M Fouladi

Summary

Affiliation: St. Jude Children's Research Hospital
Country: USA

Publications

  1. ncbi request reprint Comparison of CSF cytology and spinal magnetic resonance imaging in the detection of leptomeningeal disease in pediatric medulloblastoma or primitive neuroectodermal tumor
    M Fouladi
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Clin Oncol 17:3234-7. 1999
  2. ncbi request reprint Intellectual and functional outcome of children 3 years old or younger who have CNS malignancies
    Maryam Fouladi
    Department of Hematology Oncology, St Jude Children s Research Hospital, 332 N Lauderdale, Memphis, TN 38105 2794, USA
    J Clin Oncol 23:7152-60. 2005
  3. ncbi request reprint Histone deacetylase inhibitors in cancer therapy
    Maryam Fouladi
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    Cancer Invest 24:521-7. 2006
  4. ncbi request reprint White matter lesions detected by magnetic resonance imaging after radiotherapy and high-dose chemotherapy in children with medulloblastoma or primitive neuroectodermal tumor
    Maryam Fouladi
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    J Clin Oncol 22:4551-60. 2004
  5. ncbi request reprint Clear cell ependymoma: a clinicopathologic and radiographic analysis of 10 patients
    Maryam Fouladi
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Cancer 98:2232-44. 2003
  6. ncbi request reprint Phase II study of oxaliplatin in children with recurrent or refractory medulloblastoma, supratentorial primitive neuroectodermal tumors, and atypical teratoid rhabdoid tumors: a pediatric brain tumor consortium study
    Maryam Fouladi
    St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Cancer 107:2291-7. 2006
  7. ncbi request reprint Outcome of children with centrally reviewed low-grade gliomas treated with chemotherapy with or without radiotherapy on Children's Cancer Group high-grade glioma study CCG-945
    Maryam Fouladi
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Cancer 98:1243-52. 2003
  8. pmc Amifostine protects against cisplatin-induced ototoxicity in children with average-risk medulloblastoma
    Maryam Fouladi
    Department of Oncology, St Jude Children s Research Hospital, 332 North Lauderdale, Memphis, TN 38105 2794, USA
    J Clin Oncol 26:3749-55. 2008
  9. ncbi request reprint A phase II study of the farnesyl transferase inhibitor, tipifarnib, in children with recurrent or progressive high-grade glioma, medulloblastoma/primitive neuroectodermal tumor, or brainstem glioma: a Children's Oncology Group study
    Maryam Fouladi
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Cancer 110:2535-41. 2007
  10. ncbi request reprint Phase I study of everolimus in pediatric patients with refractory solid tumors
    Maryam Fouladi
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    J Clin Oncol 25:4806-12. 2007

Research Grants

  1. Lapatinib in childhood CNS malignancies
    Maryam Fouladi; Fiscal Year: 2006

Detail Information

Publications40

  1. ncbi request reprint Comparison of CSF cytology and spinal magnetic resonance imaging in the detection of leptomeningeal disease in pediatric medulloblastoma or primitive neuroectodermal tumor
    M Fouladi
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Clin Oncol 17:3234-7. 1999
    ..To determine the validity of this hypothesis, we compared the rate of detection of LMD between concurrent lumbar CSF cytology and spinal MRI performed at diagnosis in patients with medulloblastoma or PNET...
  2. ncbi request reprint Intellectual and functional outcome of children 3 years old or younger who have CNS malignancies
    Maryam Fouladi
    Department of Hematology Oncology, St Jude Children s Research Hospital, 332 N Lauderdale, Memphis, TN 38105 2794, USA
    J Clin Oncol 23:7152-60. 2005
    ....
  3. ncbi request reprint Histone deacetylase inhibitors in cancer therapy
    Maryam Fouladi
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    Cancer Invest 24:521-7. 2006
  4. ncbi request reprint White matter lesions detected by magnetic resonance imaging after radiotherapy and high-dose chemotherapy in children with medulloblastoma or primitive neuroectodermal tumor
    Maryam Fouladi
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    J Clin Oncol 22:4551-60. 2004
    ....
  5. ncbi request reprint Clear cell ependymoma: a clinicopathologic and radiographic analysis of 10 patients
    Maryam Fouladi
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Cancer 98:2232-44. 2003
    ..Histologically, it may mimic oligodendroglioma, central neurocytoma, hemangioblastoma, and renal cell carcinoma...
  6. ncbi request reprint Phase II study of oxaliplatin in children with recurrent or refractory medulloblastoma, supratentorial primitive neuroectodermal tumors, and atypical teratoid rhabdoid tumors: a pediatric brain tumor consortium study
    Maryam Fouladi
    St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Cancer 107:2291-7. 2006
    ....
  7. ncbi request reprint Outcome of children with centrally reviewed low-grade gliomas treated with chemotherapy with or without radiotherapy on Children's Cancer Group high-grade glioma study CCG-945
    Maryam Fouladi
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Cancer 98:1243-52. 2003
    ....
  8. pmc Amifostine protects against cisplatin-induced ototoxicity in children with average-risk medulloblastoma
    Maryam Fouladi
    Department of Oncology, St Jude Children s Research Hospital, 332 North Lauderdale, Memphis, TN 38105 2794, USA
    J Clin Oncol 26:3749-55. 2008
    ....
  9. ncbi request reprint A phase II study of the farnesyl transferase inhibitor, tipifarnib, in children with recurrent or progressive high-grade glioma, medulloblastoma/primitive neuroectodermal tumor, or brainstem glioma: a Children's Oncology Group study
    Maryam Fouladi
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Cancer 110:2535-41. 2007
    ....
  10. ncbi request reprint Phase I study of everolimus in pediatric patients with refractory solid tumors
    Maryam Fouladi
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    J Clin Oncol 25:4806-12. 2007
    ....
  11. ncbi request reprint Relation between Irofulven (MGI-114) systemic exposure and tumor response in human solid tumor xenografts
    Markos Leggas
    Department of Pharmaceutical Sciences, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Clin Cancer Res 8:3000-7. 2002
    ....
  12. ncbi request reprint Comparison of lumbar and shunt cerebrospinal fluid specimens for cytologic detection of leptomeningeal disease in pediatric patients with brain tumors
    A Gajjar
    Departments of Hematology Oncology, Radiation Oncology, Pathology and Laboratory Medicine, and Biostatistics and Epidemiology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Clin Oncol 17:1825-8. 1999
    ....
  13. doi request reprint High-dose chemotherapy with autologous stem cell rescue for children with recurrent malignant brain tumors
    Chie Schin Shih
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Cancer 112:1345-53. 2008
    ..High-dose chemotherapy (HDCT) with autologous stem cell rescue (ASCR) has been reported to be effective in treating children with recurrent central nervous system (CNS) malignancies...
  14. pmc Pediatric phase I trial and pharmacokinetic study of vorinostat: a Children's Oncology Group phase I consortium report
    Maryam Fouladi
    St Jude Children s Research Hospital, Memphis, TN, USA
    J Clin Oncol 28:3623-9. 2010
    ....
  15. ncbi request reprint Results of a phase II upfront window of pharmacokinetically guided topotecan in high-risk medulloblastoma and supratentorial primitive neuroectodermal tumor
    Clinton F Stewart
    Department of Pharmaceutical Sciences, St Jude Children s Research Hospital, 332 N Lauderdale, Memphis, TN 38105 2794, USA
    J Clin Oncol 22:3357-65. 2004
    ....
  16. ncbi request reprint Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): long-term results from a prospective, multicentre trial
    Amar Gajjar
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Lancet Oncol 7:813-20. 2006
    ..We aimed to investigate the effectiveness of risk-adapted radiotherapy followed by a shortened period of dose-intense chemotherapy in children with medulloblastoma...
  17. ncbi request reprint Chromosome 17 abnormalities in pediatric neuroblastic tumor with abundant neuropil and true rosettes
    Christine Fuller
    Department of Pathology, St Jude Children s, Research Hospital, Memphis, TN, USA
    Am J Clin Pathol 126:277-83. 2006
    ..No deletions of INI1 or amplifications of MYC or MYCN were detected. This report adds 2 cases to our experience of PNTANTR and is the first to demonstrate isochromosome 17q, a molecular alteration typical of medulloblastomas...
  18. ncbi request reprint Phase I study of depsipeptide in pediatric patients with refractory solid tumors: a Children's Oncology Group report
    Maryam Fouladi
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    J Clin Oncol 24:3678-85. 2006
    ..To determine the maximum-tolerated dose (MTD), dose-limiting toxicities (DLT), pharmacokinetic profile, and pharmacodynamics of the histone deacetylase inhibitor, depsipeptide, in children with refractory or recurrent solid tumors...
  19. ncbi request reprint Polar spongioblastoma of the spinal cord: a case report
    Christine Fuller
    Department of Pathology, St Jude Children s Research Hospital, 332 N Lauderdale Street, Memphis, TN 38105, USA
    Pediatr Dev Pathol 9:75-80. 2006
    ..Discrimination of these rare aggressive lesions from other CNS tumors with focal palisaded architecture is crucial as the treatment and prognosis of the latter may differ significantly...
  20. ncbi request reprint Intratumoral hemorrhage among children with newly diagnosed, diffuse brainstem glioma
    Alberto Broniscer
    Department of Hematology Oncology, St Jude Children s Research Hospital, 332 North Lauderdale Street, Memphis, TN 38105, USA
    Cancer 106:1364-71. 2006
    ..In the current study, the authors assessed the characteristics and estimated the cumulative incidence of IH among children with BSG...
  21. ncbi request reprint Survival and late mortality in long-term survivors of pediatric CNS tumors
    E Brannon Morris
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Clin Oncol 25:1532-8. 2007
    ..To describe the pattern of survival and late mortality among contemporary long-term survivors of pediatric CNS tumor...
  22. ncbi request reprint Temozolomide after radiotherapy for newly diagnosed high-grade glioma and unfavorable low-grade glioma in children
    Alberto Broniscer
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN, USA
    J Neurooncol 76:313-9. 2006
    ..Although the heterogeneity of prognostic factors in our patients made assessment of treatment outcome more difficult, the addition of 6 cycles of temozolomide after radiotherapy did not seem to alter the poor outcome of these patients...
  23. ncbi request reprint Altered irinotecan pharmacokinetics in pediatric high-grade glioma patients receiving enzyme-inducing anticonvulsant therapy
    Kristine R Crews
    Departments of Pharmaceutical Sciences, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Clin Cancer Res 8:2202-9. 2002
    ..The purpose of this study was to determine the effect of enzyme-inducing anticonvulsants (EIAs) on the disposition of irinotecan and metabolites in pediatric patients with high-grade glioma...
  24. ncbi request reprint Survival and functional outcome of children with hypothalamic/chiasmatic tumors
    Maryam Fouladi
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Cancer 97:1084-92. 2003
    ..We evaluated the impact of clinical and neuroimaging parameters and primary therapy on overall (OS) and progression-free (PFS) survival and on neuroendocrine and neurocognitive outcome in children with H and/or C tumors...
  25. ncbi request reprint Training subspecialty nurses in developing countries: methods, outcome, and cost
    Judith A Wilimas
    International Outreach Program and St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Med Pediatr Oncol 41:136-40. 2003
    ..A major impediment to the development of such programs is a lack of trained nurses. Therefore, education of pediatric subspecialty nurses becomes a priority...
  26. pmc Phase 1 study of an oxaliplatin and etoposide regimen in pediatric patients with recurrent solid tumors
    Lisa M McGregor
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Cancer 115:655-64. 2009
    ..The combination of a platinating agent and etoposide has induced responses in various pediatric tumors. The study estimated the maximum tolerated dose (MTD) of an oxaliplatin and etoposide regimen in children with recurrent solid tumors...
  27. ncbi request reprint Medullomyoblastoma: a radiographic and clinicopathologic analysis of six cases and review of the literature
    Kathleen J Helton
    Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    Cancer 101:1445-54. 2004
    ..Medullomyoblastoma (MMB) is a rare cerebellar embryonal neoplasm that occurs almost exclusively in children. It is biphasic by microscopy, containing myoblastic and primitive neuroectodermal components...
  28. ncbi request reprint Role of temozolomide after radiotherapy for newly diagnosed diffuse brainstem glioma in children: results of a multiinstitutional study (SJHG-98)
    Alberto Broniscer
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Cancer 103:133-9. 2005
    ..The role of chemotherapy in the treatment of children with newly diagnosed diffuse brainstem glioma is uncertain. In the current study, the authors tested the efficacy of temozolomide treatment after radiotherapy (RT) in this setting...
  29. ncbi request reprint Atypical teratoid/rhabdoid tumors (ATRT): improved survival in children 3 years of age and older with radiation therapy and high-dose alkylator-based chemotherapy
    Tanya M Tekautz
    Department of Hematology Oncology, Mail Stop 260, St Jude Children s Research Hospital, 332 N Lauderdale St, Memphis, TN 38105, USA
    J Clin Oncol 23:1491-9. 2005
    ..To describe clinical features, therapeutic approaches, and prognostic factors in pediatric patients with atypical teratoid/rhabdoid tumors (ATRT) treated at St Jude Children's Research Hospital (SJCRH)...
  30. ncbi request reprint End-of-life care preferences of pediatric patients with cancer
    Pamela S Hinds
    Division of Nursing Research and Patient Care Services, Department of Hematology Oncology, Palliative and End of Life Care Task Force, and Ethics Committee, St Jude Children s Research Hospital, Memphis, TN, USA
    J Clin Oncol 23:9146-54. 2005
    ..We identified the preferences of children and adolescents with advanced cancer about their end-of-life care and the factors that influenced their decisions...
  31. ncbi request reprint Ependymoma: new therapeutic approaches including radiation and chemotherapy
    Thomas E Merchant
    Division of Radiation Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Neurooncol 75:287-99. 2005
    ..Future research in the treatment of this tumor, that afflicts fewer than 200 children in the US each year, will focus on molecular biology, clarifying risk factors for tumor control and late effects, and testing novel agents...
  32. doi request reprint Diffusion tensor imaging of brainstem tumors: axonal degeneration of motor and sensory tracts
    Kathleen J Helton
    Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    J Neurosurg Pediatr 1:270-6. 2008
    ..The authors sought to determine whether DT imaging and white matter tractography could detect axonal degeneration in patients with brainstem tumors...
  33. pmc Pleomorphic xanthoastrocytoma: favorable outcome after complete surgical resection
    M Fouladi
    Department of Hematology-Oncology, St Jude Children's Research Hospital, Memphis, TN 38105-2794, USA
    Neuro Oncol 3:184-92. 2001
    ..Gross total resection without adjuvant therapy provides prolonged disease control, as seen in 6 of 7 patients (85%) in our series...
  34. doi request reprint Endocrine outcomes for children with embryonal brain tumors after risk-adapted craniospinal and conformal primary-site irradiation and high-dose chemotherapy with stem-cell rescue on the SJMB-96 trial
    Stephen J Laughton
    Division of Neuro Oncology, Department of Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    J Clin Oncol 26:1112-8. 2008
    ....
  35. ncbi request reprint Evaluation of the antitumor efficacy, pharmacokinetics, and pharmacodynamics of the histone deacetylase inhibitor depsipeptide in childhood cancer models in vivo
    Claire Graham
    Department of Molecular Pharmacology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Clin Cancer Res 12:223-34. 2006
    ..Here, we have evaluated depsipeptide, a natural tetrapeptide HDAC inhibitor, against a panel of pediatric solid tumor models in vivo and evaluated pharmacokinetic and pharmacodynamic variables with tumor sensitivity...
  36. ncbi request reprint Population pharmacokinetics of temozolomide and metabolites in infants and children with primary central nervous system tumors
    John C Panetta
    Department of Pharmaceutical Sciences, St Jude Children s Research Hospital, 332 N Lauderdale, Memphis, TN 38105, USA
    Cancer Chemother Pharmacol 52:435-41. 2003
    ..To construct a population pharmacokinetic model for temozolomide (TMZ), a novel imidazo-tetrazine methylating agent and its metabolites MTIC and AIC in infants and children with primary central nervous system tumors...
  37. pmc Phase I trial of lapatinib in children with refractory CNS malignancies: a Pediatric Brain Tumor Consortium study
    Maryam Fouladi
    St Jude Children s Research Hospital, Memphis, TN, USA
    J Clin Oncol 28:4221-7. 2010
    ....
  38. ncbi request reprint A mechanistic mathematical model of temozolomide myelosuppression in children with high-grade gliomas
    John Carl Panetta
    Department of Pharmaceutical Sciences, St Jude Children s Research Hospital, 332 North Lauderdale St, Memphis, TN 38105 2794, USA
    Math Biosci 186:29-41. 2003
    ..This model will be useful for the prospective design of clinical trials of TMZ in children with cancer...
  39. pmc Determination of the gamma-secretase inhibitor MK-0752 in human plasma by online extraction and electrospray tandem mass spectrometry (HTLC-ESI-MS/MS)
    Feng Bai
    Department of Pharmaceutical Sciences, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Chromatogr B Analyt Technol Biomed Life Sci 878:2348-52. 2010
    ..Within-day and between-day precisions were<8.6%, and accuracies were 0.7 and 7.1%. This method was applied to the measurement of plasma MK-0752 levels in a Phase I study of pediatric patients with recurrent or refractory brain tumors...
  40. pmc Phase I trial of tipifarnib in children with newly diagnosed intrinsic diffuse brainstem glioma
    Daphne A Haas-Kogan
    University of California, San Francisco, San Francisco, CA, USA
    Neuro Oncol 10:341-7. 2008
    ..The MTD of tipifarnib with concurrent radiation is 125 mg/m(2)/dose b.i.d. One-year survival and progression-free survival estimates are 36.4% (SE 16.7%) and 9.4% (SE 6.3%), respectively...

Research Grants1

  1. Lapatinib in childhood CNS malignancies
    Maryam Fouladi; Fiscal Year: 2006
    ..These data will be used in the rational design of future phase I combination or frontline studies to improve the outcome in children with these poor prognosis tumors. ..