe renal cell carcinoma
    Joseph D Khoury
    Department of Pathology, Case Western Reserve University University Hospitals of Cleveland, OH, USA
    Ann Diagn Pathol 6:154-8. 2002
    ..Nevertheless, the lack of such an immunophenotype is a reliable indication that a neoplasm under consideration is not CHRCC...
  19. ncbi request reprint Cytogenetic findings in blastoid mantle cell lymphoma
    Joseph D Khoury
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Hum Pathol 34:1022-9. 2003
    ..03). We conclude that blastoid MCL tumors often show complex cytogenetic aberrations. Some abnormalities correlate with morphologic features, suggesting that morphologic variants of blastoid MCL may arise via different molecular pathways...
  20. ncbi request reprint Ewing sarcoma family of tumors: a model for the new era of integrated laboratory diagnostics
    Joseph D Khoury
    Associated Pathologists Chartered Quest Diagnostics, 4230 Burnham Avenue, Las Vegas, NV 89119, USA
    Expert Rev Mol Diagn 8:97-105. 2008
    ..This review will address the features of ESFT and how it has emerged as a model for the new era of integrated diagnostics...
  21. ncbi request reprint A systematic approach to diagnosis of mature T-cell leukemias reveals heterogeneity among WHO categories
    Marco Herling
    Department of Hematopathology, Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Blood 104:328-35. 2004
    ..Our results indicate that incorporation of additional criteria, such as TCL1 expression status and hematologic parameters, can assist in a more accurate classification...
  22. ncbi request reprint Activation status of the JAK/STAT3 pathway in mantle cell lymphoma
    Marwan A Yared
    Department of Hematopathology, The University of Texas, M D Anderson Cancer Center, Houston, USA
    Arch Pathol Lab Med 129:990-6. 2005
    ..Signal transducer and activator of transcription 3 (STAT3) is oncogenic, and we previously found evidence of constitutive STAT3 activation in a relatively small number of frozen mantle cell lymphoma (MCL) cell tumors...