S C Howard

Summary

Affiliation: St. Jude Children's Research Hospital
Country: USA

Publications

  1. ncbi request reprint Treatment for children with severe aplastic anemia and sickle cell disease in low income countries in Latin America: a report on the recent meetings of the Monza International School of Pediatric Hematology/Oncology (MISPHO): Part III
    Scott C Howard
    International Outreach Program and Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Pediatr Blood Cancer 48:598-9. 2007
  2. ncbi request reprint Safety of lumbar puncture for children with acute lymphoblastic leukemia and thrombocytopenia
    S C Howard
    Department of Hematology Oncology, ALSAC Bldg, Room C6005, St Jude Children s Research Hospital, 332 N Lauderdale St, Memphis, TN 38105 2794, USA
    JAMA 284:2222-4. 2000
  3. ncbi request reprint Pitfalls in predicting tumor lysis syndrome
    Scott C Howard
    Department of Hematology Oncology and the International Outreach Program, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    Leuk Lymphoma 47:782-5. 2006
  4. ncbi request reprint Strategies to improve outcomes of children with cancer in low-income countries
    Scott C Howard
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    Eur J Cancer 41:1584-7. 2005
  5. ncbi request reprint Protocol-based treatment for children with cancer in low income countries in Latin America: a report on the recent meetings of the Monza International School of Pediatric Hematology/Oncology (MISPHO)--part II
    Scott C Howard
    International Outreach Program and Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Pediatr Blood Cancer 48:486-90. 2007
  6. ncbi request reprint Improving outcomes for children with cancer in low-income countries in Latin America: a report on the recent meetings of the Monza International School of Pediatric Hematology/Oncology (MISPHO)-Part I
    Scott C Howard
    International Outreach Program and Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Pediatr Blood Cancer 48:364-9. 2007
  7. ncbi request reprint Delays in diagnosis and treatment of childhood cancer: where in the world are they important?
    Scott C Howard
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Pediatr Blood Cancer 44:303-4. 2005
  8. ncbi request reprint Natural history of moderate aplastic anemia in children
    Scott C Howard
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Pediatr Blood Cancer 43:545-51. 2004
  9. ncbi request reprint Childhood cancer epidemiology in low-income countries
    Scott C Howard
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Cancer 112:461-72. 2008
  10. ncbi request reprint Risk factors for traumatic and bloody lumbar puncture in children with acute lymphoblastic leukemia
    Scott C Howard
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN, USA
    JAMA 288:2001-7. 2002

Detail Information

Publications71

  1. ncbi request reprint Treatment for children with severe aplastic anemia and sickle cell disease in low income countries in Latin America: a report on the recent meetings of the Monza International School of Pediatric Hematology/Oncology (MISPHO): Part III
    Scott C Howard
    International Outreach Program and Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Pediatr Blood Cancer 48:598-9. 2007
    ..Appropriate therapy was most likely to occur in MISPHO centers with an active twinning program with a center in a high-income country...
  2. ncbi request reprint Safety of lumbar puncture for children with acute lymphoblastic leukemia and thrombocytopenia
    S C Howard
    Department of Hematology Oncology, ALSAC Bldg, Room C6005, St Jude Children s Research Hospital, 332 N Lauderdale St, Memphis, TN 38105 2794, USA
    JAMA 284:2222-4. 2000
    ..Patients with thrombocytopenia are at risk for spontaneous or procedure-related hemorrhage. Whether such patients can safely undergo lumbar puncture (LP) without prophylactic platelet transfusion is unknown...
  3. ncbi request reprint Pitfalls in predicting tumor lysis syndrome
    Scott C Howard
    Department of Hematology Oncology and the International Outreach Program, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    Leuk Lymphoma 47:782-5. 2006
  4. ncbi request reprint Strategies to improve outcomes of children with cancer in low-income countries
    Scott C Howard
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    Eur J Cancer 41:1584-7. 2005
  5. ncbi request reprint Protocol-based treatment for children with cancer in low income countries in Latin America: a report on the recent meetings of the Monza International School of Pediatric Hematology/Oncology (MISPHO)--part II
    Scott C Howard
    International Outreach Program and Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Pediatr Blood Cancer 48:486-90. 2007
    ..Despite the use of all-trans-retinoic acid during induction for acute promyelocytic leukemia, the incidence of fatal hemorrhage remains unacceptably high...
  6. ncbi request reprint Improving outcomes for children with cancer in low-income countries in Latin America: a report on the recent meetings of the Monza International School of Pediatric Hematology/Oncology (MISPHO)-Part I
    Scott C Howard
    International Outreach Program and Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Pediatr Blood Cancer 48:364-9. 2007
    ..cure4kids.org. Identifying preventable causes of abandonment of therapy and documenting the nutritional status of patients treated at MISPHO centers are areas of active research...
  7. ncbi request reprint Delays in diagnosis and treatment of childhood cancer: where in the world are they important?
    Scott C Howard
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Pediatr Blood Cancer 44:303-4. 2005
  8. ncbi request reprint Natural history of moderate aplastic anemia in children
    Scott C Howard
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Pediatr Blood Cancer 43:545-51. 2004
    ..We evaluated the rate of progression to SAA...
  9. ncbi request reprint Childhood cancer epidemiology in low-income countries
    Scott C Howard
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Cancer 112:461-72. 2008
    ..POND4kids.org), which allows collection, analysis, and sharing of data...
  10. ncbi request reprint Risk factors for traumatic and bloody lumbar puncture in children with acute lymphoblastic leukemia
    Scott C Howard
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN, USA
    JAMA 288:2001-7. 2002
    ..Traumatic or bloody lumbar puncture (LP) reduces the diagnostic value of the procedure and may worsen the outcome of patients with acute lymphoblastic leukemia (ALL). Little is known about the risk factors for traumatic and bloody LP...
  11. ncbi request reprint Endocrine complications in pediatric patients with acute lymphoblastic leukemia
    Scott C Howard
    Department of Hematology Oncology, University of Tennessee Health Science Center, Memphis, TN, USA
    Blood Rev 16:225-43. 2002
    ..Finally, patients who have received 18 or 24Gy of cranial irradiation may have clinical or subclinical deficiencies of thyroid hormones...
  12. pmc Long-term results of St Jude Total Therapy Studies 11, 12, 13A, 13B, and 14 for childhood acute lymphoblastic leukemia
    C H Pui
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Leukemia 24:371-82. 2010
    ..The next main challenge is to further increase cure rates while improving quality of life for all patients...
  13. pmc Increased risk for CNS relapse in pre-B cell leukemia with the t(1;19)/TCF3-PBX1
    S Jeha
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Leukemia 23:1406-9. 2009
    ..These data suggest that with contemporary treatment, patients with the t(1;19) and TCF3/PBX1 fusion have a favorable overall outcome but increased risk of CNS relapse...
  14. ncbi request reprint Premedication with acetaminophen or diphenhydramine for transfusion with leucoreduced blood products in children
    Robert P Sanders
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN, USA
    Br J Haematol 130:781-7. 2005
    ..Febrile and allergic transfusion reactions were rare in paediatric patients transfused with leucoreduced, irradiated blood products, whether premedication was used or not...
  15. pmc ETV6-RUNX1-positive childhood acute lymphoblastic leukemia: improved outcome with contemporary therapy
    D Bhojwani
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Leukemia 26:265-70. 2012
    ....
  16. pmc Clinical consequences of hyperglycemia during remission induction therapy for pediatric acute lymphoblastic leukemia
    J R Roberson
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Leukemia 23:245-50. 2009
    ..Pediatric patients with or without hyperglycemia during remission induction for ALL have similar clinical outcome. Occurrence of hyperglycemia does not warrant alteration of the antileukemic regimen...
  17. pmc Efficacy of high-dose methotrexate, ifosfamide, etoposide and dexamethasone salvage therapy for recurrent or refractory childhood malignant lymphoma
    J T Sandlund
    Department of Oncology, St Jude Children s Research Hospital, University of Tennessee, Memphis, TN, USA
    Ann Oncol 22:468-71. 2011
    ..Children with recurrent or refractory malignant lymphoma generally have a poor prognosis. There is a need for new active drug combinations for this high-risk group of patients...
  18. ncbi request reprint Urolithiasis in pediatric patients with acute lymphoblastic leukemia
    S C Howard
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Leukemia 17:541-6. 2003
    ..05). Seven patients (35%) had recurrent urolithiasis. Patients with ALL are at risk of developing calcium renal stones during chemotherapy, especially when a glucocorticoid is included...
  19. ncbi request reprint Overt testicular disease at diagnosis of childhood acute lymphoblastic leukemia: lack of therapeutic role of local irradiation
    N Hijiya
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    Leukemia 19:1399-403. 2005
    ..In conclusion, the prognostic impact of overt testicular disease has diminished. Irradiation appears to provide no survival advantage to this patient population...
  20. ncbi request reprint Hepatic veno-occlusive disease in children undergoing bone-marrow transplantation: usefulness of sonographic findings
    M B McCarville
    Department of Diagnostic Imaging, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    Pediatr Radiol 31:102-5. 2001
    ..Reports of the usefulness of ultrasonography in the diagnosis of hepatic veno-occlusive disease (HVOD) have presented conflicting results...
  21. doi request reprint Diabetic ketoacidosis during therapy for pediatric acute lymphoblastic leukemia
    Jessica R Roberson
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Pediatr Blood Cancer 50:1207-12. 2008
    ..Hyperglycemia is common during therapy for acute lymphoblastic leukemia (ALL), but diabetic ketoacidosis (DKA) occurs rarely. Morbidity due to DKA in children with ALL has not been systematically studied...
  22. ncbi request reprint Pulmonary alveolar proteinosis in pediatric leukemia
    Hiroto Inaba
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Pediatr Blood Cancer 51:66-70. 2008
    ..Only isolated cases of PAP have been reported, and pediatric experience is limited...
  23. doi request reprint Current management and challenges of malignant disease in the CNS in paediatric leukaemia
    Ching Hon Pui
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38015 2794, USA
    Lancet Oncol 9:257-68. 2008
    ..Perhaps the most formidable challenge is to treat children with CNS relapse after a short initial remission or cranial irradiation...
  24. ncbi request reprint Acute neurocognitive response to methylphenidate among survivors of childhood cancer: a randomized, double-blind, cross-over trial
    Heather M Conklin
    St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    J Pediatr Psychol 32:1127-39. 2007
    ..To investigate the acute efficacy and adverse side effects of methylphenidate (MPH) among survivors of childhood cancer [acute lymphoblastic leukemia (ALL) or brain tumor (BT)] with learning impairments...
  25. ncbi request reprint Baseline mannose binding lectin levels may not predict infection among children with leukemia
    Jeffrey E Rubnitz
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Pediatr Blood Cancer 50:866-8. 2008
    ..Additional studies are required to determine whether serial MBL measurements may be valuable for this purpose...
  26. doi request reprint Effect of race on the outcome of pediatric patients with Hodgkin's lymphoma
    Monika L Metzger
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    J Clin Oncol 26:1282-8. 2008
    ..We examine the effects of race on clinical outcomes among children with Hodgkin's lymphoma (HL) treated with contemporary therapy at a tertiary care children's hospital...
  27. pmc Baseline status of paediatric oncology care in ten low-income or mid-income countries receiving My Child Matters support: a descriptive study
    Raul C Ribeiro
    Department of Oncology and International Outreach Program, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Lancet Oncol 9:721-9. 2008
    ..We aimed to assess baseline status of paediatric cancer care in ten countries that were receiving support (Bangladesh, Egypt, Honduras, Morocco, the Philippines, Senegal, Tanzania, Ukraine, Venezuela, and Vietnam)...
  28. pmc Growth effects of methylphenidate among childhood cancer survivors: a 12-month case-matched open-label study
    Bruce W Jasper
    Division of Behavioral Medicine, University of Tennessee, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Pediatr Blood Cancer 52:39-43. 2009
    ..To investigate the effect of stimulant medication [methylphenidate (MPH)] on growth patterns among survivors of childhood cancer (acute lymphoblastic leukemia or brain tumor)...
  29. pmc Improved prognosis for older adolescents with acute lymphoblastic leukemia
    Ching Hon Pui
    St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Clin Oncol 29:386-91. 2011
    ..We reviewed the outcome of older adolescents (age 15 to 18 years) treated in four consecutive Total Therapy studies to determine if recent improved treatment extended to this high-risk group...
  30. pmc Changes in medical care at a pediatric oncology referral center after placement of a do-not-resuscitate order
    Justin N Baker
    Department of Pediatric Medicine, Division of Palliative and End of Life Care, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    J Palliat Med 13:1349-52. 2010
    ..We therefore assessed medical care that was continued, added, and discontinued after a DNR order was placed in the medical record...
  31. pmc Long-term efficacy of methylphenidate in enhancing attention regulation, social skills, and academic abilities of childhood cancer survivors
    Heather M Conklin
    Department of Psychology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    J Clin Oncol 28:4465-72. 2010
    ..Methylphenidate (MPH) ameliorates attention problems experienced by some cancer survivors in the short term, but its long-term efficacy is unproven...
  32. pmc Initial response to salvage therapy determines prognosis in relapsed pediatric Hodgkin lymphoma patients
    Monika L Metzger
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Cancer 116:4376-84. 2010
    ..Pediatric Hodgkin lymphoma (HL) is a highly curable disease; however, prognostic factors for the survival of patients who develop recurrent disease have not been clearly defined...
  33. ncbi request reprint 18F-FDG-avid sites mimicking active disease in pediatric Hodgkin's
    Sue C Kaste
    St Jude Children s Research Hospital, Department of Radiological Sciences, University of Tennessee College of Medicine, 332 N Lauderdale, Memphis, TN 38105, USA
    Pediatr Radiol 35:141-54. 2005
    ..It is essential for radiologists to be familiar with these findings in order to stage disease activity and therapeutic response accurately...
  34. pmc Conservative management of pancreatic pseudocysts in children with acute lymphoblastic leukemia
    Holly L Spraker
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Pediatr Hematol Oncol 31:957-9. 2009
    ..In addition, these patients demonstrate that oral feeding can be initiated after the acute episode of pancreatitis resolves even if a pseudocyst is present...
  35. pmc Effect of allopurinol versus urate oxidase on methotrexate pharmacokinetics in children with newly diagnosed acute lymphoblastic leukemia
    Kristine R Crews
    Department of Pharmaceutical Sciences, St Jude Children s Research Hospital, Memphis, TN 38105 3678, USA
    Cancer 116:227-32. 2010
    ....
  36. pmc High-risk childhood acute lymphoblastic leukemia
    Deepa Bhojwani
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    Clin Lymphoma Myeloma 9:S222-30. 2009
    ..Genome-wide interrogation of leukemic cell genetic abnormalities and germline genetic variations promise to identify new molecular targets for therapy...
  37. pmc Side effects of methylphenidate in childhood cancer survivors: a randomized placebo-controlled trial
    Heather M Conklin
    Divisionsof Behavioral Medicine, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Pediatrics 124:226-33. 2009
    ..To investigate the frequency and severity of side effects of methylphenidate among childhood survivors of acute lymphoblastic leukemia and brain tumors and identify predictors of higher adverse effect levels...
  38. pmc Treating childhood acute lymphoblastic leukemia without cranial irradiation
    Ching Hon Pui
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    N Engl J Med 360:2730-41. 2009
    ..Prophylactic cranial irradiation has been a standard treatment in children with acute lymphoblastic leukemia (ALL) who are at high risk for central nervous system (CNS) relapse...
  39. ncbi request reprint A revised classification scheme for acute transfusion reactions
    Robert P Sanders
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Transfusion 47:621-8. 2007
    ..Consequently, its use to classify individual reactions can result in significant inter- and intraobserver variability, which can complicate patient management and clinical research...
  40. pmc Acetaminophen and diphenhydramine premedication for allergic and febrile nonhemolytic transfusion reactions: good prophylaxis or bad practice?
    Terrence L Geiger
    Department of Pathology and Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Transfus Med Rev 21:1-12. 2007
    ....
  41. ncbi request reprint Establishment of ethical oversight of human research in El Salvador: lessons learned
    Miguela A Caniza
    St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Lancet Oncol 7:1027-33. 2006
    ..This model of interaction can also be used by institutions in high-income countries to create and strengthen the capacity for ethics in human research in low-income countries...
  42. ncbi request reprint Risk of adverse events after completion of therapy for childhood acute lymphoblastic leukemia
    Ching Hon Pui
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    J Clin Oncol 23:7936-41. 2005
    ..Our goal was to use the information to further refine therapy and advance cure rates...
  43. ncbi request reprint Patterns of treatment failure in pediatric and young adult patients with Hodgkin's disease: local disease control with combined-modality therapy
    Matthew J Krasin
    Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Clin Oncol 23:8406-13. 2005
    ..This study defines the cumulative incidence (CI) of local failure (LF) and prognostic factors for pediatric patients treated for HD with combined-modality therapy (CMT)...
  44. ncbi request reprint Unsafe and violent behavior in commercials aired during televised major sporting events
    Robert F Tamburro
    Division of Critical Care Medicine, St Jude Children s Research Hospital, and Le Bonheur Children s Medical Center, 332 North Lauderdale, Memphis, Tennessee 38105 2784, USA
    Pediatrics 114:e694-8. 2004
    ..The objective of this study was to determine the proportion of commercials that depict violence or other unsafe behavior during major televised sporting events that are aired before 9:00 pm...
  45. pmc Smaller white-matter volumes are associated with larger deficits in attention and learning among long-term survivors of acute lymphoblastic leukemia
    Wilburn E Reddick
    Division of Translational Imaging Research, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Cancer 106:941-9. 2006
    ..The primary objective of this study was to test the hypothesis that survivors of childhood acute lymphoblastic leukemia (ALL) have deficits in neurocognitive performance, and smaller white-matter volumes are associated with these deficits...
  46. ncbi request reprint Utility of automated counting to determine absolute neutrophil counts and absolute phagocyte counts for pediatric cancer treatment protocols
    Nobuko Hijiya
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Cancer 101:2681-6. 2004
    ..By analyzing blood samples from children undergoing cancer treatment, the authors determined whether ANCs and APCs obtained by automated methods correlated positively with ANCs and APCs obtained manually...
  47. ncbi request reprint Severe cardiopulmonary complications consistent with systemic inflammatory response syndrome caused by leukemia cell lysis in childhood acute myelomonocytic or monocytic leukemia
    Nobuko Hijiya
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Pediatr Blood Cancer 44:63-9. 2005
    ..Life-threatening pulmonary complications that coincide with cell lysis during early chemotherapy and that mimic systemic inflammatory response syndrome (SIRS) have been reported in patients with acute myeloid leukemia (AML)...
  48. ncbi request reprint Improved outcome for children with acute lymphoblastic leukemia: results of Total Therapy Study XIIIB at St Jude Children's Research Hospital
    Ching Hon Pui
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    Blood 104:2690-6. 2004
    ..01% or more at the end of the 6-week remission induction phase. Our results suggest the efficacy of early intensification of intrathecal chemotherapy and provide the basis for studies omitting cranial irradiation altogether...
  49. ncbi request reprint White race as a risk factor for hypothyroidism after treatment for pediatric Hodgkin's lymphoma
    Monika L Metzger
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    J Clin Oncol 24:1516-21. 2006
    ..The aim of this study was to determine whether race is an independent risk factor for hypothyroidism in survivors of pediatric Hodgkin's lymphoma...
  50. ncbi request reprint Results of therapy for acute lymphoblastic leukemia in black and white children
    Ching Hon Pui
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    JAMA 290:2001-7. 2003
    ..Treatment results for acute lymphoblastic leukemia (ALL) clearly have improved over the past decade, but black children have not fared as well as white children in large national trials...
  51. ncbi request reprint Pharmacokinetics of 2-chlorodeoxyadenosine in a child undergoing hemofiltration and hemodialysis for acute renal failure
    Kristine R Crews
    Department of Pharmaceutical Sciences, St Jude Children s Research Hospital, 332 N Lauderdale, Memphis, TN 38105 2794, USA
    J Pediatr Hematol Oncol 24:677-80. 2002
    ..More experience in the administration of 2-CdA to patients with renal insufficiency will be necessary to determine the need for dosage adjustment...
  52. pmc Body mass index does not influence pharmacokinetics or outcome of treatment in children with acute lymphoblastic leukemia
    Nobuko Hijiya
    Department of Oncology, St Jude Children s Research Hospital, 332 North Lauderdale St, Memphis, TN 38105 2794, USA
    Blood 108:3997-4002. 2006
    ..Further, the systemic clearance of methotrexate, teniposide, etoposide, and cytarabine did not differ with BMI (P > .3). We conclude that BMI does not affect the outcome or toxicity of chemotherapy in this patient population with ALL...
  53. pmc Prognostic significance of CD20 expression in childhood B-cell precursor acute lymphoblastic leukemia
    Sima Jeha
    Department of Hematology Oncology, St Jude Children s Research Hospital, 332 N Lauderdale St, Memphis, TN 38105, USA
    Blood 108:3302-4. 2006
    ..9% versus 78% +/- 3.1% (P = .08). These data suggest that CD20 expression is not associated with inferior outcome in pediatric patients treated with contemporary regimens...
  54. ncbi request reprint Implementation of a data management program in a pediatric cancer unit in a low income country
    Lisa Ayoub
    International Outreach Program, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Pediatr Blood Cancer 49:23-7. 2007
    ....
  55. ncbi request reprint Outcome of childhood acute lymphoblastic leukaemia in resource-poor countries
    Monika L Metzger
    Department of Hematology Oncology and International Outreach Program, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    Lancet 362:706-8. 2003
    ..Outcome could be substantially improved by interventions that help to prevent abandonment of therapy (such as funding for transport, satellite clinics, and support groups), and by prompt treatment of infection...
  56. ncbi request reprint Pericardial involvement at diagnosis in pediatric Hodgkin lymphoma patients
    Hamid Bashir
    Departments of Internal Medicine and Pediatrics, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    Pediatr Blood Cancer 49:666-71. 2007
    ..Because most cases are clinically silent, the incidence, clinical course, and outcome of pericardial involvement in Hodgkin lymphoma are unknown...
  57. ncbi request reprint Establishment of a pediatric oncology program and outcomes of childhood acute lymphoblastic leukemia in a resource-poor area
    Scott C Howard
    Department of Hematology Oncology and the International Outreach Program, St Jude Children s Research Hospital, Memphis, Tenn
    JAMA 291:2471-5. 2004
    ..The cure rate for childhood acute lymphoblastic leukemia (ALL) differs markedly between developed and developing countries...
  58. ncbi request reprint Femoral head osteonecrosis in pediatric and young adult patients with leukemia or lymphoma
    Evguenia J Karimova
    Department of Radiological Sciences, Division of Diagnostic Imaging and Biostatistics, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    J Clin Oncol 25:1525-31. 2007
    ..We determined clinical and imaging risk factors predicting clinical joint outcomes of femoral head osteonecrosis in pediatric patients with leukemia or lymphoma...
  59. ncbi request reprint Natural history of thyroid nodules in survivors of pediatric Hodgkin lymphoma
    Monika L Metzger
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee
    Pediatr Blood Cancer 46:314-9. 2006
    ..Ultrasonography provides an inexpensive and non-invasive method of thyroid screening, but the clinical significance of thyroid nodules detected by ultrasound screening is uncertain...
  60. doi request reprint Safety of central venous catheter placement at diagnosis of acute lymphoblastic leukemia in children
    G Gonzalez
    Department of Surgery, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Pediatr Blood Cancer 58:498-502. 2012
    ..We sought to determine whether early placement in children with acute lymphoblastic leukemia (ALL), a group at high risk for infection and thrombosis, was associated with an increased rate of surgical complications...
  61. ncbi request reprint Itraconazole-enhanced chemotherapy toxicity in a patient with Hodgkin lymphoma
    Hamid Bashir
    Department of Internal Medicine, University of Tennessee Health Science Center, Memphis, 38105, USA
    J Pediatr Hematol Oncol 28:33-5. 2006
    ..Appropriate care should be exercised when combining cancer chemotherapy with cytochrome P450 and P-glycoprotein inhibitors, such as itraconazole...
  62. doi request reprint Correlation of bone age, dental age, and chronological age in survivors of childhood acute lymphoblastic leukaemia
    Mary Beth Martin
    Department of Orthodontics, University of Tennessee Health Science Center, Memphis, TN 38105 2794, USA
    Int J Paediatr Dent 18:217-23. 2008
    ..There is little information about oncotherapy-related dental development in childhood acute lymphoblastic leukaemia (ALL)...
  63. ncbi request reprint MRI of knee osteonecrosis in children with leukemia and lymphoma: Part 2, clinical and imaging patterns
    Evguenia J Karimova
    Department of Radiological Sciences, Division of Diagnostic Imaging, St Jude Children s Research Hospital, 332 N Lauderdale St, Memphis, TN 38105, USA
    AJR Am J Roentgenol 186:477-82. 2006
    ..Such information is important for early diagnosis of this frequent complication and for choosing an appropriate treatment strategy...
  64. ncbi request reprint Association between tea ingestion and invasive Bacillus cereus infection among children with cancer
    C M El Saleeby
    Department of Infectious Diseases, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Clin Infect Dis 39:1536-9. 2004
    ..cereus bacteremia. Policies designed to interrupt transmission of this pathogen to susceptible patients should be considered...
  65. pmc Severe thrombocytopenia with iron deficiency anemia
    Van K Morris
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Pediatr Hematol Oncol 27:413-9. 2010
    ..The literature exploring the mechanism behind the current clinical findings is reviewed...
  66. doi request reprint Comparison of gallium and PET scans at diagnosis and follow-up of pediatric patients with Hodgkin lymphoma
    Melissa Hines-Thomas
    University of Tennessee School of Medicine, Memphis, Tennessee, USA
    Pediatr Blood Cancer 51:198-203. 2008
    ..Positron emission tomography (PET) and gallium scans facilitate diagnosis and staging, evaluation of response to therapy, and monitoring for relapse in Hodgkin lymphoma (HL), but have not been compared in pediatric HL...
  67. ncbi request reprint Abdominal compartment syndrome in a newly diagnosed patient with Burkitt lymphoma
    Jennifer M Hendrick
    Department of Radiological Sciences, St Jude Children s Research Hospital, 332 N Lauderdale, Memphis, TN 38105 2794, USA
    Pediatr Radiol 36:254-7. 2006
    ..We present the radiological and clinical aspects of a patient with advanced-stage Burkitt lymphoma who presented with an acute abdomen complicated by abdominal compartment syndrome...
  68. pmc Management of occlusion and thrombosis associated with long-term indwelling central venous catheters
    Jacquelyn L Baskin
    Department of Oncology and International Outreach Program, St Jude Children s Research Hospital, Memphis, TN 3105 2794, USA
    Lancet 374:159-69. 2009
    ..Prevention of catheter-related thromboses includes proper positioning of the CVC and prevention of infections; anticoagulation prophylaxis is not currently recommended...
  69. ncbi request reprint Comparison of treatment outcomes of childhood Hodgkin lymphoma in two US centers and a center in Recife, Brazil
    Saunders C Hsu
    Department of Pediatrics, Division of Pediatric Hematology Oncology, Doernbecher Children s Hospital, Oregon Health and Science University, Portland, Oregon, USA
    Pediatr Blood Cancer 49:139-44. 2007
    ..Pediatric Hodgkin lymphoma (HL) has a cure rate of more than 80% in high-income countries (HIC). However, more than 80% of the world's children live in low-income countries (LIC), where the cure rate is often much lower...
  70. ncbi request reprint Impact of an education program on late diagnosis of retinoblastoma in Honduras
    Christopher Leander
    Weill Cornell Medical College, New York, New York, USA
    Pediatr Blood Cancer 49:817-9. 2007
    ..Early diagnosis is necessary to improve the survival of children with retinoblastoma in these countries...
  71. doi request reprint Changes in outcomes (1996-2004) for pediatric oncology and hematopoietic stem cell transplant patients requiring invasive mechanical ventilation
    Robert F Tamburro
    Penn State Children s Hospital, Pennsylvania State University College of Medicine, Milton S Hersey Medical Center, Hersey, PA, USA
    Pediatr Crit Care Med 9:270-7. 2008
    ....