Research Topics
| N HijiyaSummaryAffiliation: St. Jude Children's Research Hospital Country: USA Publications
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Detail Information
Publications
Low-dose oral etoposide-based induction regimen for children with acute lymphoblastic leukemia in first bone marrow relapseN Hijiya
Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
Leukemia 18:1581-6. 2004..0+/-9.6% for those with late relapse and 20.0+/-8.0% for those with early relapse. We conclude that low-dose etoposide administered orally has a cytoreductive effect in relapsed ALL...
Severe cardiopulmonary complications consistent with systemic inflammatory response syndrome caused by leukemia cell lysis in childhood acute myelomonocytic or monocytic leukemiaNobuko Hijiya
Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
Pediatr Blood Cancer 44:63-9. 2005..Life-threatening pulmonary complications that coincide with cell lysis during early chemotherapy and that mimic systemic inflammatory response syndrome (SIRS) have been reported in patients with acute myeloid leukemia (AML)...
Utility of automated counting to determine absolute neutrophil counts and absolute phagocyte counts for pediatric cancer treatment protocolsNobuko Hijiya
Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
Cancer 101:2681-6. 2004..By analyzing blood samples from children undergoing cancer treatment, the authors determined whether ANCs and APCs obtained by automated methods correlated positively with ANCs and APCs obtained manually...
Overt testicular disease at diagnosis of childhood acute lymphoblastic leukemia: lack of therapeutic role of local irradiationN Hijiya
Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
Leukemia 19:1399-403. 2005..In conclusion, the prognostic impact of overt testicular disease has diminished. Irradiation appears to provide no survival advantage to this patient population...
Cumulative incidence of secondary neoplasms as a first event after childhood acute lymphoblastic leukemiaNobuko Hijiya
Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
JAMA 297:1207-15. 2007..Little is known about the incidence of secondary neoplasms after 15 to 20 years in children and adolescents who were treated for acute lymphoblastic leukemia...
Body mass index does not influence pharmacokinetics or outcome of treatment in children with acute lymphoblastic leukemiaNobuko Hijiya
Department of Oncology, St Jude Children s Research Hospital, 332 North Lauderdale St, Memphis, TN 38105 2794, USA
Blood 108:3997-4002. 2006..Further, the systemic clearance of methotrexate, teniposide, etoposide, and cytarabine did not differ with BMI (P > .3). We conclude that BMI does not affect the outcome or toxicity of chemotherapy in this patient population with ALL...
Effective treatment of advanced-stage childhood lymphoblastic lymphoma without prophylactic cranial irradiation: results of St Jude NHL13 studyJ T Sandlund
Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
Leukemia 23:1127-30. 2009..The treatment described here produces high cure rates in children with lymphoblastic lymphoma without the use of prophylactic cranial irradiation...
Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia after first relapseE Coustan-Smith
Department of Hematology-Oncology, Children's Research Hospital, Memphis, TN, USA
Leukemia 18:499-504. 2004..We conclude that MRD assays should be used to guide the selection of postremission therapy in patients with ALL in first relapse...
Comparison of native E. coli and PEG asparaginase pharmacokinetics and pharmacodynamics in pediatric acute lymphoblastic leukemiaJ C Panetta
Department of Pharmaceutical Sciences, St Jude Children s Research Hospital, Memphis, Tennessee, USA
Clin Pharmacol Ther 86:651-8. 2009..At relapse, there were significant pharmacokinetic and pharmacodynamic differences attributable to ASP preparation and antibody status...
Successive clinical trials for childhood acute myeloid leukemia at St Jude Children's Research Hospital, from 1980 to 2000R C Ribeiro
Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
Leukemia 19:2125-9. 2005..We conclude that subtype-specific therapies are needed to replace the 'one size fits all' strategy of the past two decades...
Risk of adverse events after completion of therapy for childhood acute lymphoblastic leukemiaChing Hon Pui
Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
J Clin Oncol 23:7936-41. 2005..Our goal was to use the information to further refine therapy and advance cure rates...
Patient-reported outcomes in end-of-life research in pediatric oncologyPamela S Hinds
St Jude Children s Research Hospital, Memphis, TN 38105 2719, USA
J Pediatr Psychol 32:1079-88. 2007....
Phase II study of topotecan in combination with dexamethasone, asparaginase, and vincristine in pediatric patients with acute lymphoblastic leukemia in first relapseNobuko Hijiya
Department of Oncology, St Jude Children s Research Hospital, Memphis, TN, USA
Cancer 112:1983-91. 2008..The authors evaluated the response rate, toxicity, and pharmacokinetics of topotecan given before standard induction therapy for childhood acute lymphoblastic leukemia (ALL) in first relapse...
Lack of benefit of early detection of relapse after completion of therapy for acute lymphoblastic leukemiaJeffrey E Rubnitz
Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
Pediatr Blood Cancer 44:138-41. 2005..We therefore sought to determine if detection of relapse by blood counts before the onset of symptoms provided any clinical benefit...
Prognostic significance of CD20 expression in childhood B-cell precursor acute lymphoblastic leukemiaSima Jeha
Department of Hematology Oncology, St Jude Children s Research Hospital, 332 N Lauderdale St, Memphis, TN 38105, USA
Blood 108:3302-4. 2006..9% versus 78% +/- 3.1% (P = .08). These data suggest that CD20 expression is not associated with inferior outcome in pediatric patients treated with contemporary regimens...
Ancestry and pharmacogenetics of antileukemic drug toxicityShinji Kishi
Department of Pharmaceutical Sciences, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
Blood 109:4151-7. 2007..026). The genotype-phenotype associations were similar whether analyses were adjusted by self-reported race or ancestry-informative genetic markers. Germ-line polymorphisms are significant determinants of toxicity of antileukemic therapy...
