Kathleen J Helton

Summary

Affiliation: St. Jude Children's Research Hospital
Country: USA

Publications

  1. doi request reprint Diffusion tensor imaging of brainstem tumors: axonal degeneration of motor and sensory tracts
    Kathleen J Helton
    Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    J Neurosurg Pediatr 1:270-6. 2008
  2. doi request reprint Arterial spin-labeled perfusion combined with segmentation techniques to evaluate cerebral blood flow in white and gray matter of children with sickle cell anemia
    Kathleen J Helton
    Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Pediatr Blood Cancer 52:85-91. 2009
  3. ncbi request reprint Neuroimaging-detected late transient treatment-induced lesions in pediatric patients with brain tumors
    Kathleen J Helton
    Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, Tennesee 38105 2794, USA
    J Neurosurg 102:179-86. 2005
  4. ncbi request reprint Medullomyoblastoma: a radiographic and clinicopathologic analysis of six cases and review of the literature
    Kathleen J Helton
    Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    Cancer 101:1445-54. 2004
  5. ncbi request reprint Medulloblastoma metastatic to the suprasellar region at diagnosis: a report of six cases with clinicopathologic correlation
    Kathleen J Helton
    St Jude Children s Research Hospital, Semmes Murphy Clinic, Memphis, TN 38105, USA
    Pediatr Neurosurg 37:111-7. 2002
  6. pmc Hemodynamic responses to visual stimulation in children with sickle cell anemia
    Ping Zou
    Department of Radiological Sciences, St Jude Children s Research Hospital, MS 220, 262 Danny Thomas Place, Memphis, TN 38105, USA
    Brain Imaging Behav 5:295-306. 2011
  7. pmc Sequencing of local therapy affects the pattern of treatment failure and survival in children with atypical teratoid rhabdoid tumors of the central nervous system
    Atmaram S Pai Panandiker
    Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, TN, USA
    Int J Radiat Oncol Biol Phys 82:1756-63. 2012
  8. ncbi request reprint Diffusion tensor imaging of intraaxial tumors at the cervicomedullary and pontomedullary junctions. Report of two cases
    Nicholas S Phillips
    Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    J Neurosurg 103:557-62. 2005
  9. pmc Computer-aided detection of therapy-induced leukoencephalopathy in pediatric acute lymphoblastic leukemia patients treated with intravenous high-dose methotrexate
    John O Glass
    Division of Translational Imaging Research, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Magn Reson Imaging 24:785-91. 2006
  10. ncbi request reprint Chromosome 17 abnormalities in pediatric neuroblastic tumor with abundant neuropil and true rosettes
    Christine Fuller
    Department of Pathology, St Jude Children s, Research Hospital, Memphis, TN, USA
    Am J Clin Pathol 126:277-83. 2006

Detail Information

Publications32

  1. doi request reprint Diffusion tensor imaging of brainstem tumors: axonal degeneration of motor and sensory tracts
    Kathleen J Helton
    Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    J Neurosurg Pediatr 1:270-6. 2008
    ..The authors sought to determine whether DT imaging and white matter tractography could detect axonal degeneration in patients with brainstem tumors...
  2. doi request reprint Arterial spin-labeled perfusion combined with segmentation techniques to evaluate cerebral blood flow in white and gray matter of children with sickle cell anemia
    Kathleen J Helton
    Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Pediatr Blood Cancer 52:85-91. 2009
    ..Recent studies have documented elevated gray matter (GM) CBF in untreated children with SCA, but no measurements of white matter (WM) CBF have been reported...
  3. ncbi request reprint Neuroimaging-detected late transient treatment-induced lesions in pediatric patients with brain tumors
    Kathleen J Helton
    Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, Tennesee 38105 2794, USA
    J Neurosurg 102:179-86. 2005
    ..Although late-delayed reactions are thought to be permanent, in this study the authors sought to characterize transient brain lesions (TBLs) in the late-delayed period that completely resolved without imaging or neurological sequelae...
  4. ncbi request reprint Medullomyoblastoma: a radiographic and clinicopathologic analysis of six cases and review of the literature
    Kathleen J Helton
    Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    Cancer 101:1445-54. 2004
    ..Medullomyoblastoma (MMB) is a rare cerebellar embryonal neoplasm that occurs almost exclusively in children. It is biphasic by microscopy, containing myoblastic and primitive neuroectodermal components...
  5. ncbi request reprint Medulloblastoma metastatic to the suprasellar region at diagnosis: a report of six cases with clinicopathologic correlation
    Kathleen J Helton
    St Jude Children s Research Hospital, Semmes Murphy Clinic, Memphis, TN 38105, USA
    Pediatr Neurosurg 37:111-7. 2002
    ..8%. Patients with tumors that show large cell/anaplastic features may be at higher risk for early metastatic involvement of this unusual site...
  6. pmc Hemodynamic responses to visual stimulation in children with sickle cell anemia
    Ping Zou
    Department of Radiological Sciences, St Jude Children s Research Hospital, MS 220, 262 Danny Thomas Place, Memphis, TN 38105, USA
    Brain Imaging Behav 5:295-306. 2011
    ..8, pā€‰ ā‰¤ ā€‰0.05) with Wechsler Abbreviated Scale of Intelligence scores, suggesting that fMRI may help clarify medical, hemodynamic, and neural factors that mediate adverse effects of SCA on neurocognitive function...
  7. pmc Sequencing of local therapy affects the pattern of treatment failure and survival in children with atypical teratoid rhabdoid tumors of the central nervous system
    Atmaram S Pai Panandiker
    Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, TN, USA
    Int J Radiat Oncol Biol Phys 82:1756-63. 2012
    ..To assess the pattern of treatment failure associated with current therapeutic paradigms for childhood atypical teratoid rhabdoid tumors (AT/RT)...
  8. ncbi request reprint Diffusion tensor imaging of intraaxial tumors at the cervicomedullary and pontomedullary junctions. Report of two cases
    Nicholas S Phillips
    Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    J Neurosurg 103:557-62. 2005
    ....
  9. pmc Computer-aided detection of therapy-induced leukoencephalopathy in pediatric acute lymphoblastic leukemia patients treated with intravenous high-dose methotrexate
    John O Glass
    Division of Translational Imaging Research, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Magn Reson Imaging 24:785-91. 2006
    ....
  10. ncbi request reprint Chromosome 17 abnormalities in pediatric neuroblastic tumor with abundant neuropil and true rosettes
    Christine Fuller
    Department of Pathology, St Jude Children s, Research Hospital, Memphis, TN, USA
    Am J Clin Pathol 126:277-83. 2006
    ..No deletions of INI1 or amplifications of MYC or MYCN were detected. This report adds 2 cases to our experience of PNTANTR and is the first to demonstrate isochromosome 17q, a molecular alteration typical of medulloblastomas...
  11. pmc A quantitative MR imaging assessment of leukoencephalopathy in children treated for acute lymphoblastic leukemia without irradiation
    Wilburn E Reddick
    Division of Translational Imaging Research, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    AJNR Am J Neuroradiol 26:2371-7. 2005
    ..The purpose of this study was to use objective quantitative MR imaging to prospectively assess the temporal evolution of LE extent and intensity...
  12. ncbi request reprint Abnormal hippocampal development in children with medulloblastoma treated with risk-adapted irradiation
    Bonnie J Nagel
    Division of Behavioral Medicine, St Jude Children s Research Hospital, Memphis, TN, USA
    AJNR Am J Neuroradiol 25:1575-82. 2004
    ..Therefore, we hypothesized that longitudinal hippocampal volume measurements are abnormal in patients with medulloblastoma and thereby provide a possible substrate for explaining memory dysfunction...
  13. ncbi request reprint Brain injury in children with sickle cell disease: prevalence and etiology
    R Grant Steen
    Department of Diagnostic Imaging, St Jude Children s Research Hospital, Memphis, TN, USA
    Ann Neurol 54:564-72. 2003
    ..The degree of vasculopathy is closely related to the degree of brain injury, implying that vasculopathy is prodromal to most forms of brain injury in hemoglobin SS...
  14. ncbi request reprint Brain imaging findings in pediatric patients with sickle cell disease
    R Grant Steen
    Department of Diagnostic Imaging, St Jude Children s Research Hosp, 332 N Lauderdale St, Memphis, TN 38105 2794, USA
    Radiology 228:216-25. 2003
    ..To determine prevalence of imaging abnormalities in the brain of children with sickle cell disease (SCD) and to identify clinical and methodological factors that influence prevalence estimate...
  15. ncbi request reprint A phase II study of the farnesyl transferase inhibitor, tipifarnib, in children with recurrent or progressive high-grade glioma, medulloblastoma/primitive neuroectodermal tumor, or brainstem glioma: a Children's Oncology Group study
    Maryam Fouladi
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Cancer 110:2535-41. 2007
    ....
  16. ncbi request reprint Brain parenchymal damage after haematopoietic stem cell transplantation for severe sickle cell disease
    Paul Woodard
    Department of Hematology Oncology, St Jude Children s Research Hospital, 332 N Lauderdale Street, Lauderdale, Memphis, TN 38105, USA
    Br J Haematol 129:550-2. 2005
    ..Transient changes occurred early in two patients. Persistent changes occurred in five. Parenchymal lesions occurred in zero of two patients without prior lacunae or infarcts and in all seven with prior lacunae or infarcts (P = 0.0278)...
  17. pmc Prevalence of leukoencephalopathy in children treated for acute lymphoblastic leukemia with high-dose methotrexate
    Wilburn E Reddick
    Division of Translational Imaging Research, Department of Radiological Sciences, St Jude Children s Research Hospital, 332 N Lauderdale Street, Memphis, TN 38105 2794, USA
    AJNR Am J Neuroradiol 26:1263-9. 2005
    ..The purpose of this study was to use objective quantitative MR imaging to prospectively assess potential risk factors on the temporal evolution of LE in patients treated for ALL...
  18. ncbi request reprint The effect of hydroxyurea on vasculopathy in a child with sickle cell disease
    Kathleen J Helton
    Department of Diagnostic Imaging, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    AJNR Am J Neuroradiol 23:1692-6. 2002
    ..Hydroxyurea can be effective in treating vasculopathy, but it might not prevent the progression of parenchymal damage in advanced disease...
  19. ncbi request reprint Preservation of spleen and brain function in children with sickle cell anemia treated with hydroxyurea
    Jane S Hankins
    Department of Hematology, Comprehensive Sickle Cell Center, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Pediatr Blood Cancer 50:293-7. 2008
    ..Chronic organ damage is an insidious process in patients with sickle cell anemia (SCA). Although hydroxyurea prevents acute vaso-occlusive events, its effects on the preservation of organ function remain undefined...
  20. ncbi request reprint Functional MRI and Wada determination of language lateralization: a case of crossed dominance
    Michele L Ries
    St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Epilepsia 45:85-9. 2004
    ....
  21. ncbi request reprint Prospective brain imaging evaluation of children with sickle cell trait: initial observations
    R Grant Steen
    Department of Diagnostic Imaging, St Jude Children s Research Hospital, 332 N Lauderdale St, Memphis, TN 38105 2794, USA
    Radiology 228:208-15. 2003
    ..To determine whether sickle cell trait (hemoglobin AS) is associated with abnormalities in the brain of asymptomatic children...
  22. pmc Functional neuroimaging to characterize visual system development in children with retinoblastoma
    Scott M Barb
    Department of Radiological Sciences, St Jude Children s Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105 2794, USA
    Invest Ophthalmol Vis Sci 52:2619-26. 2011
    ..To use functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI) to investigate visual system development in children being treated for retinoblastoma...
  23. pmc Spinal epidural lipomatosis in children with hematologic malignancies
    Rachel C Brennan
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Ann Hematol 90:1067-74. 2011
    ..Investigation for SEL in leukemia or lymphoma patients with difficult lumbar punctures is warranted. Placement of an Ommaya reservoir may facilitate safe CNS-directed therapy in severely affected patients...
  24. pmc Quantitative MRI assessment of leukoencephalopathy
    Wilburn E Reddick
    Department of Diagnostic Imaging, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Magn Reson Med 47:912-20. 2002
    ....
  25. pmc The effects of propofol on cerebral perfusion MRI in children
    Julie H Harreld
    Department of Radiological Sciences, St Jude Children s Research Hospital, MS 220, 262 Danny Thomas Place, Memphis, TN 38105 3678, USA
    Neuroradiology 55:1049-56. 2013
    ..The objectives of this study were to test for measurable differences in MR measures of cerebral blood flow (CBF) and cerebral blood volume (CBV) between non-sedated and propofol-sedated children, and to identify influential factors...
  26. doi request reprint The impact of preparation and support procedures for children with sickle cell disease undergoing MRI
    Katherine R Cejda
    Child Life Program, St Jude Children s Research Hospital, 262 Danny Thomas Place, Mail Stop 121, Memphis, TN 38105, USA
    Pediatr Radiol 42:1223-8. 2012
    ..To improve children's ability to cope with MRI examinations and avoid sedation, our institution established preparation and support procedures (PSP)...
  27. doi request reprint MRI abnormalities of the brain in one-year-old children with sickle cell anemia
    Winfred C Wang
    Department of Hematology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Pediatr Blood Cancer 51:643-6. 2008
    ..We performed MRI examinations of the brain in infants with SCA, who were evaluated as part of the multicenter randomized double-blinded Pediatric Hydroxyurea Phase III Clinical Trial (BABY HUG)...
  28. ncbi request reprint Brain metastases of malignant germ cell tumors in children and adolescents
    Sheri L Spunt
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Cancer 101:620-6. 2004
    ..Brain metastases of pediatric germ cell tumors are uncommon, and there is limited information regarding their incidence, clinical presentation, response to treatment, and influence on survival...
  29. ncbi request reprint Influence of tumor grade on time to progression after irradiation for localized ependymoma in children
    Thomas E Merchant
    Department of Radiation Oncology, St Jude Children s Research Hospital, 332 North Lauderdale Street, Memphis, TN 38105, USA
    Int J Radiat Oncol Biol Phys 53:52-7. 2002
    ..To investigate the influence of histologic grade on progression-free survival (PFS) after irradiation (RT) for pediatric patients with localized ependymoma...
  30. pmc US and MRI of pediatric ocular masses with histopathological correlation
    Rachel C Brennan
    Department of Oncology, St Jude Children s Research Hospital, MS 260, 262 Danny Thomas Place, Memphis, TN 38105, USA
    Pediatr Radiol 42:738-49. 2012
    ..Features useful in discriminating among these entities are emphasized...
  31. ncbi request reprint Cognitive impairment in children with hemoglobin SS sickle cell disease: relationship to MR imaging findings and hematocrit
    R Grant Steen
    Department of Diagnostic Imaging, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    AJNR Am J Neuroradiol 24:382-9. 2003
    ..We test a hypothesis that cognitive impairment in children with hemoglobin SS sickle cell disease is associated with low hematocrit and MR imaging abnormalities...
  32. ncbi request reprint Extranodal Rosai-Dorfman disease in children
    Carlos Rodriguez-Galindo
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    J Pediatr Hematol Oncol 26:19-24. 2004
    ..The authors describe three patients with RDD who had exclusive extranodal disease in the head and neck area, in whom the clinical presentation mimicked other more common conditions...